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A DESIGN FOR ENVIRONMENT METHODOLOGY FOR EVALUATION AND IMPROVEMENT OF DERIVATIVE CONSUMER ELECTRONIC PRODUCT DEVELOPMENT

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Journal of Systems Science and Systems Engineering 2011年第3期20卷 260-274页

作者： Tzu-An CHIANG Z.H.che.Tung-Te WANG Department of Business Administration National Taipei College of Business Department of Industrial Engineering & Management National Taipei University of Technology

Increasing environmental awareness and stringent environmental regulations have motivated many companies to incorporate ecodesign into product development. To assist companies to address the challenge, this research presents a design for environment （DfE） methodology to evaluate and improve derivative consumer electronic product development using a back-propagation neural network （BPNN） model and a technique for order preference by similarity to ideal solution （TOPSIS） method. Based on use of a BPNN, the life cycle assessment （LCA） models are developed to estimate quantities of hazardous che.ical substances and energy consumption for a derivative consumer electronic product throughout the product life cycle. A performance evaluation and improvement model for DfE is then devised based on the TOPSIS method to analyze the ecodesign performance and provide concrete improvement strategies. With the aforementioned analysis of environmental performance, an enterprise can profoundly understand and significantly enhance the relative DfE performance of a new product compared to the similar competitive products. Finally, we apply an optical mouse development project as a case to elaborate and demonstrate the effectiveness of the proposed methodology. These analytical results can let us understand the DfE performance ranking and acquire the maximum reduced quantity of each DfE criterion for each module of a new product. Meanwhile, to enhance the green competitiveness of the new product, we recommend that the engineers should decrease the area of the circuit board of the new product. In addition, the material of the USB cable for the new product should be switche. from the PVC material to the pe material.

关键词： Back-propagation neural network TOPSIS design for environment ecodesign product development

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Further Bounds for Hardy Type Differences

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Acta Mathematica Sinica,English Series 2012年第6期28卷 1091-1102页

作者： Kristina KRULI Josip peARI Dora POKAZ Faculty of Textile Technology University of Zagreb Faculty of Civil Engineering University of Zagreb

In this paper we define a functional as a difference between the right-hand side and lefthand side of the refined Boas type inequality using the notation of superquadratic and subquadratic functions and study its properties, such as exponential and logarithmic convexity. We also, state and prove improvements and reverses of new weighted Boas type inequalities. As a special case of our result we obtain improvements and reverses of the Hardy inequality and its dual inequality. We introduce new Cauchy type mean and prove monotonicity property of this mean.

关键词： Inequalities Boas inequality superquadratic function subquadratic function

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Inflammatory bowel disease:definition,epidemiology,etiologic aspects,andimmunogenetic studies

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World Journal of Gastroenterology 1998年第5期4卷 83-95页

作者： XIA Bing JBA Crusius SGM Meuwissen AS pe a Department of Gastroenterology The Second Affiliated HospitalHubei Medical UniversityWuhan 430071China Laboratory of Gastrointest in al Immunogenetics Medical FacultyFree University Ams terdam1081 BT Ams terdamThe Ne therlands

The etiology of IBD remains unclear. Environmental factors, a genetic predisposition and a disturbed immunological response all contribute to the development of the disease. Even though pathogens have not been identified as a cause of IBD, persistent infections are highly suspected, including Mycobacterium paratuberculosis and measles virus in CD, and an unknown bacterial infection and/ or bacterial products in UC. Smoking has been suggested to be a strong risk factor in CD, and in determining the clinical course of UC and CD. Disturbances of the mucosal immune system and an imbalance of immune regulation presented by cellular and/ or humoral abnormalities as well as functions of pro-inflammatory cytokines and anti-inflammatory cytokines, and other mediators were observed in IBD patients and are considered to be fundamental to the pathogenesis of IBD. Because of the multiplicity and complexity of the interactions of all these elements, it is difficult to distinguish between primary and secondary, and pathogenic and non-pathogenic phenomena[248]. With the development of transgenic and knockout rodent models, it is possible to define the critical immune elements necessary to develop IBD. Recent studies demonstrated that mucosal homeostasis is important and a defective mucosal barrier may allow unrestrained uptake of luminal antigens and pro-inflammatory molecules and thus initiate immune responses. Some evidence for an imbalance of pro-and anti-inflammatory cytokines and of Th1/Th2 lymphocytes have been found in chronic intestinal inflammation. pANCA are present in more than 70% of UC patients, but their role as a subclinical marker of UC needs to be confirmed. As to genetic factors, epidemiological studies have demonstrated the influence of genetic factors on the development of IBD by phenomena such as ethnic variations, familial aggregation, monozygotic twins versus dizygotic twins, and first degree relatives versus spouses. A genetic influence weights more for CD t

关键词： inflammatory bowel disease/epidemiology inflammatory bowel disease/etiology inflammatory bowel disease/genetics inflammatory bowel disease/immunology

Engineering the electronic structure on MXenes via multidimensional component interlayer insertion for enhanced electromagnetic shielding

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Journal of Materials Science & Technology 2023年第7期138卷 149-156页

作者： Mengqiu Huang Lei Wang Biao Zhao Guanyu che. Renchao che Laboratory of Advanced Materials Shanghai Key Lab of Molecular Catalysis and Innovative MaterialsDepartment of Materials ScienceFudan UniversityShanghai 200438China Joint-Research Center for Computational Materials Zhejiang LaboratoryHangzhou 311100China

MXene-based functional electromagnetic interference(EMI)shielding films are highly desirable for mod-ern integrated electronic and telecommunication systems in aerospace,military,artificial intelligence,and smart and wearable electronics *** this work,3D freestanding Ti_(3)C_(2)T_(x)/CNTs/Ni film assembled by 1D multi-walled carbon nanotubes(MWCNTs)/Ni and 2D Ti_(3)C_(2)T_(x)MXene sheets was synthesized by a facile vacuum filtration *** electrostatic incorporation,hexagonal nickel plates embed on the CNTs and then the CNTs/Ni insert into the Ti_(3)C_(2)T_(x)layers to form magnetized Ti_(3)C_(2)T_(x)-based functional film with a compact and laminated *** to the outstanding electron migration capacity in the highly conductive Ti_(3)C_(2)T_(x)sheet and multiple internal reflections from porous and segregated structures,the op-timized Ti_(3)C_(2)T_(x)/CNTs/Ni composite films show excellent EMI shielding effectiveness of 67.4 dB with elec-trical conductivity of 744 S cm^(-1).Surprisingly,a magnetization compensation strategy is built to boost the EMI shielding effectiveness with decreased ***,the visual magnetic coupling phenomenon and charge distribution in the heterogeneous interfaces could be observed in the recon-structed electron holography *** encouraging results shed light on novel magnetized MXene-based functional films for high-performance EMI shielding.

关键词： Ti_(3)C_(2)T_(x)MXene Magnetic modulation Electromagnetic-interference shielding Nickel flakes Freestanding film

A new perspective on immune evasion:escaping immune surveillance by inactivating tumor suppressors

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Signal Transduction and Targeted Therapy 2022年第2期7卷 337-338页

作者： Svenja Mergener Samuel peña-Llopis Translational Genomics in Solid Tumors German Cancer Consortium(DKTK)and German Cancer Research Center(DKFZ)at University Hospital EssenHufelandstrasse 55D-45147 EssenGermany Division of Solid Tumor Translational Oncology German Cancer Consortium(DKTK)and German Cancer Research Center(DKFZ)D-69120 HeidelbergGermany

Inactivating mutations in tumor suppressor genes(TSGs)are known to drive tumorigenesis by decoupling proliferation and survival from tight regulatory *** a recent study published in Science,Martin et al.1 shed light on an unappreciated role of TSGs in preventing immune evasion by demonstrating enrichment of TSG inactivation in tumor cell transplants in mice when facing an intact adaptive immune system.

关键词： suppressor immune

Enduring association between irritable bowel syndrome and war trauma during the Nicaragua civil war period:A population-based study

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World Journal of Gastroenterology 2023年第45期29卷 5953-5961页

作者： Edgar M peña-Galo Daniel Wurzelmann Javier Alcedo Rodolfo peña Loreto Cortes Douglas Morgan Department of Digestive Diseases Miguel Servet University HospitalZaragoza 50009AragonSpain Javier Alcedo Aragon Health Research InstituteIIS AragonZaragoza 50009AragonSpain Department of Mental Health Carolina PartnersDurhamNC 27707United States Department of Data Analysis CIDE(ResearchDevelopment and Epidemiology Center)Tegucigalpa 11101Francisco MorazánHonduras School of Medicine National Autonomous University of NicaraguaLeon 21000LeonNicaragua Department of Gastroenterology and Hepatology UAB University of Alabama BirminghamBirminghamAL 35233United States School of Medcine The University of North CarolinaChapel HillNC 9500United States

BACKGROUND Psychosocial and physical trauma are known risk factors for irritable bowel syndrome(IBS),including in war veterans,whereas war exposure in civilians is *** experienced two wars,1970-1990:The Sandinistas Revolution(1970s)and The Contra War(1980s).Our aim was to investigate the role of exposure to war trauma in the subsequent development of IBS in the context of an established health surveillance system(11000 households).AIM To investigate in a civilian population the relationship between exposure to war trauma and events and the subsequent development of IBS in the context of an established public health and demographic surveillance system in western *** We conducted a nested population-based,cross-sectional study focused on functional gastrointestinal disorders based on Rome II criteria.1617 adults were randomly *** Spanish Rome II Modular Questionnaire and Harvard Trauma Questionnaire were validated in *** exposure was assessed with 10 measures of direct and indirect war trauma and post-war *** exposures were defined by≥3 *** The prevalence of IBS was 15.2%[Female(F)17.1%,Male(M)12.0%],war exposure 19.3%(F 9.3%,M 36.7%),and post-traumatic stress disorder(PTSD)5.6%(F 6.4%,M 4.3%).Significant associations with IBS in the civilian population were observed(adjusted by gender,age,socioeconomic status,education):physical and psychological abuse[adjusted odds ratio(aOR):2.25;95%confidence interval:1.1-4.5],witnessed execution(aOR:2.4;1.1-5.2),family member death(aOR:2.2;1.2-4.2),and multiple exposures(aOR:2.7;1.4-5.1).PTSD was independently associated with IBS(aOR:2.6;1.2-5.7).CONCLUSION An enduring association was observed in the Nicaragua civilian population between specific civil war-related events and subsequent *** populations in regions with extended armed conflict may warrant provider education and targeted interventions for patients.

关键词： Irritable bowel syndrome Functional gastrointestinal disorders War trauma Civil war Post-traumatic stress disorder Central America

The use of UAVs for landslide disaster risk research and disaster risk management: a literature review

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Journal of Mountain Science 2021年第2期18卷 482-498页

作者： Ricardo J.GARNICA-peÑA Irasema ALCÁNTARA-AYALA Institute of Geography National Autonomous University of Mexico(UNAM)Mexico City 04510Mexico

On a global scale,from 2005 to 2019,there were 275 high-magnitude,low-frequency disasters that involved 14,172 fatalities and four million affected *** patterns have taken place during longer periods of time in recent *** paper aims to analyse the contribution of the international landslide research community to disaster risk reduction and disaster risk management in reference to the use of Unmanned Aerial Vehicles(UAVs)in a literature *** first section notes the relevance of disaster risk research contributions for the implementation of initiatives and strategies concerning disaster risk *** second section highlights background information and current applications of drones in the field of hazards and *** methodology,which included a systematic peer review of journals in the ISI Web of Science and SCOPUS,was presented in the third section,where the results include analyses of the considered *** study concludes that most current scholarly efforts remain rooted in hazards and post-disaster evaluation and *** landslide disaster risk research should be transdisciplinary in order to strengthen participation of the various relevant stakeholders in contributing to integrated disaster risk management at local,subnational,national,regional and global levels.

关键词： UAVs Landslides Disaster risk Landslide research Vulnerability Exposure Disaster risk management

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Leptin in immuno-rheumatological diseases

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Cellular & Molecular Immunology 2011年第3期8卷 203-212页

作者： Marta Vadacca Domenico pe Margiotta Luca Navarini Antonella Afeltra Department of Rheumatology and Clinical Medicine University Campus Bio-MedicoRomeItaly

Leptin is one of the most important hormones secreted by adipocytes,with a variety of physiological roles related to the control of metabolism and energy *** its discovery in 1994,leptin has attracted increasing interest in the scientific community for its pleiotropic *** of these functions is the relationship between nutritional status and immune *** structurally resembles proinflammatory cytokines,such as IL-6 and *** cytokine-like structural characteristic of leptin is implicative of its function in regulating immune *** role of leptin in regulating immune responses has been assessed in vitro as well as in clinical *** has been shown that disease conditions of reduced leptin production are associated with increased infection ***,immune-mediated disorders,such as autoimmune diseases,are associated with the increased secretion of leptin and the production of proinflammatory pathogenic *** this paper,we review the most recent advances of the role of leptin in immune-rheumatological diseases,and we discuss whether strategies aimed at modifying leptin levels could represent innovative and therapeutic tools for autoimmune disorders.

关键词： adipokines autoimmune diseases leptin rheumatic diseases

Quantification of Photosynthetic Pigments in Neopyropia yezoensis Using Hyperspectral Imagery

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Plant Phenomics 2023年第1期5卷 60-72页

作者： Shuai che.Guoying Du Xuefeng Zhong Zhaolan Mo Zhendong Wang Yunxiang Mao Key Laboratory of Marine Genetics and Breeding(Ministry of Education) College of Marine Life SciencesOcean University of ChinaQingdao266003China Key Laboratory of Utilization and Conservation of Tropical Marine Bioresource(Ministry of Education) College of Fisheries and Life ScienceHainan Tropical Ocean UniversitySanya572002China Yazhou Bay Innovation Institute Hainan Tropical Ocean UniversitySanya572025China Laboratory for Marine Biology and Biotechnology Pilot National Laboratory for Marine Science and Technology(Qingdao)Qingdao266073China

Phycobilisomes and chlorophyll-a(Chla)play important roles in the photosynthetic physiology of red macroalgae and serve as the primary light-harvesting antennae and reaction center for photosystem Ⅱ.Neopyropia is an economically important red macroalga widely cultivated in East Asian *** contents and ratios of 3 main phycobiliproteins and Chla are visible traits to evaluate its commercial *** traditional analytical methods used for measuring these components have several ***,a high-throughput,nondestructive,optical method based on hyperspectral imaging technology was developed for phenotyping the pigments phycoerythrin(pe),phycocyanin(PC),allophycocyanin(APC),and Chla in Neopyropia thalli in this *** average spectra from the region of interest were collected at wavelengths ranging from 400 to 1000 nm using a hyperspectral *** different preprocessing methods,2 machine learning methods,partial least squares regression(PLSR)and support vector machine regression(SVR),were performed to establish the best prediction models for pe,PC,APC,and Chla *** prediction results showed that the PLSR model performed the best for pe(R_(Test^(2))=0.96,MApe=8.31%,RPD=5.21)and the SVR model performed the best for PC(R_(Test^(2))=0.94,MApe=7.18%,RPD=4.16)and APC(R_(Test^(2))=0.84,MApe=18.25%,RPD=2.53).Two models(PLSR and SVR)performed almost the same for Chla(PLSR:R_(Test^(2))=0.92,MApe=12.77%,RPD=3.61;SVR:R_(Test^(2))=0.93,MApe=13.51%,RPD=3.60).Further validation of the optimal models was performed using field-collected samples,and the result demonstrated satisfactory robustness and *** distribution of pe,PC,APC,and Chla contents within a thallus was visualized according to the optimal prediction *** results showed that hyperspectral imaging technology was effective for fast,accurate,and noninvasive phenotyping of the pe,PC,APC,and Chla contents of Neopyropia in *** could benefit the efficiency of macro

关键词： prediction breeding visible