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Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry traces the geographical source of Biomphalaria pfeifferi and Bulinus forskali,involved in schistosomiasis transmission

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Infectious Diseases of Poverty 2024年第1期13卷 98-99页

作者： papa Mouhamadou gaye EI Hadj Ibrahima Ndiaye Souleymane Doucoure Doudou Sow Mapenda gaye Ndiaw Goumballa Carole Cassagne Coralie L'Ollivier Oleg Medianikov Cheikh Sokhna Stephane Ranque Aix-Marseille University IRD AP-HM SSA VITROME Marseille France VITROME International IRD-UCAD Campus Dakar Senegal Hospital-University Institut (IHU) Mediterranée Infection Marseille France Departement of Animal Biology Faculty of Sciences and Techniques UCAD Dakar Senegal Department of Parasitology-Mycology UFR Sciences de la Santé Université Gaston Berger Saint-Louis Senegal

Background Freshwater snails of the genera Bulinus spp.,Biomphalaria spp.,and Oncomelania *** the main intermediate hosts of human and animal *** of these snails has long been based on mor-phological and/or genomic criteria,which have their *** limitations include a lack of precision for the morphological tool and cost and time for the DNA-based ***,Matrix-Assisted Laser Desorp-tion/lonization Time-Of-Flight(MALDI-TOF)mass spectrometry,a new tool used which is routinely in clinical microbi-ology,has emerged in the field of malacology for the identification of freshwater *** study aimed to evaluate the ability of MALDI-TOF MS to identify Biomphalaria pfeifferi and Bulinus forskali snail populations according to their *** This study was conducted on 101 *** and 81 *** snails collected in three distinct geo-graphical areas of Senegal(the North-East,South-East and central part of the country),and supplemented with wild and laboratory *** which had previously been morphologically described were identified by MALDl-TOF MS[identification log score values(LSV)≥1.7],after an initial blind test using the pre-existing *** DNA-based identification,new reference spectra of ***(n=10)and ***(n=5)from the geographical areas were added to the MALDI-TOF spectral *** final blind test against this updated database was per-formed to assess identification at the geographic source *** MALDI-TOF MS correctly identified 92.1%of 101 *** snails and 98.8%of 81 *** *** the final blind test,88%of 166 specimens were correctly identified according to both their species and sampling site,with LSVs ranging from 1.74 to *** geographical source was adequately identified in 90.1%of 91 *** and 85.3%of 75 *** *** Our findings demonstrate that MALDI-TOF MS can identify and differe

关键词： Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry Snail Intermediate host Biomphalaria pfeifferi Bulinus forskali Schistosomiasis Senegal

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Video Games and School Performances of Dakar High School Students

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Open Journal of Applied Sciences 2024年第7期14卷 1851-1862页

作者： Souleymane Diallo papa Mamadou gaye National Higher Institute of Popular Education and Sport (INSEPS) UCAD Dakar Senegal

The triptych (Smartphones, Video games, adolescents) has imposed itself on the collective consciousness in the form of questioning to the point of becoming a social phenomenon. It thus raises concerns about the uses that adolescents make of it and the effects on their academic performance, which we proposed to study among middle school students from the Dakar academy inspection. Where appropriate, we used mixed methods with the collection techniques of questionnaire survey, semi-structured interviews respectively with middle school students, adults (parents, supervisors, teachers, etc.), participant observation and literature review. Concretely, before accessibility to video games, the middle school students were more idle and well-behaved, watched a lot of TV, played with their brothers and sisters or did household chores. The majority of young people had good, very good or excellent conduct and their averages were fair, fairly good or good. With access to a diverse digital environment, middle school students have passionately turned to video games. As a result, their learning time, concentration and submission to parental injunctions have declined significantly. This situation negatively affected their academic performance and encouraged bad behavior.

关键词： Digital Revolution Video Games Middle School Student Education Academic Performance

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Synthesis, Spectroscopic Studies and X-Ray Diffraction of Heptacoordinated Mn(II) and Co(II) Complexes with Ligands Derived from Carbonohydrazide

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Open Journal of Inorganic Chemistry 2019年第4期9卷 35-52页

作者： Thierno Moussa Seck Adama Sy Djiby Lo papa aly gaye Mohamed Lamine Sall Ousmane Diouf Mahy Diaw Mohamed gaye Department of Chemistry University Cheikh Anta Diop Dakar Senegal Department of Chemistry University Gaston Berger Saint-Louis Senegal Department of Chemistry University Assane SECK Ziguinchor Senegal

The ligand 1-(1-(pyridin-2-yl)ethylidene)carbonohydrazide (H4L1) and 1-(pyridin-2-ylmethylene)carbonohydrazide (H4L2) were prepared by reaction of carbonohydrazide with 2-acetylpyridine or pyridine carbaldehyde respectively in a reflux methanol solution. The complexes are prepared by reaction of the ligand with the appropriate metal salt. These complexes are well characterized by elemental analysis, IR and UV spectroscopies and their structure were determined by single X-ray diffraction technic. In the crystal of the dinuclear complex [Mn2(H4L1)2(H2O)4]·Cl4, 1) each Mn(II) center is seven coordinated by two nitrogen atom and one carbonyl atom of the one ligand and one nitrogen atom and one carbonyl oxygen atom of another ligand molecule. The coordination sphere is completed by two water molecules. Each of the carbonyl oxygen atom acts as bridge between the two Mn(II) centers. In the mononuclear complex [Co(H4L2)(NO3)(H2O)2]·(NO3);2) the Co(II) center is heptacoordinated. The ligand acts in tridentate fashion through two nitrogen atoms and one carbonyl oxygen atom. Two water molecules lie in the apical positions. One nitrate group acts in bidentate manner while the other nitrate group remains uncoordinated. In both complexes the coordination polyhedral are best described as a pentagonal bipyramid. The molecules are linked together in each case by multiple hydrogen bond interaction resulting in a three-dimensional network. The crystallographic data has been deposited in Cambridge Crystallographic Data Centre [CCDC No. 1944387 (complex 1) and 1944386 (complex 2)].

关键词： Carbonohydrazide Manganese Cobalt Complex X-Ray Diffraction

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Eyelid Wounds: Epidemiological, Clinical and Etiological Aspects

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Open Journal of Ophthalmology 2024年第1期14卷 55-62页

作者： aly Mbara Ka Jean Pierre Diagne Aissatou Aw El Hadji Malick Sy Soda Mbaye Hawo Madina Diallo Audrey Samra Aboubacry Sadikh Sow Joseph Matar Mass Ndiaye Ousmane Ndiaga Senghor Lamine Ndiaye Mohamed Ndiaye Serigne Sohibou gaye papa Amadou Ndiaye Ophthalmology Department of Abass Ndao Hospital Dakar Senegal Ophthalmology Department of Aristide Le Dantec Hospital Dakar Senegal

Purpose: The aim is to show epidemiological, clinical and etiological characteristics of palpebral wounds. Methodology: This was a retrospective study focusing on patients with an eyelid wound, over a 10-year period from 2012 to 2021. We collected and analyzed the data using Excel. Results: The frequency of eyelid wounds was 0.1%. The average age of our patients was 19.38 years with a range of 1 and 62 years. The sex ratio was 3.7. Eighty-one percent of patients lived in Dakar. Fifty-seven percent (57%) of patients consulted less than 24 hours after the trauma and 7% of patients on D1. The circumstances were brawls (11%), domestic accidents (9%), road accidents (6%), and work accidents (6%). We noted 1 case of dog bite. Thirteen patients presented with post-traumatic decreased visual acuity. Involvement of the isolated upper eyelid was noted in 40% of cases and both eyelids in 15% of cases. Involvement of the lacrimal ducts was noted in 17% of cases, and that of the free edge in 21% of cases. Eyelid wounds were associated with eyeball damage in 21% of cases. Various associated lesions were observed. Ninety-one percent of patients received surgical treatment. Three cases of superinfections, 1 case of conjunctival granuloma and 1 case of phthysis of the eyeball with postoperative retinal detachment were noted. Conclusion: Eyelid sores are relatively common in our context. They require rapid surgical treatment in order to preserve the functional and aesthetic prognosis. .

关键词： Eyelid Wounds Epidemiology Clinic Etiologies

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人类活动与生态水文因素对塞内加尔北部费罗临时池塘周边的草本植物区系物种多样性的影响

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Journal of Plant Ecology 2022年第1期15卷 26-38页

作者： Ndiabou Faye aly Diallo Moustapha BassimbéSagna Jean Luc Peiry papa Saliou Sarr Aliou Guisse Département de Biologie Végétale UniversitéCheikh Anta DiopDakarSenegal IRL3189 Environment SantéSociétésCentre National de la Recherche Scientifiques(CNRS)ParisFrance IRL3189 Environnement SantéSociétésUniversitéCheikh Anta DiopDakarSenegal Observatoire international Hommes Milieux-OHMi Tessekere UniversitéCheikh Anta DiopDakarSenegal Observatoire international Hommes Milieux-OHMi Tessekere Centre National de la Recherche Scientifique(CNRS)ParisFrance Departement d’Agroforesterie UniversitéAssane Seck de ZiguinchorZinguinchorSenegal Département de Géographie Universitéde Clermont FerrandClermont-FerrandFrance Japan International Research Center for Agricultural Sciences(JIRCAS) TsukubaIbarakiJapan

在萨赫勒,临时池塘在保护物种多样性方面起着重要作用。本研究考察了塞内加尔北部费罗地区的两个放牧池塘以及一个未放牧池塘,探讨了人类活动与生态水文因素对池塘周边植物多样性的影响。每个池塘建立两条植物生态样带,确定并记录每条... 详细信息

在萨赫勒,临时池塘在保护物种多样性方面起着重要作用。本研究考察了塞内加尔北部费罗地区的两个放牧池塘以及一个未放牧池塘,探讨了人类活动与生态水文因素对池塘周边植物多样性的影响。每个池塘建立两条植物生态样带,确定并记录每条样带上平均植被单元情况(包括植被覆盖度、土壤暴露度、土壤质地、土壤湿度和酸碱度、平均高度以及坡度等)。研究结果表明,3个池塘周边共有草本植物22科41属55种。放牧池塘周边多为禾本科植物,尤其是画眉草属(Eragrostis tremula)与肠须草属(Enteropogon prieurii)植物,未放牧池塘周边则主要为其他科类植物,如牛膝属(Achyranthes sp.)、鸭跖草属(Commelina forsskaolii)、黄麻属(Corchorus sp.)植物等。Wendu Marodi池塘(未放牧池塘)的香农物种多样性指数(H′)为4.9,略高于Belel Lougal池塘和Belel Sow池塘(放牧池塘),这两个池塘的香农物种多样性指数分别为4.8和4.5。3个池塘的种类平均性指数相对都较高,分别为0.85、0.83和0.78。根据生态因子可分出4个物种群:蒺藜(Tribulus terrestris)种群,集中在限牧区与过度放牧区;平枝马唐(Digitaria horizontalis)种群与孟仁草(Chloris barbata)种群,见于过度带;以及土牛膝(Achyranthes aspera)种群,生长在人类活动较少且草本植物丰富的湿地。本研究强调了维持未放牧池塘或半保护池塘与放牧池塘景观镶嵌结构的重要性,以保护塞内加尔中心与萨赫勒地区草本植物的多样性。

关键词：池塘费罗放牧草本植被样带

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Mortality of Children with Mechanical Valve Prostheses at the CUOMO Cardio-Pediatric Center of University National Hospital of Fann (Dakar)

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World Journal of Cardiovascular Diseases 2023年第9期13卷 520-526页

作者： Momar Dioum papa Amath Diagne Amina Hanfaoui Cheikh gaye Ismael I.B. Hanifa papa Ousmane Ba Magalie Kaya papa Salmane Ba Amadou Gabriel Ciss Department of Cardiology CHU FANN Dakar Senegal Department of Thoracic and Cardiovascular Surgery CHU FANN Dakar Senegal

Introduction: Mechanical valve replacement in pediatric age is a dreaded but sometimes inevitable surgery. The purpose of this study was to determine the mortality of children with mechanical valve prostheses in the short, medium and long term. Patients and Methods: This was a retrospective and descriptive study conducted at the CUOMO cardio-pediatric center at Teaching National Hospital of Fann between January 1st, 2017 and December 31st, 2021. We included, children whose age is less than or equal to 16 years of age and who have benefited from a mechanical valve replacement and with a follow-up period of more than 6 months post-operative in the CUOMO cardio-pediatric center. Patients whose age at the time of surgery was over 16 years were excluded;patients who have benefited from bioprosthesis or valvular plastic surgery alone;as well as patients for whom a follow-up of more than 6 months was not found. Statistical analyses were carried out using the SPSS (Statistical Package for Social Science) software version 18 to calculate averages and percentages. Results: We included 85 patients. The average age was 12.84 ± 2.52 years. The male gender predominated with a sex ratio of 1.65. Dyspnea was found in 96.47% of children. Pure mitral regurgitation was the most common valve disease found in 67.06%. Rheumatic etiology was noted in 87.06% of cases. Mono valve replacement was performed in 84.71% of patients and double valve replacement in 15.3% of cases. Major mechanical complications were reported in 8 patients including 5 severe aortic mismatch cases. Hemorrhagic complications were observed in 4 patients requiring surgery. Hemodynamic complications were dominated by right ventricle dysfunction in 14 patients. Supraventricular rhythm disorders were present in 11 patients and one case of ventricular tachycardia. We found six cases of infectious endocarditis. Eight deaths were recorded with a mortality rate of 5.88%. Significant predictors of mortali

关键词： Morbidity Mortality Mechanical Valve Children Dakar

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Comparative Effect of Adding Synthetic Citric Acid to Natural Lemon Juice (Citrus aurantiifolia) on the Stability of Hibiscus Drinks Stored at 4°C and 37°C

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Food and Nutrition Sciences 2023年第6期14卷 495-508页

作者： papa Guedel Faye Ibrahima Diouf Medoune gaye Sarr Oumou Hany Sourang Nicolas Cyrille Ayessou Mady Cisse Water Energy Environment and Industrial Processes Laboratory (LE3PI) Polytechnic School of Dakar Chemical Engineering and Applied Biology Department Cheikh Anta Diop University Dakar Senegal Center for Studies on Food Security and Functional Molecules (CESAM) Dakar Senegal

The general objective of the work is to compare the effect of the addition of synthetic citric acid compared to the addition of natural fruit juice of Citrus aurantiifolia on the conservation of drink based on red chalice H. sabdariffa. The tests were carried out over a period of 5 weeks at 4°C and 37°C with seven batches of beverage samples prepared at the rate of a calyx/water ratio of 1/40 (kg·kg-1) and added respectively citric acid at 1, 2 and 4 g·L-1 and lemon juice at 10, 20 and 40 mL·L-1. The characterization of the different batches of beverages was carried out from day one. A follow-up of the residual anthocyanin content and the intensity of the red coloring were carried out over five weeks. The anthocyanin concentration was determined by the pH-differential method. The red color degradation index is determined based on the CIELAB color system (L*, a*, b* and L*). R and Minitab 18 software was used for data processing. The results of the monitoring of the parameters showed that the concentration of 1 g AC L-1 retains 2.7 mg more of the anthocyanins than adding 10 mL JC L-1 and longer maintains red color when stored at 4°C and 37°C/5 weeks. The 2 g AC L-1 and 4 g AC L-1 ratios have the same effects as the addition of 20 and 40 mL of lemon juice, all accelerating the degradation of anthocyanins and the red color. After 5 weeks of storage at 37°C, the effect of the temperature combined with the increase in the acidity of the samples (2 to 4 g AC L-1 and 20 to 40 ml JC L-1), have accelerated the total disappearance of the red color on all samples.

关键词： Stabilization Drink Citric Acid Citrus aurantiifolia Hibiscus sabdariffa Coloring

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Surgical Management of Uterine Fibroids: About 175 Cases

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Open Journal of Obstetrics and Gynecology 2023年第3期13卷 481-489页

作者： Ngom papa Malick Faye Marie Edouard gaye Yaye Fatou Sylla Mafing Aya Niang Ndama Samb Abdoulaye Ndiogou Bentaleb Hajar Inzale Mohamed Amine Koné Madjiguène Department of Obstetrics Gynecology Hospital Principal Dakar Dakar Senegal Department of Anesthesia Hospital Principal Dakar Dakar Senegal

Background: Uterine fibroids are a common condition in Senegal and often symptomatic. Our study aims to determine the epidemiological profile, to clarify the diagnostic aspects and to evaluate the surgical management of patients with uterine fibroids. Patients and Method: We carried out a retrospective and descriptive study carried out over a period of 30 months, from August 1, 2017 to January 31, 2020, concerning all patients who underwent surgery for the treatment of uterine myomatosis in the department of Gynecology Obstetrics of the Hospital Principal of Dakar. The data was collected from the patients’ medical records and analyzed using Excel version 2016 and R version 4 software. Results: We collected 175 surgical interventions for uterine fibroids, representing 44.7% of gynecological interventions. Most of the patients were between 30 and 39 years old, with an average age of 39 years. The nulliparous were the majority with 64.6%. The clinical symptomatology was represented by genital bleeding (32.6%), pelvic pain (18.85%) and infertility (12.6%). The diagnosis was confirmed by pelvic ultrasound in all patients with variable myoma topography. A myomectomy was performed in 82.3% of cases and a total hysterectomy in 17.7%. The postoperative course was simple in 94.2% of cases, and the results of treatment revealed a disappearance of symptoms in 94.3% of cases. Conclusion: Surgery occupies a prominent place in the management of uterine fibroids.

关键词： Uterine Fibroid Myomectomy Pelvic Ultrasound

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Rhegmatogenous Retinal Detachment in One-Eyed Patients: Therapeutic and Prognostic Challenges

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Open Journal of Ophthalmology 2023年第1期13卷 64-72页

作者： El Hadji Malick Sy Aïssatou Aw aly Mbara Ka Jean Pierre Diagne Hawo Madina Diallo Audrey Samra Soda Mbaye papa Amadou Ndiaye Ophtalmology Department of Abass NDAO Hospital Cheikh Anta Diop University Dakar Senegal

Background: Retinal detachment is a major ophthalmologic emergency. The rhegmatogenous form is the most common and its management is exclusively surgical as soon as possible. This urgency becomes major and absolute when it occurs in a particular monocular vision. Purpose: To analyze the clinical forms of rhegmatogenous retinal detachment (RRD), the results and the complications of their management in monophthalmic patients. Methodology: This was a retrospective and analytical study from June 2007 to December 2019. We included all patients who received a consultation for rhegmatogenous retinal detachment. All patients were seen by at least two posterior segment specialists and all were operated on by the same surgeon. Results: 57 files (57 eyes) were collected with an average age of 44.71 years and a sex ratio of 7.14. The average consultation time is 40.80 days. Patients complained of decreased visual acuity in 96.49% of cases. We had myopia in 49.12% of cases and 91.23% of patients were phakic. Retinal holes were found in 31.58% of our patients and giant tears in 17.54%. The mean retinal detachment extension was 2.52 quadrants and the macula was raised in 32 cases. The average time taken to take charge was 10 days. Detachment surgery was performed in 42 patients with 100% anatomical recovery. Conclusion: Retinal detachment in one-eyed patient is a major ophthalmic emergency. Its management must not suffer from any delay. Post-operative outcomes are relatively similar between the internal and external pathways. In one-eyed patient, silicone can be left alone in the absence of complications.

关键词： Rhegmatogenous Retinal Detachment One-Eyed Patient Intraocular Surgery Episcleral Surgery Post-Operative Results Complications

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Overview of Ductal Carcinoma <i>in Situ</i>of the Breast

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Journal of Cancer Therapy 2014年第2期5卷 222-224页

作者： papa Macoumba gaye Abdoul Aziz Kassé Institut du Cancer de Dakar Dakar Senegal

We review relevant publications on ductal carcinoma in situ of the breast in the past three years and we discuss pattern of outcome lightened by new molecular approach and techniques of radiotherapy.

关键词： DCIS Radiotherapy Treatment

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