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Journal of Geriatric Cardiology 2024年第1期21卷 90-103页

作者： Cheng-yan HU yan-ling WANG Zhen-Xing FAN Xi-peng SUN Shuai WANG Zhi LIU Department of Geriatrics Fu Xing HospitalCapital Medical UniversityBeijingChina Department of Cardiology Xuanwu Hospital Capital Medical UniversityBeijingChina Emergency Department of Xuanwu Hospital Capital Medical UniversityBeijingChina

Objective To investigate the impact of CYP2C19 gene polymorphism on clopidogrel reactivity and its association with longterm clinical outcome in patients with coronary heart disease(CHD)undergoing percutaneous coronary intervention(PCI).Methods In total,675 patients were *** on the platelet inhibition rate,patients were categorized into two groups:clopidogrel low responsiveness(CLR)and normal clopidogrel responsiveness(NCR).The CLR group was divided into ticagrelor and clopidogrel group based on the antiplatelet drugs used in the follow-up *** were classified into three groups(normal metabolizer,intermediate metabolizer,and poor metabolizer)based on the CYP2C19 *** aimed to evaluate the impact of CYP2C19 gene polymorphism on clopidogrel *** cumulative rates of 12-month all-cause deaths,major adverse cardiovascular events(MACCEs),and bleeding events were *** CLR was observed in 44.4%of the overall *** differences were observed in the platelet inhibition rate of clopidogrel among the three metabolic genotypes(P0.05).Conclusions Low response to clopidogrel in CHD patients is correlated with CYP2C19 gene ***2C19 genotyping combined with platelet reactivity is an independent predictor of 12-months MACCEs in patients with clopidogrel treatment after PCI,which is better than either test alone.

关键词： CYP2C19 drugs PCI

Thermal and mechanical behavior of casting copper alloy wheel during wheel and belt continuous casting process

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China Foundry 2024年第1期21卷 82-90页

作者： Kun Gao yan peng School of Mechanical Engineering Yanshan UniversityQinhuangdao 066004HebeiChina

To investigate the thermal and mechanical behavior of casting wheel,a two-dimensional thermoelastic-plastic finite element model was used to predict the temperature,stress and distortion distribution of the casting wheel during the wheel and belt continuous casting *** effects of grinding thickness and casting speed on the thermal and mechanical behaviors of the center of the hot face of the casting wheel were discussed in *** each rotation,the casting wheel passes through four different spray *** results show that the temperature distribution of the casting wheel in different spray zones is similar,the temperature of the hot face is the highest and the temperature reaches the peak in the spray zoneⅢ.The stress and distortion depend on the temperature distribution,and the maximum stress and distortion of the hot face are 358.2 MPa and 1.82 mm,*** temperature at the center of the hot face decreases with increasing grinding thickness and increases with increasing casting speed.

关键词： casting wheel finite element model grinding thickness casting speed hot face spray zones

Do credit constraints affect households'economic vulnerability?Empirical evidence from rural China

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Journal of Integrative Agriculture 2021年第9期20卷 2552-2568页

作者： peng yan-ling yanjun REN LI Hou-jian College of Economics Sichuan Agricultural UniversityChengdu 611130P.R.China Department of Agricultural Markets Leibniz Institute of Agricultural Development in Transition EconomiesHalle(Saale)06120Germany

Poverty alleviation is still one of the major challenges in developing countries,especially in transitional economy like *** the perspective of anti-poverty,this paper examines the impact of formal credit constraints(FCCs)and informal credit constraints(IFCCs)on economic vulnerability(EV)using the data from the China Household Income Project(CHIP)survey for 2013(CHIPs 2013)of rural *** potential endogeneity problem of credit constraints(CCs)is addressed by applying the control function approach within an ordered probit *** results show that both FCCs and IFCCs have a robust positive and significant impact on the EV of rural households and that the impact of FCCs is greater than that of *** identify the potential mechanisms through which CCs affect EV,the seemingly unrelated regressions are used and the potential intercorrelation among these mechanisms is *** find that the impact of CCs on EV is partly mediated by health,trust,per capita financial assets and per capita income,whereby health and per capita income contribute to most of the total indirect ***,policies focus on supply-side and demand-side to improve credit accessibility could reduce rural households'EV,especially through its positive effect on health and per capita income.

关键词： credit constraints economic vulnerability causal mediation mechanisms rural China

Numerical simulation of fluid flow and free surface fluctuations during wheel and belt casting process

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Journal of Iron and Steel Research(International) 2024年第5期31卷 1117-1126页

作者： Kun Gao yan peng National Engineering Research Center for Equipment and Technology of Cold Strip Rolling Yanshan UniversityQinhuangdao066004HebeiChina

The unstable fluid flow and severe free surface fluctuations in the wheel and belt caster can affect the quality of the cast *** lower level height tends to entrap inclusions in the molten *** the other hand,the higher level height makes the production process more dangerous due to the overflow of high temperature fluid from the mold.A computational model of the molten metal pouring process was *** transient fluid flow and free surface fluctuations behavior were calculated using the three-dimensional large eddy simulation model and the volume of fluid *** results show that the flow velocity of the main jet gradually decreases under the influence of the low kinetic energy fluid in the *** is an obvious oscillation in the tail of the jet,while the flow field is asymmetric in *** jet is closer to the inside radius side due to the Coanda effect,and there is a recirculation zone on the inside radius and the outside radius respectively,according to the 10 s time-averaged *** with the industrial observation and simulation results,the shape of the free surface is a wave that varies with *** addition,the free surface height is lowest and the flow velocity is highest in the region near the jet.

关键词： Fluid flow Free surface Wheel and belt caster Large eddy simulation Volume of fluid method

Simple preparation of C(CS)/g-C_(3)N_(4)/Co carbon aerogel and its catalytic performance for ammonium perchlorate

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Defence Technology（防务技术） 2024年第3期33卷 186-196页

作者： Yujie yan Bo Jin Rufang peng State Key Laboratory of Environment-friendly Energy Materials School of Materials Science and EngineeringSouthwest University of Science and TechnologyMianyang621010China

Biomass chitosan(CS)was used as a template,graphitic phase carbon nitride(g-C_(3)N_(4))with high nitrogen content and certain catalytic activity was used as a dopant,and nano-transition metal cobalt(Co)was used as a catalytic center *** carbon aerogel(C(CS)/g-C_(3)N_(4)/Co)with a three-dimensional network-like structure was prepared by assembling the three materials through experimental operations such as freeze-drying and high-temperature *** was demonstrated by scanning and transmission characterization that the CS in the carbon aerogel could provide more active sites for the cobalt nanoparticles,and the doping of graphite-phase carbon nitride as a template dispersed the cobalt nanoparticles and changed the conductivity of the *** investigate the catalytic effect of carbon aerogel on ammonium perchlorate(AP),it was investigated by differential thermal analyzer and TG thermal *** carbon aerogel was very effective in catalyzing AP,and the 10 wt% content of the catalyst reduced the AP pyrolysis peak from 703.9 to 595.5 *** to further investigate the synergistic effect of the three materials,further carbon aerogels such as C(CS)/Co,g-C_(3)N_(4)/Co were prepared and applied to catalyze AP,and the same ratio reduced the AP pyrolysis peak by 98.1℃ and 97.7℃.This result indicates a synergistic effect of the assembly of the three materials.

关键词： g-C_(3)N_(4) Chitosan Co Ammonium perchlorate Pyrolysis kinetics

ANALYTICAL STUDY ON FLOW PROCESS OF FLOATING-OIL RECOVERY DEVICE FROM OIL-CONTAMINATED SEAWATER BY MHD METHOD

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Journal of Hydrodynamics 2007年第2期19卷 195-200页

作者： ZHANG Guo-yan peng yan ZHAO ling-zhi LI Ran SHA Ci-wen Institute of Electrical Engineering Chinese Academy of Sciences Beijing 100080 China

A new method of recovering maritime oil-spill based on electromagnetic force, the so-called MHD oil-spill recovery method was proposed in the IEECAS. The operating process of MHD channel was described in this article. Numerical study was carried out using a two-dimensional water-air two-phase model and the VOF method. The agreement between the numerical and the experimental results was reached.

关键词： numerical simulation water-air two phaseflow VOF method MHD

Cooperative control for heterogeneous multi-agent systems: progress, applications, and challenges

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Science China(Information Sciences) 2024年第5期67卷 318-320页

作者： Bing yan peng SHI Jonathon CHAMBERS School of Electrical and Mechanical Engineering Faculty of Science Engineering and TechnologyThe University of Adelaide School of Engineering College of Science and Engineering University of Leicester

Cooperative control for heterogeneous multi-agent systems(MASs) is a critical and rapidly evolving field in modern automation and robotics. Characterized by the integration of agents with diverse capabilities and func... 详细信息

关键词： Multi agent systems

Automatic detection of small bowel lesions with different bleeding risks based on deep learning models

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World Journal of Gastroenterology 2024年第2期30卷 170-183页

作者： Rui-Ya Zhang peng-peng Qiang ling-Jun Cai Tao Li yan Qin Yu Zhang Yi-Qing Zhao Jun-Ping Wang Department of Gastroenterology The Fifth Clinical Medical College of Shanxi Medical UniversityTaiyuan 030012Shanxi ProvinceChina School of Computer and Information Technology Shanxi UniversityTaiyuan 030006Shanxi ProvinceChina School of Life Sciences and Technology Mudanjiang Normal UniversityMudanjiang 157011Heilongjiang ProvinceChina

BACKGROUND Deep learning provides an efficient automatic image recognition method for small bowel(SB)capsule endoscopy(CE)that can assist physicians in ***,the existing deep learning models present some unresolved *** To propose a novel and effective classification and detection model to automatically identify various SB lesions and their bleeding risks,and label the lesions accurately so as to enhance the diagnostic efficiency of physicians and the ability to identify high-risk bleeding *** The proposed model represents a two-stage method that combined image classification with object ***,we utilized the improved ResNet-50 classification model to classify endoscopic images into SB lesion images,normal SB mucosa images,and invalid ***,the improved YOLO-V5 detection model was utilized to detect the type of lesion and its risk of bleeding,and the location of the lesion was *** constructed training and testing sets and compared model-assisted reading with physician *** The accuracy of the model constructed in this study reached 98.96%,which was higher than the accuracy of other systems using only a single *** sensitivity,specificity,and accuracy of the model-assisted reading detection of all images were 99.17%,99.92%,and 99.86%,which were significantly higher than those of the endoscopists’*** image processing time of the model was 48 ms/image,and the image processing time of the physicians was 0.40±0.24 s/image(P<0.001).CONCLUSION The deep learning model of image classification combined with object detection exhibits a satisfactory diagnostic effect on a variety of SB lesions and their bleeding risks in CE images,which enhances the diagnostic efficiency of physicians and improves the ability of physicians to identify high-risk bleeding groups.

关键词： Artificial intelligence Deep learning Capsule endoscopy Image classification Object detection Bleeding risk

Recovery of scandium from silicate minerals by high-pressure leaching in sulfuric acid

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Journal of Rare Earths 2024年第7期42卷 1375-1384,I0007页

作者： peng yan Xiaoming Chen Likun Gao Bo yang Faculty of Metallurgical and Energy Engineering Kunming University of Science and TechnologyKunming650093China Faculty of Land Resources Engineering Kunming University of Science and TechnologyKunming650093China School of Chemistry and Chemical Engineering Kunming UniversityKunming650214China

This study investigated the leaching of scandium from a Sc-bearing silicate *** Sc concentrate obtained by beneficiation pre-enrichment has 1.03×10^(−4) wt%Sc and 14.66 wt%*** main Sc-bearing minerals are limonite,chlorite,sericite,and hornblende,in the form of ***-pressure leaching(HPL)with sulfuric acid(98 wt%)and NaF was used to dispose this *** Sc leaching efficiency of 91.82%was obtained under the optimum conditions,which are pressure of 5.0×10^(5) Pa,A/O value of 1.1,L/S value of 1.8,NaF dosage of 2 wt%,at 130℃ for 6 *** X-ray diffraction(XRD)and scanning electron microscopy(SEM)results show that the residue is mainly quartz phase in the multi-hole *** with ordinary leaching for silicate,high-pressure leaching has significant advantages in saving acid and energy consumption.

关键词： Silicate minerals Scandium High-pressure Leaching Concentrated sulfuric acid Rare earths

Clinical analysis of multiple primary gastrointestinal malignant tumors:A 10-year case review of a single-center

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World Journal of Gastrointestinal Oncology 2024年第4期16卷 1204-1212页

作者： Cheng-Lou Zhu ling-Zhi peng The First School of Clinical Medicine Lanzhou UniversityLanzhou 730000Gansu ProvinceChina Department of Surgical Oncology Gansu Provincial HospitalLanzhou 730000Gansu ProvinceChina

BACKGROUND Multiple primary malignant tumors(MPMTs)was first described by Billroth as early as 1889,with the first report published by Warren and Gates in *** then,numerous cases have been reported.A literature review of 1104269 patients with cancer revealed that the incidence of MPMTs ranged from 0.73 to 11.7%.In recent years,however,there has been a significant upward trend in the incidence of this phenomenon,which may be associated with many different factors,including the advancement of modern diagnostic procedures facilitating the examination and diagnosis of more MPMTs,increased exposure to chemotherapy and radiotherapy that exacerbate the risk of new malignant tumors in patients with cancer,and prolonged survival of patients with cancer allowing sufficient time for the development of new primary *** To analyze the incidence,clinical features,treatment factors,prevalence,and prognosis of patients with MPMTs in the gastrointestinal tract treated in a single ***,we analyzed the different tumor combinations,time interval between the occurrence of tumors,and *** This retrospective cohort study analyzed 8059 patients with pathologically confirmed gastrointestinal malignant tumors treated at the Gansu Province Hospital in Lanzhou,Gansu,China between June 2011 and June *** these,85 patients had *** clinical features,treatment factors,prevalence,and prognosis of this latter cohort were *** The incidence of MPMTs in patients with gastrointestinal malignant tumors was 1.05%(85/8059),including 83 double primary malignant tumors and two triple primary malignant tumors of which 57(67.06%)were synchronous MPMTs(SMPMTs)and 28(32.94%)were metachronous MPMTs(MMPMTs).The most frequent associations were found between the rectum colon cancers within the SMPMT category and the gastric-colon cancers within the MMPMT *** the MMPMTs,the median interval was 53 *** overall 1-,3-and 5-year survival rates f

关键词： Multiple primary malignant tumors Clinical characteristics Gastrointestinal tract Prognosis Epidemiology