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KIR and a specific HLA-C gene are associated with susceptibility and resistance to hepatitis B virus infection in a Brazilian population

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Cellular & Molecular Immunology 2014年第6期11卷 609-612页

作者： Patricia Araujo Giovana Goncalves Flavia Latini orlando Ferreira Luis Cristovao Porto Jose Augusto Barreto Manoel Joao Castelo Girao Ricardo Sobhie Diaz Colsan - Associacao Beneficente de Coleta de Sangue Sao Paulo SP Brazil Department of Gynecology Federal University ofao Paulo (UNIFESP) Sao Paulo SP Brazil Molecular Virology Laboratory Biology Institute Federal University of Rio de Janeiro (UERJ) Rio de Janeiro R J Brazil Histocompatibility and Cryopreservation Laboratory Federal University of Rio de Janeiro (UERJ) Rio de Janeiro R J Brazil Retrovirology Laboratory Federal University of Sao Paulo (UNIFESP) Sao Paulo SP Brazil

BRIEF REPORT The activity of natural killer （NK） cells is partially regulated by killer cell immunoglobulin-like receptors （KIRs） interacting with human leukocyte antigen C （HLA-C） ligands.1 The ligands of sever... 详细信息

关键词： infection Brazilian population

Precipitation analysis of as-cast HK40 steel after isothermal aging

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International Journal of Minerals,Metallurgy and Materials 2017年第10期24卷 1125-1133页

作者： M.L. Saucedo-Munoz A. Ortiz-Mariscal V.M. Lopez-Hirata J.D. Villegas-Cardenas orlando Soriano-Vargas Erika O. Avila-Davila Instituto Politecnico Nacional (ESIQIE) Apdo. Postal 118-395 Mexico D.F. 07300 Universidad Politecnica Metepec y Tultitlan Edo. Mex. Mexico Tecnológico de Estudios Superiores de Jocotitlan Jocotitlan Edo. Mex. Mexico

As-cast HK40 steel was aged at 700, 800, or 900℃ for times as long as 2000 h. Microstructural characterization showed that the primary M_7C_3 carbide network contained a substantial content of manganese, in agreement with the microsegregation of manganese calculated by Thermo-Calc using the Scheil–Gulliver module. The dissolution of primary carbides caused the solute supersaturation of austenite and subsequent precipitation of fine M_(23)C_6 carbides in the austenite matrix for aged specimens. During prolonged aging, the carbide size increased with increasing time because of the coarsening process. A time–temperature–precipitation diagram for M_(23)C_6 carbides was calculated using the Thermo-CalcPRISMA software; this diagram showed good agreement with the experimental growth kinetics of precipitation. The fine carbide precipitation caused an increase in hardness; however, the coarsening process of carbides promoted a decrease in hardness. Nanoindentation tests of the austenite matrix indicated an increase in ductility with increasing aging time.

关键词： as-cast HK40 steel carbide precipitation aging precipitation simulation

The interface of SiO_2/ZnS films studied by high resolution X-ray photoluminescence

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Theoretical & Applied Mechanics Letters 2018年第1期8卷 24-27页

作者： Shinjita Acharya orlando Trejo Anup Dadlani Jan Torgersen Filippo Berto Fritz Prinz Department of Mechanical Engineering Stanford University Department of Chemistry Stanford University Department of Mechanical and Industrial Engineering Norwegian University of Science and Technology Department of Materials Science and Engineering Stanford University

Sharp interfaces in optoelectronic devices are key for proper band alignment. Despite its benefits as buffer layer, ZnS deposited via atomic layer deposition(ALD) renders intermixed interfaces to its substrate, which can be detrimental for device performance. Here, we are attempting to elucidate the chemical species deriving from this metal-oxide to metal-sulfide transition studying ultrathin film ZnS on SiO_2 using high resolution X-ray photoluminescence spectroscopy(XPS).Regarding the S 2p spectra after a deposition of only three cycles of ZnS, we discover the many different chemical species in which S is present. These include intermediate oxides such as SO_4^(2-).These species become more obvious as we tilt the sample in the XPS chamber to shallower *** the Si 2p and S 2p high resolution peaks in the depth profile, one can clearly uncover the confinement of SO_4^(2-) to the interface of the underlying substrate. This may indicate that SiO_2/ZnS interfaces contain interfacial sulphates that likely alter the electronic configuration of this interface.

关键词： Atomic Layer Deposition Metal-Sulfide Zinc Sulfide Interface High resolution X-ray photoluminescence spectroscopy

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补偿凸变换与半凸函数的几何奇点提取

中国科学：数学 2016年第5期46卷 747-768页

作者：张克威 CROOKS Elaine orlando Antonio School of Mathematical Sciences University of Nottingham Department of Mathematics Swansea University FACET Universidad Nacional de Tucumn

补偿凸上变换和下变换是对给定函数作"紧贴"逼近的单参数单向变换.本文将它们应用到R^n中局部具有一般模的半凸/半凹函数和DC-函数(即两个凸函数的差函数)的奇点提取.(局部)半凹函数最常见的几何例子有Euclid距离函数和平方Euclid距离函... 详细信息

补偿凸上变换和下变换是对给定函数作"紧贴"逼近的单参数单向变换.本文将它们应用到R^n中局部具有一般模的半凸/半凹函数和DC-函数(即两个凸函数的差函数)的奇点提取.(局部)半凹函数最常见的几何例子有Euclid距离函数和平方Euclid距离函数.对于局部具有一般模的半凸函数f,本文证明在局部意义下,x是f的奇点(即不可微点)当且仅当它是f的1-阶"谷点",因而用本文的方法可以从具有一般模的局部半凸函数中提取所有的这些精细的几何奇点.更确切地讲,如果f是局部具有一般模的半凸函数,则"局部的"1-阶"山谷"变换在每个点x的极限存在,而且有显式表示lim_(λ→+∞)λV_λ(f)(x)=r_x^2/4,其中Vλ(f)(x)是f在x点的"山谷"变换,rx是f在x点次微分?-f(x)的最小包含球面的半径.所以,极限函数V∞(f)(x):=lim_(λ→+∞)λV_λ(f)(x)=r_x^2/4提供了一个半凸函数奇点1-阶"谷点"的"景观函数".同时,它也提供了补偿上凸变换Cuλ(f)(x)当λ→+∞时的一阶渐近展开式.对于具有局部线性模的局部半凸函数,本文进一步证明,补偿凸上变换的梯度当λ→+∞时的极限lim_(λ→+∞)▽C_λ~u(f)(x)存在,并且这个极限等于次微分?-f(x)的最小包含球面的中心.对于DC-函数f=g-h,本文证明它的1-阶"边缘"变换,当λ→+∞时满足lim inf_(λ→+∞)λE_λ(f)(x)(r_(g,x)-r_(h,x))~2/4,其中r_(g,x)和r_(h,x)分别是次微分?-g(x)和?-h(x)的最小包含球面的半径.

关键词：补偿凸变换山峰变换山谷变换半凸函数半凹函数奇点提取最小包含球面局部逼近

基于AHP-LP的铁矿石供应商选择方法研究

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基于AHP-LP的铁矿石供应商选择方法研究

作者： orlando GISWASWA 北京交通大学

学位级别：硕士

合理选择供应商是保证企业物资供应链顺畅运转的核心决策问题之一。当前研究主要采取“构建评价指标体系,提出多指标评价方法”的技术路径,其本质是建立在科学评价指标体系上供应商评估,缺少供应商评估的后续决策。本文认为供应商选择... 详细信息

合理选择供应商是保证企业物资供应链顺畅运转的核心决策问题之一。当前研究主要采取“构建评价指标体系,提出多指标评价方法”的技术路径,其本质是建立在科学评价指标体系上供应商评估,缺少供应商评估的后续决策。本文认为供应商选择应包括“供应商评估”(确定合作对象)和“订单分配”(确定合作规模)两个层次的内涵,故首先构建包含定性、定量因素的铁矿石供应商评价指标体系,使用层次分析法(AHP)生成每个供应商的总得分,形成供应商排名表。然后,考虑供应商的能力,质量和需求等约束条件构建线性规划模型(LP)确定给与不同供应商的订货规模。本文使用Gisande trading ltd公司数据进行算例分析,公司管理人员认为结果具有较高的可实施性,该方法有望改善公司供应商管理现状。

关键词：层次分析法线性规划供应商选择

Escherichia coli challenge and one type of smectite alter intestinal barrier of pigs

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Journal of Animal Science and Biotechnology 2014年第2期5卷 173-180页

作者： Juliana Abranches Soares Almeida Yanhong Liu Minho Song Jeong Jae Lee H Rex Gaskins Carol Wolfgang Maddox orlando Osuna James Eugene Pettigrew Department of Animal Sciences University of IllinoisUrbana 61801USA Department of Animal Science and Biotechnology Chungnam National UniversityDaejeonSouth Korea Department of Pathobiology University of IllinoisUrbana 61801 USA Milwhite Inc.BrownsvilleTXUSA

An experiment was conducted to determine how an E. coil challenge and dietary clays affect the intestinal barrier of pigs. Two groups of 32 pigs （initial BW： 6.9 ± 1.0 kg） were distributed in a 2 x 4 factorial arrangement of a randomized complete block design （2 challenge treatments： sham or E. coil, and 4 dietary treatments： control, 0.3% smectite A, 0.3% smectite B and 0.3% zeolite）, with 8 replicates total. Diarrhea score, growth performance, goblet cell size and number, bacterial translocation from intestinal lumen to lymph nodes, intestinal morphology, and relative amounts of sulfo and sialo mucins were measured. The E. coli challenge reduced performance, increased goblet cell size and number in the ileum, increased bacterial translocation from the intestinal lumen to the lymph nodes, and increased ileal crypt depth. One of the clays （smectite A） tended to increase goblet cell size in ileum, which may indicate enhanced protection. In conclusion, E. coli infection degrades intestinal barrier integrity but smectite A may enhance it.

关键词： Barrier function E.coli Pigs Smectite Zeolite

Hybrid low salinity water and surfactant process for enhancing heavy oil recovery

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Petroleum Exploration and Development 2023年第6期50卷 1466-1477页

作者： ROLDÁN-CARRILLO Teresa CASTORENA-CORTES Gladys SALAZAR CASTILLO Rodrigo orlando HERNÁNDEZ-ESCOBEDO Luis OLGUÍN-LORA Patricia GACHUZ-MURO Herón Instituto Mexicano del Petróleo Mexico City 07730Mexico Petroleos Mexicanos PEMEXVillahermosaMexico

Combining low salinity water (LSW) with surfactants has an enormous potential for enhancing oil recovery processes. However, there is no consensus about the mechanisms involved, in addition to the fact that several studies have been conducted in model systems, while experiments with rocks and reservoir fluids are scarce. This study presents a core-flooding experiment of LSW injection, with and without surfactant, using the core and heavy oil samples obtained from a sandstone reservoir in southeastern Mexico. The effluents and the crude oil obtained at each stage were analyzed. The study was complemented by tomographic analysis. The results revealed that LSW injection and hybrid process with surfactants obtained an increase of 11.4 percentage points in recovery factor. Various phenomena were caused by LSW flooding, such as changes in wettability and pH, ion exchange, mineral dissolution, detachment of fines and modification of the hydrocarbon profile. In the surfactant flooding, the reduction of interfacial tension and alteration of wettability were the main mechanisms involved. The findings of this work also showed that the conditions believed to be necessary for enhanced oil recovery with LSW, such as the presence of kaolinite or high acid number oil, are not relevant.

关键词： low salinity water flooding surfactant flooding hybrid processes enhanced oil recovery tomography

Interferometer Based on a D-shape Chaotic Optical Fiber for Measurement of Multiparameters

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Photonic Sensors 2012年第4期2卷 381-384页

作者： Susana SILVA Luis COELHO Philippe ROY orlando FRAZAO INESC Porto Rua do Campo Alegre 687 4169-007 Porto Portugal and Dept. de Fisica e Astronomia da Faculdade de Ciencias da Universiclacle do Porto Rua do Campo Alegre 687 4169-007 Porto Portugal Xlim UMR 6172 CNRS-University of Limoges 123 Avenue Albert Thomas 87060 Limoges Cedex France

An interferometer based on a D-shape chaotic optical tiber tor measurement ot multiparameters was proposed. The sensing structure relied on a D-shape fiber section spliced in between two singlemode fibers and interrogated in transmission. The optical spectrum was composed by multiple interference loss peaks, which were sensitive to the refractive index, temperature and strain-maximum sensitivities of 95.2 nm/RIU, 10.5 pm/℃ and -3.51 pm/με, respectively, could be achieved.

关键词： Optical fiber sensors interferometer chaotic fiber

Clinical and prognostic implications of delirium in elderly patients with non–ST-segment elevation acute coronary syndromes

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Journal of Geriatric Cardiology 2019年第2期16卷 121-128页

作者： Miquel Vives-Borras Manuel Martinez-Selles Albert ariza-Sole Maria T.Vidan Francesc Formiga Hector Bueno Juan Sanchis Oriol Alegre Albert Duran-Cambra Ramon Lopez-Palop Emad Abu-Assi Alessandro Sionis LONGEVO-SCA Investigators Department of Cardiology Hospital de la Santa Creu i Sant PauInstitute of Biomedical Research I1B Sant PauCIBERCVUniversitat Autonoma de BarcelonaBarcelonaSpain department of Cardiology Hospital General Universitario Gregorio MarahonC1BERCVUniversidad ComplutenseUniversidad EuropeaMadridSpain Hospital Universitari de Bellvitge L'Hospitalet de LlobregatBarcelonaSpain Hospital General Universitario Gregorio Maranon IiSGMCIBERFESUniversidad ComplutenseMadrid.Spain Hospital Doce de Octubre Centro Nacional de Investigaciones CardiovascularesMadridSpain Hospital Clinico de Valencia INCLIVAUniversidad de ValenciaCIBERCVSpain Hospital Universitario San Juan AlicanteSpain Hospital Alvaro Cunqueiro VigoSpain 不详

Background Elderly patients with non-ST-segment elevation acute coronary syndromes(NSTE-ACS)may present delirium but its clinical relevance is *** study aimed at detennining the clinical associated factors,and prognostic implications of delirium in old-aged patients admitted for *** LONGEVO-SCA is a prospective multicenter registry including unselected patients with NSTE-ACS aged>80 *** variables and a complete geriatric evaluation were assessed during *** association between delirium and 6-month mortality was assessed by a Cox regression model weighted for a propensity score including the potential confounding *** also analysed its association with 6-month bleeding and cognitive or functional *** Among 527 patients included,thirty-seven(7%)patients presented delirium during the *** was more frequent in patients with dementia or depression and in those from nursing homes(27.0%vs.3.1%,24.3%vs.11.6%,and 11.1%V5.2.2%,respectively;all P<0.05).Delirium was significantly associated with in-hospital infections(27.0%vs.5.3%,P<0.001)and usage of diuretics(70.3%vs.49.8%,P=0.02).Patients with delirium had longer hospitalizations[median 8.5(5.5-14)vs.6.0(4.0-10)days,P=0.02]and higher incidence of 6-month bleeding and mortality(32.3%vs.10.0%and 24.3%vs.10.8%,respectively;both P<0.05)but similar cognitive or functional *** was independently associated with 6-month mortality(HR=1.47,95%CI:1.02-2.13,P=0.04)and 6-month bleeding events(OR=2.87;95%CI:1.98-4」6,P<0.01).Conclusions In-hospital delirium in elderly patients with NSTE-ACS is associated with some preventable risk factors and it is an independent predictor of 6-month mortality.

关键词： Acute coronary syndromes Delirium Prognosis The elderly