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Aero.o. jet printing o. surface aco.stic wave micro.luidic devices

Micro.ystems & Nano.ngineering 2024年第1期10卷 231-242页

作者： jo.eph Rich Brian Co.e Teng Li Brando. Lu Hanyu Fu Brittany N.Smith jianping Xia Shujie Yang Ruo.u Zho.g james L.Do.erty Kanji kaneko Hiro.ki Suzuki Zhenhua Tian Aaro. D.Franklin To.y jun Huang Department o. Bio.edical Engineering Duke UniversityDurhamNC 27708USA Department o. Electrical and Co.puter Engineering Duke UniversityDurhamNC 27708USA Department o. Mechanical Engineering Virginia Polytechnic Institute and State UniversityBlacksburgVA 24061USA Tho.as Lo.d Department o. Mechanical Engineering and Materials Science Duke UniversityDurhamNC 27708USA Deptartment o. Precisio. Mechanics Faculty of Science and EngineeringChuo UniversityTokyo 112-8551Japan Department o. Chemistry Duke UniversityDurhamNC 27708USA

The additio. o. surface aco.stic wave(SAW)techno.o.ies to.micro.luidics has greatly advanced lab-o.-a-chip applicatio.s due to.their unique and po.erful attributes,including high-precisio. manipulatio.,versatility,integrability,bio.o.patibility,co.tactless nature,and rapid ***,the develo.ment o. SAW micro.luidic devices is limited by co.plex and time-co.suming micro.nano.abricatio. techniques and access to.cleanro.m facilities fo. multistep pho.o.itho.raphy and vacuum-based *** simplify the fabricatio. o. SAW micro.luidic devices with custo.izable dimensio.s and functio.s,we utilized the additive manufacturing technique o. aero.o. jet *** successfully fabricated custo.ized SAW micro.luidic devices o. varying materials,including silver nano.ires,graphene,and po.y(3,4-ethylenedio.ythio.hene)po.ystyrene sulfo.ate(PEDo.:PSS).To.characterize and co.pare the aco.stic actuatio. perfo.mance o. these aero.o. jet printed SAW micro.luidic devices with their cleanro.m-fabricated co.nterparts,the wave displacements and reso.ant frequencies o. the different fabricated devices were directly measured thro.gh scanning laser Do.pler ***,to.exhibit the capability o. the aero.o. jet printed devices fo. lab-o.-a-chip applicatio.s,we successfully co.ducted aco.stic streaming and particle co.centratio. ***,we demo.strated a no.el so.utio.-based,direct-write,single-step,cleanro.m-free additive manufacturing technique to.rapidly develo. SAW micro.luidic devices that sho.s viability fo. applicatio.s in the fields o. bio.o.y,chemistry,engineering,and medicine.

关键词： printing wave fluid

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Review o. Diverto. Studies in LHD

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Plasma Science and Techno.o.y 2006年第1期8卷 14-18页

作者： T. Mo.ISAKI S. MASUZAKI A. Ko.o.I N. o.YABU M. Ko.AYASHI j. miyazawa M. SHo.I 高翔 K. IDA K. IKEDA o. kaneko K. KAWAHATA S. KUBo.S. Mo.ITA K. NAGAo.A H. NAKANISHI K. NARIHARA Y. o.A M. o.AKABE B. j. PETERSo. S. SAKAKIBARA R. SAKAMo.o.T. SHIMo.UMA Y. TAKEIRI K. TANAKA K. To., K. TSUMo.I K. Y. WATABABE T. WATARI H. YAMADA I. YAMADA 严龙文杨青巍杨愚 Y.Yo.HIMURA M. Yo.HINUMA o. Mo.o.IMA Natio.al Institute fo. Fusio. Science Toki Gifu 509-5292 Japan Institute o. Plasma Physics Chinese Academy of Sciences Hefei 230031 China So.thwesteru Institute o. Physics Chengdu 610041 China

In the Large Helical Device （LHD）, two.different diverto. co.figuratio.s, i.e. helical diverto. （HD） and lo.al island diverto. （LID）, are utilized to.co.tro. the edge plasma. The HD with two.X-po.nts is an intrinsic diverto. fo. helio.ro. devices, acco.panied with a relatively thick ergo.ic layer o.tside the co.finement regio.. Edge and diverto. plasma behavio. fro. lo. density to.high density regimes is presented, referring to.the diverto. detachment. The effect o. the ergo.ic layer o. the edge transpo.t is also.discussed. o. the o.her hand, the LID is an advanced diverto. co.cept which realizes a high pumping efficiency by the co.binatio. o. an externally induced magnetic island and a clo.ed pumping system. Experimental results to.co.firm the fundamental diverto. perfo.mance o. the LID are presented.

关键词： LHD diverto. ergo.ic layer magnetic island edge plasma

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T1ρ/T2 mapping and histo.atho.o.y o. degenerative cartilage in advanced knee o.teo.rthritis

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Wo.ld jo.rnal o. o.tho.edics 2017年第4期8卷 350-356页

作者： Benjamin S Kester Philip M Carpenter Ho. j Yu Taiki No.aki Yasuhito.kaneko Hiro.hi Yo.hio.a Ran Schwarzko.f Divisio. o. Adult Reco.structio. Department of OrthopaedicsNYU Langone Medical Center Hospital for Joint Diseases Department o. Patho.o.y University of California IrvineOrange Department o. Radio.o.ical Sciences University of California IrvineOrange

AIM To.investigate whether no.mal thickness cartilage in o.teo.rthritic knees demo.strate depletio. o. pro.eo.lycan o. co.lagen co.tent co.pared to.healthy *** Magnetic reso.ance(MR) images were acquired fro.5 subjects scheduled fo. to.al knee arthro.lasty(TKA)(mean age 70 years) and 20 yo.ng healthy co.tro. subjects witho.t knee pain(mean age 28.9 years). MR images o. T1ρ mapping, T2 mapping, and fat suppressed pro.o.-density weighted sequences were *** TKA each co.dyle was divided into.4 parts(distal medial, po.terio. medial, distal lateral, po.terio. lateral) fo. cartilage analysis. Twenty specimens(bo.e and cartilage blo.ks) were examined. Fo. each jo.nt,the degree and extent o. cartilage destructio. was determined using the o.teo.rthritis Research So.iety Internatio.al cartilage histo.atho.o.y assessment *** magnetic reso.ance imaging(MRI) analysis, 2 readers perfo.med cartilage segmentatio. fo. T1ρ/T2 values and cartilage thickness *** Eleven areas in MRI including no.mal o. near no.mal cartilage thickness were selected. The co.respo.ding histo.atho.o.ical sectio.s demo.strated mild to.mo.erate o.teo.rthritis(o.). There was no.significant difference in cartilage thickness in MRI between co.tro. and advanced o. samples [medial distal co.dyle, P = 0.461;medial po.terio. co.dyle(MPC), P = 0.352; lateral distal co.dyle, P = 0.654; lateral po.terio. co.dyle, P = 0.550],suggesting arthritic specimens were mo.pho.o.ically similar to.no.mal o. early staged degenerative *** T2 and T1ρ values fro. the MPC were significantly higher amo.g the patients with advanced o.(P= 0.043). Fo. remaining co.dylar samples there was no.statistical difference in T2 and T1ρ values between cases and co.tro.s but there was a trend to.ards higher values in advanced o. patients. Co.CLUSIo. Tho.gh cartilage is mo.pho.o.ically no.mal o. near no.mal, degenerative changes exist in advanced o. patients. These changes can be detected w

关键词： T1rho o.teo.rthritis Magnetic reso.ance imaging Cartilage Knee

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ICRF Heated Lo.g-Pulse Plasma Discharges in LHD

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Plasma Science and Techno.o.y 2006年第1期8卷 28-32页

作者： R. KUMAZAWA T. SEKI T. MUTo. K. SAITo.T. WATARI Y. NAKAMURA M. SAKAMo.o.T. WATANABE S. KUBo.T. SHIMo.UMA Y. Yo.HIMURA H. IGAMI Y. TAKEIRI Y. o.A K. TSUMo.I M. o.AKABE K. IKEDA K. NAGAo.A o. kaneko.j. miyazawa S. Mo.ITA K. NARIHARA M. SHo.I S. MASUZAKI M. Go.o.T. Mo.ISAKI B. j. PETERSo. K. SATo.T. To.UZAWA N. ASHIKAWA K. NISHIMURA H. FUNABA H. CHIKARAISHI T. No.AKE Y. To.II H. o.ADA M. ICHIMURA H. HIGAKI Y. TAKASE H. KASAHARA F. SHIMPo.G.No.URA C.TAKAHASHI M.Yo.o.A A. KATo.赵燕平 j. S. Yo.N j. G. KWAK H. YAMADA K. KAWAHATA N. o.YABU K. IDA Y. NAGAYAMA N. No.A A. Ko.o.I S. SUDo.o. Mo.o.IMA Natio.al Institute fo. Fusio. Science Toki Japan Kyusyu University Kasuga Japan Nago.a University Faculty of Engineering Nagoya Japan Kyo.o.University Institute of Advanced Energy Uji Japan Tsukuba University Plasma Research Center Tsukuba Japan To.yo.University Graduate School of Frontier Sciences Tokyo Japan Institute o. Plasma Physics Chinese Academy of Sciences Hefei 230031 China KAERI 150 Deogjin-dong Yuseong-gu Daejeon Korea Rep.

A lo.g-pulse plasma discharge fo. mo.e than 30 min. was achieved o. the Large Helical Device （LHD）. A plasma o. ne = 0.8 × 10^19 m^-3 and T10 = 2.0 keV was sustained with PICH = 0.52 MW, PECH = 0.1 MW and averaged PNBI = 0.067 MW. To.al injected heating energy was 1.3 G j, which was a quarter o. the prepared RF heating energy. o.e o. the keys to.the success o. the experiment was a dispersio. o. the lo.al plasma heat lo.d to.diverto.s, acco.plished by shifting the magnetic axis inward and o.tward.

关键词： helical/stellarato. co.figuratio. ICRF heating steady state o.eratio.

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A new appro.ch to.transfect NF-κB deco. o.igo.eo.ynucleo.ides into.the perio.o.tal tissue using the ultraso.nd-micro.ubble metho.

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Internatio.al jo.rnal o. o.al Science 2017年第2期9卷 80-86页

作者： Hiro.uki Yamaguchi Yuji Ishida jun Ho.o.ichi jun-ichi Suzuki Risa Usumi-Fujita Yasuhiro.Shimizu Sawa kaneko Takashi o.o Department o. o.tho.o.tic Science Graduate School of Medical and Dental SciencesTokyo Medical and Dental UniversityTokyoJapan Department o. Advanced Clinical Science and Therapeutics Graduate School of MedicineThe University of TokyoTokyoJapan

The o.jective o. this study is to.investigate the effect o. the ultraso.nd-micro.ubble technique in nuclear facto. kappa B(NF-κB) deco. o.igo.eo.ynucleo.ide(o.N) transfectio. in the gingival tissue in mice. The 6-FAM-labeled scrambled deco. o.N with micro.ubbles was applied to.the perio.o.tal tissue in 8-week-o.d male C57BL/6j mice by ultraso.nd radiatio. at lo.(LUM-Sc) and high(HUM-Sc) intensities to.o.timize the transfectio. co.ditio. o. the ultraso.nd-micro.ubble *** inspectio.s were perfo.med two.ho.rs after transfectio. to.co.pare the expressio. with that in the sham-o.erated gro.p witho.t ultraso.nd radiatio.(A-Sc). Then, an NF-κB deco. was transfected into.the perio.o.tal tissue using the highintensity ultraso.nd-micro.ubble(HUM-NF) technique to.examine the anti-inflammato.y effects o. the deco. o.N. Western blo. analysis was perfo.med to.investigate the expressio. o. interleukin(IL)-1β, IL-6 and intercellular adhesio. mo.ecule-1(ICAM-1)in the gingival tissues in the HUM-Sc, the HUM-NF and co.tro. gro.ps. The fluo.escence micro.co.y results sho.ed that the fluo.escent intensity in the perio.o.tal tissues in the LUM-Sc and HUM-Sc gro.ps was significantly higher than that in the A-Sc and the co.tro. gro.ps. The fluo.escent intensity in the HUM-Sc gro.p, especially in the gingival co.nective tissue,was the highest o. all gro.ps. Western blo. analysis indicated that the pro.ein expressio. levels o. IL-1β, IL-6 and ICAM-1 in the HUM-NF gro.p were significantly lo.er than tho.e in the HUM-Sc and the co.tro. gro.ps. These findings suggest that the high-intensity ultraso.nd-micro.ubble technique is an effective to.l fo. deco. transfectio. into.the perio.o.tal tissue.

关键词： deco. o.igo.eo.ynucleo.ide gene therapy perio.o.tal tissue ultraso.nd

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活性炭纤维对No.2的吸附

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新型炭材料 1990年第3期6卷 75-76,68页

作者： K.kaneko.j.Imai 陈玉琴

No.No.2是典型的大气污染物;作为被吸附物,它们具有不同的性质。No.临界温度为180K,在室温下处于超临界状态;而No.2是一种可凝气体,因它的沸点为294K,且具有二聚作用。因此,只有极少数微孔固体才对No.效吸附。分散的过渡金属氧化物... 详细信息

No.No.2是典型的大气污染物;作为被吸附物,它们具有不同的性质。No.临界温度为180K,在室温下处于超临界状态;而No.2是一种可凝气体,因它的沸点为294K,且具有二聚作用。因此,只有极少数微孔固体才对No.效吸附。分散的过渡金属氧化物的活性炭纤维(ACF)利用微孔填充的化学吸附能吸附大量的No.在氧化铁为分散体时。

关键词：活性炭纤维二氧化氮吸附

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Challenges and Po.sibilities o. Cell-Based Tissue-Engineered Vascular Grafts

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Cybo.g and Bio.ic Systems 2021年第1期2021卷 16-31页

作者： junichi Saito.Mako.o.kaneko Yo.hihiro.Ishikawa Utako.Yo.o.ama Department o. Physio.o.y Tokyo Medical UniversityShinjuku-kuTokyoJapan Cardio.ascular Research Institute Yokohama City UniversityYokohamaKanagawaJapan Faculty o. Science and Techno.o.y Meijo UniversityNagoyaAichiJapan

There is urgent demand fo. bio.o.ically co.patible vascular grafts fo. bo.h adult and pediatric *** utility o. co.ventio.al no.bio.egradable materials is limited because o. their thro.bo.enicity and inability to.gro.,while auto.o.o.s vascular grafts invo.ve co.siderable disadvantages,including the invasive pro.edures required to.o.tain these healthy vessels fro. patients and insufficient availability in patients with systemic *** o. these issues co.ld be o.erco.e by tissue-engineered vascular grafts(TEVGs).A large bo.y o. evidence has recently emerged in suppo.t o. TEVG techno.o.ies,intro.ucing diverse cell so.rces(e.g.,so.atic cells and stem cells)and no.el fabricatio. metho.s(e.g.,scaffo.d-guided and self-assembled appro.ches).Befo.e TEVG can be applied in a clinical setting,ho.ever,several aspects o. the techno.o.y must be impro.ed,such as the feasibility o. o.taining cells,their bio.o.patibility and mechanical pro.erties,and the time needed fo. fabricatio.,while the safety o. supplemented materials,the patency and no.thro.bo.enicity o. TEVGs,their gro.th po.ential,and the lo.g-term influence o. implanted TEVGs in the bo.y must be *** recent advances in TEVG fabricatio. have yielded pro.ising results,mo.e research is needed to.achieve the mo.t feasible metho.s fo. generating o.timal *** article reviews multiple aspects o. TEVG fabricatio.,including mechanical requirements,extracellular matrix co.po.ents,cell so.rces,and tissue engineering *** po.ential o. perio.ic hydro.tatic pressurizatio. in the pro.uctio. o. scaffo.d-free TEVGs with o.timal elasticity and stiffness is also.*** the future,the integratio. o. multiple techno.o.ies is expected to.enable impro.ed TEVG perfo.mance.

关键词： o.timal Engine elasticity

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Identificatio. o. telo.ere maintenance gene variatio.s related to.lung adeno.arcino.a risk by geno.e-wide asso.iatio. and who.e geno.e sequencing analyses

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Cancer Co.municatio.s 2024年第2期44卷 287-293页

作者： Ko.ya Shiraishi Atsushi Takahashi Yukihide Mo.o.awa Yataro.Daigo.Syuzo.kaneko Takahisa Kawaguchi Hideo.Kunito. Shingo.Matsumo.o.Hidehito.Ho.ino.chi Akiteru Go.o.Takayuki Ho.da Kimihiro.Shimizu Masahiro.To.asawa Daisuke Takayanagi Mo.o.o.u Saito.Akira Saito.Yuichiro.o.e Shun-ichi Watanabe Ko.chi Go.o.Masahiro.Tsubo. Katsuya Tsuchihara Sadaaki Takata To.o.i Ao. Atsushi Takano.Masashi Ko.ayashi Yo.ei Miyagi Kazumi Tanaka Hiro.uki Suzuki Daichi Maeda Takumi Yamaura Maiko.Matsuda Yo.o.Shimada Takaaki Mizuno.Hiro.i Sakamo.o.Teruhiko.Yo.hida Yasushi Go.o.Tatsuya Yo.hida Taiki Yamaji Mako.o.So.o.e Shinichi To.o.ka Kazue Yo.eda Katsuhiro.Masago.Fumihiro.Tanaka Megumi Hara No.uo.Fuse Sato.hi S.Nishizuka No.iko.Mo.o. No.ie Sawada Yuichiro.Nishida Kazuki Kumada Kenji Takeuchi Ko.o.Tanno.Yasushi Yatabe Kuniko.Sunami To.o.uki Hishida Yasunari Miyazaki Hidemi Ito.Mitsuhiro.Amemiya Hiro.iko.To.suka Haruhiko.Nakayama To.o.uki Yo.o.e Kazuyo.hi Ishigaki To.hiteru Nagashima Yo.chi o.taki Kazuhiro.Imai Ken Takasawa Yo.hihiro.Minamiya Kazuma Ko.ayashi Kenichi o.ubo.Kenji Wakai Atsushi Shimizu Masayuki Yamamo.o.Mo.o.i Iwasaki Ko.chi Matsuda jo.ji Inazawa Yuichi Shiraishi Hiro.o.hi Nishikawa Yo.hino.i Murakami Michiaki Kubo.Fumihiko.Matsuda Yo.chiro.Kamatani Ryuji Hamamo.o.Keitaro.Matsuo.Takashi Ko.no Divisio. o. Geno.e Bio.o.y National Cancer Center Research InstituteTokyoJapan Department o. Clinical Geno.ics National Cancer Center Research InstituteTokyoJapan Labo.ato.y fo. Statistical Analysis Center for Integrative Medical SciencesRIKENYokohamaJapan Department o. Geno.ic Medicine Research InstituteNational Cerebral and Cardiovascular CenterOsakaJapan Labo.ato.y fo. Geno.yping Develo.ment Center for Integrative Medical SciencesRIKENYokohamaJapan Center fo. Antibo.y and Vaccine Therapy Research HospitalInstitute of Medical ScienceThe University of TokyoTokyoJapan Department o. Medical o.co.o.y and Cancer Center and Center for Advanced Medicine against CancerShiga University of Medical ScienceOtsuJapan Divisio. o. Medical AI Research and Develo.ment National Cancer Center Research InstituteTokyoJapan Center fo. Geno.ic Medicine Graduate School of MedicineKyoto UniversityKyotoJapan Department o. Medical o.co.o.y Japanese Red Cross Medical CenterTokyoJapan Department o. Tho.acic o.co.o.y National Cancer Center Hospital EastJapan Department o. Tho.acic o.co.o.y National Cancer Center HospitalTokyoJapan Department o. Cellular and o.gan Patho.o.y Graduate School of MedicineAkita UniversityAkitaJapan Department o. Respirato.y Medicine Tokyo Medical and Dental UniversityBunkyo-kuTokyoJapan Divisio. o. General Tho.acic Surgery Department of SurgeryShinshu University School of MedicineMatsumotoNaganoJapan Department o. General Surgical Science Division of General Thoracic SurgeryGunma University Graduate School of MedicineIntegrative Center of General SurgeryGunma University HospitalGunmaJapan Department o. Gastro.ntestinal Tract Surgery Fukushima Medical University School of MedicineFukushimaJapan StaGen Co. LtdTokyoJapan Divisio. o. Tho.acic Surgery National Cancer Center HospitalTokyoJapan Department o. Tho.acic Surgery National Cancer Center Hospital EastChibaJapan Divisio. o. Translatio.al Info.matics Exploratory Oncology Research and Clinical Trial Center(EPOC

Dear edito.,Lung carcino.a is respo.sible fo. the highest fatal-ity rate amo.g cancer-related deaths glo.ally,with lung adeno.arcino.a(LADC)emerging as the prevailing sub-type.

关键词： adeno.arcino.a lung Lung

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Maximum Likeliho.d Metho. fo. RFID Tag Set Cardinality Estimatio. using Multiple Independent Reader Sessio.s

Maximum Likelihood Method for RFID Tag Set Cardinality Estim...

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2011年亚太信号与信息处理协会年会

作者： Chuyen T. NGUYEN Kazuno.i HAYASHI Megumi kaneko Petar Po.o.SKI Hideaki SAKAI Department o. Electro.ic Systems Aalborg University Aalborg Denmark

In this paper, Radio.Frequency IDentificatio. （RFID） tag set cardinality estimatio. pro.lem is co.sidered under the mo.el o. multiple independent reader sessio.s with unreliable radio.co.municatio. links in which transmissio. erro.s might o.cur. After the R-th reader sessio., the number o. tags detected in j （j = 1, 2, ..., R） reader sessio.s is updated, which we call o.served evidence. Then, in o.der to.maximize the likeliho.d functio. o. the number o. tags and the transmissio. erro. pro.ability given the o.served evidences, we pro.o.e three different estimatio. metho.s depending o. ho. to.treat the discrete nature o. tag set cardinality. Co.puter simulatio. results demo.strate the effectiveness o. the pro.o.ed metho..

关键词： Radio.o.municatio. Likeliho.d Functio.s base number Statistical analysis RFID tags so.idificatio. Set (Psycho.o.y) Transmissio. erro.s TAGGING maximum likeliho.d

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AZ31镁合金板的可成形性、力学性能和组织研究

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锻造与冲压 2007年第5期 48-51页

作者： E. Yukutake j. kaneko 张绍平(译) 黄金(译) 段磊(译) 田明聪(译) 胡亚民(校) Graduate scho.l o. Industrial Techno.o.y Nihon University Japan Co.lege o. Industrial Techno.o.y Nihon University Japan 不详重庆工学院材料科学与工程学院

因为轧制了的镁板及其合金具有稳定的结晶组织，所以它们都有很明显的塑性各向异性，也就是具有高的兰克福值即R值（板拉力试样宽厚方向应变比）。主要原因是在室温下，镁的滑移系主要是在密排六方晶格的基面内。因此．用同样方法轧制... 详细信息

因为轧制了的镁板及其合金具有稳定的结晶组织，所以它们都有很明显的塑性各向异性，也就是具有高的兰克福值即R值（板拉力试样宽厚方向应变比）。主要原因是在室温下，镁的滑移系主要是在密排六方晶格的基面内。因此．用同样方法轧制较厚的基面结构时，基面与薄板平面保持平行。所以用塑性变形减少薄板厚度非常困难．室温下可成形性很差。在拉伸、扭转、弯曲的情况下．它们显示出很差的可成形性。

关键词：可成形性 AZ31镁合金板结晶组织力学性能塑性各向异性六方晶格塑性变形

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