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Biogenic synthesis of silver nanoparticles using Persicaria odorata leaf extract: Antibacterial, cytocompatibility, and in vitro wound healing evaluation

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Particuology 2022年第11期70卷 10-19页

作者： Faridah Aminullah Lubis Nik Ahmad Nizam NikMalek nor suriani sani Khairunadwa Jemon Department of Biosciences Faculty of ScienceUniversiti Teknologi Malaysia81310 UTMSkudaiJohorMalaysia Centre for Sustainable Nanomaterials(CSNano) Ibnu Sina Institute for Scientific and Industrial Research(ISI-ISIR)Universiti Teknologi Malaysia81310 UTMSkudaiJohorMalaysia Office of Deputy Vice Chancellor(Research and Innovation) Universiti Teknologi Malaysia81310 UTMSkudaiJohorMalaysia

Biogenic synthesis of silver nanoparticles(b-AgNPs)utilising plant extract has gained the interest of researchers due to the environmentally friendly and cost-effective ***,the extent of its application in the biomedical field remains *** study evaluates the antibacterial,cytocompatibility,and wound healing activities of synthesised AgNPs using Persicaria odorata leaves extract(PO-AgNPs).The formation of PO-AgNPs was observed by visual colour changes and verified by ultraviolet-visible(UV–vis)spectrophotometer,which revealed a surface plasmon resonance(SPR)at around 440 nm,and further confirmed by X-ray diffraction(XRD).Characterisation using Fourier transform infrared(FTIR)spectroscopy showed biomolecules from the leaves extract presented together on *** emission scanning electron microscope(FESEM)and high-resolution transmission electron microscopy(HR-TEM)images revealed PO-AgNPs nanospheres with diameters of 11±3 *** diffusion test(DDT)and minimum inhibitory concentration(MIC)analysis resulted in a dose-dependent inhibition of PO-AgNPs against tested Staphylococcus epidermidis and Methicillin-resistant Staphylococcus aureus(MRSA).These results were further corroborated by time-kill kinetic assay which revealed that PO-AgNPs were bactericidal against both strains 24 h *** and in vitro wound healing evaluation against normal human fibroblast cells,HSF 1184 inferred that PO-AgNPs are non-toxic to normal cells and able to enhance cell migration as compared to the non-treated ***,PO-AgNPs are biocompatible and possess antibacterial and wound healing capabilities that are useful in biomedical applications.

关键词： Silver nanoparticles Biosynthesis Antibacterial Cytocompatibility Wound healing

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In situ biosynthesized silver nanoparticle-incorporated synthesized zeolite A using Orthosiphon aristatus extract for in vitro antibacterial wound healing

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Particuology 2022年第8期20卷 27-34页

作者： Muhammad Hariz Asraf nor suriani sani Craig Denver Williams Khairunadwa Jemon Nik Ahmad Nizam Nik Maliek Department of Biosciences Faculty of ScienceUniversiti Teknologi Malaysia81310 SkudaiJohorMalaysia Office of Deputy Vice Chancellor(Research and Innovation) Universiti Teknologi Malaysia81310 UTM SkudaiJohorMalaysia University of Wolverhampton Wulfuna StreetWolverhampton WV11SBEnglandUK Centre for Sustainable Nanomaterials(CSNano) Ibnu Sina Institute for Scientific and Industrial Research(ISI-SIR).Universiti Teknologi Malaysia81310 SkudaiJohorMalaysia

The capability of synthesized zeolite A(SZ)to immobilize Ag ions(Ag-SZ)and Ag nanoparticles(AgNp-SZ)were comparatively studied.A novel approach of in situ biosynthesized AgNP-incorporated synthesized zeolite A(AgNp-SZ)was synthesized at an optimum volume of 0.4mL of the Orthosiphon aristatus(***)leaves plant extract(5%)using an in situ *** comparison,Ag-Sz was produced by loading the synthesized zeolite with Ag *** synthesized materials were characterized for their morphologies and *** characterization analysesvalidate thathe biosynthesized AgNP(<100 nm)using *** leaves extract was incorporated into the zeolite *** antibacterial testing confirmed that these materials have antibacterial activity against Escherichia coliATCC11229 and Staphylococcus aureus ATCC ***/MBC analysis demonstrated that in 0.9%saline solution,AgNP-SZ had higher antibacterial activity than *** in vitro cell viability and migration assays were further examined towards human skin fibroblast cells HSF *** show that the materials are not cytotoxicto HSF1184,and the biosynthesized AgNP-SZ promotes cell migration and proliferation higher than *** research proved that the biocompatible antibacterial wound healing agent of AgNP-SZ can be synthesized using an in situ approach where the reduction process of Ag ions in the zeolite Acan be performed using plant extract.

关键词： Zeolite Orthosiphon aristatus Biosynthesis Silver nanoparticles Antibacterial In vitro wound healing

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Antibacterial, cytotoxicity and wound healing assessments of amine-functionalised zeolite Y

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Particuology 2019年第4期17卷 116-123页

作者： Muhammad Hariz Asraf Nik Ahmad Nizam Nik Malek Khairunadwa Jemon nor suriani sani Mustapha Salisu Muhammad Department of Biosciences Faculty of Science Universiti Teknologi Malaysia 81310 Skudai Johor Malaysia Centre for Sustainable Nanomaterials (CSNano) Ibnu Sina Institute for Scientific and Industrial Research (IS1-ISIR) Universiti Teknologi Malaysia 81310 UTMJohor Malaysia Office of Deputy Vice Chancellor (Research and Innovation) Universiti Teknologi Malaysia 81310 UTM Skudai Johor Malaysia

The antibacterial activities,cytotoxicity,and wound healing of amine(3-aminopropyltriethoxysilane (APTES))-functionalised zeolite Y against normal human fibroblast cells were *** characterisation of unmodified and amine-functionalised zeolites Y (Z,ZA 0.04,ZA 0.4,and ZA 0.6) by Fourier transform infrared spectroscopy,X-ray powder diffraction,and energy dispersive X-ray analysis proved that the APTES molecules were grafted onto the zeolite Y surface without distorting its framework *** amine-functionalised zeolite Y samples possessed antibacterial activities against several ATCC bacteria that were correlated with the increased amount of APTES on the zeolite Y ***,when a higher concentration of APTES was grafted on the zeolite Y,higher cytotoxicity was observed against the fibroblast *** the ZA 0.6 sample (zeolite Y functionalised with 0.6 M of APTES) had higher antibacterial activity,it was cytotoxic to the ***,the selection of an antibacterial agent for human treatment purposes must also consider its cytotoxicity effect against human cells to ensure it is biocompatible.

关键词： Zeolite Y Amine functionalised zeolite Functionalisation Antibacterial agent Cytotoxicity

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Optimization of Sentiment Analysis Using Teaching-Learning Based Algorithm

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Computers, Materials & Continua 2021年第11期69卷 1783-1799页

作者： Abdullah Muhammad Salwani Abdullah nor Samsiah sani Center for Artificial Intelligence Technology Faculty of Information Science&TechnologyUniversiti KebangsaanKajang43000Malaysia

Feature selection and sentiment analysis are two common studies that are currently being conducted;consistent with the advancements in computing and growing the use of social *** dimensional or large feature sets is a key issue in sentiment analysis as it can decrease the accuracy of sentiment classification and make it difficult to obtain the optimal subset of the ***,most reviews from social media carry a lot of noise and irrelevant ***,this study proposes a new text-feature selection method that uses a combination of rough set theory(RST)and teaching-learning based optimization(TLBO),which is known as *** framework to develop the proposed RSTLBO includes numerous stages:(1)acquiring the standard datasets(user reviews of six major ***)which are used to validate search result feature selection methods,(2)preprocessing of the dataset using text processing *** involves applying text processing methods from natural language processing techniques,combined with linguistic processing techniques to produce high classification results,(3)employing the RSTLBO method,and(4)using the selected features from the previous process for sentiment classification using the Support Vector Machine(SVM)*** show an improvement in sentiment analysis when combining natural language processing with linguistic processing for text *** importantly,the proposed RSTLBO feature selection algorithm is able to produce an improved sentiment analysis.

关键词： Feature selection sentiment analysis rough set theory teachinglearning optimization algorithms text processing

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A Sparse Optimization Approach for Beyond 5G mmWave Massive MIMO Networks

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Computers, Materials & Continua 2022年第8期72卷 2797-2810页

作者： Waleed Shahjehan Abid Ullah Syed Waqar Shah Imran Khan nor Samsiah sani Ki-Il Kim Department of Electrical Engineering University of Engineering and Technology PeshawarPakistan Center for Artificial Intelligence Technology Faculty of Information Science&TechnologyUniversiti KebangsaanKajang43000Malaysia Department of Computer Science and Engineering Chungnam National UniversityDaejeon34134Korea

Millimeter-Wave(mmWave)Massive MIMO is one of the most effective technology for the fifth-generation(5G)wireless *** improves both the spectral and energy efficiency by utilizing the 30–300 GHz millimeter-wave bandwidth and a large number of antennas at the base ***,increasing the number of antennas requires a large number of radio frequency(RF)chains which results in high power *** order to reduce the RF chain’s energy,cost and provide desirable quality-ofservice(QoS)to the subscribers,this paper proposes an energy-efficient hybrid precoding algorithm formm Wave massive MIMO networks based on the idea of RF chains *** sparse digital precoding problem is generated by utilizing the analog precoding ***,it is jointly solved through iterative fractional programming and successive convex optimization(SCA)*** results show that the proposed scheme outperforms the existing schemes and effectively improves the system performance under different operating conditions.

关键词： 5G mmwave precoding massive mimo complexity

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An Optimal Framework for SDN Based on Deep Neural Network

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Computers, Materials & Continua 2022年第10期73卷 1125-1140页

作者： Abdallah Abdallah Mohamad Khairi Ishak nor Samsiah sani Imran Khan Fahad RAlbogamy Hirofumi Amano Samih M.Mostafa Department of Industrial Engineering School of Applied Technical Sciences German Jordanian UniversityAmman35247Jordan School of Electrical and Electronic Engineering Universiti Sains MalaysiaNibong Tebal14300Malaysia Center for Artificial Intelligence Technology Faculty of Information Science and TechnologyThe National University of Malaysia(UKM)Bangi43600SelangorMalaysia Department of Electrical Engineering University of Engineering and TechnologyPeshawar814Pakistan Turabah University College Computer Sciences ProgramTaif UniversityTaif21944Saudi Arabia Research Institute for Information Technology Kyushu UniversityFukuoka819-0395Japan Computer Science-Mathematics Department Faculty of ScienceSouth Valley UniversityQena83523Egypt

Software-defined networking(SDN)is a new paradigm that promises to change by breaking vertical integration,decoupling network control logic from the underlying routers and switches,promoting(logical)network control centralization,and introducing network ***,the controller is similarly vulnerable to a“single point of failure”,an attacker can execute a distributed denial of service(DDoS)attack that invalidates the controller and compromises the network security in *** address the problem of DDoS traffic detection in SDN,a novel detection approach based on information entropy and deep neural network(DNN)is *** approach contains a DNN-based DDoS traffic detection module and an information-based entropy initial inspection *** initial inspection module detects the suspicious network traffic by computing the information entropy value of the data packet’s source and destination Internet Protocol(IP)addresses,and then identifies it using the DDoS detection module based on *** assaults were found when suspected irregular traffic was *** reveal that the algorithm recognizes DDoS activity at a rate of more than 99%,with a much better accuracy *** false alarm rate(FAR)is much lower than that of the information entropy-based detection ***,the proposed framework can shorten the detection time and improve the resource utilization efficiency.

关键词： Deep neural network computer networks data security optimization

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Microbial populations,sensory,and volatile compounds profling of local cooked rice

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Food Quality and Safety 2024年第2期8卷 334-345页

作者： Nur-Shahera Mohammad Sabri nor Ainy Mahyudin Muhammad Shirwan Abdullah sani Ming Gan Han Kah Hui Chong Kousalya Padmanabhan Jiang Shan nor Khaizura Mahmud Ab Rashid Department of Food Science Faculty of Food Science and TechnologyUniversiti Putra MalaysiaSerdangSelangorMalaysia Department of Food Service and Management Faculty of Food Science and TechnologyUniversiti Putra MalaysiaSelangorMalaysia International Institute for Halal Research and Training International Islamic University Malaysia(IIUM)Kuala LumpurMalaysia Department of Biological Sciences Sunway UniversityBandar SunwayMalaysia Laboratory of Food Safety and Food Integrity Institute of Tropical Agriculture and Food SecurityUniversiti Putra MalaysiaSerdangSelangorMalaysia

Objectives:This study is designed to investigate the microbial populations,sensory,and volatile compounds profling of locally cooked rice stored at room temperature(30°C)on days 0,1,2,and 3(D0,D1,D2,and D3)for the determination of specifc spoilage organisms(SSOs).Materials and Methods:Microbiological,physicochemical,sensory evaluation,and volatile organic compounds(VOCs)analyses were conducted for samples of cooked rice stored at room temperature on days 0,1,2,and *** of cooked rice was then identifed by linking present organisms with the changes occurring throughout the storage ***:Microbiological analysis revealed the presence of spore-forming bacteria,yeast,and moulds,which survived the cooking *** total viable count exceeded the microbiological limit at 6.90 log CFU/g on D3,panellists deemed cooked rice unacceptable for consumption on D2 at a total sensory score of 11.00,which indicates that D2 was the day cooked rice *** culture-dependent and cultureindependent methods,Bacillus cereus was identifed as the sole bacteria observed throughout the storage period,confrming that the bacteria were *** VOC analysis proposed several metabolites,3-eicosene,1-heptadecene,hexacosane,phenol,4,4ʹ-(1-methylethylidene)bis-,n-nonadecanol-1,and cyclohexanone,as potential spoilage markers of cooked ***:*** is confrmed to be the SSO of cooked rice,in which spoilage occured after 48 h of storage at room *** organoleptic rejection in cooked rice was shown to be linked to the production of various compounds by *** which could be proposed as potential spoilage markers for cooked rice.

关键词： Cooked rice room temperature specifc spoilage organisms(SSOs) B.cereus sensory analysis volatile organic compounds(VOCs)

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Epithelial Layer Estimation Using Curvatures and Textural Features for Dysplastic Tissue Detection

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Computers, Materials & Continua 2021年第4期67卷 761-777页

作者： Afzan Adam Abdul Hadi Abd Rahman nor Samsiah sani Zaid Abdi Alkareem Alyessari Nur Jumaadzan Zaleha Mamat Basela Hasan Faculty of Information Science and Technology Center for Artificial Intelligence TechnologyUniversiti Kebangsaan MalaysiaBangiSelangor43300Malaysia Faculty of Science and Technology School of Mathematical SciencesUniversiti Kebangsaan MalaysiaBangiSelangor43300Malaysia Department of Information Technology and Computing Faculty of Computer StudiesArab Open UniversityAmmanJordan

Boundary effect in digital pathology is a phenomenon where the tissue shapes of biopsy samples get distorted during the sampling *** morphological pattern of an epithelial layer is greatly ***,the shape deformation model can normalise the distortions,but it needs a 2D *** theory,on the other hand,is not yet tested on digital pathology ***,this work proposed a curvature detection to reduce the boundary effects and estimates the epithelial *** boundary effect on the tissue surfaces is normalised using the frequency of a curve deviates from being a straight *** epithelial layer’s depth is estimated from the tissue edges and the connected nucleolus ***,the textural and spatial features along the estimated layer are used for dysplastic tissue *** proposed method achieved better performance compared to the whole tissue regions in terms of detecting dysplastic *** result shows a leap of kappa points from fair to a substantial agreement with the expert’s ground truth *** improved results demonstrate that curvatures have been effective in reducing the boundary effects on the epithelial layer of ***,quantifying and classifying the morphological patterns for dysplasia can be *** textural and spatial features on the detected epithelial layer can capture the changes in tissue.

关键词： Digital pathology grading dysplasia tissue boundary effect

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MEC-IoT-Healthcare: Analysis and Prospects

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Computers, Materials & Continua 2023年第6期75卷 6219-6250页

作者： Hongyuan Wang Mohammed Dauwed Imran Khan nor Samsiah sani Hasmila Amirah Omar Hirofumi Amano Samih M.Mostafa College of Computer Science Guangdong University of Science and TechnologyDongGuan523083China Department of Medical Instrumentation Techniques Engineering Dijlah University CollegeBaghdadIraq Department of Electrical Engineering University of Engineering&TechnologyPeshawar814Pakistan Center for Artificial Intelligence Technology Faculty of Information Science and TechnologyUniversiti Kebangsaan Malaysia43600BangiSelangorMalaysia Research Institute for Information Technology Kyushu UniversityFukuoka819-0395Japan Computer Science-Mathematics Department Faculty of ScienceSouth Valley UniversityQena83523Egypt

Physical sensors,intelligent sensors,and output recommenda-tions are all examples of smart health technology that can be used to monitor patients’health and change their *** health is an Internet-of-Things(IoT)-aware network and sensing infrastructure that provides real-time,intelligent,and ubiquitous healthcare *** of the rapid development of cloud computing,as well as related technologies such as fog computing,smart health research is progressively moving in the right ***,fog computing,IoT sensors,blockchain,privacy and security,and other related technologies have been the focus of smart health research in recent *** the moment,the focus in cloud and smart health research is on how to use the cloud to solve the problem of enormous health data and enhance service performance,including cloud storage,retrieval,and calculation of health big *** article reviews state-of-the-art edge computing methods that has shifted to the collection,transmission,and calculation of health data,which includes various sensors and wearable devices used to collect health data,various wireless sensor technologies,and how to process health data and improve edge performance,among other ***,the typical smart health application cases,blockchain’s application in smart health,and related privacy and security issues were reviewed,as well as future difficulties and potential for smart health *** comparative analysis provides a reference for the the mobile edge computing in healthcare systems.

关键词： IoT mobile-edge computing cloud computing e-health

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Physicochemical Analysis of Selected Durian Hybrids at Bukit Tangga, Kedah, Malaysia

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Journal of Agricultural Science and Technology(B) 2012年第12期2卷 1262-1267页

作者： Mohd Asrul sani Bahari Mohd Masaruddin nor Hanis Aifaa Yusoff Horticulture Research Centre Malaysian Agricultural Research and Development Institute Bukit Tangga Kedah Malaysia

The physicochemical analysis was carried out to quantify the total soluble solids, acidity, pH, ascorbic acid contents and pulp colour of eight selected durian hybrid clones. The aim of this study was to select the most promising durian hybrids for commercialization. The durian hybrid fruits were collected in an established durian research plot. All tested characteristics with the exception for total soluble solids （TSS） showed significant differences （P 〈 0.05） amongst the eight durian hybrids with four check cultivars. F1 hybrid 15-3 had significantly higher pH （7.25） and lower titratable acidity （0.09%） than other hybrids. While for ascorbic acid content, durian hybrid 7-3 （26.13 rag/100 g） showed significantly higher than other hybrids. As for pulp colour, hybrids 1-15, 1-17 and 7-20 were yellowish orange/deep yellow. Even though there was no significant differences for TSS, three durian hybrids showed value above 39.00 °Brix and there were hybrid 14-3 （39.97 °Brix）, hybrid 8-16 （39.83 °Brix） and hybrid 7-3 （39.50 °Brix）. Based on the results of this study, Fl hybrids durian 1-15, 7-3, 8-16, 14-3 and 15-3 shall become successful candidates for recommendation to farmers for commercial production in Malaysia. However, further evaluations on fruit eating quality and stability of the hybrids should be completed prior to recommendation for commercialization.

关键词： Durio zibethinus Murr. physicochemical analysis durian hybrids.

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