Antibacterial, cytotoxicity and wound healing assessments of amine-functionalised zeolite Y
作者机构：Department of Biosciences Faculty of Science Universiti Teknologi Malaysia 81310 Skudai Johor Malaysia Centre for Sustainable Nanomaterials (CSNano) Ibnu Sina Institute for Scientific and Industrial Research (IS1-ISIR) Universiti Teknologi Malaysia 81310 UTMJohor Malaysia Office of Deputy Vice Chancellor (Research and Innovation) Universiti Teknologi Malaysia 81310 UTM Skudai Johor Malaysia
出 版 物：《Particuology》 (颗粒学报（英文版）)
年 卷 期：2019年第17卷第4期
页 面：116-123页
核心收录：
学科分类：0817[工学-化学工程与技术] 08[工学] 0805[工学-材料科学与工程（可授工学、理学学位）] 0703[理学-化学] 0702[理学-物理学] 0801[工学-力学（可授工学、理学学位）]
基 金：from the Faculty of Biosciences and Medical Engineering (FBME) UTM and Ministry of Higher Education Malaysia
主 题：Zeolite Y Amine functionalised zeolite Functionalisation Antibacterial agent Cytotoxicity
摘 要：The antibacterial activities,cytotoxicity,and wound healing of amine(3-aminopropyltriethoxysilane (APTES))-functionalised zeolite Y against normal human fibroblast cells were *** characterisation of unmodified and amine-functionalised zeolites Y (Z,ZA 0.04,ZA 0.4,and ZA 0.6) by Fourier transform infrared spectroscopy,X-ray powder diffraction,and energy dispersive X-ray analysis proved that the APTES molecules were grafted onto the zeolite Y surface without distorting its framework *** amine-functionalised zeolite Y samples possessed antibacterial activities against several ATCC bacteria that were correlated with the increased amount of APTES on the zeolite Y ***,when a higher concentration of APTES was grafted on the zeolite Y,higher cytotoxicity was observed against the fibroblast *** the ZA 0.6 sample (zeolite Y functionalised with 0.6 M of APTES) had higher antibacterial activity,it was cytotoxic to the ***,the selection of an antibacterial agent for human treatment purposes must also consider its cytotoxicity effect against human cells to ensure it is biocompatible.
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