In situ biosynthesized silver nanoparticle-incorporated synthesized zeolite A using Orthosiphon aristatus extract for in vitro antibacterial wound healing
作者机构：Department of BiosciencesFaculty of ScienceUniversiti Teknologi Malaysia81310 SkudaiJohorMalaysia Office of Deputy Vice Chancellor(Research and Innovation)Universiti Teknologi Malaysia81310 UTM SkudaiJohorMalaysia University of WolverhamptonWulfuna StreetWolverhampton WV11SBEnglandUK Centre for Sustainable Nanomaterials(CSNano)Ibnu Sina Institute for Scientific and Industrial Research(ISI-SIR).Universiti Teknologi Malaysia81310 SkudaiJohorMalaysia
出 版 物：《Particuology》 (颗粒学报（英文版）)
年 卷 期：2022年第20卷第8期
页 面：27-34页
核心收录：
学科分类：081704[工学-应用化学] 07[理学] 0817[工学-化学工程与技术] 070304[理学-物理化学(含∶化学物理)] 08[工学] 0805[工学-材料科学与工程（可授工学、理学学位）] 0703[理学-化学] 0702[理学-物理学]
主 题：Zeolite Orthosiphon aristatus Biosynthesis Silver nanoparticles Antibacterial In vitro wound healing
摘 要：The capability of synthesized zeolite A(SZ)to immobilize Ag ions(Ag-SZ)and Ag nanoparticles(AgNp-SZ)were comparatively studied.A novel approach of in situ biosynthesized AgNP-incorporated synthesized zeolite A(AgNp-SZ)was synthesized at an optimum volume of 0.4mL of the Orthosiphon aristatus(***)leaves plant extract(5%)using an in situ *** comparison,Ag-Sz was produced by loading the synthesized zeolite with Ag *** synthesized materials were characterized for their morphologies and *** characterization analysesvalidate thathe biosynthesized AgNP(100 nm)using *** leaves extract was incorporated into the zeolite *** antibacterial testing confirmed that these materials have antibacterial activity against Escherichia coliATCC11229 and Staphylococcus aureus ATCC ***/MBC analysis demonstrated that in 0.9%saline solution,AgNP-SZ had higher antibacterial activity than *** in vitro cell viability and migration assays were further examined towards human skin fibroblast cells HSF *** show that the materials are not cytotoxicto HSF1184,and the biosynthesized AgNP-SZ promotes cell migration and proliferation higher than *** research proved that the biocompatible antibacterial wound healing agent of AgNP-SZ can be synthesized using an in situ approach where the reduction process of Ag ions in the zeolite Acan be performed using plant extract.
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