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EUV/Soft X-Ray Multilayer Optics

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EUV/Soft X-Ray Multilayer Optics

Multidrug-Resistant of Escherichia coli and Salmonella spp. Strains in Chicken Feces Intended for Consumption in Open Spaces of Ouagadougou, Burkina Faso

Photonics Asia 2004;Optoelectronics,Microelectronics,and Nanotech

作者： Sergiy Yulin Torsten Feigl nicolas benoit Norbert Kaiser Fraunhofer-Institut für Angewandte Optik und Feinmechanik Albert-Einstein-Str. 7 07745 Jena Germany Fraunhofer-Institut für Angewandte Optik und Feinmechanik Albert-Einstein-Str. 7 07745 Jena Germany Fraunhofer-Institut für Angewandte Optik und Feinmechanik Albert-Einstein-Str. 7 07745 Jena Germany Fraunhofer-Institut für Angewandte Optik und Feinmechanik Albert-Einstein-Str. 7 07745 Jena Germany

Most applications of Mo/Si multilayer optics in Extreme ultraviolet lithography (EUVL) require a high normal incidence reflectivity. Using dc magnetron sputtering we achieved R = 68.8 % @ λ = 13.45 nm

关键词： EUV, Mo/Si, barrier layers, interface-engineered mirrors, thermal stability, broadband mirror, narrowband mirror, laterally graded coatings.

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Open Journal of Applied Sciences 2024年第4期14卷 881-892页

作者： Stéphanie Lynseh Carine Sita Bénao Dabiré Amana Métuor Abdoul Karim Ouattara Rahimatou Yasmine Wendkouni Tiemtoré nicolas Ouédraogo Blandine Ouédraogo Rhaina Olivia Badini Lionel Eliada benoit Bambara Serge Sougué Jacques Simporé Biomolecular and Genetic Laboratory (LABIOGENE) Pietro Annigoni Biomolecular Research Center (CERBA) Department of Biochemistry-Microbiology University Joseph Ki-Zerbo Ouagadougou Burkina Faso Department of Biochemistry-Microbiology University of D&#233dougou D&#233dougou Burkina Faso National Malaria Research and Training Centre (CNRFP) Ouagadougou Burkina Faso

Resistant bacteria can be transmitted to humans through feces or contaminated meat from local chickens. Bacterial strains were isolated from the intestinal contents of 400 local chicken samples from various sales sites. These strains were then characterized using bacteriological and biochemical methods to identify resistant strains. In a study conducted in Ouagadougou, we systematically collected chicken fecal samples from 20 locations across the city, followed by isolation and identification of Salmonella spp. using specific enrichment and culture methods, as well as Escherichia coli. Bacterial strains were characterized using antibiotic resistance profiles were determined through agar diffusion tests, revealing sensitivity or resistance to a range of antibiotics based on established scientific criteria. The results showed that out of the 400 samples collected, 81.25% and 63.5% were contaminated by Escherichia coli and Salmonella spp., respectively. Among these, 86.15% of identified Escherichia coli and 50.78% of Salmonella spp. displayed resistance to at least one tested antibiotic. Among 280 Escherichia coli isolates identified resistant to at least one antibiotic, 31.07% were resistant to cefotaxime (CTX), 20.35% to ceftazidime (CAZ), 21.07% to ceftriaxone (CTR), 75% to amoxicillin clavulanic acid (AMC), 23.57% aztreoname (ATM) and 27.14% were resistant to imipenem (IMP). In the case of the 129 Salmonella spp. isolates resistant to at least one tested antibiotic, 34.88% were resistant to CTX;41.08% to CAZ;35.65% to CTR, 92% to AMC, 39.53% to ATM and finally 47.28% were resistant to IMP. Our study revealed high prevalence of resistance in bacterial strains isolated from local chickens sold outdoors in Ouagadougou. These findings raise significant public health concerns, due to the possible transmission of these resistant strains to humans through the consumption of contaminated meat, thus complicating the treatment of bacterial infections.

关键词： Multidrug-Resistant Chicken Ouagadougou Escherichia coli Salmonella spp. Antibiotic

Prospective study comparing hepatic steatosis assessment by magnetic resonance imaging and four ultrasound methods in 105 successive patients

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World Journal of Gastroenterology 2023年第22期29卷 3548-3560页

作者： Remi Collin benoit Magnin Constance Gaillard Carine nicolas Armand Abergel Benjamin Buchard Gastroenterology and Endoscopy Unit Dupuytren University HospitalLimoges 87000France Department of Hepatology and Gastroenterology Clermont-Ferrand University HospitalClermont-Ferrand 63000France Department of Radiology Clermont-Ferrand University HospitalClermont-Ferrand 63000France

BACKGROUND Non-alcoholic fatty liver disease(NAFLD)is becoming a major health problem,resulting in hepatic,metabolic and cardio-vascular *** To evaluate new ultrasonographic tools to detect and measure hepatic *** We prospectively included 105 patients referred to our liver unit for NAFLD suspicion or *** underwent ultrasonographic measurement of liver sound speed estimation(SSE)and attenuation coefficient(AC)using Aixplorer MACH 30(Supersonic Imagine,France),continuous controlled attenuation parameter(cCAP)using Fibroscan(Echosens,France)and standard liver ultrasound with hepato-renal index(HRI)*** steatosis was then classified according to magnetic resonance imaging proton density fat fraction(PDFF).Receiver operating curve(ROC)analysis was performed to evaluate the diagnostic performance in the diagnosis of *** Most patients were overweight or obese(90%)and had metabolic syndrome(70%).One third suffered from *** was identified in 85 patients(81%)according to ***-one patients(20%)had advanced liver ***,AC,cCAP and HRI correlated with PDFF,with respective Spearman correlation coefficient of-0.39,0.42,0.54 and 0.59(P<0.01).Area under the receiver operating characteristic curve(AUROC)for detection of steatosis with HRI was 0.91(0.83-0.99),with the best cut-off value being 1.3(Se=83%,Sp=98%).The optimal cCAP threshold of 275 dB/m,corresponding to the recent EASL-suggested threshold,had a sensitivity of 72%and a specificity of 80%.Corresponding AUROC was 0.79(0.66-0.92).The diagnostic accuracy of cCAP was more reliable when standard deviation was<15 dB/m with an AUC of 0.91(0.83-0.98).An AC threshold of 0.42 dB/cm/MHz had an AUROC was 0.82(0.70-0.93).SSE performed moderately with an AUROC of 0.73(0.62-0.84).CONCLUSION Among all ultrasonographic tools evaluated in this study,including new-generation tools such as cCAP and SSE,HRI had the best *** is also the simple

关键词： Non-alcoholic fatty liver disease Ultrasonography Steatosis assessment Magnetic resonance imaging Controlled attenuation parameter

Transversal Instability for the Thermodiffusive Reaction-Diffusion System

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Chinese Annals of Mathematics,Series B 2015年第5期36卷 871-882页

作者： Michal KOWALCZYK benoit PERTHAME nicolas VAUCHELET Departamento de Ingenieria Matematica and Centro de Modelamiento Matem'atico(UMI CNRS 2807) Universidad de Chile Sorbonne Universités UPMC Univ Paris 06UMR 7598Laboratoire Jacques-Louis LionsF-75005ParisFrance CNRS UMR 7598Laboratoire Jacques-Louis LionsF-75005ParisFrance INRIA-Paris-Rocquencourt EPC MAMBADomaine de VoluceauBP10578153 Le Chesnay CedexFrance

The propagation of unstable interfaces is at the origin of remarkable patterns that are observed in various areas of science as chemical reactions, phase transitions, and growth of bacterial colonies. Since a scalar equation generates usually stable waves, the simplest mathematical description relies on two-by-two reaction-diffusion systems. The authors' interest is the extension of the Fisher/KPP equation to a two-species reaction which represents reactant concentration and temperature when used for flame propagation,and bacterial population and nutrient concentration when used in *** authors study circumstances in which instabilities can occur and in particular the effect of dimension. It is observed numerically that spherical waves can be unstable depending on the coefficients. A simpler mathematical framework is to study transversal instability, which means a one-dimensional wave propagating in two space ***, explicit analytical formulas give explicitely the range of paramaters for instability.

关键词： Traveling waves Stability analysis Reaction-diffusion equation Thermodiffusive system

Composite Waves for a Cell Population System Modeling Tumor Growth and Invasion

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Chinese Annals of Mathematics,Series B 2013年第2期34卷 295-318页

作者： Min TANG nicolas VAUCHELET Ibrahim CHEDDAD Irene VIGNON-CLEMENTEL Dirk DRASDO benoit PERTHAME Department of mathematics Institute of Natural Sciences and MOE-LSCShanghai Jiao Tong University INRIA Paris Rocquencourt ParisFrance Laboratoire Jacques-Louis Lions UPMC Univ Paris 06 and CNRS UMR 7598F-75005ParisFrance

In the recent biomechanical theory of cancer growth,solid tumors are considered as liquid-like materials comprising elastic *** this fluid mechanical view,the expansion ability of a solid tumor into a host tissue is mainly driven by either the cell diffusion constant or the cell division rate,with the latter depending on the local cell density(contact inhibition) or/and on the mechanical stress in the *** the two by two degenerate parabolic/elliptic reaction-diffusion system that results from this modeling,the authors prove that there are always traveling waves above a minimal speed,and analyse their *** appear to be complex with composite shapes and *** small parameters allow for analytical solutions,and in particular,the incompressible cells limit is very singular and related to the Hele-Shaw *** singular traveling waves are recovered numerically.

关键词：反应扩散系统肿瘤生长细胞群合成波侵袭建模力学理论弹性元件

Nanovolcano microelectrode arrays: toward long- term on-demand registration of transmembrane action potentials by controlled electroporation

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Microsystems & Nanoengineering 2020年第1期6卷 578-589页

作者： benoit X.E.Desbiolles Etienne de Coulon nicolas Maino Arnaud Bertsch Stephan Rohr Philippe Renaud Laboratory of Microsystems LMIS4 Ecole Polytechnique Federale de LausanneLausanneSwitzerland Department of Physiology Laboratory of Cellular Optics IIUniversity of BernBernSwitzerland

Volcano-shaped microelectrodes(nanovolcanoes)functionalized with nanopatterned self-assembled monolayers have recently been demonstrated to report cardiomyocyte action potentials after gaining spontaneous intracellular *** nanovolcanoes exhibit recording characteristics similar to those of state-of-the-art micro-nanoelectrode arrays that use electroporation as an insertion *** this study,we investigated whether the use of electroporation improves the performance of nanovolcano arrays in terms of action potential amplitudes,recording durations,and *** with neonatal rat cardiomyocyte monolayers grown on nanovolcano arrays demonstrated that electroporation pulses with characteristics derived from analytical models increased the efficiency of nanovolcano recordings,as they enabled multiple on-demand registration of intracellular action potentials with amplitudes as high as 62 mV and parallel recordings in up to~76%of the available *** performance of nanovolcanoes showed no dependence on the presence of functionalized nanopatterns,indicating that the tip geometry itself is instrumental for establishing a tight seal at the cell–electrode interface,which ultimately determines the quality of ***,the use of electroporation permitted the recording of attenuated cardiomyocyte action potentials during consecutive days at identical sites,indicating that nanovolcano recordings are nondestructive and permit long-term on-demand recordings from excitable cardiac *** from demonstrating that less complex manufacturing processes can be used for next-generation nanovolcano arrays,the finding that the devices are suitable for performing on-demand recordings of electrical activity from multiple sites of excitable cardiac tissues over extended periods of time opens the possibility of using the devices not only in basic research but also in the context of comprehensive drug testing.

关键词： arrays recording action

Semen characteristics of the three genetic types of boars reared in Benin

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Asian pacific Journal of Reproduction 2021年第2期10卷 82-89页

作者： Ignace O.Dotché Aichatou Gakou Constant Boris O.B.Bankolé Mahamadou Dahouda Isidore Houaga nicolas Antoine-Moussiaux Jean Paul Dehoux Pierre Thilmant benoit G.Koutinhouin Issaka Youssao Abdou Karim Department of Animal Production and Health Laboratory of Animal Biotechnology and Meat TechnologyPolytechnic School of Abomey-CalaviUniversity of Abomey-Calavi01 BP 2009CotonouBenin Department of Animal Production Faculty of Agronomic ScienceUniversity of Abomey-Calavi01 BP 526CotonouBenin Research Unit"Vector-Borne Diseases and Biodiversity"(UMaVeB) Centre International de Recherche-Développement sur l’Elevage en zone Subhumide(CIRDES)Burkina Faso Fundamental and Applied Research for Animals and Health Faculty of Veterinary MedicineUniversity of LiègeVallée 2Avenue de Cureghem4000 LiègeBelgium Laboratory of Experimental Surgery Universite Catholique de Louvain55/70Avenue Hippocrate1200BrusselsBelgium Provincial Center of Productions Animales Liège(CPL Animal)Rue de Saint Remy5 B4601 ArgenteauBelgium

Objective:To characterize the semen of three genetic types of boars(local,improved and Large White)reared in ***:Semen of local,improved and Large White boars reared in Benin were collected using the gloved hand method and analyzed to determine volume,pH,concentration,mobility,motility,and *** effect of the genetic type of boar on semen characteristics was aslo ***:Duration of ejaculation and semen volume of Large White boar were significantly higher than those of local and improved boars(P<0.05).The semen of improved boars had a higher motility score than that of Large White and local boars(P<0.001).The semen of local boars was more concentrated in the spermatozoa than that of improved and Large White boars(P<0.05).The proportion of spermatozoa of improved boars with normal morphology(93.6%)was significantly higher than that of local(82.2%)and Large White boars(81.6%)(P<0.001).The proportion of spermatozoa with folded tails in the semen of Large White boars(9.2%)was significantly higher than that observed in improved(1.8%)and local(5.0%)boars(P<0.001).The proportion of spermatozoa with proximal cytoplasmic droplets in semen of improved boars(2.7%)was significantly lower than that in Large White(6.8%)and local(9.7%)boars(P<0.001).The local(1.5%)and Large White boars(1.1%)showed more spermatozoa with distal cytoplasmic droplets in their semen compared to the improved boars(0.4%).Conclusions:The semen characteristics of pigs reared in Benin vary from one genetic type to *** genetic type has a strong *** Large White boar produces larger semen,the local boar produces more concentrated semen and the improved boar produces spermatozoa that are morphologically *** semen of these three genetic types can be used in artificial insemination but the improved boar's semen is more recommended.

关键词： Boars Semen Local pigs Benin Semen characteristics Genetic types

Global Wheat Head Detection(GWHD)Dataset:A Large and Diverse Dataset of High-Resolution RGB-Labelled Images to Develop and Benchmark Wheat Head Detection Methods

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Plant Phenomics 2020年第1期2卷 243-254页

作者： Etienne David Simon Madec Pouria Sadeghi-Tehran Helge Aasen Bangyou Zheng Shouyang Liu Norbert Kirchgessner Goro Ishikawa Koichi Nagasawa Minhajul A.Badhon Curtis Pozniak benoit de Solan Andreas Hund Scott C.Chapman Frédéric Baret Ian Stavness Wei Guo Arvalis Institut du végétal3 Rue Joseph et Marie Hackin75116 ParisFrance UMR1114 EMMAH INRAECentre PACABâtiment ClimatDomaine Saint-Paul228 Route de l’AérodromeCS 4050984914 Avignon CedexFrance Plant Sciences Department Rothamsted ResearchHarpendenUK Institute of Agricultural Sciences ETH ZurichUniversitätstrasse 28092 ZurichSwitzerland CSIRO Agriculture and Food Queensland Biosciences Precinct306 Carmody RoadSt Lucia4067 QLDAustralia Plant Phenomics Research Center Nanjing Agricultural UniversityNanjingChina Institute of Crop Science National Agriculture and Food Research OrganizationJapan Hokkaido Agricultural Research Center National Agriculture and Food Research OrganizationJapan Department of Computer Science University of SaskatchewanCanada Department of Plant Sciences University of SaskatchewanCanada School of Food and Agricultural Sciences The University of QueenslandGatton4343 QLDAustralia Graduate School of Agricultural and Life Sciences The University of Tokyo1-1-1 Midori-choNishitokyo CityTokyoJapan

The detection of wheat heads in plant images is an important task for estimating pertinent wheat traits including head population density and head characteristics such as health,size,maturity stage,and the presence of *** studies have developed methods for wheat head detection from high-resolution RGB imagery based on machine learning ***,these methods have generally been calibrated and validated on limited *** variability in observational conditions,genotypic differences,development stages,and head orientation makes wheat head detection a challenge for computer ***,possible blurring due to motion or wind and overlap between heads for dense populations make this task even more *** a joint international collaborative effort,we have built a large,diverse,and well-labelled dataset of wheat images,called the Global Wheat Head Detection(GWHD)*** contains 4700 high-resolution RGB images and 190000 labelled wheat heads collected from several countries around the world at different growth stages with a wide range of *** for image acquisition,associating minimum metadata to respect FAIR principles,and consistent head labelling methods are proposed when developing new head detection *** GWHD dataset is publicly available at http://***/and aimed at developing and benchmarking methods for wheat head detection.

关键词： Wheat wheat maturity

加巴喷丁减轻颈浅丛神经阻滞下甲状腺切除术后的延迟性疼痛

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麻醉与镇痛 2010年第3期6卷 39-45页

作者： nicolas Brogly, MD Jean-Michel Wattier, MD Gregoire Andrieu, MD Daliana Peres, MD Emanuel Robin, MD, PhD Eric Kipnis, MD, PhD Laurent Arnalsteen, MD Beatrice Thielemans, DPharm Bruno CarnaiUe, MD, PhD Francois Pattou, MD, PhD benoit Vallet, MD, PhD Gilles Lebuffe, MD, PhD 李波(译) 舒化青(译) 姚尚龙(校) Department of Anesthesiology and Intensive Care-Section of Pain Department of Pharmacology Department of Endocrine and General Surgery Claude Huriez University Hospital rue Michel Polonovski 59037 Lille cedex France 不详

背景有研究证明手术前12服加巴喷丁可减轻手术后疼痛，然而加巴喷丁辅助用于区域麻醉和慢性疼痛的效果还不清楚。本研究选择颈浅丛神经阻滞（superficialcervicalplexusblock，SCPB）麻醉下行甲状腺切除术的患者，观察手术前口服加巴喷... 详细信息

背景有研究证明手术前12服加巴喷丁可减轻手术后疼痛，然而加巴喷丁辅助用于区域麻醉和慢性疼痛的效果还不清楚。本研究选择颈浅丛神经阻滞（superficialcervicalplexusblock，SCPB）麻醉下行甲状腺切除术的患者，观察手术前口服加巴喷丁对手术后早期和晚期（6个月之后）疼痛的作用。方法50例签署知情同意书的患者随机分成2组，即G组和P组，分别于手术前2小时口服1．2g加巴喷丁和安慰剂。通过数字量化评分（0—6分）评估手术前焦虑程度。患者于标准全麻诱导后行颈浅丛神经阻滞，分别记录手术中、手术后在麻醉恢复室和回到病房后患者的基本情况和镇痛药消耗量。数字量化评分（0—10分）评估手术后24小时静息时和吞咽时疼痛程度。如果静息时疼痛评分超过4分（最疼为10分），则每隔6小时静注1g扑热息痛或者50mg曲马多。手术前l天和甲状腺切除术后6个月，进行神经病理性疼痛诊断问卷。结果两组患者的一般资料、手术前焦虑程度评分、手术中用药、手术时间和手术后恢复室停留时间差异没有统计学意义。2组患者手术后24小时内镇痛药应用次数相似（G组：3[0—5]剂量／24小时；P组：3[1。5]剂量／24小时；P：NS）、静息时疼痛评分（G组：2，2『0．2。3．7]；P组：2[0—6．3]；P=NS）和吞咽时疼痛评分（G组：2．8[0．4～8．9]：P组：3[1．4。6．3]；P=NS）均没有差异。手术后6个月神经病理性疼痛诊断问卷评分超过3分者有8例，而手术前仅有2例（P=0．04）。延迟性神经病理性疼痛的8例患者中7例为单纯颈丛神经阻滞，仅有1例为手术前口服加巴喷丁辅助颈丛神经阻滞的患者（P=0．01）。结论手术前口服加巴喷丁没有改变颈丛神经阻滞下甲状腺切除术患者手术后的早期疼痛，但能预防手术后6个月出现的延迟性神经病理性疼痛。

关键词：颈浅丛神经阻滞甲状腺切除术手术后疼痛加巴喷丁切除术后延迟性神经病理性疼痛减轻