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Development and validation of a nomogram model for predicting the risk of gallstone recurrence after gallbladder-preserving surgery

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Hepatobiliary & Pancreatic Diseases International 2024年第3期23卷 288-292页

作者： Peng Liu yong-Wei chen Che Liu Yin-Tao Wu Wen-Chao Zhao Jian-yong Zhu Yang An nian-Xin Xia Faculty of Hepato-Pancreato-Biliary Surgery the First Medical CenterChinese PLA General HospitalBeijing 100853China Institute of Hepatobiliary Surgery of Chinese PLA Beijing 100853China Key Laboratory of Digital Hepetobiliary Surgery of Chinese PLA Beijing 100853China

Background:The high incidence of gallstone recurrence was a major concern for laparoscopic gallbladderpreserving *** study aimed to investigate the risk factors for gallstone recurrence after gallbladder-preserving surgery and to establish an individualized nomogram model to predict the risk of gallstone ***:The clinicopathological and follow-up data of 183 patients who were initially diagnosed with gallstones and treated with gallbladder-preserving surgery at our hospital from January 2012 to January 2019 were retrospectively *** independent predictive factors for gallstone recurrence following gallbladder-preserving surgery were identified by multivariate logistic regression analysis.A nomogram model for the prediction of gallstone recurrence was constructed based on the selected *** C-index,receiver operating characteristic(ROC)curve and calibration curve were used to evaluate the predictive power of the nomogram model for gallstone ***:During the follow-up period,a total of 65 patients experienced gallstone recurrence,and the recurrence rate was 35.5%.Multivariate logistic regression analysis revealed that the course of gallstones>2 years[odds ratio(OR)=2.567,95%confidence interval(CI):1.270-5.187,P=0.009],symptomatic gallstones(OR=2.589,95%CI:1.059-6.329,P=0.037),multiple gallstones(OR=2.436,95%CI:1.133-5.237,P=0.023),history of acute cholecystitis(OR=2.778,95%CI:1.178-6.549,P=0.020)and a greasy diet(OR=2.319,95%CI:1.186-4.535,P=0.014)were independent risk factors for gallstone recurrence after gallbladder-preserving surgery.A nomogram model for predicting the recurrence of gallstones was established based on the above five *** results showed that the C-index of the nomogram model was 0.692,suggesting it was valuable to predict gallstone ***,the calibration curve showed good consistency between the predicted probability and actual ***:The nomogram model for

关键词： Gallstone Gallbladder-preserving surgery Recurrence Risk factors Nomogram

Synthesis and modification of nanowires anchored on electrodes for electrochemical and electrophysical applications

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Nano Research 2024年第10期17卷 8863-8884页

作者： Feiyang Mo Zhitao chen nian Liu Xing Xie School of Civil and Environmental Engineering Georgia Institute of Technology311 Ferst Drive NWAtlantaGA 30332USA School of Chemical and Biomolecular Engineering Georgia Institute of Technology311 Ferst Drive NWAtlantaGA 30332USA

The integration of nanowires onto electrode surfaces marks a significant advancement over traditional electrode materials,conferring upon nanowire-modified electrodes a vast array of applications within electrochemical and electrophysical *** nanowires used for electrode modification can be catalogized into two distinct types:anchored nanowires and free-standing nanowires.A critical advantage of anchored nanowires lies in their enhanced electrical connectivity with the substrate,which reduces electrode resistance and facilitates charge ***,the anchorage of nanowires onto electrodes provides additional mechanical support,bolstering the structural stability of the nanowire ***,we review the development of anchored nanowires designed for applications in energy storage,electrocatalysis,and electric field treatment(EFT)over the past *** focus on the synthesis and modification strategies employed for anchored nanowires,culminating in the evaluation of these fabrication and enhancement *** this analysis,we aim to furnish comprehensive insights into the preparation of anchored nanowires,guiding the selection of appropriate fabrication processes and subsequent functional modifications.

关键词： electrode modification direct growth etching energy storage electrocatalysis electric field treatment

High-performance nickel metal hydride battery anode with enhanced durability and excellent low-temperature discharge capability

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Nano Research 2024年第10期17卷 8819-8825页

作者： Zhitao chen Huitian Liu Jean Nei nian Liu School of Chemical and Biomolecular Engineering Georgia Institute of TechnologyAtlantaGA 30332USA GP Batteries HongkongChina

Current AB_(5)-type hydrogen storage alloys employed in nickel-metal hydride(NiMH)batteries exhibit exceptional low-temperature discharge performance but suffer from limited cycle life and insufficient high-temperature *** overcome these challenges,we introduce a hydrothermal synthesized LaF_(3)coating layer on the surface of the AB_(5)anode *** LaF_(3)coating layer adds a protective barrier for the active material,significantly improving the battery's cycle life and high-temperature *** findings indicate that(1)the LaF_(3)coated anode demonstrates an extended cycle life with increased specific capacity and a capacity retention of 88%after 40 cycles of abusive overcharging and rapid discharging at room temperature.(2)The synthesized anode exhibits a 97%recovery of its specific capacity of 292.7 mAh/g following 144 h of high-temperature storage.(3)The low-temperature discharge capacity of the synthesized anode remains on par with the pristine AB_(5)alloy at 230.4 mAh/g in a-40℃*** research presents a significant advancement in hydrogen storage alloy coatings and offers valuable insights for designing electrodes in NiMH batteries.

关键词： nickel metal hydride(NiMH)batteries hydrothermal synthesis lanthanum fluoride discharge capacity low temperature

More than just aligning the teeth:Clear aligners with multifunctional prowess

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Nano Research 2024年第8期17卷 7665-7674页

作者： Yang chen Lei-Ming Cao nian-nian Zhong Zi-Zhan Li Lin-Lin Bu Fang-Yi Huo Hong He State Key Laboratory of Oral and Maxillofacial Reconstruction and Regeneration Key Laboratory of Oral Biomedicine Ministry of EducationHubei Key Laboratory of StomatologySchool and Hospital of StomatologyWuhan UniversityWuhan 430079China Department of Oral and Maxillofacial-Head Neck Oncology School and Hospital of StomatologyWuhan UniversityWuhan 430079China Department of Zhuankou Clinical Branches School and Hospital of StomatologyWuhan UniversityWuhan 430000China Department of Orthodontics School and Hospital of StomatologyWuhan UniversityWuhan 430079China

With the increasing demand for beauty and health,clear aligners(CAs)have been widely applied among patients with ***,patients treated with CAs also face some potential complications,such as demineralization,dental caries,and periodontal *** addition,some patients have additional needs to improve their quality of life,such as bleaching *** order to prevent or solve these problems,the modification of CAs is a promising method because their extensive long-term contact with tooth surfaces makes them ideal devices for implementing adjuvant medical *** this review,we discuss various advanced CAs with medical functions based on the clinical needs of *** far as we know,the additional functions of CAs mainly include antibacterial,remineralization,whitening,and accelerating tooth *** functions are achieved by two major pathways,the combination of CAs with drugs/biomaterials and increasing the capacity or affinity of *** addition,we discuss the current limitations of in vitro experiments which are designed to explore the effectiveness and properties of novel CAs,and the challenges of bringing a multifunctional appliance from proposal to clinical *** the end of this review,we provide insights into the broader prospects for the improvement of CAs.

关键词： advanced clear aligners medical device modification drug delivery system personalized medicine

Research on the influences of motion characteristics of jetting projectile charge under water

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Defence Technology（防务技术） 2024年第3期33卷 411-425页

作者： Xing chen yong-gang Lu Institute of Systems Engineering China Academy of Engineering PhysicsMianyang 621900SichuanChina

Shaped charge warhead is important for enhancing the damage performance of underwater *** paper used finite element analysis software and based on JPC water penetration experiments to examine the influence of liner parameters(wall thickness,material),charge aspect ratio,and stand-off distance on the movement characteristics of JPC in *** findings reveal that the head diameter of the JPC increases and experiences significant erosion after entering the water,the effective length of the JPC in water undergoes two distinct phases:a growth phase and a decrease phase,with the velocity of the JPC decaying *** the liner thickness,stand-off distance and the charge aspect ratio can improve the erosion resistance and the velocity retention capacity of the *** optimal ranges for liner thickness and stand-off distance are 0.0363D_(k) to 0.0545D_(k)(D_(k) is the charge diameter),the stand-off distance should be within 1.0D_(k).After the charge aspect ratio higher than 1.25,the charge structure exerts minimal influence the movement characteristics of the JPC in *** density plays a crucial role in the velocity decay pattern of the JPC during *** with higher densities exhibit superior velocity retention capabilities in water,with the velocity decay pattern converging if the densities are ***,copper,tantalum and tungsten liners are deemed appropriate for underwater shaped charge ***,the results will provide an important reference for the design of underwater shaped charge warhead.

关键词： JPC Movement characteristics Underwater penetration Numerical simulation

Gelatin-Based Metamaterial Hydrogel Films with High Conformality for Ultra-Soft Tissue Monitoring

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Nano-Micro Letters 2024年第2期16卷 347-364页

作者： Yuewei chen Yanyan Zhou Zihe Hu Weiying Lu Zhuang Li Ning Gao nian Liu Yuanrong Li Jing He Qing Gao Zhijian Xie Jiachun Li yong He State Key Laboratory of Fluid Power and Mechatronic Systems School of Mechanical EngineeringZhejiang UniversityHangzhou 310027People’s Republic of China School of Mechanical Engineering Guizhou UniversityGuiyang 550025People’s Republic of China Stomatology Hospital School of StomatologyZhejiang University School of MedicineClinical Research Center for Oral Diseases of Zhejiang ProvinceKey Laboratory of Oral Biomedical Research of Zhejiang ProvinceCancer Center of Zhejiang UniversityHangzhou 310006People’s Republic of China

Implantable hydrogel-based bioelectronics(IHB)can precisely monitor human health and diagnose ***,achieving biodegradability,biocompatibility,and high conformality with soft tissues poses significant challenges for *** is the most suitable candidate for IHB since it is a collagen hydrolysate and a substantial part of the extracellular matrix found naturally in most *** study used 3D printing ultrafine fiber networks with metamaterial design to embed into ultra-low elastic modulus hydrogel to create a novel gelatin-based conductive film(GCF)with mechanical *** regulation of GCF nearly covers soft tissue mechanics,an elastic modulus from 20 to 420 kPa,and a Poisson’s ratio from-0.25 to *** negative Poisson’s ratio promotes conformality with soft tissues to improve the efficiency of biological *** GCF can monitor heartbeat signals and respiratory rate by determining cardiac deformation due to its high ***,the gelatin characteristics of the biodegradable GCF enable the sensor to monitor and support tissue *** GCF metamaterial design offers a unique idea for bioelectronics to develop implantable sensors that integrate monitoring and tissue repair and a customized method for endowing implanted sensors to be highly conformal with soft tissues.

关键词： Implantable hydrogel-based bioelectronics Conformality 3D printing Metamaterial design

Physics-Informed Neural Networks with Two Weighted Loss Function Methods for Interactions of Two-Dimensional Oceanic Internal Solitary Waves

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Journal of Systems Science & Complexity 2024年第2期37卷 545-566页

作者： SUN Junchao chen yong TANG Xiaoyan School of Mathematical Sciences Key Laboratory of Mathematics and Engineering Applications(Ministry of Education)&Shanghai Key Laboratory of PMMPEast China Normal UniversityShanghai 200241China College of Mathematics and Systems Science Shandong University of Science and TechnologyQingdao 266590China

The multiple patterns of internal solitary wave interactions(ISWI)are a complex oceanic *** remote sensing techniques indirectly detect these ISWI,but do not provide information on their detailed structure and ***,the authors considered a three-layer fluid with shear flow and developed a(2+1)Kadomtsev-Petviashvili(KP)model that is capable of describing five types of oceanic ISWI,including O-type,P-type,TO-type,TP-type,and *** learning models,particularly physics-informed neural networks(PINN),are widely used in the field of fluids and internal solitary ***,the authors find that the amplitude of internal solitary waves is much smaller than the wavelength and the ISWI occur at relatively large spatial scales,and these characteristics lead to an imbalance in the loss function of the PINN *** solve this problem,the authors introduce two weighted loss function methods,the fixed weighing and the adaptive weighting methods,to improve the PINN *** successfully simulated the detailed structure and dynamics of ISWI,with simulation results corresponding to the satellite *** particular,the adaptive weighting method can automatically update the weights of different terms in the loss function and outperforms the fixed weighting method in terms of generalization ability.

关键词： Internal solitary wave interactions KP equation PINN method weighted loss function method

High-order Soliton Matrix for the Third-order Flow Equation of the Gerdjikov-Ivanov Hierarchy Through the Riemann-Hilbert Method

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Acta Mathematicae Applicatae Sinica 2024年第2期40卷 358-378页

作者： Jin-yan ZHU yong chen School of Mathematical Sciences Shanghai Key Laboratory of Pure Mathematics and Mathematical PracticeEast China Normal UniversityShanghai 200062China College of Mathematics and Systems Science Shandong University of Science and TechnologyQingdao 266590China

The Gerdjikov-Ivanov(GI)hierarchy is derived via recursion operator,in this article,we mainly investigate the third-order flow GI *** the framework of the Riemann-Hilbert method,the soliton matrices of the third-order flow GI equation with simple zeros and elementary high-order zeros of Riemann-Hilbert problem are constructed through the standard dressing *** advantage of this result,some properties and asymptotic analysis of single soliton solution and two soliton solution are discussed,and the simple elastic interaction of two soliton are *** with soliton solution of the classical second-order flow,we find that the higher-order dispersion term affects the propagation velocity,propagation direction and amplitude of the ***,by means of a certain limit technique,the high-order soliton solution matrix for the third-order flow GI equation is derived.

关键词： Gerdjikov-Ivanov hierarchy third-order flow GI equation Riemann-Hilbert method high-order soliton

Long-time Asymptotics for the Reverse Space-time Nonlocal Hirota Equation with Decaying Initial Value Problem:without Solitons

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Acta Mathematicae Applicatae Sinica 2024年第3期40卷 708-727页

作者： Wei-qi PENG yong chen School of Mathematical Sciences East China Normal UniversityShanghai 200241China College of Mathematics and Systems Science Shandong University of Science and TechnologyQingdao 266590China

In this work,we mainly consider the Cauchy problem for the reverse space-time nonlocal Hirota equation with the initial data rapidly decaying in the solitonless *** from the Lax pair,we first construct the basis Riemann-Hilbert problem for the reverse space-time nonlocal Hirota ***,using the approach of Deift-Zhou nonlinear steepest descent,the explicit long-time asymptotics for the reverse space-time nonlocal Hirota is *** the reverse space-time nonlocal Hirota equation,since the symmetries of its scattering matrix are different with the local Hirota equation,the v(λ_(i))(i=0,1)would like to be imaginary,which results in theδ_(λi)^(0)contains an increasing t(±Imv(λ_(i)))/2,and then the asymptotic behavior for nonlocal Hirota equation becomes differently.

关键词： Riemann-Hilbert problem reverse space-time nonlocal Hirota equation long-time asymptotics nonlinear steepest descent method