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Ileal pouch surgery for ulcerative colitis

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World Journal of gastroenterology 2007年第24期13卷 3288-3300页

作者： simon P Bach neil J Mortensen Department of Colorectal Surgery John Radcliffe Hospital Oxford OX3 9DU United Kingdom

Ulcerative colitis (UC) is a relapsing and remitting disease characterised by chronic mucosal and submucosal inflammation of the colon and rectum. Treatment may vary depending upon the extent and severity of inflammation. Broadly speaking medical treatments aim to induce and then maintain remission. Surgery is indicated for inflammatory disease that is refractory to medical treatment or in cases of neoplastic transformation. Approximately 25% of patients with UC ultimately require colectomy. Ileal pouch-anal anastomosis (IPAA) has become the standard of care for patients with ulcerative colitis who ultimately require colectomy. This review will examine indications for IPAA, patient selection, technical aspects of surgery, management of complications and long term outcome following this procedure.

关键词： Ulcerative colitis Ileal Pouch Ileal pouch anal anastomosis

Current and future applications of ultrasound imaging in peripheral nerve disorders

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World Journal of Radiology 2020年第6期12卷 101-129页

作者： Antonia S Carroll neil g.simon Brain and Mind Research Centre University of SydneyCamperdown 2050NSWAustralia Department of Neurology Westmead HospitalUniversity of SydneyWestmead 2145NSWAustralia Department of Neurology St Vincent’s HospitalSydneyDarlinghurst 2010NSWAustralia Northern Clinical School University of SydneyFrenchs Forest 2086NSWAustralia

Neuromuscular ultrasound(NMUS) is a rapidly evolving technique used in neuromuscular medicine to provide complimentary information to standard electrodiagnostic studies. NMUS provides a dynamic, real time assessment of anatomy which can alter both diagnostic and management pathways in peripheral nerve disorders. This review describes the current and future techniques used in NMUS and details the applications and developments in the diagnosis and monitoring of compressive, hereditary, immune-mediated and axonal peripheral nerve disorders, and motor neuron diseases. Technological advances have allowed the increased utilisation of ultrasound for management of peripheral nerve disorders;however, several practical considerations need to be taken into account to facilitate the widespread uptake of this technique.

关键词： Neuromuscular ultrasound Peripheral neuropathy Polyneuropathy Entrapment neuropathy Immune-mediated neuropathy Hereditary neuropathy

Essential biology neil A. Campbell, Jane B. Reece, Eric J. simon. 2nd ed.

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Essential biology Neil A. Campbell, Jane B. Reece, Eric J. S...

Conservation needs of amphibians in China: A review

2004年

作者： neil A. Campbell Jane B. Reece Eric J. simon.

Student CD-ROM includes: Activities, process of sciences, quizzes, flashcards, glossary.

ISBN: (纸本)0805374957

Student CD-ROM includes: Activities, process of sciences, quizzes, flashcards, glossary.

关键词： Biology.

来源：畅想之星图书光盘版（南... 评论

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Science China(Life Sciences) 2007年第2期50卷 265-276页

作者： Michael Wai Neng LAU simon N STUART Janice S CHANSON neil A COX Debra L FISCHMAN Kadoorie Farm and Botanic garden Hong Kong China IUCN-SSC/CI-CABS Biodiversity Assessment Unit Center for Applied Biodiversity Science Conservation International Washing-ton DC 20036 USA gIS Laboratory Center for Applied Biodiversity Science Conservation International Washington DC 20036 USA

The conservation status of all the amphibians in China is analyzed,and the country is shown to be a global priority for conservation in comparison to many other countries of the *** Chinese regions are particularly rich in amphibian diversity:Hengduan,Nanling,and Wuyi ***-manders are more threatened than frogs and *** smaller families show a high propensity to become seriously threatened:Bombinatoridae,Cryptobranchidae,Hynobiidae and *** other parts of the world,stream-breeding,high-elevation forest amphibians have a much higher likeli-hood of being seriously *** loss,pollution,and over-harvesting are the most serious threats to Chinese ***-harvesting is a less pervasive threat than habitat loss,but it is more likely to drive a species into rapid *** conservation challenges are mentioned with recommendations for the highest priority research and conservation actions.

关键词： amphibians conservation status priority of the regions and animal group habitat preferences conservation challenge conservation recom-mendation

Targeted therapy for advanced gastric cancer: A review of current status and future prospects

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World Journal of gastrointestinal Oncology 2015年第12期7卷 401-410页

作者： Ozkan Kanat Bert O'neil Safi Shahda Department of Medical Oncology Uludag University faculty of Medicine simon Cancer Center Indiana University School of Medicine

In the West in particular, the vast majority of gastric cancer(gC) patients present with advanced-stage disease. Although combination chemotherapy is stillthe most important component of treatment for these patients, it confers a modest survival advantage. Recently, increased knowledge of the key molecular signaling pathways involved in gastric carcinogenesis has led to the discovery of specific molecular-targeted therapeutic agents. Some of these agents such as trastuzumab and ramucirumab have changed the treatment paradigm for this disease. In this paper, we will summarize the current clinical status of targeted drug therapy in the management of gC.

关键词： gastric cancer Targeted therapy Angiogenesis Epide

Colorectal cancer risk following appendectomy:a pooled analysis of three large prospective cohort studies

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Cancer Communications 2022年第5期42卷 486-489页

作者： Joseph A.Rothwell Nagisa Mori Fanny Artaud Agnès Fournier Marco Conte Marie-Christine Boutron-Ruault simon S.M.Chan Marc J.gunter neil Murphy gianluca Severi UniversitéParis-Saclay UVSQInsermGustave RoussyExposome and Heredity teamCentre for Epidemiology and Population Health(CESP U1018)Villejuif 94800France Nutrition and Metabolism Branch International Agency for Research on Cancer(IARC)150 Cours Albert ThomasLyon 69008France Department of gastroenterology Norfolk and Norwich University Hospital NHS TrustNorwich NR47UYUnited Kingdom Department of Medicine Bob Champion Research and Education BuildingNorwich Medical SchoolUniversity of East AngliaNorwich NR47UQUnited Kingdom Department of Statistics Computer ScienceApplications“G.Parenti”University of FlorenceFlorence 50134Italy

Dear Editor,Appendectomy is usually performed to treat acute appendicitis although it may also be conducted in the absence of appendicitis when patients suffer from chronic abdominal *** is also known to mitigate the risk of ulcerative colitis[1],a risk factor for colorectal *** impact of appendectomy on colorectal cancer risk,particularly in the long term,is *** procedurewas initially hypothesized to increase colorectal cancer risk due to decreased immunocompetency.

关键词： cancer colorectal acute

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中国两栖动物保护需求总述

中国科学（C辑） 2006年第6期36卷 570-580,581页

作者：谢锋刘惠宁 simon N Stuart Janice S Chanson neil A Cox Debra L Fischman 中国科学院成都生物研究所嘉道理农场和植物园 IUCN-SSC/CI-CABS Biodiversity Assessment Unit Center for Applied Biodiversity Science Conservation International Washington DC 20036 USA gIS Laboratory Center for Applied Biodiversity Science Conservation International Washington DC 20036 USA

通过对中国两栖动物物种生物多样性现状的全面分析,与世界许多国家相比,中国是一个重要的全球优先保护地区.横断山区、南岭山区和武夷山区3个区域的两栖动物物种多样性特别丰富.有尾两栖类物种较无尾类受胁程度更高.几个物种数相对较少... 详细信息

通过对中国两栖动物物种生物多样性现状的全面分析,与世界许多国家相比,中国是一个重要的全球优先保护地区.横断山区、南岭山区和武夷山区3个区域的两栖动物物种多样性特别丰富.有尾两栖类物种较无尾类受胁程度更高.几个物种数相对较少的铃蟾科、隐腮鲵科、小鲵科和蝾螈科显示出了高的受胁倾向.像世界其它地方一样,高海拔地区溪流繁殖的森林物种受胁程度更高.对中国两栖动物而言,生境丧失、污染和过度捕捉是最主要的致危因素.过度捕捉虽然影响不如生境丧失深远,但它更可能导致一个物种种群的快速衰落.针对5个方面的保护挑战,提出了优先研究领域和保护行动方面的建议.

关键词：两栖动物保护现状优先区域和类群适合生境保护挑战保护建议

Effect of 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide and N-hydroxysuccinimide concentrations on the mechanical and biological characteristics of cross-linked collagen fibres for tendon repair

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Regenerative Biomaterials 2015年第2期2卷 77-85页

作者： Zafar Ahmad Jennifer H.Shepherd David V.Shepherd Siddhartha ghose simon J.Kew Ruth E.Cameron Serena M.Best Roger A.Brooks John Wardale neil Rushton Orthopaedic Research Unit Department of Surgery University of CambridgeAddenbrooke’s HospitalCambridgeCB20QQUK Department of Materials Science and Metallurgy University of CambridgeCambridgeCB30FSUK Tigenix Ltd CambridgeCB40FYUK

Reconstituted type I collagen fibres have received considerable interest as tendon implant materials due to their chemical and structural similarity to the native *** produced through a semi-continuous extrusion process were cross-linked with different concentrations of the zerolength cross-linker 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide(EDC)in combination with N-hydroxysuccinimide(NHS).Tensile properties of the fibres were considered,along with imaging of both surface structure and fibrillar *** of the fibres to bacterial collagenase was investigated and fibre sections seeded with human tendon cells for biological characterization,including cell adhesion and *** work clearly demonstrated that whilst the concentration of EDC and NHS had no significant effect on the mechanics,a higher concentration was associated with higher collagenase resistance,but also provided a less attractive surface for cell adhesion and proliferation.A lower cross-linking concentration offered a more biocompatible material without reduction in mechanics and with a potentially more optimal degradability.

关键词： biopolymer scaffolds soft tissue

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考试与评价（英语高一专刊） 2016年第4期 1-1页

作者： neil simon