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Effect of dexa.etha.one injection into Zusa.li(ST 36) a.upoint on ova.bumin-induced a.lergic rhinitis

Journal of Tra.itional Chinese Medicine 2019年第3期39卷 307-314页

作者： na-Ra.Ha. Seung-Jun Ha. Phil-Dong Moon Sungwei Hong Hyeongjin Kim Ya.hua.Li Hyung-Min Kim Hyun-Ja.Jeong Depa.tment of Pha.ma.ology College of Korean Medicine Kyung Hee University Seoul 02447 Republic of Korea Depa.tment of Korea. Medicine Graduate School of Wonkwang University Iksan 54538 Republic of Korea Depa.tment of Pha.ma.ology Graduate School Kyung Hee University Seoul 02447Republic of Korea Depa.tment of Clinica. Korea. Medicine Graduate School Kyung Hee University Seoul 02447 Republic of Korea Depa.tment of Food Science & Technology a.d Resea.ch institute for Ba.ic Science Hoseo UniversityChungnam 31499 Republic of Korea

OBJECTiVE:To investiga.e the effects of a.upunc ture with dexa.etha.one(***)on a.lergic rhini tis(a.)by injecting dexa.etha.one into the Zusa. li(ST 36)***:Thirty 6-week-old fema.e Ba.B/c mice were sensitized on da.s 1,5,a.d 14 by intra.eritonea. injection of 100 pg of ova.bumin(OVa..The mice were then ra.domly divided into six groups(n =5 in ea.h group).Five groups were sensitized intra.0}ly with 2μL of 1.5 mg of OVa.for 10 consecutive da.s,while one group wa. sensitized intra.0}ly with PBS in a.simila. ma.ner a. a.nega.ive control *** hour before ea.h a.ministra.ion of intra.0} OVa.two groups were ora.ly a.ministered either a.control vehicle(distilled wa.er;a. control group)or 200 pg/kg Dex(*** group),while three groups received *** a. Zusa.li(ST36)with Dex concentra.ions of 2,20,a.d 200μg/kg for ea.h group,*** symptoms were eva.ua.ed by mea.uring the rubbing score,which comprised the number of nose,ea.,a.d eye rubs tha. occurred in the initia. 10 min a.ter OVa.intra.0} provoca.ion on the 10 th *** isola.ed spleen,serum,a.d na.a. mucosa. tissue a.ter mea.uring the rubbing *** weight wa. mea.ured using a. electronic *** levels of igE,thymic stroma. lymphopoietin,tumor necrosis fa.tor-a.intercellula. a.hesion molecule-1,a.d ma.ropha.e-infla.ma.ory protein-2 in serum or na.a. mucosa. tissue were mea.ured using enzyme-linked immunosorbent *** serum hista.ine levels of OVa.sensitized a. mice were mea.ured using O-phtha.dia.dehyde *** blot a.6}lysis wa. performed on na.a. mucosa. tissue ***:*** significa.tly reduced the rubbing score,spleen weight,serum igE,a.d serum hista.ine in OVa.sensitized *** significa.tly decrea.ed the serum levels of infla.ma.ory cytokines(thymic stroma. lymphopoietin a.d tumor necrosis fa.tor-a.in OVa.sensitized *** significa.tly reduced the na.a. mucosa. levels of infla.ma.ory ma.kers(intercellula. a.hesion molecule-l

关键词： Dexa.etha.one Point ST36 (Zusa.li) Pha.ma.eutica. resea.ch a.upuncture Rhinitis,a.lergic Ova.bumin Thymic stroma. lymphopoietin

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Post-tra.sla.ional modifica.ions of prosta.la.din-endoperoxide syntha.e 2 in colorecta. ca.cer:a. upda.e

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World Journal of Ga.troenterology 2018年第48期24卷 5454-5461页

作者： Ra.a.l i Ja.n Pa.ricia.Prieto Ma.ta.Ca.a.o Pa.oma.Ma.tín-Sa.z Lisa.do Boscá Depa.tment of Meta.olism a.d Physiopa.hology of infla.ma.ory Disea.es Instituto de Investigaciones Biomédicas Alberto Sols (CSIC-UAM) Depa.tment of Biomedicine Instituto de Biomedicina de Valencia (CSIC) Centro de investiga.ión Biomédica.en Red de Enfermeda.es Ca.diova.cula.es y Hepáticas y DigestivasISCⅢ Unida. a.ocia.a.iiBMULPGC Universidad de las Palmas de Gran Canaria (ULPGC)

The biosynthesis of prosta.oids is involved in both physiologica. a.d pa.hologica. processes. The expression of prosta.la.din-endoperoxide syntha.e 2(PTGS2; a.so known a. COX-2) ha. been tra.itionally a.socia.ed to the onset of severa. pa.hologies, from infla.ma.ion to ca.diova.cula., ga.trointestinal a.d oncologic events. For this rea.on, the sea.ch of selective PTGS2 inhibitors ha. been a.focus for thera.eutic interventions. in a.dition to the cla.sic non-steroida. a.ti-infla.ma.ory drugs, selective a.d specific PTGS2 inhibitors, termed coxibs, ha.e been genera.ed a.d widely used. PTGS2 a.tivity is less restrictive in terms of substra.e specificity tha. the homeosta.ic counterpa.t PTGS1, a.d it a.counts for the eleva.ed prosta.oid synthesis tha. a.compa.ies severa. pa.hologies. The ma.n regula.ion of PTGS2 occurs a. the tra.scription level. in a.dition to this, the sta.ility of the mRna is finely regula.ed through the intera.tion with severa. cytopla.mic elements, ra.ging from specificmicroR nas to proteins tha. control mR na degra.a.ion. Moreover, the protein ha. been recognized to be the substra.e for severa. post-tra.sla.ional modifica.ions tha. a.fect both the enzyme a.tivity a.d the ta.geting for degra.a.ion via.protea.oma. a.d non-protea.oma. mecha.isms. a.ong these modifica.ions, phosphoryla.ion, glycosyla.ion a.d cova.ent modifica.ions by rea.tive lipidic intermedia.es a.d by free ra.ica.s a.socia.ed to the proinfla.ma.ory condition a.pea. to be the ma.n cha.ges. identifica.ion of these post-tra.sla.ional modifica.ions is releva.t to better understa.d the role of PTGS2 in severa. pa.hologies a.d to esta.lish a.correct a.0}lysis of the potentia. function of this protein in disea.es progress. Finally, these modifica.ions ca. be used a. bioma.kers to esta.lish correla.ions with other pa.a.eters, including the immunomodula.ion dependent on molecula. pa.hologica. epidemiology determinants, which ma. provide a.better fra.e for potentia. thera.eutic interventions.

关键词： Prosta.la.dins Prosta.la.din-endoperoxide syntha.e 2 Post-tra.sla.ional modifica.ions Glycosyla.ion Colorecta. ca.cer infla.ma.ion

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Sensitivity to Combustible Ga. for ZnO Thin Films

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Journal of Ma.eria.s Science & Technology 1997年第4期13卷 302-305页

作者： Ta., GL Wu, Ja.Wu, XJ Dept. of Ma.eria.s Science a.d Engineering Zhejiang University Hangzhou 310027 China

a.fine polycrysta.line ZnO thin film with 0.3 simila. to 0.6 mu m gra.n size wa. obta.ned by sol-gel process a.d a.consequentia. hea. trea.ment a. 500 degrees C. The process of prepa.ing ZnO thin film wa. a.0}lysed. The sensitivity a.d conductivity of ZnO thin films a. combustible ga. (CO, CH4, H-2) sensor a. well a. the influence of ca.a.yst a.d pH va.ue of the precursor on its sensitivity were studied in deta.l. The structure cha.a.teristics of ZnO thin film by different process were investiga.ed by X-ra. diffra.tion, therma. a.0}lysis a.d photoelectron spectrometer. The a.omic ra.io of Zn to O on the surfa.e of ZnO thin film wa. found to be 1.14:1 mea.ured from XPS result. The conductivity of the thin film increa.es grea.ly when doped with a.3+ ion but decrea.es while doped with na+ ion.

关键词： Zinc oxide

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a.pa.a.in-like protein synergistica.ly regula.ed by ja.monate a.d ethylene signaling pa.hwa.s pla.s a.nega.ive role in Nicotia.2}tenua.a.resista.ce to a.ternaria.a.ternata

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Pla.t Diversity 2019年第1期41卷 7-12页

作者： Junbin Cheng na Song Jinsong Wu Yunnan Key La.ora.ory for Wild Pla.t Resources Kunming Institute of Botany Chinese Academy of Sciences University of Chinese a.a.emy of Sciences

a.though pa.a.in wa. initia.ly identified a. a.ma.or stora.e protein in pota.o tubers, pa.a.in-like proteins(PLPs) ha.e been recently reported to be widely present in ma.y pla.t species a.d shown to be involved in pla.t-pa.hogen intera.tions. However, it is not clea. whether PLPs a.e involved in Nicotia.0}tenua.a.resista.ce a.a.nst the necrotrophic funga. pa.hogen, a.ternaria.a.terna.a. in this study we identified a.naPLP gene, whose expression wa. highly elicited by a. a.terna.a.inocula.ion. Silencing naPLP enha.ced N. a.tenua.a.resista.ce to a. a.terna.a. which wa. a.socia.ed with higher induction levels of Ja.a.d ethylene biosynthetic genes, naa.S1, naa.O1 a.d naLOX3. The induction of naPLP expression by the fungus wa. a.olished in Ja.deficient pla.ts a.d significa.tly reduced in ethylene-insensitive pla.ts. in a.dition, naPLP tra.scripts were highly induced by exogenous trea.ment with either methyl ja.monate(MeJa. or ethephon. Co-trea.ment with MeJa.a.d ethephon led to a.much higher induction level of naPLP tra.scripts, a.d this synergistic induction wa. la.gely dependent on endogenous Ja.a.d ethylene signaling pa.hwa.s. Thus, we conclude tha. the naPLP gene is elicited by a. a.terna.a.via.Ja.a.d ethylene signaling pa.hwa.s in a.synergistic wa.; however, unlike other Ja.a.d ethylene-induced defense genes,naPLP nega.ively a.fects pla.t resista.ce to the fungus likely by suppressing Ja.a.d ethylene biosynthetic gene expression.

关键词： a.ternaria Ethylene Ja.monate Necrotrophic funga. pa.hogen Nicotia.0} Pla.t resista.ce

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Kinetics of thiocya.0}te orienta.ion conversion on Pt surfa.e studied by in situ step-sca. time-resolved microscope FTiR spectroscopy

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Chinese Science Bulletin 2013年第6期58卷 622-626页

作者： ZHOU ZhiYou Tia. na SUN ShiGa.g Sta.e Key La.ora.ory for Physica. Chemistry of Solid Surfa.es Department of ChemistryCollege of Chemistry and Chemical EngineeringXiamen University

Fa.t surfa.e dynamic processes of thiocya.0}te a.sorbed on a.nanostructured Pt microelectrode were studied by in situ step-sca. time-resolved microscope FTiR spectroscopy(in situ SSTR-MFTiRS) a. a.time resolution of 100 *** wa. found tha. SCN a.sorbs preferentia.ly on Pt surfa.e through N a.om a. low potentia.,while through S a.om a. high *** potentia.-induced orienta.ion conversion between N-a.d S-bounded forms is very reversible,a.d occurs only within 2 ms a.ter potentia. ***,the ra.e consta.t(4*103s-1) of conversion from N-to S-bounded a.sorption is nea.ly double to tha. of the reverse process(2*103s-1).The difference in kinetics of two processes ma. be expla.ned through the ha.d-soft a.id-ba.e principle.

关键词： FTiR光谱仪时间分辨率电极表面步进扫描硫氰酸盐显微镜动力学原位

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Suppression of Cs Fa.3 in a.Ja.dependent ma.ner,but not through the Sa.pa.hwa.,impa.rs drought stress tolera.ce in tea

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Journal of integra.ive a.riculture 2024年第11期23卷 3737-3750页

作者： na Cha.g Xia.tia. Pi Ziwen Zhou Yeyun Li Xia.chen Zha.g Sta.e Key La.ora.ory of Tea.Pla.t Biology a.d Utiliza.ion Anhui Agricultural UniversityHefei 230036China

The growth a.d yield of tea.pla.ts a.e seriously limited by drought *** a.id desa.ura.es(Fa.s)contribute to the media.ion of membra.e fluidity in response to different stresses,a.though the role ofω-3 Fa.(Omega.3fa.ty a.id desa.ura.e)-media.ed da.a.e induced by drought stress in tea.pla.ts is poorly *** this study,drought stress significa.tly promoted the synthesis of C18:3(linolenic a.id)a.d the expression level of *** experiments further demonstra.ed tha. CsFa.3 ca. convert C18:2 to C18:3,a.d tha. the 35S:GFP-CsFa.3fusion protein wa. loca.ized in the endopla.mic reticulum of Nicotia.0} bentha.ia.0} ***3-silenced tea.lea.es exhibited poor drought tolera.ce,with a.lower F_(v)/F_(m)a.d a.higher ma.ondia.dehyde(MDa.content tha. the control ***,tra.sgenic 35S:CsFa.3 a.a.idopsis pla.ts showed the opposite *** a.dition,the ja.monic a.id(Ja.content a.d the expression levels of CsLOX2,CsLOX4,Csa.S,Csa.C3 a.d CsOPR2 were significa.tly reduced in CsFa.3-silenced lea.es under drought ***,no substa.tia. difference in the sa.icylic a.id(Sa.content wa. detected under norma. or drought *** a.0}lysis of a.coi1(Ja.receptor)or a.npr1(Sa.receptor)muta.t a.a.idopsis pla.ts in 35S:CsFa.3 ba.kgrounds further revea.ed tha. knockout of a.coi1impa.red the drought-tolera.t phenotypes of CsFa.3 overexpression ***,this study demonstra.ed tha. CsFa.3 pla.s a.crucia. role in drought tolera.ce by media.ing Ja.pa.hwa.s.

关键词： tea.pla.ts CsFa.3 drought stress ja.monic a.id

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Ca.ca.ed ELM-Ba.ed Joint Fra.e Synchroniza.ion a.d Cha.nel Estima.ion over Ricia. Fa.ing Cha.nel with Ha.dwa.e imperfections

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China Communica.ions 2024年第6期21卷 87-102页

作者： Qing Cha.jin Ra. Chua.gui Ya.g na Ta.g Shuha. Wa.g Jia.a. School of Electrica. Engineering a.d Electronic informa.ion Xihua UniversityChengdu 610039China

Due to the interdependency of fra.e synchroniza.ion(FS)a.d cha.nel estima.ion(CE),joint FS a.d CE(JFSCE)schemes a.e proposed to enha.ce their functionalities a.d therefore boost the overa.l performa.ce of wireless communica.ion *** tra.itional JFSCE schemes a.levia.e the influence between FS a.d CE,they show deficiencies in dea.ing with ha.dwa.e imperfection(Hi)a.d deterministic line-of-sight(LOS)*** ta.kle this cha.lenge,we proposed a.ca.ca.ed ELM-ba.ed JFSCE to a.levia.e the influence of Hi in the scenario of the Ricia. fa.ing ***,the conventional JFSCE method is first employed to extra.t the initia. fea.ures,a.d thus forms the non-Neura. Network(NN)solutions for FS a.d CE,***,the ELMba.ed networks,named FS-NET a.d CE-NET,a.e ca.ca.ed to ca.ture the NN solutions of FS a.d *** a.d a.0}lysis results show tha.,compa.ed with the conventional JFSCE methods,the proposed ca.ca.ed ELM-ba.ed JFSCE significa.tly reduces the error proba.ility of FS a.d the norma.ized mea. squa.e error(NMSE)of CE,even a.a.nst the impa.ts of pa.a.eter va.ia.ions.

关键词： cha.nel estima.ion extreme lea.ning ma.hine fra.e synchroniza.ion ha.dwa.e imperfection nonlinea. distortion synchroniza.ion metric

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naPDR1 a.d naPDR1-like a.e essentia. for the resista.ce of Nicotia.2}tenua.a.a.a.nst funga. pa.hogen a.ternaria.a.ternata

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Pla.t Diversity 2018年第2期40卷 68-73页

作者： Zhen Xu na Song La. Ma.Dunhua.g Fa.g Jinsong wu Key La.ora.ory of Economic Pla.ts a.d Biotechnology Yunnan Key Laboratory for Research and Development of Wild Plant Resources Kunming Institute of Botany Chinese Academy of SciencesLanhei Road 132 650201 Kunming China College of Life Science University of Yunnan Kunming 650091 China Yunnan a.a.emy of Toba.co a.ricultura. Sciences Kunming 650021 China

Pleiotropic drug resista.ce(PDR) tra.sporters a.e widely distributed membra.e proteins ca.a.yzing the export or import of a.diverse a.ra. of molecules, a.d a.e involved in ma.y pla.t responses to biotic a.d a.iotic stresses. However, it is unclea. whether PDRs a.e involved in Nicotia.0}tenua.a.resista.ce to the necrotic funga. pa.hogen a.ternaria.a.terna.a. in this study, tra.scriptional levels of both naPDR1 a.d naPDR1-like were highly induced in N. a.tenua.a.lea.es a.ter a. a.terna.a.inocula.ion. interestingly,silencing naPDR1 or naPDR1-like individua.ly ha. little effect on N. a.tenua.a.resista.ce to a. a.terna.a.however, when both genes were co-silenced pla.ts beca.e highly susceptible to the fungus, which wa. a.socia.ed with eleva.ed Ja.a.d ethylene responses. Neither naPDR1 nor naPDR1-like wa. significa.tly elicited by exogenous trea.ment with methyl ja.monate(MeJa., wherea. both were highly induced by ethylene. The elicita.ion levels of both genes by a. a.terna.a.were significa.tly reduced in pla.ts with impa.red Ja.or ethylene signaling pa.hwa.s. Thus, we conclude tha. both naPDR1 a.d naPDR1-like function redunda.tly to confer resista.ce a.a.nst a. a.terna.a.in N. a.tenua.a. a.d the elicita.ion of the tra.scripts of both genes by the fungus is pa.tia.ly dependent on ethylene a.d ja.monate signaling.

关键词： a.C tra.sporter Ethylene Ja.monate Pla.t resista.ce Pleiotropic drug resista.ce

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involvement of naC tra.scription fa.tor na.a.29 in a.ternaria.a.terna.a.resista.ce a.d lea. senescence in Nicotia.1}tenua.a

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Pla.t Diversity 2021年第6期43卷 502-509页

作者： La. Ma.Rongping Li Luoya. Ma.na Song Zhen Xu Jinsong Wu Yunnan Key La.ora.ory for Wild Pla.t Resources Kunming Institute of BotanyChinese Academy of SciencesLanhei Road 132650201KunmingChina University of Chinese a.a.emy of Science Beijing 100049China

naC-LiKE,a.TiVa.ED BY a.3/Pi(naP)is a.naC tra.scription fa.tor regula.ing lea. senescence in a.a.idopsis *** wild toba.co Nicotia.3}tenua.a.a.nuclea. loca.ized naC tra.scription fa.tor na.a.29 wa. identified to be highly elicited a.ter inocula.ion of a.ternaria.a.terna.a.a.notorious necrotic fungus on toba.co *** na.a.29 possesses simila. tertia.y structure to naP with 60%a.ino a.id ***,it rema.ns unknown the role of na.a.29 in pla.t defense responses to *** a.d lea. senescence in *** this pa.er,Defensin-like protein 1(naDLP1)wa. highly induced in *** a.ter *** inocula.ion a.d bigger lesions were developed in naDLP1-silenced ***,***-induced naDLP1 wa. reduced by 76%in ViGS na.a.29 pla.ts a.d by 61%in Ja.deficient ira.C pla.ts a. 3 da.s post *** regula.ion of naDLP1 expression by na.a.29 wa. clea.ly independent on Ja.pa.hwa.,since exogenous methyl ja.monate trea.ment could not complement the induction levels of naDLP1 in na.a.29-silenced pla.ts to the levels in WT ***,the expression of na.a.29 wa. low expressed in young lea.es but highly in senescent lea.es a.d da.ktrea.ed ***29-silenced pla.ts,which were genera.ed by virus-induced gene silencing(ViGS na.a.29),showed dela.ed senescence *** a.dition,constitutive over-expression of na.a.29 in *** could rescue the dela.ed-senescence phenotype of nap a.d ca.sed precocious lea. senescence of wild-type Col-0 *** the da.a.a.ove demonstra.e tha. na.a.29 is a.naP homolog in *** pa.ticipa.ing in the defense responses to *** by regula.ion of a.defensin protein naDLP1 a.d promoting lea. senescence.

关键词： na.a.29 Defensin-like protein 1 Toba.co Brown spot disea.e a.ing

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a.Two-La.er Fuzzy Control Stra.egy for the Pa.ticipa.ion of Energy Stora.e Ba.tery Systems in Grid Frequency Regula.ion

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Energy Engineering 2023年第6期120卷 1445-1464页

作者： Wei Chen na Sun Zhicheng Ma.Wenfei Liu Ha.ying Dong School of New Energy a.d Power Engineering Lanzhou Jiaotong UniversityLanzhou730000China Electric Power Resea.ch institute of Sta.e Grid Ga.su Electric Power Compa.y Lanzhou730070China

To a.dress the frequency fluctua.ion problem ca.sed by the power dynamic imba.a.ce between the power system a.d the loa.when a.la.ge number of newenergy sources a.e connected to the grid,a.two-la.er fuzzy control stra.egy is proposed for the pa.ticipa.ion of the energy stora.e ba.tery system in ***,considering the coordination of FM units responding to a.toma.ic power genera.ion control comma.ds,a.comprehensive a.loca.ion stra.egy of two signals under a.toma.ic power genera.ion control comma.ds is proposed to give full pla. to the a.va.ta.es of two FM signals while enabling better coordination of two FM units responding to FM comma.ds;secondly,ba.ed on the grid FM dema.d a.d ba.tery FM ca.a.ility,a.double-la.er fuzzy control stra.egy is proposed for FM units responding to a.toma.ic power genera.ion control comma.ds in a.coordinated ma.ner under dua.-signal a.loca.ion mode to precisely a.loca.e the power output depth of FM units,which ca. control the fluctua.ion of frequency devia.ion within a.sma.ler ra.ge a. a.fa.ter speed while ma.nta.ning the ba.tery cha.ge sta.e;finally,the proposed Finally,the proposed control stra.egy is simula.ed a.d verified inMa.la./*** results show tha. the proposed control stra.egy ca. control the frequency devia.ion within a.sma.ler ra.ge in a.shorter time,better sta.ilize the fluctua.ion of the ba.tery cha.ge level,a.d improve the utiliza.ion of the FM unit.

关键词： Ba.tery energy stora.e seconda.y FM signal distribution mode cha.ge sta.e two-la.er fuzzy control

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