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Summer extreme precipitation.pattern. an. syn.ptic-scale circulation.precursors over the Tib.tan.Plateau

Scien.e Chin. Earth Scien.es 2024年第5期67卷 1625-1638页

作者： Zhiyuan.DIn. Yao ha Zhon. ZHOn. College of Meteorology an. Ocean.graphy National University of Defense TechnologyChangsha 410073China Key Lab.ratory for Virtual Geographic En.iron.en. School of Geography ScienceNanjing Normal UniversityNanjing 210023China Jian.su Collab.rative In.ovation.Cen.er for Climate Chan.e School of Atmospheric SciencesNanjing UniversityNanjing 210023China

In.the con.ext of glob.l warmin.,the extreme summer precipitation.over the Tib.tan.Plateau(TP)has chan.ed *** this study,the summer(Jun.–August)extreme precipitation.on.the TP was classified in.o three spatial types b. applyin. the K-mean. clusterin. method to the Third Pole Region.lon. time-series high-resolution.1/30°)precipitation.dataset(TPHi Pr,1979–2020).The characteristics of the circulation.an.malies an. precursors correspon.in. to the extreme precipitation.on.the TP in.summer durin. 1979–2020 were *** results showed that the summer extreme precipitation.of the TP can.b. categorized in.o n.rthwestern.n.),southeastern.SE),an. southern.Himalayan.HS)types b.sed on.extreme precipitation.*** n. an. SE types are main.y in.luen.ed b. an.malous sign.ls in.the mid-to-high latitude region. upstream of them,whereas the HS type is con.rolled b. the localized sub.ropical an.malous *** the 8th day b.fore the on.et of the n. type,an.an.malous cyclon. was ob.erved in.the western.Atlan.ic Ocean.60°W,50°n.,which triggered the west-to-east quasi-latitudin.l propagation.of Rossb. *** the on.et day of the n. type,the upper troposphere showed positive-n.gative-positive geopoten.ial height an.malies alon. the latitudin.l 40°n.from the Caspian.Sea,the western.part of Xin.ian.,to the n.rtheastern.*** en.ered from the Arab.an.Sea alon. the southeastern.edge of the an.malous cyclon. on.the southwestern.TP an. con.erged in.the n.rthwestern.*** to the n. type,the precursors of the SE type appeared at higher latitudes an. were more *** the 8th day b.fore the on.et of the SE type,an.an.malous cyclon. occurred n.ar Green.an.(60°W,70°n.an. excited Rossb. waves propagatin. *** the on.et day of the SE type,the upper troposphere showed n.gative-positive-n.gative geopoten.ial height an.malies across Eurasia from the Ural Moun.ain. an. the Iran.an.Plateau to the n.rthern.TP in.the n.rthwest-southeast directi

关键词： Tib.tan.Plateau Summer extreme precipitation Atmospheric circulation.an.maly Precursor Telecon.ection.wave train

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Prob.otics in.erven.ion.in.colorectal can.er:From tradition.l approaches to n.vel strategies

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Chin.se Medical Journ.l 2024年第1期137卷 8-20页

作者： Suki ha Xian. Zhan. Jun.Yu In.titute of Digestive Disease an. Departmen. of Medicin. an. Therapeutics State Key Laboratory of Digestive DiseaseLi Ka Shing Institute of Health SciencesThe Chinese University of Hong KongHong Kong SARChina

The in.estin. harb.rs a large population.of microorgan.sms that in.eract with epithelial cells to main.ain.host healthy physiological *** in.estin.l microb.ota en.age in.the fermen.ation.of n.n.digestib.e n.trien.s an. produce b.n.ficial metab.lites to regulate host homeostasis,metab.lism,an. immun. *** disruption.of microb.ota,kn.wn.as dysb.osis,has b.en.implicated in.man. in.estin.l diseases,in.ludin. colorectal can.er(CRC).As the third most common.can.er an. the secon. leadin. cause of can.er-related death worldwide,CRC poses a sign.fican. health *** is an.urgen. n.ed for n.vel in.erven.ion. to reduce CRC in.iden.e an. improve clin.cal *** the in.estin.l microb.ota has emerged as a promisin. approach for CRC preven.ion.an. *** research efforts in.CRC prob.otics primarily focus on.reducin. the in.iden.e of CRC,alleviatin. treatmen.-related side effects,an. poten.iatin. the efficacy of an.ican.er therapy,which is the key to successful tran.lation.to clin.cal *** paper aims to review the tradition.l prob.otics an. n.w in.erven.ion.,such as n.xt-gen.ration.prob.otics an. postb.otics,in.the con.ext of *** un.erlyin. mechan.sms of prob.otic an.i-can.er effects are also discussed,in.ludin. the restoration.of microb.al composition.rein.orcemen. of gut b.rrier in.egrity,in.uction.of can.er cell apoptosis,in.ctivation.of carcin.gen.,an. modulation.of host immun. *** paper further evaluates the n.vel strategy of prob.otics as an.adjuvan. therapy in.b.ostin. the efficacy of chemotherapy an. *** all the promisin. fin.in.s presen.ed in.studies,the evaluation.of poten.ial risks,optimization.of delivery methods,an. con.ideration.of in.ra-patien. variab.lity of gut microb.al b.selin. must b. thoroughly in.erpreted b.fore b.n.h-to-b.dside tran.lation.

关键词： colorectal can.er prob.otics gut microb.ota dysb.osis adjuvan. therapy immun. modulation gut b.rrrier

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n.merical Simulation.of Thermocapillary Con.ection.with Evaporation.In.uced b. b.un.ary Heatin.

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Fluid Dyn.mics & Materials Processin. 2024年第7期20卷 1667-1686页

作者： O.n.Gon.harova V.b.b.kezhan.va Altai State Un.versity Institute of Mathematics and Information TechnologiesBarnaul656049Russia In.titute of Computation.l Modellin. Sb.RAS Department of Differential Equations of MechanicsKrasnoyarsk660036Russia

The dyn.mics of a b.layer system fillin. a rectan.ular cuvette sub.ected to extern.l heatin. is *** in.luen.e of two types of thermal exposure on.the flow pattern.an. on.the dyn.mic con.act an.le is *** particular,the cases of local heatin. from b.low an. distrib.ted thermal load from the lateral walls are *** simulation.is carried out within.the frame of a two-sided evaporative con.ection.model b.sed on.the b.ussin.sq approximation.A b.n.in.–air system is con.idered as referen.e *** variation.in.time of the con.act an.le is describ.d for b.th heatin. *** lateral heatin.,n.ar-wall b.un.ary layers emerge together with stron. con.ection.whereas the local thermal load from the lower wall results in.the formation.of multicellular motion.in.the en.ire volume of the fluids an. the appearan.e of tran.ition.regimes followed b. a steady-state *** results of the presen. study can.aid the design.of equipmen. for thermal coatin. or dryin. an. the developmen. of methods for the formation.of pattern. with required structure an. morphology.

关键词： Thermocapillary con.ection two-phase system n.merical modelin. con.act an.le

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Two un.elated Alagille syn.rome cases of South In.ian.origin.Showin. multi-exon.c deletion.an. a n.vel mutation.in.JAG1 gen.

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Gen.s & Diseases 2024年第3期11卷 66-68页

作者： Aswathi n.Jin.y M.Jose Sreelata b.n.ir Prab.a S.n.Pappachan.S Departmen. of Medical Gen.tics Lifeline Super Specialty HospitalPathanamthittaKerala 691523India Lifelin. Super Specialty Hospital PathanamthittaKerala 691523India

Alagille syn.rome(ALGS;OMIM#118450)is a highlyvariab.e,multi-systemic,autosomal domin.n. disorder,caused b. mutation. in.the Jagged Can.n.cal n.tch Ligan. 1(JAG1)gen.(20p12.2)or in.the n.urogen.c locus n.tch homolog protein.2(n.TCH2)gen.(1p13).^(1)It primarily affects the liver,heart,eyes,face,kidn.y,skin.verteb.ae,an. skeleton.^(1,2)The JAG1 gen. has 26 exon. an. ab.ut 90%of the ALGS cases result from pathogen.c varian.s in.the JAG1 an. aroun. 7%of cases have deletion. in.chromosome 20 that in.lude this gen..

关键词： JAG1 cases n.tch

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Astrophysical S-factor an. reaction.rate for 15n.p,γ)16O within.the modified poten.ial cluster model

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Chin.se Physics C 2024年第4期48卷 130-145页

作者： S.b.Dub.vichen.o A.S.Tkachen.o R.Ya.Kezerashvili n.A.b.rkova b.M.Yeleusheva Fesen.ov Astrophysical In.titute 050020 AlmatyKazakhstan n.w York City College of Techn.logy City University of New YorkBrooklyn11201 New YorkUSA Graduate School an. Un.versity Cen.er City University of New York10016 New YorkUSA al-Farab. Kazakh n.tion.l Un.versity 050040 AlmatyKazakhstan

We study radiative p^(15)n.capture on.the groun. state of ^(16)O at stellar en.rgies within.the framework of a modified poten.ial cluster model(MPCM)with forb.dden.states,in.ludin. low-lyin. *** in.estigation.of the ^(15)n.p,γ0)^(16)O reaction.in.ludes the con.ideration.of ^(3)S_(1) reson.n.es due to E1 tran.ition. an. the con.rib.tion.of the ^(3)P_(1) scatterin. wave in.the p+^(15)n.chan.el due to the ^(3)P_(1)→^(3)P_(0)M1 *** calculated the astrophysical low-en.rgy S-factor,an. the extrapolated S(0)turn.d out to b. within.34.7−40.4 keV·*** importan. role of the asymptotic con.tan.(AC)for the ^(15)n.p,γ0)16O process with in.erferin. ^(3)S_(1)(312)an. ^(3)S_(1)(962)reson.n.es is elucidated.A comparison.of our calculation.for the S-factor with existin. experimen.al an. theoretical data is addressed,an. a reason.b.e agreemen. is *** reaction.rate is calculated an. compared with the existin. *** has n.gligib.e depen.en.e on.the variation.of AC b.t shows a stron. impact of the in.erferen.e of ^(3)S_(1)(312)an. ^(3)S_(1)(962)reson.n.es in.referen.e to the Cn. Gamow win.ows,especially at low *** estimate the con.rib.tion.of cascade tran.ition. to the reaction.rate b.sed on.the exclusive experimen.al data from ***.C.85,065810(2012).The reaction.rate en.an.emen. due to the cascade tran.ition. is ob.erved from T_(9)>0.3 an. reaches the maximum factor~1.3 at T_(9)=*** presen. the Gamow en.rgy win.ow an. a comparison.of rates for radiative proton.capture reaction. ^(12)n.p,γ)^(13)O,^(13)n.p,γ)^(14)O,^(14)n.p,γ)^(15)O,an. ^(15)n.p,γ)^(16)O ob.ain.d in.the framework of the MPCM an. provide the temperature win.ows,prevalen.e,an. sign.fican.e of each process.

关键词： low an. astrophysical en.rgies p^(15)n.system thermon.clear reaction.rate poten.ial cluster model Cn.-cycle

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Direct microwave leachin. con.ition. of rare earth elemen.s in.fluorescen. wastes

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Journ.l of Rare Earths 2024年第6期42卷 1165-1174,I0007页

作者： A.b.len.b.b.rol M.n.Saridede S.S.Kaplan.M.S.Son.ez Departmen. of Metallurgical an. Materials En.in.erin. Yildiz Technical UniversityIstanbulTurkey Departmen. of Chemical En.in.erin. an. Materials Scien.e Stevens Institute of TechnologyNew JereyUSA Departmen. of Metallurgical an. Materials En.in.erin. Istanbul Technical UniversityIstanbulTurkey

The lumin.scen. phosphor powder in.the fluorescen. lamp con.titutes 2%of the lamp’s *** can.b. men.ion.d that fluorescen. wastes are a crucial raw material to produce rare earth *** the presen. study,microwave leachin. process was con.ucted to dissolve rare earth elemen.s yttrium(Y),europium(Eu),an. remain.n. rare earth elemen.s(REEs)presen. in.the phosphor powder of the fluorescen. *** the yields were *** the microwave leachin. process,the effects of the temperature(80-160℃),acid type(hydrochloric acid(HCl),n.tric acid(Hn._(3)),sulphuric acid(H_(2)SO_(4))),acid con.en.ration.0.5-6 mol/L),solid to liquid ratio(0.1:10-0.5:10)an. reaction.time(5-90 min.parameters on.leachin. efficien.ies of varyin. rare earth elemen.s an. calcium were *** highest yield was ob.ain.d in.the direct microwave leachin. of fluorescen. waste with the experimen.al con.ition. of 6 mol/L HCl,160℃,0.1:10 solid-to-liquid ratio(S:L),an. 90 *** en.rgy calculation. were made,an. kin.tic models of the reaction. were ob.ain.d,an. it is ob.erved that Y an. Eu dissolution.is diffusion.con.rolled,on.the other han.,lan.han.m(La),cerium(Ce),an. terb.um(Tb.were examin.d to b. chemical reaction.***,calcium(Ca)an. gadolin.um(Gd)seem coheren. with the mixed ***,mathematical models of all experimen.al studies are created with the respon.e surface b.x-b.hn.en.method an. the correlation.coefficien.s of all the models are over 90%.

关键词： Rare earth elemen.s(REEs) Direct microwave leachin. Fluorescen. waste Kin.tic models Respon.e surface method

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Further Studies of the Cap Pushin. Respon.e in.Hon.y b.es (Apis mellifera)

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n.tural Scien.e 2024年第5期16卷 45-64页

作者： Riley J. Win.heski Kiri Li n. Stauch Laura M. Grossn.r Maya b. Zepeda James W. Grice Charles I. Ab.amson Departmen. of Psychology Oklahoma State University Stillwater USA Lab.ratory of Comparative Psychology an. b.havioral b.ology Oklahoma State University Stillwater USA Departmen. of Earth an. En.iron.en.al Scien.es California State University Fresno USA

The Cap Pushin. Respon.e (CPR) is a free-flyin. techn.que used to study learn.n. an. memory in.hon.y b.es (Apis mellifera). The series of experimen.s outlin.d in.this paper aimed to test whether hon.y b.es exhib.t the cogn.tive con.ept of “expectan.y” utilizin. the CPR in.a weight differen.iation.paradigm. Five previous experimen.s in.our lab.ratory have explored whether the con.ept of expectan.y can.accoun. for hon.y b.e performan.e an. have all failed to support the cogn.tive in.erpretation. The first experimen. examin.d if b.es could differen.iate b.tween.the two caps in.the amoun. of force they used to push the cap an. the distan.e the cap was pushed when.the caps were presen.ed on. at a time. The secon. experimen. explored cap weight preferen.e b. presen.in. b.es with a choice b.tween.the two caps. The third an. fourth experimen.s tested the b.e’s ab.lity to expect reward or pun.shmen. b.sed on.cap weight. Results revealed that b.es were foun. to have a stron. preferen.e for the light cap an. therefore were n.t ab.e to expect reward or pun.shmen. b.sed on.cap weight. These experimen.s con.rib.te to the deb.te on.whether b.es have “cogn.tive” represen.ation. an. con.in.e to support the b.haviorist in.erpretation.

关键词： Apis mellifera Cap Pushin. Respon.e Cogn.tion Learn.n.

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b.ockade of Rho-associated kin.se preven.s in.ib.tion.of axon.regen.ration.of peripheral n.rves in.uced b. an.i-gan.lioside an.ib.dies

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n.ural Regen.ration.Research 2024年第4期19卷 895-899页

作者： An.rés b.rardo Cristian.R.b.caglio b.rb.ra b.b.ez Rub.n.Samb.elli Kazim A.Sheikh Pab.o H.H.Lopez Lab.ratorio de n.urob.ología Instituto de Investigación Médica Mercedes y Martin Ferreyra(INIMEC)-Consejo Nacional de Investigaciones Cientificas y Técnicas(CONICET)Universidad Nacional de Córdoba Departamen.o de Química b.ológica-Cen.ro de In.estigacion.s en.Química b.ológica de Córdob.(CIQUIb.C)-Con.ejo n.cion.l de In.estigacion.s Cien.ificas y Técn.cas(COn.CET) Facultad de Cs.QuímicasUniversidad Nacional de Córdoba Servicio de An.tomía Patológica Clínica Universitaria Reina FabiolaUniversidad Católica de Córdoba Departmen. of n.urology University of Texas Medical School at Houston

An.i-gan.lioside an.ib.dies are associated with delayed/poor clin.cal recovery in.Guillain.b.rrèsyn.rome,mostly related to halted axon.***-lin.in. of cell surface gan.liosides b. an.i-gan.lioside an.ib.dies triggers in.ib.tion.of n.rve repair in.in.vitro an. in.vivo paradigms of axon.*** effects in.olve the activation.of the small GTPase Rho A/ROCK sign.lin. pathways,which n.gatively modulate growth con. cytoskeleton.similarly to well stab.ished in.ib.tors of axon.regen.ration.describ.d so *** aim of this work was to perform a proof of con.ept study to demon.trate the effectiven.ss of Y-27632,a selective pharmacological in.ib.tor of ROCK,in.a mouse model of axon.regen.ration.of peripheral n.rves,where the passive immun.zation.with a mon.clon.l an.ib.dy targetin. gan.liosides GD1a an. GT1b.was previously reported to exert a poten. in.ib.tory effect on.regen.ration.of b.th myelin.ted an. un.yelin.ted *** results demon.trate a differen.ial sen.itivity of myelin.ted an. un.yelin.ted axon. to the pro-regen.rative effect of *** with a total dosage of 9 mg/kg of Y-27632 resulted in.a complete preven.ion.of an.i-GD1a/GT1b.mon.clon.l an.ib.dy-mediated in.ib.tion.of axon.regen.ration.of un.yelin.ted fib.rs to skin.an. the fun.tion.l recovery of mechan.cal cutan.ous *** con.rast,the same dose showed toxic effects on.the regen.ration.of myelin.ted ***,scale down.of the dosage of Y-27632 to 5 mg/kg resulted in.a sign.fican. although n.t complete recovery of regen.rated myelin.ted axon. exposed to an.i-GD1a/GT1b.mon.clon.l an.ib.dy in.the ab.en.e of toxicity in.an.mals exposed to on.y ***,these fin.in.s con.irm the in.vivo participation.of Rho A/ROCK sign.lin. pathways in.the molecular mechan.sms associated with the in.ib.tion.of axon.regen.ration.in.uced b. an.i-GD1a/GT1b.mon.clon.l *** fin.in.s open.the possib.lity of therapeutic pharmacological in.erven.ion.targetin. Rho A/R

关键词： an.i-gan.lioside an.ib.dies an.i-glycan.an.ib.dies axon.regen.ration gan.lioside Guillain.b.rrésyn.rome n.rve repair ROCK Y-27632

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Quasi-on. dimen.ion.l n.n.dots of Au pattern.d b. hierarchical self-assemb.y

Quasi-one dimensional nanodots of Au patterned by hierarchic...

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第18届国际真空大会

作者： J. H. Kim n.-b. ha M. Joe K.-L. Lee R. Cuern. J.-S. Kim Departmen. of Physics Sookmyung Women's University Computation.l Scien.e Cen.er Korea Institute of Science and Technology Departamen.o de Matematicas an. Group In.erdisciplin.r de Sistemas Complejos (GISC) Universidad Carlos Ⅲ de Madrid

Curren.ly periodic arrays of n.n.structure have drawn.exten.ive atten.ion.due to their poten.ial for various application. such as catalysts, sen.ors an. photon.cs. Ion.b.am sputterin. （Ib.） is a promisin. can.idate for fab.ication.of highly ordered n.n.structures in.self-organ.zed fashion. allowin. for easy, low-cost an. large area fab.ication.of n.n.structures on.various materials.

关键词： hierarchical self-assemb.y ion.b.am sputterin. redeposition n.n.in.ar cKPZ

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Malign.n. triton.tumor in.the ab.omin.l wall:A case report

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World Journ.l of Clin.cal Cases 2024年第8期12卷 1467-1473页

作者： Ho Jik Yan. Don.hyun.Kim Won.Suk Lee San.-ha Oh Departmen. of Plastic an. Recon.tructive Surgery Chungnam National University Sejong HospitalSejong 30099South Korea Departmen. of Plastic an. Recon.tructive Surgery Chungnam National University HospitalDaejeon 35015South Korea Departmen. of Emergen.y Eulji University HospitalDaejeon 35233South Korea Departmen. of Plastic an. Recon.tructive Surgery Chungnam National University College of MedicineDaejeon 35015South Korea

b.CKGROUn. Malign.n. triton.tumors(MTTs)comprise a sub.roup of malign.n. peripheral n.rve sheath tumors(MPn.Ts)that exhib.ts rhab.omyosarcomatous differen.tiation.an. follow an.aggressive *** are primarily located alon. peripheral *** of MTTs in.the ab.omin.l wall have n.t b.en.*** has a poorer progn.sis than.classic MPn.Ts,an. accurate diagn.sis n.cessitates a keen.un.erstan.in. of the clin.cal history an. kn.wledge of its differen.ial diagn.sis *** for MTTs mirrors that for MPn.Ts an. is predomin.n.ly *** SUMMARY A 49-year-old woman.presen.ed with a sub.utan.ous mass in.her lower ab.o-min.l wall an. a pre-existin. surgical scar that had grown.slowly over 3-4 mon.hs b.fore the *** had previously un.ergon. radical hysterectomy an. con.urren. chemo-radiotherapy for cervical can.er approximately 5 years prior to the *** computed tomography(CT)showed a 1.3 cm midlin. mass in.the lower ab.omen.with in.iltration.in.o the rectus ab.omin.s *** was n. sign.of metastasis(T1n.M0).An.in.ision.l b.opsy iden.ified sporadic MTT of the lower ab.omen.A comprehen.ive surgical excision.with a 3 cm margin.in.lusive of the periton.um was ***-quen.ly,the gen.ral surgeon.utilized an.approach akin.to the open.periton.al on.ay mesh *** patien. un.erwen. addition.l treatmen. with an.excision.shaped as a min.-ab.omin.plasty for the skin.*** complication. arose,an. an.ual follow-up CTs did n.t show sign. of recurren.e or *** An.ab.omin.l MTT was efficaciously treated with exten.ive excision.an. ab.omin.l wall recon.truction.elimin.tin. the n.ed for postoperative radiotherapy.

关键词： Malign.n. triton.tumor Ab.omin.l wall Surgical excision Recon.truction Case report

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