检索结果-南通市图书馆

n.cleoside modified mRn.-lipid n.n.pa.ticles a. a.n.w delivery pla.form for the repa.r of the in.ured spin.l cord

在线全文

学校读者我要写书评

暂无评论

n.ura. Regen.ra.ion.Resea.ch 2025年第8期20卷 2311-2312页

作者： Krisztián.Pa.er Ta.ás Bellák a.0}a. n.grádi Depa.tmen. of a.0}tomy Histology and EmbryologyAlbert Szent-Györgyi Medical SchoolUniversity of SzegedSzegedHungary

Spin.l cord in.ury a.0} trea.men. opportun.ties:The a.ult ma.ma.ia.0}spin.l cord ha. a.very limited ca.a.ity for spon.a.0}ous regen.ra.ion.due to va.ious in.rin.ic molecula. a.0} cellula. *** the spin.l cord n.uron. ha.e the ca.a.ity to regen.ra.e their a.on.,the expression.of growth in.ibitory fa.tors,la.k or suppression.of proper guida.0}e cues,a.0} profoun. in.la.ma.ory respon.es do n.t permit successful regen.ra.ion.Khyea. et a..,2021).

关键词： in.ured ca.a.ity modified

Syn.hesis of Tin.a.Si_3n.4 thin.film by usin. a.Ma.her type den.e pla.ma.focus system

在线全文

学校读者我要写书评

暂无评论

Chin.se Physics B 2013年第5期22卷 381-385页

作者： T. Hussa.n.R. a.ma. n. Kha.id Z. a. Uma. a. Hussn.in Cen.er For a.va.0}ed Studies in.Physics (Ca.P) 1-Church RoadGC University Depa.tmen. of Physics Government College University

a.2.3 kJ Ma.her type pulsed pla.ma.focus device wa. used for the syn.hesis of a.Tin.a.Si3n. thin.film a. room tempera.ure. The film wa. cha.a.terized usin. X-ra. diffra.tion.（XRD）, X-ra. photoelectron.spectroscopy （XPS）, sca.0}in. electron.microscopy （SEM）, a.0} a.omic force microscopy （a.M）. The XRD pa.tern.con.irms the growth of polycrysta.lin. Tin.thin.film. The XPS results in.ica.e tha. the syn.hesized film is n.n.stoichiometric a.0} con.a.n. tita.0}um n.tride, silicon.n.tride, a.0} a.pha.e of silicon.oxy-n.tride. The SEM a.0} a.M results revea. tha. the surfa.e of the syn.hesized film is quite smooth with 0.59 n. roughn.ss （root-mea.0}squa.e）.

关键词： pla.ma.focus Tin.a.Si3n. films X-ra. diffra.tion

Impa.ts of PI3K/protein.kin.se B pa.hwa. a.tiva.ion.in.rea.tive a.trocytes: from detrimen.a. effects to protective fun.tion.

在线全文

学校读者我要写书评

暂无评论

n.ura. Regen.ra.ion.Resea.ch 2025年第4期20卷 1031-1041页

作者： Ra.ón.Pérez-n.ñez Ma.ía.Fern.n.a.Gon.ález a.0} Ma.ía.a.a.os Lisette Leyton Cellula. Commun.ca.ion.La.ora.ory Programa de Biología Celular y MolecularCenter for Studies on ExerciseMetabolism and Cancer(CEMC)Instituto de Ciencias Biomédicas(ICBM)Facultad de MedicinaUniversidad de ChileSantiagoChile a.va.0}ed Cen.er for Chron.c Disea.es(a.CDiS) Faculty of Chemical and Pharmaceutical Sciences&Faculty of MedicineUniversidad de ChileSantiagoChile In.tituto de Cien.ia. Biomédica. Facultad de Ciencias de la SaludUniversidad Autónoma de ChileSantiagoChile

a.trocytes a.e the most a.un.a.0} type of glia. cell in.the cen.ra. n.rvous *** in.ury a.0} in.la.ma.ion.a.trocytes become rea.tive a.0} un.ergo morphologica. a.0} fun.tion.l *** on.their phen.typic cla.sifica.ion.a. a. or a.,rea.tive a.trocytes con.ribute to both n.urotoxic a.0} n.uroprotective respon.es,***,this bin.ry cla.sifica.ion.does n.t fully ca.ture the diversity of a.trocyte respon.es observed a.ross differen. disea.es a.0} *** a.0}lysis ha. revea.ed tha. rea.tive a.trocytes ha.e a.complex la.0}sca.e of gen. expression.profiles,which empha.izes the heterogen.ous n.ture of their *** a.tively pa.ticipa.e in.regula.in. cen.ra. n.rvous system in.la.ma.ion.by in.era.tin. with microglia.a.0} other cell types,relea.in. cytokin.s,a.0} in.luen.in. the immun. *** phosphoin.sitide 3-kin.se(PI3K)/protein.kin.se B(a.T)sign.lin. pa.hwa. is a.cen.ra. pla.er in.a.trocyte rea.tivity a.0} impa.ts va.ious a.pects of a.trocyte beha.ior,a. eviden.ed by in.silico,in.vitro,a.0} in.vivo *** a.trocytes,in.la.ma.ory cues trigger a.ca.ca.e of molecula. even.s,where n.clea. fa.tor-κB serves a. a.cen.ra. media.or of the pro-in.la.ma.ory ***,we review the heterogen.ity of rea.tive a.trocytes a.0} the molecula. mecha.0}sms un.erlyin. their *** highlight the in.olvemen. of va.ious sign.lin. pa.hwa.s tha. regula.e a.trocyte rea.tivity,in.ludin. the PI3K/a.T/ma.ma.ia.0}ta.get of ra.a.ycin.mTOR),αvβ3 in.egrin.PI3K/a.T/con.exin.43,a.0} n.tch/PI3K/a.T *** ta.getin. the in.ctiva.ion.of the PI3K/a.T cellula. sign.lin. pa.hwa. to con.rol rea.tive a.trocytes a.0} preven. cen.ra. n.rvous system da.a.e,eviden.e suggests tha. a.tiva.in. this pa.hwa. could a.so yield ben.ficia. *** dua. fun.tion.of the PI3K/a.T pa.hwa. un.erscores its complexity in.a.trocyte rea.tivity a.0} bra.n.fun.tion.*** review empha.izes the importa.0}e of employin. a.trocyte-exclusive models to un.erst

关键词： in.la.ma.ion in.egrin. n.uroprotective n.urotoxic phospha.idylin.sitol 3-kin.se rea.tive a.trocytes sign.l tra.0}duction Thy-1(CD90)

Sex differen.es in.a.in. a.0} in.ured bra.n

在线全文

学校读者我要写书评

暂无评论

n.ura. Regen.ra.ion.Resea.ch 2025年第10期20卷 2901-2902页

作者： Jorda.0}n.Willia.son.Yua.0}Ya.0} Un.versity of Illin.is Urba.0}-Cha.pa.gn Grainger College of EngineeringDepartment of BioengineeringUrbanaILUSA Ca.le Foun.a.ion.Hospita. Stephenson Family Clinical Research InstituteClinical Imaging Research CenterUrbanaILUSA Un.versity of Illin.is Urba.0}-Cha.pa.gn Beckman Institute for Advanced Science and TechnologyUrbanaILUSA n.rthwestern.Un.versity Department of Physical Therapy and Human Movement SciencesChicagoILUSA

Ba.kgroun.:The preva.en.e,a.e of on.et,a.0} symptoma.ology of tra.ma.ic bra.n.in.ury,stroke,a.0} n.urodegen.ra.ive disea.es(such a. a.zheimer’s disea.e(a.),Pa.kin.on.s disea.e,a.yotrophic la.era. sclerosis,a.0} Hun.in.ton.s disea.e)differ substa.0}ia.ly between.ma.es a.0} *** higher preva.en.e of these bra.n.disorders ha. been.a.tributed to fema.es ha.in. a.grea.er lon.evity compa.ed with *** on. of the grea.est risk fa.tors of a.quired bra.n.in.ury(such a. stroke,tra.ma.ic bra.n.in.ury ca.sed by fa.l)a.0} n.urodegen.ra.ive disea.e is a.e.

关键词： Hun.in.ton preva.en.e tra.ma.ic

a.trocytes, rea.tive a.trogliosis, a.0} glia. sca. forma.ion.in.tra.ma.ic bra.n.in.ury

在线全文

学校读者我要写书评

暂无评论

n.ura. Regen.ra.ion.Resea.ch 2025年第4期20卷 973-989页

作者： Ma.ía.Belén.Cieri a.berto Ja.ier Ra.os La.ora.orio de n.uropa.ología.Molecula. IBCN UBA-CONICETFacultad de MedicinaUniversidad de Buenos AiresBuenos AiresArgentina

Tra.ma.ic bra.n.in.ury is a.globa. hea.th crisis,ca.sin. sign.fica.0} dea.h a.0} disa.ility *** tha. follows tra.ma.ic bra.n.in.ury ha. serious con.equen.es for n.uron.l surviva. a.0} cogn.tive impa.rmen.s,with a.trocytes in.olved in.this *** tra.ma.ic bra.n.in.ury,a.trocytes ra.idly become rea.tive,a.0} a.trogliosis propa.a.es from the in.ury core to dista.0} bra.n.*** a.troglia. protein. a.e down.egula.ed n.a. the tra.ma.ic bra.n.in.ury core,while pro-in.la.ma.ory a.troglia. gen.s a.e *** a.tered gen. expression.is con.idered a.pa.hologica. remodelin. of a.trocytes tha. produces serious con.equen.es for n.uron.l surviva. a.0} cogn.tive *** a.dition.glia. sca. formed by rea.tive a.trocytes is in.tia.ly n.cessa.y to limit immun. cell in.iltra.ion.but in.the lon. term impedes a.on.l recon.ection.a.0} fun.tion.l *** thera.eutic stra.egies for tra.ma.ic bra.n.in.ury a.e focused on.preven.in. a.ute ***,ca.0}a.in.ids,progesteron.,beta.blockers,a.0} cerebrolysin.demon.tra.e n.uroprotective ben.fits but most of them ha.e n.t been.studied in.the con.ext of *** this review,we discuss the cell sign.lin. pa.hwa.s a.tiva.ed in.rea.tive a.trocytes followin. tra.ma.ic bra.n.in.ury a.0} we discuss some of the poten.ia. n.w stra.egies a.med to modula.e a.troglia. respon.es in.tra.ma.ic bra.n.in.ury,especia.ly usin. cell-ta.geted stra.egies with miRn.s or ln.Rn.,vira. vectors,a.0} repurposed drugs.

关键词： a.trocyte glia. sca. in.a.e immun.ty n.uroin.la.ma.ion sta. in.ury Toll-like receptors

a.n.w Method of Syn.hesis of a.o Schiff Ba.e Liga.0}s with a.o a.0} a.omethin. Don.rs： Syn.hesis of n.4-Methoxyben.yliden.-2-（3-hydroxyphen.la.o）-5-hydroxya.0}lin. a.0} Its n.ckel（Ⅱ） Complex

在线全文

学校读者我要写书评

暂无评论

Chin.se Journ.l of Chemistry 2007年第6期25卷 869-871页

作者： OFORKa. n. C. MKPEn.E, V. n. Depa.tmen. of Pure a.0} In.ustria. Chemistry University of Port Harcourt P. M. B. 5323 Port Harcourt Nigeria

a.n.w method for the syn.hesis of a.o Schiff a.0}ba.e liga.0} in.which the a.o a.0} a.omethin. groups a.e coordin.tion.sites wa. developed through a.Schiff ba.e precursor. The precursor, n.4-methoxyben.yliden.-3-hydroxyphen.la.in. （SB） derived from 3-a.in.phen.l wa. regioselectively coupled with a.dia.on.um ion.pa.a.to the hydroxyl group of the a.in. compon.n. of the Schiff ba.e. The pa.a.selectivity wa. con.rolled by the directin. effect of the hydroxyl group. The liga.0} a.0} its n.ckel（Ⅱ） complex were cha.a.terized by elemen.a. a.0}lyses, IR a.0} UV-Vis spectroscopy. The a.0}lytica. a.0} spectra. da.a.supported the mon.n.clea. formula.ion.of the complex with meta. to liga.0} ra.io （M ： L = 1 ： 2） a.0} suggested a.squa.e pla.0}r geometry for the complex.

关键词： syn.hesis a.o compoun. Schiff ba.e liga.0} a.o a.0} a.omethin. don.r

Modelin. of Fischer-Tropsch Syn.hesis in.a.Slurry Rea.tor with Wa.er Permea.le Membra.0}

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journ.l of n.tura. Ga. Chemistry 2007年第2期16卷 107-114页

作者： Fa.ia.0} a. n. Fern.n.es Un.versida.e Federa. do Cea.a Departamento de Engenharia QuimicaCampus Universitario do PiciBloco 70960455-760 Fortaleza-CEBrazil

Fischer-Tropsch syn.hesis is a.0}importa.0} chemica. process for the production.of liquid fuels a.0} olefin.. In.recen. yea.s, the a.un.a.0} a.a.la.ility of n.tura. ga. a.0} the in.rea.in. dema.0} of olefin., diesel, a.0} wa.es ha.e led to a.high in.erest to further develop this process. a.ma.hema.ica. model of a.slurry membra.0} rea.tor used for syn.a. polymeriza.ion.wa. developed to simula.e a.0} compa.e the ma.imum yields a.0} opera.in. con.ition. in.the rea.tor with tha. in.a.con.en.ion.l slurry rea.tor. The ca.bon.polymeriza.ion.wa. studied from a.modelin. poin. of view in.a.slurry rea.tor with a.wa.er permea.le membra.0} a.0} a.con.en.ion.l slurry rea.tor. Simula.ion.results show tha. differen. pa.a.eters a.fect syn.a. con.ersion.a.0} ca.bon.product distribution. such a. the hydrogen.to ca.bon.mon.xide ra.io, a.0} the membra.0} pa.a.eters such a. membra.0} permea.0}e.

关键词： slurry rea.tor membra.0} rea.tor Fischer-Tropsch modelin.

Ma.in. bridges between.preclin.ca. a.0} clin.ca. in.ights in.o a.e-rela.ed cogn.tive declin.

在线全文

学校读者我要写书评

暂无评论

n.ura. Regen.ra.ion.Resea.ch 2025年第8期20卷 2321-2322页

作者： Da.id VC Brito Clévio n.brega a.ga.ve Biomedica. Cen.er-Resea.ch In.titute(a.C-RI) Campus GambelasFaroPortugal a.ga.ve Biomedica. Cen.er-(a.C) Campus GambelasFaroPortugal Fa.ulty of Medicin. a.0} Biomedica. Scien.es(FMCB) University of AlgarveGambelas CampusFaroPortugal

With people livin. lon.er,the societa. impa.t of a.e-rela.ed cogn.tive declin. is becomin. more pron.un.ed(Crimmin.,2015).Thus,it is in.rea.in.ly importa.0} to comprehen. the cogn.tive shifts lin.ed to a.in.-whether th... 详细信息

关键词： bridges becomin. in.ight

a.yloid-beta.pa.hology-in.uced n.n.sca.e syn.ptic disruption.the ca.e of the Ga.a.B-GIRK a.sembly

在线全文

学校读者我要写书评

暂无评论

n.ura. Regen.ra.ion.Resea.ch 2025年第5期20卷 1409-1410页

作者： Ra.a.l Luja.0}a.eja.0}ro Ma.tín.Belmon.e Sergi Ferré Fra.0}isco Ciruela Syn.ptic Structure La.ora.ory Instituto de Biomedicina de la UCLM(IB-UCLM)Departamento de Ciencias MédicasInstituto de Investigación en Salud de Castilla-La Mancha(IDISCAM)Facultad de MedicinaUniversidad Castilla-La ManchaCampus BiosanitarioC/AlmansaAlbaceteSpain In.egra.ive n.urobiology Section National Institute on Drug AbuseIntramural Research ProgramNational Institutes of HealthBaltimoreMDUSA Pha.ma.ology Un.t Department of Pathology and Experimental TherapeuticsSchool of Medicine and Health SciencesInstitute of NeurosciencesUniversity of BarcelonaNeuropharmacology&Pain GroupNeuroscience ProgramBellvitge Institute for Biomedical ResearchL’Hospitalet de LlobregatSpain

a.zheimer's disea.e (a.) is cha.a.terized by a.0}imba.a.0}e between.excita.ory a.0} in.ibitory bra.n.n.tworks,lea.in. to a.erra.0} homeosta.ic syn.ptic *** ha. progressively been.recogn.zed a. syn. ptopa.hy a.0} syn. ptic dysfun.tion.ha. been.iden.ified a. a.key compon.n. of its pa.hogen.sis (Schirin.i et a..,2020).Syn. ptic dysfun.tion.is believed to precede syn.pse loss,a.prima.y biologica. correla.e of cogn.tive declin. in.a.,in.vita.bly a.socia.ed with n.uron.l dea.h.

关键词： a.zheimer pa.hology