Nucleoside modified mRNA-lipid nanoparticles as a new delivery platform for the repair of the injured spinal cord
作者机构:Department of AnatomyHistology and EmbryologyAlbert Szent-Györgyi Medical SchoolUniversity of SzegedSzegedHungary
出 版 物:《Neural Regeneration Research》 (中国神经再生研究(英文版))
年 卷 期:2025年第20卷第8期
页 面:2311-2312页
核心收录:
学科分类:1002[医学-临床医学] 100210[医学-外科学(含:普外、骨外、泌尿外、胸心外、神外、整形、烧伤、野战外)] 10[医学]
摘 要:Spinal cord injury and treatment opportunities:The adult mammalian spinal cord has a very limited capacity for spontaneous regeneration due to various intrinsic molecular and cellular *** the spinal cord neurons have the capacity to regenerate their axons,the expression of growth inhibitory factors,lack or suppression of proper guidance cues,and profound inflammatory responses do not permit successful regeneration(Khyeam et al.,2021).