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CBCT评估不同矢状骨面型上颌后牙牙根与上颌窦底的关系

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CBCT评估不同矢状骨面型上颌后牙牙根与上颌窦底的关系

作者： dia Ayyash 大连医科大学

学位级别：硕士

目的:本研究主要目的是评估不同骨性错(牙合)畸形上颌窦底与后牙牙根的邻近关系,因此,我们可以知道上颌后牙根在哪种骨型中更靠近上颌窦底,为正畸治疗计划提供参考。材料与方法:选择大连医科大学附属第二医院60名成人{20-35岁}中国正畸... 详细信息

目的:本研究主要目的是评估不同骨性错(牙合)畸形上颌窦底与后牙牙根的邻近关系,因此,我们可以知道上颌后牙根在哪种骨型中更靠近上颌窦底,为正畸治疗计划提供参考。材料与方法:选择大连医科大学附属第二医院60名成人{20-35岁}中国正畸患者,根据AnB角度,将患者分为三组:骨性Ⅰ类错(牙合)(n=20),骨性II类错(牙合)(n=20),骨性Ⅲ类错(牙合)(n=20)。在CBCT扫描中从侧面和冠状视图分析每个上颌后牙根尖与上颌窦底之间的垂直关系。为了获得更准确的结果,使用两种不同的计算机软件(i CATVision,Invivo5)对牙根进行了两次检查。根据牙根与上颌窦底关系,对双侧上颌第一、第二前磨牙和磨牙进行评分(得分0-3):(0分)牙根远离窦皮质边缘,其间有松质骨区;(1分)牙根部横向投射远离窦的皮质边缘;(2分)牙根尖与上颌窦底皮质边界接触;(3)牙根尖位于上颌窦内。计算每位患者每颗牙齿的平均得分,分析性别,年龄,骨型,左右两侧和FMA角度对每位患者和牙齿平均得分的影响。结果:骨性Ⅲ类错(牙合)受试者的每位患者平均得分明显着高于骨性I类错(牙合)受试者(P=.025),骨性Ⅲ类错(牙合)受试者的平均得分明显着高于骨性II类错(牙合)受试者(P=.007),骨性I类错(牙合)受试者和骨性II类错(牙合)受试者之间无统计学差异(P=.603),表明骨性Ⅲ类错(牙合)受试者比骨性I类和II类错(牙合)受试者,其根尖更接近上颌窦底。不同骨性错(牙合)之间第一磨牙的牙齿评分平均值存在统计学差异,表明骨性Ⅲ类和I类错(牙合)以及骨性Ⅲ类和II类错(牙合)之间的平均差异具有统计学意义(分别为P=.008和.007)。骨性I类和II类错(牙合)之间无统计学差异(P值=.955)。骨性Ⅲ类错(牙合)与骨性Ⅱ类、骨性Ⅰ类患者相比,其上颌第一磨牙牙根进入上颌窦内者明显多于骨性I类和II类错(牙合)。患者评分平均值在性别,年龄,及FMA角之间P值分别为0.222、0.949、0.356,P值>0.05无统计学差异。结论:正畸医师在设计治疗计划时,通常会考虑患者骨上下颌骨矢状性关系和口颌功能情况。尤其在压低或整体移动上颌后牙通过上颌窦底时候会引起不同程度根尖吸收,因此必须更加注意上颌后牙根尖与上颌窦底之间的关系。因为上颌窦的特殊解剖特征,上颌后牙的牙根经常进入上颌窦,导致该区域牙齿移动困难。因而,研究上颌后牙牙根与上颌窦的关系,关于正畸诊断和治疗方案设计、与控制牙齿垂直向移动非常重要。结果显示,在成人(20-35岁)正常垂直骨面型中(均角FMA 22°8°)上颌后牙根与上颌窦底的临近关系与骨性错(牙合)有关。与I类和II类骨性错(牙合)相比,在骨性Ⅲ类错(牙合)中上颌后牙的牙根更接近上颌窦底。骨性Ⅲ类错(牙合)患者上颌第一磨牙牙根较骨性Ⅱ类和Ⅰ类错(牙合)患者更接近上颌窦底。性别对上颌后牙牙根与上颌窦底的距离没有影响。

关键词：上颌窦骨性错(牙合) CBCT

Impact of simulated in vitro gastrointestinal digestion on bioactive compounds,bioactivity and cytotoxicity of melon (Cucumis melo L. inodorus) peel juice powder

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Food Bioscience 2022年第3期47卷 1358-1367页

作者： Ricardo Gómez-García Ana A.Vilas-Boas Manuela Machado Débora A.campos Cristóbal n.Aguilar Ana R.Madureira Manuela Pintado Universidade Católica Portuguesa CBQF-Centro de Biotecnologia e Química Fina – Laboratório AssociadoEscola Superior de BiotecnologiaRua Diogo Botelho 13274169-005PortoPortugal BBG-dia.Bioprocesses and Bioproducts Group.Food Research Department School of ChemistryAutonomous University of CoahuilaSaltilloCoahuilaMexico

The objectives of this research work were to evaluate the effect of in vitro gastrointestinal digestion (GIT) on melon peel juice (MPJ) powder from fruit processing industry by-products,considering (i) the recovery and accessibility indexes,(ii) the changes on antioxidant activity,and (iii) the prebiotic *** exposition to GIT conditions a decrease on the total phenolic content (TPC = 65.31%) and antioxidant activity by ABTS = 39.77% and DPPH = 45.91% were ***,these both parameters exhibited stable accessibility,accounting with 81.89%,76.55%,and 54.07% for TPC,ABTS and DPPH,*** gastrointestinal digestion,the non-absorbed fraction exhibited a positive impact on the growth of Bifidobacterium and Lactobacillus strains,possibly associated with the high content of simple sugar (glucose and fructose).This fraction also showed to be safe on Caco-2 intestinal *** findings suggest that MPJ might be used as a potential food functional ingredient.

关键词： Melon by-products Functional ingredients Phenolic antioxidants Simulated digestion Prebiotic effect

陆地棉二个正反交组合农艺和纤维品质性状的QTL分析

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陆地棉二个正反交组合农艺和纤维品质性状的QTL分析

作者： Souleymane dia 中国农业科学院

学位级别：硕士

棉花是主要的天然纤维,通常栽培的是陆地棉。由于产量的不稳定,纤维质量下降和极端环境(生物胁迫和非生物胁迫)的增多,世界棉花产业变得越来越脆弱。为了扭转这种局面,育种家采用常规育种和分子育种并行的手段,然而他们依然面临以下两... 详细信息

棉花是主要的天然纤维,通常栽培的是陆地棉。由于产量的不稳定,纤维质量下降和极端环境(生物胁迫和非生物胁迫)的增多,世界棉花产业变得越来越脆弱。为了扭转这种局面,育种家采用常规育种和分子育种并行的手段,然而他们依然面临以下两个障碍：现代栽培棉品种间狭窄的遗传距离和陆地棉纤维品质与其它农艺性状的显著负相关。由于这些决定经济价值的纤维性状呈数量遗传规律,因而确定与这些性状相关的基因显得尤为重要。数量性状位点(QTL)的定位和应用对改良产量和纤维品质,加速整个棉花育种进程具有重要意义。QTL需要利用作图群体结合特殊的标记(通常为分子标记)确定群体每个个体的基因型,构建连锁图,遗传图谱的构建通常与传统的孟德尔遗传规律存在偏差,这种现象称为偏分离。另外一个值得关注是我们考察的性状在杂交群体中的偏离方向或潜在的母本效应。本研究利用一个高衣分材料(A971)和两个低衣分但是具有优异纤维品质(R4121和J02-508)的材料进行正反交,形成4个F2群体,每个群体包含279个单株。其中J02-508具有异常棉(Gossypium anomalum)的血缘。本研究调查了4个农艺性状(铃数、籽棉产量、皮棉重和衣分)和5个纤维品质性状(纤维长度、纤维强度、纤维伸长率、马克隆值和纤维整齐度)。结果表明铃数、衣分、纤维长度和纤维伸长率呈现负超亲分离,而纤维整齐度和马克隆值呈现出正超亲分离。除衣分之外所有性状在正交和反交至少一个群体中母本效应表现出显著的差异,而在所有正反交群体中,铃数表现出极显著的差异(pnGR5503和MOnGR6128分别和衣分、纤维长度和纤维强度关联,这些标记可以用于未来的分子育种中。另外,本研究发现正反交会影响农艺性状和纤维品质性状和偏分离趋势。

关键词：陆地棉正反交 SSR 偏分离 QTL 农艺性状纤维品质

产品和促销相关活动对塞内加尔电信公司市场份额的影响

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产品和促销相关活动对塞内加尔电信公司市场份额的影响

作者： Khadija dia 东北财经大学

学位级别：硕士

自从过去几年中促进互联网可访问性以来,与互联网有关的活动和手机的使用一直在蓬勃发展。关于电信,根据(AnSD),塞内加尔对技术和金融资源进行了大量投资,因为它为经济增长做出了 4.72%的贡献,并代表了国家计划中最重要的计划之一,即PSE... 详细信息

自从过去几年中促进互联网可访问性以来,与互联网有关的活动和手机的使用一直在蓬勃发展。关于电信,根据(AnSD),塞内加尔对技术和金融资源进行了大量投资,因为它为经济增长做出了 4.72%的贡献,并代表了国家计划中最重要的计划之一,即PSE(塞内加尔紧急计划)。但是,世界经济的过度自由化导致了全球化,全球化导致了所有市场,特别是电信部门的无情竞争。塞内加尔出现的问题是,从事该领域业务的公司难以成立,并且其与营销活动相关的策略无法适应客户的需求。因此,就市场份额和销售而言,这些公司中的大多数都遇到了困难,使他们无法达到理想的发展水平。实际上,尽管政府正在投资数十亿美元来发展该行业,但由于缺乏洞察力以及对客户以及竞争对手的反应迟钝,本地公司正在损失巨额资金。因此,除了缺乏财务手段外,主要问题是不采用获取市场份额和增加盈利能力的策略。开展的营销活动不够积极,不符合使用服务的人的要求,这可以解释几家公司退出该行业以及留下来的困难。在这方面,研究的目的是确定产品和促销相关活动对塞内加尔电信公司市场份额的影响。进行这项研究所需的数据是通过对电信服务消费者和该部门运营的管理人员进行问卷调查收集的。使用SPSS系统进行数据收集和分析,以确定我们分析中数据的可靠性和有效性。研究结果表明,多元化,可持续发展政策,赞助,促销,社交媒体广告以及主要的连接性对市场份额的影响为5%。我们还发现,直接营销被消费者认为是一种侵入性的方法,而利基方法不允许中小型公司获得大量的市场份额。

关键词：市场份额电信部门营销活动产品促销

检查清单和错误报告系统在提高患者安全和减少医疗差错方面的有效性:叙述性回顾

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International Journal of nursing Sciences 2024年第3期11卷 387-398页

作者： Emmanuel Aoudi Chance dia Florence Innocent Sardi Abdoul VID Specialized University BergenNorway Universite de Bertoua Cameroon Univerity of ngaoundere Cameroon

目的探讨检查清单和错误报告系统对医院患者安全和医疗错误的影响。方法系统检索2013-2023年的学术数据库,对符合纳入标准的同行评议研究进行严谨的方法学评估。该综述强调了支持核对表在减少用药错误、手术并发症和其他不良事件方面的... 详细信息

目的探讨检查清单和错误报告系统对医院患者安全和医疗错误的影响。方法系统检索2013-2023年的学术数据库,对符合纳入标准的同行评议研究进行严谨的方法学评估。该综述强调了支持核对表在减少用药错误、手术并发症和其他不良事件方面的有效性证据。错误报告系统提高了透明度,鼓励专业人员报告事件并识别系统漏洞。结果检查表和错误报告系统相互关联,在检查表的实施中强调跨专业合作。文章中使用的不同方法和潜在的发表偏倚可能产生局限性;此外,语言限制可能会排除有价值的非英语研究。虽然积极的影响是显而易见的,但成功取决于组织文化和资源。结论通过查阅相关文献,强调干预措施的重要性,并呼吁进一步研究检查清单和错误报告系统在不同医疗保健和文化背景下的有效性,有助于提高患者安全知识。了解这些动态变化对于医疗保健提供者优化患者安全至关重要。

关键词：患者安全医疗错误检查表错误报告系统健康状况

Mother-to-Child HIV Transmission Factors in Exposed Children at University Hospital Center of Treichville (Abidjan, Cote d’Ivoire)

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Open Journal of Obstetrics and Gynecology 2017年第12期7卷 1198-1208页

作者： Edouard n’Guessan Jean Marc Lamine dia Mouhideen Oyelade Ignace Yao Privat Guié Simplice Anongba Department of Obstetrics and Gynecology University Hospital of Treichville Abidjan Cote d’Ivoire

Background: The elimination of HIV transmission from mother to child is currently possible. Cote d’Ivoire, which has a 4.6% HIV prevalence among women, is one of 22 pilot countries for the elimination of mother-to-child transmission of HIV. Since 2015, Cote d’Ivoire has adopted new strategies according to the WHO B+ guidelines. Objective: To identify factors associated with mother-to-child HIV transmission in children born of seropositive mothers managed at Treichville university hospital. Material and methods: A case-control study was conducted in the obstetrics department at Treichville university hospital, between January 2013 and December 2015. It involved children born to mothers infected with HIV, whose first PCR (Polymerase Chain Reaction) result was available during this period. A standardized questionnaire on data related to exposed children and their mother was used. Factors associated with mother-to-child HIV transmission were investigated using logistic regression. Results: A total of 214 HIV-exposed children were included in the study with a sex ratio of 0.9. The majority of the children were born by vaginal route (52.8%) and received post-exposure prophylaxis (88.3%) and replacement feed (51.9%). Their mothers received antiretroviral therapy during pregnancy in 45.3% of the cases. The first PCR was performed at the sixth week of life in 52.3% of cases. The prevalence of HIV infection in exposed children was 7.5% (95% CI = 4.5% - 11.8%). In multivariate analysis, the absence of antiretroviral prophylaxis in children [aOR = 4.3, 95% (1.2 to 15.6), p = 0.03], the mixed feed [aOR = 3.8, 95% (1.1 - 13.1), p ntiretroviral regimen during pregnancy [aOR = 8.0, 95% CI (1.9 - 32.4), p nsmission. Conclusion: The mother-to-child HIV transmission rate remains high in our practice. Strategies to reduce situations that do not comply with current recommendations should be considered to pr

关键词： HIV-Exposed Children Mother-to-Child Transmission DBS/PCR

Study of the Factors Associated with Home Delivery in a Situation of Free Care in Senegal

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Open Journal of Epidemiology 2017年第4期7卷 326-336页

作者： Adama Faye Anta Tal-dia Daouda Faye Instute of Health and Development Cheikh Anta Diop University Dakar Sénégal Dental Public Health Service Cheikh Anta Diop University Dakar Sénégal

Introduction: Home delivery is still a health problem in Kolda (Senegal). The aim of this work is to study the factors associated with the place of delivery in a situation of free care delivery. Method: A descriptive and analytical cross-sectional study was carried out. Sampling was in two-stage clusters. The study focused on women who gave birth in the last 12months. The data were collected during an individual interview at home. The collection focused on knowledge, attitudes and practices about delivery. Logistic regression was used to explore the determinants of childbirth at the level of health facility. Results: The average age was 25.4 ± 6.5 years. Among the interviewed women, education was reported in 35% of the women and 55% of women estimate that the closest health facility is within 5 km to their home. The time to get to the nearest health facility is less than 15 minutes for 39% of the interviewed women. The prevalence of home delivery was 43.5%. Home delivery was related to the remoteness of the health facility (2.43 [1.75 - 3.37]) but also to incomplete antenatal care (2.52 [1.59 - 4.00]). Support groups highlighted difficulties of access to health facilities because of remoteness. Interviews revealed a lack of involvement of husbands in seeking care for women. Cultural barriers are still there. Conclusions: Despite the gratuity of delivery, the remoteness of health structures and socio-cultural factors are still barriers to access to care for pregnant women. These aspects must be taken into account in health policies. Multi-lateral interventions should be implemented to provide solutions for this health problem.

关键词： Home Delivery Free Care Health Facility Senegal

Imaging evaluation of the liver in oncology patients:A comparison of techniques

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World Journal of Hepatology 2021年第12期13卷 1936-1955页

作者： Patrícia S Freitas Catarina Janicas JoséVeiga António P Matos Vasco Herédia Miguel Ramalho Department of Radiology Centro Hospitalar Universitário de Lisboa CentralLisbon 1150-199Portugal Department of Radiology Centro Hospitalar de Lisboa OcidentalLisbon 1449-005Portugal Department of Radiology Hospital Garcia de OrtaEPEAlmada 2805-267Portugal Department of Radiology Hospital CUF TejoLisbon 1350-352Portugal Department of Radiology Hospital Espírito Santo deÉvora-EPEÉvora 7000-811Portugal Department of Radiology Hospital da LuzLisbon 1500-650Portugal

The liver is commonly affected by metastatic ***,it is essential to detect and characterize liver metastases,assuming that patient management and prognosis rely on *** imaging techniques that allow non-invasive assessment of liver metastases include ultrasonography,computed tomography(CT),magnetic resonance imaging(MRI),positron emission tomography(PET)/CT,and PET/*** this paper,we review the imaging findings of liver metastases,focusing on each imaging modality’s advantages and potential *** also assess the importance of different imaging modalities for the management,follow-up,and therapy response of liver *** date,both CT and MRI are the most appropriate imaging methods for initial lesion detection,follow-up,and assessment of treatment *** MRI is frequently used as a problem-solving technique for liver lesions and has evolved substantially over the past decade,including hardware and software developments and specific intravenous contrast *** studies have shown that MRI performs better in small-sized metastases and moderate to severe liver steatosis *** state-of-the-art MRI shows a greater sensitivity for detecting and characterizing liver metastases,CT remains the chosen *** also present the controversial subject of the"economic implication"to use CT over MRI.

关键词： Liver metastases Magnetic resonance imaging Computed tomography Oncology Ultrasound Follow-up

Potential of Lunasin Orally-Administered in Comparison to Intraperitoneal Injection to Inhibit Colon Cancer Metastasis <i>in Vivo</i>

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Journal of Cancer Therapy 2013年第6期4卷 34-43页

作者： Vermont P. dia Elvira Gonzalez de Mejia Department of Food Science and Human nutrition University of Illinois at Urbana-Champaign Urbana USA

Lunasin is a bioactive peptide originally isolated from soybean and has demonstrated chemopreventive and anti-cancer properties against skin, colon and breast cancers. The objective of the study was to evaluate the capability of intraperitoneally and orally-administered soybean-derived peptide lunasin to inhibit KM12L4 human colon cancer cell metastasis in a mouse model. Intraperitoneal (i.p.) injection of lunasin (4 mg/kg bw/day) reduced the number of liver metastasis by 50% (P = 0.047) and the liver weight/body weight ratio by 23% (P = 0.039). Oral administration of lunasin reduced the number of liver metastasis by 56% (8 mg/kg bw/day, P = 0.293) and 94% (20 mg/kg bw/day, P = 0.247). Immunohistochemical staining of the liver-tissue section showed that lunasin at 20 mg/kg bw dose did not significantly reduce the expression of proliferating cell nuclear antigen, increased the expression of proapoptotic Bax by 2.7-fold but also increased the expression of the antiapoptotic Bcl-2 by 3.8-fold. Regarding epigenetic markers, H3K18 was not significantly affected by either oral dose while H4K8 was dose dependently increased by 2.3-fold (P = 0.001, 8 mg/kg bw) and 2.7-fold (P s of administration used leading to digestion of lunasin when given by oral gavage. In conclusion, lunasin reduced colon cancer metastasis in vivo;however, more studies are needed to determine the oral dose of lunasin and prevent colon cancer metastasis.

关键词： Lunasin Colon Cancer Metastasis Apoptosis Histones