检索结果-南通市图书馆

Trained through generations

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Cellular & Molecular Immunology 2022年第6期19卷 653-654页

作者： Neha d.patil Jonathan d.Turner Mahesh S.desai Jacques Zimmer department of Infection and Immunity Luxembourg Institute of HealthEsch-sur-AlzetteLuxembourg Odense Research Center for Anaphylaxis Department of Dermatology and Allergy CenterOdense University HospitalUniversity of Southern DenmarkOdenseDenmark

The first scientists to coin the term“trained immunity”were Mihai ***,Jessica Quintin,and Jos *** der Meer in a‘Perspective’article in 2011[2].With the publication of vast amounts of experimental data and follow-up reviews,the concept that the innate immune system can develop a memory function in parallel to the well-recognized adaptive memory,mediated by B and T lymphocytes,is largely accepted.

关键词： Jess immunity generation

Organic bases as additives for steam-assisted gravity drainage

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Petroleum Science 2019年第6期16卷 1332-1343页

作者： Sean d.Brame Litan Li Biplab Mukherjee Pramod d.patil Stephanie Potisek Quoc P.Nguyen Petroleum and Geosystems Engineering department The University of Texas at Austin200 E.Dean KeetonAustinTX 78712USA The dow Chemical Company 230 Abner Jackson PkwyECB 2A183Lake JacksonTX 77566USA

Steam-assisted gravity drainage(SAGd)is a mature technology for bitumen recovery from oil ***,it is an energy-intensive process that requires large amounts of steam to heat and mobilize *** purpose of this work is to develop ways to enhance SAGd performance through the use of organic base *** research is approached from three focus areas that supplement and guide each other:characterization tests,sand-pack floods,and computational simulation.A number of key mechanisms for enhancing oil recovery were identified,high-temperature additive characterization tests were developed,and promising alkalis were tested in porous *** was employed to history-match sandpack flood production data,in order to demonstrate the effect of an additive on the oil–water relative *** on these results,it was concluded that oxygenated organic bases had the most potential for improving bitumen recovery through reducing the oil–water interfacial tension(IFT)by increasing the pH of the *** organic bases favorably modify the interfacial energies between the immiscible oil–water phases and enable them to flow easily through the porous media during ***-pack flood tests have successfully demonstrated a 10%–15%improvement in bitumen recovery,over baseline,in the presence of IFT-reducing *** results further showed that an IFT reduction had a positive impact on SAGd *** work demonstrates the potential of organic bases to improve not only SAGd,but other steam injection ***,a number of experimental methods were developed,tried,and tested during the course of this work.

关键词： Heavy oil Steam flood Low interfacial tension Wettability Enhanced oil recovery Organic bases

Potential of herbal constituents as new natural leads against helminthiasis: A neglected tropical disease

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Asian Pacific Journal of Tropical Medicine 2019年第7期12卷 291-299页

作者： Kiran d.patil Shashikant B.Bagade Sanjay R.Sharma Ketan V.Hatware NMIMS School of Pharmacy and Technology Management

The WHO reports that billions of people and animals in tropical and subtropical regions are affected by helminthiasis as neglected tropical disease. It is predominant in underdeveloped areas;nevertheless, the increase in the number of travelers and migrants has made this infection more common. The current mass drug treatment produces severe side effects and many strains of helminths are resistant to them. None of the chemotherapeutic drugs meets the ideal requirements of anthelmintics, such as broad spectrum of activity, single dose cure, free from side effect and cost-effectiveness. Today, many researchers are screening the traditional herbal system in search of the anthelmintic herbal constituents which overcome all the problems of synthetic drugs. Several researchers proclaim anthelmintic activity of herbal medicines by using different experimental models. The present review demonstrates natural product drug discovery, outlining potential of herbal constituents from natural sources as natural leads against helminthiasis.

关键词： Neglected tropical diseases Herbal constituents Helminthiasis Herbal anthelmintics

Pharmaceutical and nutraceutical potential of natural bioactive pigment:astaxanthin

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Natural Products and Bioprospecting 2022年第1期12卷 367-392页

作者： Apurva d.patil Pramod J.Kasabe Padma B.dandge department of Biochemistry Shivaji UniversityKolhapur 416004Maha-rashtraIndia School of Nanoscience and Biotechnology Shivaji UniversityKolhapurMaharashtraIndia

Astaxanthin(3,3′-dihydroxy-β,β-carotene-4,4′-dione)is an orange-red,lipophilic keto-carotenoid *** is majorly found in marine ecosystems particularly in aquatic animals such as salmon,shrimp,trout,krill,crayfish,and so *** is also synthesized in microalgae Heamatococcus pluvialis,Chlorococcum,Chlorella zofingiensis,red yeast Phaffia rhodozyma and bacterium Paracoccus *** aquatic and terrestrial creatures regarded as a primary and secondary sources of the astaxanthin producing and accumulating it through their metabolic ***-anthin is the powerful antioxidant,nutritional supplement as well as promising therapeutic compound,observed to have activities against different ravaging diseases and *** have reported remarkable bioactivities of astaxanthin against major non-communicable chronic diseases such as cardiovascular diseases,cancer,diabetes,neurodegenerative,and immune *** current review discusses some structural aspects of *** fur-ther elaborates its multiple potencies such as antioxidant,anti-inflammatory,anti-proliferative,anti-cancer,anti-obese,anti-diabetic,anti-ageing,anti-TB,anti-viral,anti-COVId 19,neuro-protective,nephro-protective,and fertility-enhanc-ing *** potencies make it a more precious entity in the preventions as well as treatments of prevalent systematic diseases and/or ***,the review is acknowledging and documenting its powerful bioactivities in relation with the pharmaceutical as well as nutraceutical applicability.

关键词： Astaxanthin Nutritional supplement Therapeutic compound Chronic diseases Fertility enhancer

Nanoemulsion containing a synergistic combination of curcumin and quercetin for nose-to-brain delivery:In vitro and in vivo studies

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Asian Pacific Journal of Tropical Biomedicine 2021年第11期11卷 510-518页

作者： Hitendra S Mahajan Nayana d.patil r.3.patel institute of pharmaceutical education and research shirpurdist-dhule(m.s)india

Objective:To characterize a nanoemulsion containing a synergistic combination of curcumin(CUR)and quercetin(QUE)for brain targeting through the ***:The synergistic activity of the combination of two phytoconstituents,curcumin and quercetin(CUR-QUE)was determined at a 2:1 *** containing the synergistic combination were prepared using high-pressure homogenization *** formulation was characterized for globule size,drug content,thermodynamic stability,zeta potential measurement,and drug *** studies were performed using isolated nasal mucosa of ***,in vivo studies using allograft model were ***:CUR-QUE in a 2:1 ratio combination showed the lowest combination index values 0.99(combination indexd the growth of human glioblastoma U373 MG *** significant drug targeting efficiency percentage(178.25±2.86 for CUR and 170.54±6.11 for QUE)and nose to brain drug direct transport percentage(44.05±0.93 for CUR and 38.25±0.83 for QUE)of optimized nanoemulsion(F9)indicated effective central nervous system targeting via the intranasal *** vivo anticancer study using allograft model of nude mice demonstrated potential anticancer activity of the synergistic combination of CUR-QUE as compared to ***:This study demonstrates that synergistic combination of CUR-QUE was optimal for treatment of human ***,significant site-specific delivery to the brain was achieved by administering nanoemulsion through the *** study also reveals that intranasal delivery of nanoemulsion containing synergistic combination of CUR and QUE could be a promising strategy for brain tumor treatment.

关键词： Curcumin Quercetin Nanoemulsion Brain tumor Synergism

Cysticercosis of the neck:a case report

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Asian Pacific Journal of Tropical Medicine 2010年第10期3卷 833-834页

作者： Chandrakant patil Rashmi Kharat(patil) Prasad deshmukh Blenda d'Souza department of E.N.T J.N.M.CSawangiWardhaMaharashtra

The neck is a rare site for *** few cases of cysticercosis presenting in the neck have been *** report one such case creating diagnostic dilemma.

关键词： Cysticercosis Neck

Non-Spherical Gravitational Collapse of Strange Quark Matter

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Physics Letters 2008年第5期25卷 1568-1570页

作者： Zade S S patil K d Mulkalwar P N department of Mathematics J. B. College of Science Wardha India department of Mathematics B. D. College of Engineering Sewagram Wardha India department of Computer Science Amolakchand Mahavidyalaya Yavatmal India

We study the non-spherical gravitational collapse of the strange quark null fluid. The interesting feature which emerges is that the non-spherical collapse of charged strange quark matter leads to a naked singularity whereas the gravitational collapse of neutral quark matter proceeds to form a black hole. We extend the earlier work of Harko and Cheng [Phys. Lett. A 266 （2000） 249] to the non-spherical case.

关键词： NAKEd SINGULARITIES COSMIC CENSORSHIP SPACETIMES

Tuberculous retropharyngeal abscess without cervical spine TB

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Asian Pacific Journal of Tropical Medicine 2011年第3期4卷 251-252页

作者： Chandrakant patil Rashmi Kharat(patil) Prasad deshmukh Sameer Singhal Blenda d'Souza department of E.N.T J.N.M.C SawangiWardhaMaharashtraIndia department of Pulmonary Medicine Acharya Vinoba Bhave Rural HospitalSawangi(M)WardhaMaharashtra-442004India

Tuberculous retropharyngeal abscess is a rare *** is present in adults usually due to involvement of cervical spine by *** space usually gets involved in children due to pyogenic organisms or secondary to *** is a case of tuberculous retropharyngeal abscess in an adult female,with pulmonary *** patient was not having tuberculous involvement of cervical spine and was managed surgically by aspirating the retropharyngeal abscess transorally and AKT Category I.

关键词： Tuberculous Retropharyngeal abscess Aspiration

Lattice thermal conduction in cadmium arsenide

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Physics B 2022年第11期31卷 424-430页

作者： R F Chinnappagoudra M d Kamatagi N R patil N S Sankeshwar department of Physics S.S.Government First Grade CollegeNargund-582207KarnatakaIndia Research Resource Centre Visvesvaraya Technological UniversityBelagavi-590018KarnatakIndia department of Physics B V B College of Engineering and TechnologyHubliKarnataka 80031India department of Physics&Electronics CHRIST(Deemed to be University)Bangalore-560029KarnatakaIndia

Lattice thermal conductivity(LTC)of cadmium arsenide(Cd_(3)As_(2))is studied over a wide temperature range(1–400 K)by employing the Callaway *** acoustic phonons are considered to be the major carriers of heat and to be scattered by the sample boundaries,disorder,impurities,and other phonons via both Umklapp and normal phonon *** calculations of LTC of Cd_(3)As_(2)bring out the relative importance of the scattering *** systematic analysis of recent experimental data on thermal conductivity(TC)of Cd_(3)As_(2)samples of different groups,presented in terms of LTC,κL,using a nonlinear regression method,reveals good fits to the TC data of the samples considered for Td suggests a value of 0.2 for the Gruneisen *** is,however,found that for T>100 K the inclusion of the electronic component of TC,κe,incorporating contributions from relevant electron scattering mechanisms,is needed to obtain good agreement with the TC data over the wide temperature *** detailed investigations of TC of Cd_(3)As_(2)are required to better understand its suitability in thermoelectric and thermal management devices.

关键词： dirac semimetals Cd_(3)As_(2) thermal conductivity phonon scattering