检索结果-南通市图书馆

Rice-wheat comparative genomics:Gains and gaps

The Crop Journal 2024年第3期12卷 656-669页

作者： Akila Wijerathna-Yapa Ruchi Bishnoi Buddhini Ranawaka Manu Maya Magar Hafeez ur rehman Swati G.Bharad Michal T.Lorenc Vinita Ramtekey Sasha Gohar Charu Lata Md.Harun-Or-Rashid Maryam Razzaq muhammad Sajjad Bhoja *** School of Agriculture and Food Sustainability The University of QueenslandSt LuciaQLD 4072Australia ARC Centre of Excellence for Plant Success in Nature and Agriculture The University of QueenslandSt LuciaQLD 4072Australia Department of Genetics and Plant Breeding College of AgricultureUmmedganj-KotaAgriculture UniversityKotaRajasthan 324001India Centre for Agriculture and the Bioeconomy Queensland University of Technology(QUT)2 George StreetBrisbaneQLD 4000Australia UWA School of Agriculture and Environment The University of Western Australia35 Stirling HighwayCrawleyWA 6009Australia Nepal Agriculture Research Council KhumaltarLalitpurNepal Department of Agronomy University of AgricultureFaisalabad 38040Pakistan Department of Agricultural Botany Dr Panjabrao Deshmukh Krishi VidyapeethAkola 444104MaharashtraIndia ICAR-Indian Institute of Seed Science MauUttar Pradesh 275103India School of Natural Sciences Macquarie UniversityMacquarie ParkNSW 2109Australia ICAR-Indian Institute of Wheat and Barley Research Flowrdale 54642ShimlaIndia International Maize and Wheat Improvement Center(CIMMYT)Bangladesh Office Gulshan-2Dhaka 1212Bangladesh Center for Seed Science University of AgricultureFaisalabad 38000Pakistan Department of Biosciences COMSATS University IslamabadPark RoadTarlai KalanIslamabad 45550Pakistan CGIAR’s Excellence in Breeding(EiB)Platform/Accelerated Breeding Initiative International Maize and Wheat Improvement Center(CIMMYT)El Batán 56237Mexico

Rice and wheat provide nearly 40%of human calorie and protein *** share a common ancestor and belong to the Poaceae(grass)*** their genetic homology is crucial for developing new cultivars with enhanced *** wheat genes and gene families have been characterized based on their rice ***–wheat orthology can identify genetic regions that regulate similar traits in both ***–wheat comparative genomics can identify candidate wheat genes in a genomic region identified by association or QTL mapping,deduce their putative functions and biochemical pathways,and develop molecular markers for marker-assisted breeding.A knowledge of gene homology facilitates the transfer between crops of genes or genomic regions associated with desirable traits by genetic engineering,gene editing,or wide crossing.

关键词： Comparative genomics Orthologs Genes Synteny Genetic engineering Molecular breeding

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Assessing forest cover changes and fragmentation in the Himalayan temperate region: implications for forest conservation and management

引用

Journal of Forestry Research 2024年第4期35卷 128-141页

作者： Kaleem Mehmood Shoaib Ahmad Anees Akhtar rehman Aqil Tariq Qijing Liu Sultan muhammad Fazli Rabbi Shao’an Pan Wesam Atef Hatamleh College of Forestry Beijing Forestry UniversityBeijing 100083People’s Republic of China Institute of Agriculture Sciences and Forestry University of SwatSwatPakistan Department of Forestry The University of AgricultureDera Ismail Khan 29050Pakistan Key Laboratory for Silviculture and Conservation of Ministry of Education Beijing Forestry UniversityBeijing 100083People’s Republic of China Beijing Key Laboratory of Precision Forestry Forestry CollegeBeijing Forestry UniversityBeijing 100083People’s Republic of China School of Environmental Studies China University of GeosciencesWuhan 430074People’s Republic of China Department of Wildlife Fisheries and AquacultureCollege of Forest ResourcesMississippi State UniversityStarkvilleMS 39762‑9690USA School of Management Tianjin University of CommerceTianjin 300134People’s Republic of China Department of Computer Science College of Computer and Information SciencesKing Saud UniversityP.O.Box 5117811543 RiyadhSaudi Arabia

This study comprehensively assessed long-term vegetation changes and forest fragmentation dynamics in the Himalayan temperate region of Pakistan from 1989 to *** satellite images,including Landsat-5 TM and Landsat-8 Operational Land Imager(OLI),were chosen for subsequent assessments in October 1989,2001,2011 and *** classified maps of 1989,2001,2011 and 2019 were created using the maximum likelihood ***-classification comparison showed an overall accuracy of 82.5%and a Kappa coefficient of 0.79 for the 2019 *** revealed a drastic decrease in closed-canopy and open-canopy forests by 117.4 and 271.6 km^(2),respectively,and an increase in agriculture/farm cultivation by 1512.8 km^(2).The two-way ANOVA test showed statistically significant differences in the area of various cover *** fragmentation was evaluated using the Landscape Fragmentation Tool(LFT v2.0)between 1989 and *** large forest core(>2.00 km^(2))decreased from 149.4 to 296.7 km^(2),and a similar pattern was observed in medium forest core(1.00-2.00 km^(2))*** the contrary,the small core(urgent need for efficient management,conservation,and restoration *** on these findings,sustainable land-use policies may be put into place that support local livelihoods,protect ecosystem services,and conserve biodiversity.

关键词： Natural catastrophes Landsat Change detection Forest fragmentation Landscape fragmentation tool(LFT) Afforestation Reforestation

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Improving Thyroid Disorder Diagnosis via Ensemble Stacking and Bidirectional Feature Selection

引用

Computers, Materials & Continua 2024年第3期78卷 4225-4241页

作者： muhammad Armghan Latif Zohaib Mushtaq Saad Arif Sara rehman muhammad Farrukh Qureshi Nagwan Abdel Samee Maali Alabdulhafith Yeong Hyeon Gu Mohammed A.Al-masni Department of Computer and Information System Cleveland State UniversityOhio44115USA Department of Electrical Electronics and Computer SystemsCollege of Engineering and TechnologyUniversity of SargodhaSargodha40100Pakistan Department of Mechanical Engineering College of EngineeringKing Faisal UniversityAl-Ahsa31982Saudi Arabia Department of Biomedical Engineering Riphah International UniversityIslamabad44000Pakistan Department of Electrical Engineering Riphah International UniversityIslamabad44000Pakistan Department of Information Technology College of Computer and Information SciencesPrincess Nourah bint Abdulrahman UniversityP.O.Box 84428Riyadh11671Saudi Arabia Department of Artificial Intelligence College of Software and Convergence TechnologySejong UniversitySeoul05006Korea

Thyroid disorders represent a significant global health challenge with hypothyroidism and hyperthyroidism as two common conditions arising from dysfunction in the thyroid *** and timely diagnosis of these disorders is crucial for effective treatment and patient *** research introduces a comprehensive approach to improve the accuracy of thyroid disorder diagnosis through the integration of ensemble stacking and advanced feature selection *** forward feature selection,sequential backward feature elimination,and bidirectional feature elimination are investigated in this *** ensemble learning,random forest,adaptive boosting,and bagging classifiers are *** effectiveness of these techniques is evaluated using two different datasets obtained from the University of California Irvine-Machine Learning Repository,both of which undergo preprocessing steps,including outlier removal,addressing missing data,data cleansing,and feature *** experimentation demonstrates the remarkable success of proposed ensemble stacking and bidirectional feature elimination achieving 100%and 99.86%accuracy in identifying hyperthyroidism and hypothyroidism,*** enhancing detection accuracy,the ensemble stacking model also demonstrated a streamlined computational complexity which is pivotal for practical medical *** significantly outperformed existing studies with similar objectives underscoring the viability and effectiveness of the proposed *** research offers an innovative perspective and sets the platform for improved thyroid disorder diagnosis with broader implications for healthcare and patient well-being.

关键词： Ensemble learning random forests boosting dimensionality reduction machine learning smart healthcare computer aided diagnosis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Impact of COVID-19 on liver transplant recipients: A nationwide cohort study evaluating hospitalization, transplant rejection, and inpatient mortality

引用

World Journal of Transplantation 2024年第2期14卷 62-75页

作者： Faisal Inayat Pratik Patel Hassam Ali Arslan Afzal Hamza Tahir Ahtshamullah Chaudhry Rizwan Ishtiaq Attiq ur rehman Kishan Darji muhammad Sohaib Afzal Gul Nawaz Alexa Giammarino Sanjaya K Satapathy Department of Internal Medicine Allama Iqbal Medical CollegeLahorePunjab 54550Pakistan Division of Gastroenterology Mather Hospital and Zucker School of Medicine at Hofstra UniversityPort JeffersonNY 11777United States Division of Gastroenterology and Hepatology East Carolina University Brody School of MedicineGreenvilleNC 27834United States Department of Internal Medicine Jefferson Einstein HospitalPhiladelphiaPA 19141United States Department of Internal Medicine St.Dominic's HospitalJacksonMS 39216United States Department of Internal Medicine Saint Francis Hospital and Medical CenterHartfordCT 06105United States Division of Hepatology Geisinger Wyoming Valley Medical CenterWilkes-BarrePA 18711United States Department of Internal Medicine Campbell University and Cape Fear Valley Medical CenterFayettevilleNC 28301United States Department of Internal Medicine North Shore University Hospital and Zucker School of Medicine at Hofstra UniversityManhassetNY 11030United States Division of Hepatology North Shore University Hospital and Zucker School of Medicine at Hofstra UniversityManhassetNY 11030United States

BACKGROUND The coronavirus disease 2019(COVID-19)pandemic has posed a major public health concern *** with comorbid conditions are at risk of adverse outcomes following *** organ transplant recipients with concurrent immunosuppression and comorbidities are more susceptible to a severe COVID-19 *** could lead to higher rates of inpatient complications and mortality in this patient ***,studies on COVID-19 outcomes in liver transplant(LT)recipients have yielded inconsistent *** To evaluate the impact of the COVID-19 pandemic on hospital-related outcomes among LT recipients in the United *** We conducted a retrospective cohort study using the 2019–2020 National Inpatient Sample *** with primary LT hospitalizations and a secondary COVID-19 diagnosis were identified using the International Classi-fication of Diseases,Tenth Revision coding *** primary outcomes included trends in LT hospitalizations before and during the COVID-19 *** outcomes included comparative trends in inpatient mortality and transplant rejection in LT *** A total of 15720 hospitalized LT recipients were *** 0.8% of patients had a secondary diagnosis of COVID-19 *** both cohorts,the median admission age was 57 *** linear trends for LT hospitalizations did not differ significantly before and during the pandemic(P=0.84).The frequency of in-hospital mortality for LT recipients increased from 1.7% to 4.4% between January 2019 and December *** to the pre-pandemic period,a higher association was noted between LT recipients and in-hospital mortality during the pandemic,with an odds ratio(OR)of 1.69[95% confidence interval(CI):1.55-1.84),Puring the COVID-19 pandemic had a higher associ

关键词： Liver transplant recipients Solid organ transplantation COVID-19 Hospitalization Transplant rejection Mortality

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Bond-Slip Behavior of Steel Bar and Recycled Steel Fibre-Reinforced Concrete

引用

Journal of Renewable Materials 2024年第1期12卷 167-186页

作者： Ismail Shah Jing Li Nauman Khan Hamad R.Almujibah muhammad Mudassar rehman Ali Raza Yun Peng School of Architecture and Civil Engineering Yunnan Agricultural UniversityKunming650000China Institute of Mountain Hazards and Environment Chinese Academy of SciencesChengdu610041China Yunnan International Joint R&D Center of Smart Agriculture and Water Security Yunnan Agricultural UniversityKunming650201China School of Water Conservancy Yunnan Agricultural UniversityKunming650201China School of Civil Engineering Guizhou UniversityGuiyang550025China Department of Civil Engineering College of EngineeringTaif UniversityP.O.Box 11099Taif City21974Saudi Arabia School of Civil Engineering Zhengzhou UniversityZhengzhou450001China

Recycled steel fiber reinforced concrete is an innovative construction material that offers exceptional mechanical properties and *** is considered a sustainable material due to its low carbon footprint and environmental friendly *** study examines the key influencing factors that affect the behavior of this material,such as the steel fiber volume ratio,recycled aggregate replacement rate,concrete strength grade,anchorage length,and stirrup *** study investigates the bond failure morphology,bond-slip,and bond strength constitutive relationship of steel fiber recycled *** results show that the addition of steel fibers at 0.5%,1.0%,and 1.5%volume ratios can improve the ultimate bond strength of pull-out specimens by 9.05%,6.94%,and 5.52%,*** replacement rate of recycled aggregate has minimal effect on the typical bond strength of pull-out ***,the ultimate bond strengths of pull-out specimens with concrete strength grades C45 and C60 have improved compared to those with C30 *** specimens with longer anchorage lengths exhibit lower ultimate bond strength,with a reduction of 33.19%and 46.37%for anchorage lengths of 5D and 7D,respectively,compared to those without *** restraint of 1φ8 and 2φ8 improves the ultimate bond strength by 5.29%and 6.90%,*** fibers have a significant effect on the behavior of concrete after it cracks,especially during the stable expansion stage,crack instability expansion stage,and failure stage.

关键词： Recycled coarse aggregates(RCA) steel fiber bonding performance bond-slip environmental challenges

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Roles of Mutant TP53 Gene in Cancer Development and Progression

引用

Proceedings of Anticancer Research 2024年第5期8卷 165-181页

作者： muhammad Abubakar Baqaur rehman Department of Biosciences COMSATS University IslamabadIslamabad Capital Territory 45550Pakistan

TP53 is a tumor suppressor gene that is mutated in most cancer types and has been extensively studied in cancer research.p53 plays a critical role in regulating the expression of target genes and is involved in key processes such as apoptosis,cell cycle regulation,and genomic stability,earning it the title“guardian of the genome.”Numerous studies have demonstrated p53’s influence on and regulation of autophagy,ferroptosis,the tumor microenvironment,and cell metabolism,all of which contribute to tumor *** in p53,specifically mutant p53(mutp53),not only impair its tumor-suppressing functions but also enhance oncogenic *** data indicate that mutp53 is strongly associated with poor prognosis and advanced cancers,making it an ideal target for the development of novel cancer *** review summarizes the post-translational modifications of p53,the mechanisms of mutp53 accumulation,and its gain-of-function,based on previous ***,this review discusses its impact on metabolic homeostasis,ferroptosis,genomic instability,the tumor microenvironment,and cancer stem cells,and highlights recent advancements in mutp53 research.

关键词： p53 Cancer Mutant p53(mutp53) Progression Treatment

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Association between acute peripancreatic fluid collections and early readmission in acute pancreatitis:A propensity-matched analysis

引用

World Journal of Experimental Medicine 2024年第2期14卷 75-88页

作者： Hassam Ali Faisal Inayat Waqas Rasheed Arslan Afzal Ahtshamullah Chaudhry Pratik Patel Attiq ur rehman muhammad Sajeel Anwar Gul Nawaz muhammad Sohaib Afzal Amir H Sohail Subanandhini Subramanium Dushyant Singh Dahiya Deepa Budh Babu P Mohan Douglas G Adler Department of Gastroenterology and Hepatology East Carolina University Brody School of MedicineGreenvilleNC 27834United States Department of Internal Medicine Allama Iqbal Medical CollegeLahorePunjab 54550Pakistan Department of Internal Medicine Texas Tech University Health Sciences CenterLubbockTX 79430United States Department of Internal Medicine St.Dominic’s HospitalJacksonMS 39216United States Department of Gastroenterology Mather Hospital and Hofstra University Zucker School of MedicinePort JeffersonNY 11777United States Department of Hepatology Geisinger Wyoming Valley Medical CenterWilkes-BarrePA 18711United States Department of Internal Medicine UHS Wilson Medical CenterJohnson CityNY 13790United States Department of Internal Medicine Louisiana State University HealthShreveportLA 71103United States Department of Surgery University of New Mexico School of MedicineAlbuquerqueNM 87106United States Division of Gastroenterology Hepatologyand MotilityThe University of Kansas School of MedicineKansas CityKS 64108United States Department of Internal Medicine St.Barnabas Hospital and Albert Einstein College of MedicineBronxNY 10457United States Department of Gastroenterology and Hepatology University of Utah School of MedicineSalt Lake CityUT 84132United States Center for Advanced Therapeutic Endoscopy Porter Adventist HospitalCentura HealthDenverCO 80210United States

BACKGROUND Patients with acute pancreatitis(AP)frequently experience hospital readmissions,posing a significant burden to healthcare *** peripancreatic fluid collection(APFC)may negatively impact the clinical course of *** could worsen symptoms and potentially lead to additional ***,clinical evidence regarding the specific association between APFC and early readmission in AP remains *** the link between APFC and readmission may help improve clinical care for AP patients and reduce healthcare *** To evaluate the association between APFC and 30-day readmission in patients with *** This retrospective cohort study is based on the Nationwide Readmission Database for *** with a primary diagnosis of AP were *** were categorized into those with and without APFC.A 1:1 propensity score matching for age,gender,and Elixhauser comorbidities was *** primary outcome was early readmission *** outcomes included the incidence of inpatient complications and healthcare *** analyses used Mann-Whitney U andχ2 tests,while Cox regression models assessed 30-day readmission risks and reported them as adjusted hazard ratios(aHR).Kaplan-Meier curves and log-rank tests verified readmission *** A total of 673059 patients with the principal diagnosis of AP were *** these,5.1%had APFC on initial *** propensity score matching,each cohort consisted of 33914 *** with APFC showed a higher incidence of inpatient complications,including septic shock(3.1%vs 1.3%,P<0.001),portal venous thrombosis(4.4%vs 0.8%,P<0.001),and mechanical ventilation(1.8%vs 0.9%,P<0.001).The length of stay(LOS)was longer for APFC patients[4(3-7)vs 3(2-5)days,P<0.001],as were hospital charges($29451 vs$24418,P<0.001).For 30-day readmissions,APFC patients had a higher rate(15.7%vs 6.5%,P<0.001)and a longer median readmission LOS(4 vs 3 days,P<0.001).The APF

关键词： Acute pancreatitis Acute peripancreatic fluid collections Readmission predictors Inpatient complications Healthcare utilization and costs

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

A Review of Rechargeable Zinc-Air Batteries:Recent Progress and Future Perspectives

引用

Nano-Micro Letters 2024年第7期16卷 358-401页

作者： Ghazanfar Nazir Adeela rehman Jong-Hoon Lee Choong-Hee Kim Jagadis Gautam Kwang Heo Sajjad Hussain muhammad Ikram Abeer AAlObaid Seul-Yi Lee Soo-Jin Park Department of Nanotechnology and Advanced Materials Engineering Hybrid Materials Research Center(HMC)Sejong UniversitySeoul 05006Republic of Korea Department of Chemical and Biomolecular Engineering Yonsei University50 Yonsei-RoSeodaemun-GuSeoul 03722Republic of Korea Department of Chemistry Inha UniversityIncheon 22212Republic of Korea Solar Cell Applications Research Lab Department of PhysicsGovernment College University LahoreLahore 54000 PunjabPakistan Department of Chemistry College of ScienceKing Saud UniversityP.O.Box 2455Riyadh 11451Saudi Arabia

Zinc-air batteries(ZABs)are gaining attention as an ideal option for various applications requiring high-capacity batteries,such as portable electronics,electric vehicles,and renewable energy *** offer advantages such as low environmental impact,enhanced safety compared to Li-ion batteries,and cost-effectiveness due to the abundance of ***,early research faced challenges due to parasitic reactions at the zinc anode and slow oxygen redox *** advancements in restructuring the anode,utilizing alternative electrolytes,and developing bifunctional oxygen catalysts have significantly improved *** have achieved battery reversibility over thousands of cycles,introduced new electrolytes,and achieved energy efficiency records surpassing 70%.Despite these achievements,there are challenges related to lower power density,shorter lifespan,and air electrode corrosion leading to performance *** review paper discusses different battery configurations,and reaction mechanisms for electrically and mechanically rechargeable ZABs,and proposes remedies to enhance overall battery *** paper also explores recent advancements,applications,and the future prospects of electrically/mechanically rechargeable ZABs.

关键词： Zinc-air batteries Energy storage Affordability Reversibility

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Evaluating the Potential of Nitrofurantoin and Fosfomycin for *** UTIs: A Susceptibility Study

引用

Journal of Clinical and Nursing Research 2024年第6期8卷 351-358页

作者： Usama Ahmed muhammad Zubair Baqaur rehman Hafiz muhammad Sultan Department of Medicine School of Biomedical EngineeringShenzhen University Medical SchoolShenzhen 518060China Institute of Biological Sciences Khwaja Fareed University of Engineering and Information TechnologyRahim Yar KhanPakistan Department of Biosciences COMSATS University IslamabadPark RdIslamabad Capital Territory 45550Pakistan Crop Diseases Research Institute(CDRI) National Agricultural Research Centre NARCIslamabadPakistan

This study was designed to find the susceptibility of Nitrofurantoin and Fosfomycin among urinary isolates of *** hundred(400)urine samples were collected for susceptibility of nitrofurantoin and fosfomycin among urinary isolates of *** indoor and outdoor patients'urinary samples yielded growth of ***-stream urine specimens were inoculated on blood agar and CLED agar and incubated at 35±2°*** was observed,and Escherichia coli was identified by Gram staining,Catalase,Motility test and API 20E(Bio murex)as per standard *** susceptibility testing of isolates for nitrofurantoin and fosfomycin was carried out by the modified Kirby-Bauer disc diffusion method according to CLSI guidelines ATCC *** was used as a quality control strain.A total of 400 samples were tested susceptibility of nitrofurantoin and fosfomycin among urinary isolates of *** during this period.A total of 400 samples yielded the growth of ***,out of which 178(44.5%)were male and 222(55.5%)were female *** males,18(10%)were tolerant to nitrofurantoin,and 2(1.1%)were tolerant to *** females,9(4.09%)were susceptible to nitrofurantoin while 6(2.72%)were susceptible to *** age groups below 45 years old,6(4.76%)were tolerant to nitrofurantoin,and 2(1.58%)were sensitive to *** 46-66 years old,4(2.81%)were sensitive to nitrofurantoin,and 3(2.11%)were sensitive to *** 67-90 years old,17(12.87%)were sensitive to nitrofurantoin,and 4(3.03%)were tolerant to *** and nitrofurantoin showed good susceptibility in urinary isolates of *** and can be used empirically in our setup.

关键词： E.coli Fosfomycin Nitrofurantoin Susceptibility urinary isolates

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Analysis of Genetic Alterations in TP53 Gene in Breast Cancer - A Secondary Publication

引用

Proceedings of Anticancer Research 2024年第3期8卷 25-35页

作者： Baqaur rehman muhammad Abubakar muhammad Naeem Kiani Rooma Ayyoub Department of Biosciences COMSATS University IslamabadPark RdIslamabad Capital Territory 45550Pakistan Guangdong Key Laboratory of Biomedical Measurements and Ultrasound Imaging School of Biomedical EngineeringShenzhen University Medical SchoolShenzhen UniversityShenzhen 518060China

Tumor protein p53 (TP53) mediates DNA repair and cell proliferation in growing cells. The TP53 gene is a tumor suppressor that regulates the expression of target genes in response to multiple cellular stress factors. Key target genes are involved in crucial cellular events such as DNA repair, cell cycle regulation, apoptosis, metabolism, and senescence. TP53 genetic variants and the activity of the wild-type p53 protein (WT-p53) have been linked to a wide range of tumorigenesis. Various genetic and epigenetic alterations, including germline and somatic mutations, loss of heterozygosity, and DNA methylation, can alter TP53 activity, potentially resulting in cancer initiation and progression. This study was designed to screen three reported mutations in the DNA-binding domain of the p53 protein in breast cancer, to evaluate the relative susceptibility and risk associated with breast cancer in the local population. Genomic DNA was isolated from 30 breast tumor tissues along with controls. Tetra and Tri ARMS PCR were performed to detect mutations in the TP53 coding region. For SNPs c.637C>T and c.733C>T, all analyzed cases were homozygous for the wild-type allele ‘C,’ while for SNP c.745A>G, all cases were homozygous for the wild-type allele ‘A.’ These results indicate no relevance of these three SNPs to cancer progression in our study cohort. Additionally, the findings from whole exon sequencing will help to predict more precise outcomes and assess the importance of TP53 gene mutations in breast cancer patients.

关键词： Breast cancer p53 Gene expression Mutation SNPs

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：