Evaluating the Potential of Nitrofurantoin and Fosfomycin for *** UTIs: A Susceptibility Study

作     者：Usama Ahmed Muhammad Zubair Baqaur Rehman Hafiz Muhammad Sultan 

作者机构：Department of MedicineSchool of Biomedical EngineeringShenzhen University Medical SchoolShenzhen 518060China Institute of Biological SciencesKhwaja Fareed University of Engineering and Information TechnologyRahim Yar KhanPakistan Department of BiosciencesCOMSATS University IslamabadPark RdIslamabad Capital Territory 45550Pakistan Crop Diseases Research Institute(CDRI)National Agricultural Research Centre NARCIslamabadPakistan 

出 版 物：《Journal of Clinical and Nursing Research》 (临床护理研究（英文）)

年 卷 期：2024年第8卷第6期

页      面：351-358页

学科分类：1002[医学-临床医学] 100210[医学-外科学(含：普外、骨外、泌尿外、胸心外、神外、整形、烧伤、野战外)] 10[医学] 

主　　题：E.coli Fosfomycin Nitrofurantoin Susceptibility Urinary isolates 

摘      要：This study was designed to find the susceptibility of Nitrofurantoin and Fosfomycin among urinary isolates of *** hundred(400)urine samples were collected for susceptibility of nitrofurantoin and fosfomycin among urinary isolates of *** indoor and outdoor patients urinary samples yielded growth of ***-stream urine specimens were inoculated on blood agar and CLED agar and incubated at 35±2°*** was observed,and Escherichia coli was identified by Gram staining,Catalase,Motility test and API 20E(Bio murex)as per standard *** susceptibility testing of isolates for nitrofurantoin and fosfomycin was carried out by the modified Kirby-Bauer disc diffusion method according to CLSI guidelines ATCC *** was used as a quality control strain.A total of 400 samples were tested susceptibility of nitrofurantoin and fosfomycin among urinary isolates of *** during this period.A total of 400 samples yielded the growth of ***,out of which 178(44.5%)were male and 222(55.5%)were female *** males,18(10%)were tolerant to nitrofurantoin,and 2(1.1%)were tolerant to *** females,9(4.09%)were susceptible to nitrofurantoin while 6(2.72%)were susceptible to *** age groups below 45 years old,6(4.76%)were tolerant to nitrofurantoin,and 2(1.58%)were sensitive to *** 46-66 years old,4(2.81%)were sensitive to nitrofurantoin,and 3(2.11%)were sensitive to *** 67-90 years old,17(12.87%)were sensitive to nitrofurantoin,and 4(3.03%)were tolerant to *** and nitrofurantoin showed good susceptibility in urinary isolates of *** and can be used empirically in our setup.