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World Journal of Gastroenterology 2024年第36期30卷 4078-4082页

作者： Hania Haque Syeda Warisha Zehra mohammad shahzaib Saif Abbas Nazish Jaffar of Medicine Jinnah Sindh Medical UniversityKarachi 75510SindhPakistan Department of Pathology Jinnah Sindh Medical UniversityKarachi 75510SindhPakistan

This letter emphasizes the need to expand discussions on gut microbiome’s role in inflammatory bowel disease(IBD)and colorectal cancer(CRC)by including the often-overlooked non-bacterial components of the human gut *** highlights how viral,fungal and archaeal inhabitants of the gut respond towards gut dysbiosis and contribute to disease *** such as bacteriophages target certain bacterial species and modulate the immune *** viruses found associated include Epstein-Barr virus,human papillomavirus,John Cunningham virus,cytomegalovirus,and human herpes simplex virus type *** such as Candida albicans and Malassezia contribute by forming tissue-invasive filaments and producing inflammatory cytokines,***,mainly methanogens are also found altering the microbial fermentation *** correspondence,thus underscores the significance of considering the pathological and physiological mechanisms of the entire spectrum of the gut microbiota to develop effective therapeutic interventions for both IBD and CRC.

关键词： Gut microbiota Colorectal cancer Inflammatory bowel disease Dysbiosis Bacteriophages Methanogens Fungi

The Spherical q-Linear Diophantine Fuzzy Multiple-Criteria Group Decision-Making Based on Differential Measure

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Computer Modeling in Engineering & Sciences 2024年第2期138卷 1925-1950页

作者： Huzaira Razzaque shahzaib Ashraf Muhammad Naeem Yu-Ming Chu Institute of Mathematics Khwaja Fareed University of Engineering&Information TechnologyRahim Yar Khan64200Pakistan Department of Mathematics Deanship of Applied SciencesUmm Al-Qura UniversityMeccaSaudi Arabia Department of Mathematics Huzhou UniversityHuzhou313000China

Spherical q-linearDiophantine fuzzy sets(Sq-LDFSs)provedmore effective for handling uncertainty and vagueness in multi-criteria decision-making(MADM).It does not only cover the data in two variable parameters but is also beneficial for three parametric *** Pythagorean fuzzy sets,the difference is calculated only between two parameters(membership and non-membership).According to human thoughts,fuzzy data can be found in three parameters(membership uncertainty,and non-membership).So,to make a compromise decision,comparing Sq-LDFSs is *** measures of different fuzzy sets do,however,can have several flaws that can lead to counterintuitive *** instance,they treat any increase or decrease in the membership degree as the same as the non-membership degree because the uncertainty does not change,even though each parameter has a different *** the Sq-LDFSs comparison,this research develops the differentialmeasure(DFM).Themain goal of the DFM is to cover the unfair arguments that come from treating different types of FSs opposing criteria *** to their relative positions in the attribute space and the similarity of their membership and non-membership degrees,two Sq-LDFSs formthis preference connectionwhen the uncertainty remains same in both *** to the degree of superiority or inferiority,two Sq-LDFSs are shown as identical,equivalent,superior,or inferior over one *** suggested DFM’s fundamental characteristics are *** on the newly developed DFM,a unique approach tomultiple criterion group decision-making is *** suggestedmethod verifies the novel way of calculating the expert weights for Sq-LDFSS as in *** proposed technique in three parameters is applied to evaluate solid-state drives and choose the optimum photovoltaic cell in two applications by taking uncertainty parameter *** method’s applicability and validity shown by the findings are contrasted with those obtained using various

关键词： Multi-criteria group decision-making spherical q-linear Diophantine fuzzy sets differencemeasures photovoltaic cells medical diagnosis

Autologous hematopoietic stem cell transplantation conditioning regimens and chimeric antigen receptor T cell therapy in various diseases

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World Journal of Transplantation 2024年第1期14卷 32-41页

作者： shahzaib Maqbool Maryam Farhan Baloch Muhammad Abdul Khaliq Khan Azeem Khalid Kiran Naimat Department of Medicine Holy Family HospitalRawalpindi 46000Pakistan Department of Community Medicine Allama Iqbal Medical CollegeLahore 45000Pakistan Department of Community Dentistry Baqai Medical UniversityKarachi 43000Pakistan Department of Medicine Allama lqbal Medical CollegeLahore 45000Pakistan Department of MedicineLiaquat University of Medical and Health Sciences Karachi 43000Pakistan

Conditioning regimens employed in autologous stem cell transplantation have been proven useful in various hematological disorders and underlying malignancies;however,despite being efficacious in various instances,negative consequences have also been *** conditioning regimens were extracted from various literature searches from databases like PubMed,Google scholar,EMBASE,and *** regimens for each disease were compared by using various end points such as overall survival(OS),progression free survival(PFS),and leukemia free survival(LFS).Variables were presented on graphs and analyzed to conclude a more efficacious conditioning *** multiple myeloma,the most effective regimen was high dose melphalan(MEL)given at a dose of 200/mg/*** comparative results of acute myeloid leukemia were presented and the regimens that proved to be at an admirable position were busulfan(BU)+MEL regarding OS and BU+VP16 regarding *** case of acute lymphoblastic leukemia(ALL),BU,fludarabine,and etoposide(BuFluVP)conferred good disease control not only with a paramount improvement in survival rate but also low risk of ***,for ALL,chimeric antigen receptor(CAR)T cell therapy was preferred in the context of better OS and *** respect to Hodgkin’s lymphoma,mitoxantrone(MITO)/MEL overtook carmustine,VP16,cytarabine,and MEL in view of PFS and vice versa regarding ***-Hodgkin’s lymphoma patients were administered MITO(60 mg/m2)and MEL(180 mg/m2)which showed promising ***,amyloidosis was considered,and the regimen that proved to be competent was MEL 200(200 mg/m2).This review article demonstrates a comparison between various conditioning regimens employed in different diseases.

关键词： Conditioning regimens Multiple myeloma Lymphoma Hodgkin Non-Hodgkin Acute leukemia

Complex Decision Modeling Framework with Fairly Operators and Quaternion Numbers under Intuitionistic Fuzzy Rough Context

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Computer Modeling in Engineering & Sciences 2024年第5期139卷 1893-1932页

作者： Nadeem Salamat Muhammad Kamran shahzaib Ashraf Manal Elzain Mohammed Abdulla Rashad Ismail Mohammed M.Al-Shamiri Institute of Mathematics Khwaja Fareed University of Engineering&Information TechnologyRahim Yar Khan64200Pakistan Department of Mathematics Thal University BhakkarPunjab30000Pakistan Department of Mathematics Faculty of Science and ArtsKing Khalid UniversityMuhayl Assir61913Saudi Arabia

The main goal of informal computing is to overcome the limitations of hypersensitivity to defects and uncertainty while maintaining a balance between high accuracy,accessibility,and *** paper investigates the potential applications of intuitionistic fuzzy sets(IFS)with rough sets in the context of sparse *** it comes to capture uncertain information emanating fromboth upper and lower approximations,these intuitionistic fuzzy rough numbers(IFRNs)are superior to intuitionistic fuzzy sets and pythagorean fuzzy sets,*** use rough sets in conjunction with IFSs to develop several fairly aggregation operators and analyze their underlying *** present numerous impartial laws that incorporate the idea of proportionate dispersion in order to ensure that the membership and non-membership activities of IFRNs are treated equally within these *** operations lead to the development of the intuitionistic fuzzy rough weighted fairly aggregation operator(IFRWFA)and intuitionistic fuzzy rough ordered weighted fairly aggregation operator(IFRFOWA).These operators successfully adjust to membership and non-membership categories with fairness and *** highlight the unique qualities of these suggested aggregation operators and investigate their use in the multiattribute decision-making *** use the intuitionistic fuzzy rough environment’s architecture to create a novel strategy in situation involving several decision-makers and non-weighted ***,we developed a novel technique by combining the IFSs with quaternion *** establish a unique connection between alternatives and qualities by using intuitionistic fuzzy quaternion numbers(IFQNs).With the help of this framework,we can simulate uncertainty in real-world situations and address a number of decision-making *** the examples we have released,we offer a sophisticated and systematically constructed illustrative scenario that is intricately wo

关键词： Intuitionistic fuzzy set quaternion numbers fuzzy logic decision-making rough set

Auto-tuning PVT data using multi-objective optimization: Application of NSGA-Ⅱ algorithm

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Petroleum 2024年第1期10卷 135-149页

作者： Abdolhadi Zarifi mohammad Madani mohammad Jafarzadegan Reservoir Engineering Systems Petroleum Engineering Department Main Office Building of National Iranian South Oil Company (NISOC) Combined Planning Management National Iranian Oil Company (NIOC) Reservoir Engineering Division Petroleum Engineering Department Petroleum Engineering and Development Company (PEDEC)

Reservoir simulation is known as perhaps the most widely used, accurate, and reliable method for field development in the petroleum industry. An integral part of a reliable reservoir simulation process is to consider robust and rigorous tuned EOS models. Traditionally, EOS models are tuned iteratively through arduous workflows against experimental PVT data. However, this comes with a number of drawbacks such as forcingly using weight factors, which upon alteration adversely affects the optimization *** objective of the current work is thus to introduce an auto-tune PVT matching tool using NSGA-II multi-objective optimization. In order to illustrate the robustness of the presented technique, three different PVT samples are used, including two black-oil and one gas condensate sample. We utilize PengRobinson EOS during all the manual and auto-tuning processes. Comparison of auto-tuned EOS-generated results with those of experimental and computed statistical error values for these samples clearly show that the proposed method is robust. In addition, the proposed method, contrary to the manual matching process, provides the engineer with several matched solutions, which allows them to select a match based on the engineering background to be best amenable to the problem at hand. In addition, the proposed technique is fast, and can output several solutions within less time compared to the traditional manual matching method.

关键词： Auto-tuning PVT Equation of state NSGA-II Multi-objective optimization

Investigation of material composition,design,and performance of open-graded asphalt mixtures for semi-flexible pavement:A comprehensive experimental study

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Journal of Traffic and Transportation Engineering(English Edition) 2024年第1期11卷 92-116页

作者： mohammad Taghipoor Abolfazl Hassani mohammad M.Karimi Department of Civil and Environmental Engineering Tarbiat Modares UniversityTehranIran

The primary goal of this study is the design and construction of semi-flexible pavement(SFP)mixture in accordance with the engineering and mechanical *** study involves the use of a range of gradation curves,air void contents,cellulose and synthesized fibers,and neat and modified asphalt binders to prepare the open-graded asphalt(OGA)*** analyze the characteristics of these mixtures,a variety of test,namely binder drainage,semi-circular bending(SCB),Cantabro,wheel tracking,indirect tensile strength(ITS),and permeability tests were ***,to analyze the prepared grouting material,flexural strength,compressive strength,and fluidity tests were *** the final stage,SFP was compared to HMA in terms of engineering characteristics and *** to the results,SFP was more resistant to skid,rutting,fire,and moisture damage,while HMA had a better performance in fracture tests,including SCB *** to the results of the mechanical performance tests conducted on OGA mixtures,the highest and lowest values for air void content to achieve the highest mechanical performance level were 30%-35%and 25%,***,based on the laboratory results,it was determined that the required void ratio for constructing OGA mixtures was 24%-26%based on the bitumen type and fibers amount in the ***,SFP mixture can be regarded as a viable alternative to common pavements thanks to its high resistance to rutting and moisture damage,long freezing-thawing fatigue life,and adequate fire and skid resistance.

关键词： Semi-flexible pavement mixture Open-graded asphalt mixture Engineering properties Cantabro test Hot mix asphalt

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Recent Progress in Bionic Hydrogels for Articular Cartilage:Tribological and Mechanical Characteristics

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Journal of Bionic Engineering 2024年第2期21卷 653-673页

作者： mohammad Javan Almasi Dangsheng Xiong School of Materials Science and Engineering Nanjing University of Science and TechnologyNanjing210094China

Cartilage regeneration and repair are considered clinical challenges since cartilage has limited capability for *** tissue-engineered materials have the ability to repair cartilage,they have weak mechanical characteristics and cannot resist long-term *** the other hand,surgery to replace the joint is frequently done to treat significant cartilage deterioration these ***,the materials that are being used for replacement have high friction coefficients,lack shock absorption functions,and lack *** research on natural articular cartilage structure and function may lead to bionic hydrogels,which have suitable physicochemical and biological characteristics(e.g.,tribological and mechanical properties and the ability to support loadbearing capability),but need *** on their tribological and mechanical characteristics,the current review highlights the most recent advancements of bionic hydrogels used for articular cartilage,highlighting both the field's recent progress and its potential for future *** this reason,firstly,some important property improvement methods of bionic hydrogels are discussed and then,the recent findings of various research on the making of those bionic materials are provided and *** seems that by using some modifications such as product design,surface treatments,animal tests,controlling the isoelectric point of hydrogels,and computer simulation,the intended mechanical and tribological characteristics of natural articular cartilage may be attained by the bionic hydrogels.

关键词： Bionic hydrogel Articular cartilage Mechanical property Tribological property Lubrication

Ultrasensitive plasmonic sensor based on MDM waveguide containing Persian Orsi window cavities for refractive index and blood plasma sensing

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Optoelectronics Letters 2024年第7期20卷 406-411页

作者： mohammad Ghanavati mohammad Azim Karami School of Electrical Engineering Iran University of Science and TechnologyTehran 16846-13114Iran12

We developed a plasmonic refractive index(RI)with a metal-dielectric-metal(MDM)structure that utilizes two Persian Orsi windows-like separated cavities with a high figure of merit(FoM)and *** simulated and optimized Ag-air-Ag MDM sensor for surface plasmon resonance(SPR)offers high RI sensitivity(SRI)and the ability to detect blood plasma concentration(BPC).The results verified that structural parameters have an effect on SRI,full width at half maximum(FWHM),FoM,sensitivity of blood plasma(Sp)for right and left peaks,whose values are 1345.45 nm·RIU−1,32 nm,42.04 RIU−1,0.26 and 0.19 nm·L·g-1,*** proposed design opens a new horizon in sensor development.

关键词： index utilize MDM

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Enhanced adaptive nonlinear extended state observer for pure feedback systems with matched and mismatched disturbances

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Control Theory and Technology 2024年第2期22卷 254-268页

作者： Mahtab Delpasand mohammad Farrokhi School of Electrical Engineering Iran University of Science and TechnologyTehran16846-13114Iran Center of Excellence for Modelling and Control of Complex Systems Iran University of Science and TechnologyTehran16846-13114Iran

In this paper, an enhanced adaptive nonlinear extended state observer (EANESO) for single-input single-output pure feedback systems in the presence of external time-varying disturbances is proposed. In this paper, a nonlinear system with matched and mismatched disturbances is considered. The conventional extended state observer (ESO) can only be applied to systems that are in the form of integral chains. Moreover, this method has limitations in the face of mismatched disturbances. In the presence of time-varying disturbances, the traditional ESOs cannot estimate the disturbances accurately. To overcome this limitation, an EANESO is proposed in this paper. The main idea is to design the nonlinear ESO (NESO) to estimate the states of the system and multiple disturbances simultaneously. The observer gains are considered time-varying and adjusted with adaptation laws to improve the estimation accuracy and overcome the peaking phenomenon. Next, the proposed controller is designed based on output feedback to eliminate the effects of multiple disturbances and stabilize the closed-loop system. Subsequently, the stability analysis of the closed-loop system and convergence of the observer error are discussed. Finally, the proposed method is applied to the inverted pendulum system. The simulated results show good performance of the proposed method as compared with a recently published scheme in the related literature.

关键词： Nonlinear extended state observer Enhanced adaptive extended state observer Adaptation law Multiple-channel disturbances Inverted pendulum system Time-varying gain

The modeling non-sequential double ionization of helium atom under highintensity femtosecond laser pulses with shielding charge approximation

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Communications in Theoretical Physics 2024年第2期76卷 151-156页

作者： Marjan Zakavi mohammad Sabaeian Department of Physics Faculty of ScienceShahid Chamran University of AhvazIran Center for Research on Laser and Plasma Shahid Chamran University of AhvazIran

In this study,we successfully extracted the‘knee structure’for non-sequential double ionization(NSDI)in the helium *** achieve this,for the first time,we solved the time-dependent Schrödinger equation in three dimensions for the helium atom,utilizing the shielding charge *** findings corroborate prior observations by Wang et al[Wang and Eberly,***.105,083001(2010)],demonstrating that NSDI occurs within a narrower time window in circular polarization compared to linear *** a result,the yield of linear polarization was higher than that of circular polarization,aligning with the previously reported ***,in the case of circular polarization,the time window further narrows with increasing intensity,attributed to a decrease in the time-of-flight.

关键词： NSDI knee structure TDSE shielding charge helium 3D-TDSE

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