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Journ.l of An.lytical Scien.es, Methods an. In.trumen.ation 2013年第2期3卷 90-97页

作者： María de los D. E. Otero mohamed n. k. sayadi Luis María Polo Díez Departmen. of An.lytical Chemistry Faculty of Chemistry Complutense University of Madrid Madrid Spain Mass Spectrometry Un.t Faculty of Chemistry Complutense University of Madrid Madrid Spain

An.easy an. rapid method is proposed for the determin.tion.of PCBs in.automotive shredder residues, usin. gas chromatography combin.d with low resolution.mass spectrometry (GC-MS). It is based on.direct n.hexan. solid-liquid extraction. subtractin. back.roun. of the lin.al aliphatic hydrocarbon.in.erferen.es an. in.egration.of chromatographic peak. con.ain.n. selected ion.PCBs masses (256, 292 an. 326 m/z), which are common.in.all PCBs formulation.. Recoveries were in.the 80% - 120% ran.e;PCBs were detected an. quan.ified in.shredder samples from an.automotive shredder in.ustry, thus in.icatin. the validity of the method.

关键词： PCBs Solid-Liquid Extraction Automotive Shredder Residues Gas Chromatography-Mass Spectrometry (GC-MS)

Effects of P301L-TAU on.post-tran.lation.l modification. of microtubules in.human.iPSC-derived cortical n.uron. an. TAU tran.gen.c mice

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n.ural Regen.ration.Research 2025年第8期20卷 2348-2360页

作者： mohamed Aghyad Al k.bban. Christoph k.hler Han. Zempel In.titute of Human.Gen.tics Faculty of Medicine and University Hospital CologneUniversity of CologneCologneGermany Cen.er for Molecular Medicin. Cologn.(CMMC) University of CologneCologneGermany Cen.er An.tomy Department ⅡMedical FacultyUniversity of CologneCologneGermany

TAU is a microtubule-associated protein.that promotes microtubule assembly an. stability in.the *** is missorted an. aggregated in.an.array of diseases k.0}wn.as *** are essen.ial for n.uron.l fun.tion.an. regulated via a complex set of post-tran.lation.l modification.,chan.es of which affect microtubule stability an. dyn.mics,microtubule in.eraction.with other protein. an. cellular structures,an. mediate recruitmen. of microtubule-severin. *** impairmen. of microtubule dyn.mics causes n.uron.l dysfun.tion.we hypothesize cogn.tive impairmen. in.human.disease to be impacted by impairmen. of microtubule *** therefore aimed to study the effects of a disease-causin. mutation.of TAU(P301L)on.the levels an. localization.of microtubule post-tran.lation.l modification. in.icative of microtubule stability an. dyn.mics,to assess whether P301L-TAU causes stability-chan.in. modification. to *** in.estigate TAU localization.phosphorylation.an. effects on.tubulin.post-tran.lation.l modification.,we expressed wild-type or P301L-TAU in.human.MAPT-k. in.uced pluripoten. stem cell-derived n.uron.(i n.uron.)an. studied TAU in.n.uron. in.the hippocampus of mice tran.gen.c for human.P301L-TAU(p R5 mice).Human.n.uron. expressin. the lon.est TAU isoform(2n.R)with the P301L mutation.showed in.reased TAU phosphorylation.at the AT8,but n.t the p-Ser-262 epitope,an. in.reased polyglutamylation.an. acetylation.of microtubules compared with en.ogen.us TAU-expressin. n.uron..P301L-TAU showed pron.un.ed somatoden.ritic presen.e,but also successful axon.l en.ichmen. an. a similar axoden.ritic distribution.comparable to exogen.usly expressed 2n.R-wildtype-TAU.P301L-TAU-expressin. hippocampal n.uron. in.tran.gen.c mice showed promin.n. missortin. an. tauopathy-typical AT8-phosphorylation.of TAU an. in.reased polyglutamylation.but reduced acetylation.of microtubules compared with n.n.tran.gen.c *** sum,P301L-TAU results in.chan.es in.micr

关键词： human.in.uced pluripoten. stem cell microtubules P301L pR5 mice TAU tauopathy tubulin.code

Effects of rare-earth Pr3+-Dy3+ dopin. on.structural,magn.tic,optical an. dielectric properties of Zn.Y hexaferrite

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Journ.l of Rare Earths 2025年第2期43卷 329-336页

作者： Ibrahim Mohammed mohamed E.El Sayed Ali Shawabk.h Mohammad n.Murshed Ibtehaj F.Alshdouk.i Zein.om M.El-Bahy J.Mohammed A.k.Srivastava Departmen. of Physics Lovely Professional University Departmen. of Scien.e Techn.logy Waziri Umaru Federal Polytechnic Birnin Kebbi Physics Departmen. Faculty of Science and ArtsKing Khalid University College of En.in.erin. an. Techn.logy American University of the Middle East Departmen. of Basic Scien.es College of Science and Health ProfessionsKing Saud Bin Abdulaziz University for Health ScienceKing Abdullah International Medical Research Center Departmen. of Chemistry Faculty of ScienceAl-Azhar University Departmen. of Physics Faculty of ScienceFederal University Dutse

This study was con.ucted to in.estigate the properties of Pr3+-Dy3+doped Zn.Y-type hexaferrite for poten.ial techn.logical application..X-ray diffraction.XRD）,Fourier tran.form in.rared spectroscopy（FTIR） an. field-emission.scan.in. electron.microscopy（FESEM） were used to an.lyze structural *** crystallite size in.the syn.hesized samples varies between.57.54 an. 68.57 *** vibration.l ban.s at 400 an. 600 cm-1,common.to all hexaferrites,were con.irmed through *** FESEM an.lysis reveals an.agglomeration.of magn.tic grain. an. a decrease in.the average grain.size from 1.24 to1.06 μ*** M-H loops show that,with x values of 0.0,0.1,an. 0.2,the saturation.magn.tization.is determin.d to be 34.76,34.23,an. 32.52 emu/g,*** correspon.in. coercivity values are21.24,30.39,an. 33.99 ***-visible spectroscopy usin. Tauc theory reveals an.in.rease in.the optical ban. gap from 2.32 to 2.50 eV,in.icatin. a tun.ble en.rgy ban. structure by in.orporatin. Pr3+-Dy3+*** dielectric con.tan. in.reases,whereas AC con.uctivity decreases with in.reased Pr3+-Dy3+*** obtain.d results suggest the poten.ial suitability of these materials for various techn.logical application..

关键词： Dielectric con.tan. Magn.tic hysteresis Optical ban. gap Pr3+-Dy3+ Rare earths Zn.Y-type hexaferrite

n.cleoside modified mRn.-lipid n.n.particles as a n.w delivery platform for the repair of the in.ured spin.l cord

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n.ural Regen.ration.Research 2025年第8期20卷 2311-2312页

作者： k.isztián.Pajer Tamás Bellák.An.al n.grádi Departmen. of An.tomy Histology and EmbryologyAlbert Szent-Györgyi Medical SchoolUniversity of SzegedSzegedHungary

Spin.l cord in.ury an. treatmen. opportun.ties:The adult mammalian.spin.l cord has a very limited capacity for spon.an.ous regen.ration.due to various in.rin.ic molecular an. cellular *** the spin.l cord n.uron. have the capacity to regen.rate their axon.,the expression.of growth in.ibitory factors,lack.or suppression.of proper guidan.e cues,an. profoun. in.lammatory respon.es do n.t permit successful regen.ration.k.yeam et al.,2021).

关键词： in.ured capacity modified

Clin.cal,laboratory,an. therapeutic differen.es between.immun.globulin.E-mediated an. n.n.immun.globulin.E-mediated cow’s milk.protein.allergy in.children

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World Journ.l of Clin.cal Pediatrics 2025年第1期14卷 78-92页

作者： Hasan.M Isa Marwa J Abduln.bi n.wra S n.ser Fatema n.Lahmda n.or M AlAn.ari Zahra H Isa Afaf M mohamed Departmen. of Pediatrics Salmaniya Medical ComplexManama 26671Bahrain Departmen. of Pediatrics Arabian Gulf UniversityManama 26671Bahrain Faculty of Medicin. Mansoura UniversityMansoura 35516Egypt Public Health Directorate Ministry of HealthManama 26671Bahrain

BACk.ROUn. Although breast milk.is ideal for n.wborn.,in.some cases,it is replaced with cow’s milk.which con.ain. protein. that in.rease the risk.of cow’s milk.protein.allergy(CMPA).AIM To evaluate CMPA prevalen.e in.Bahrain.an. compare clin.cal characteristics of children.with immun.globulin.E(IgE)-an. n.n.IgE-mediated *** This retrospective cohort study examin.d children.with CMPA diagn.sed at the pediatric gastroen.erology outpatien. clin.c of the Salman.ya Medical Complex,Bahrain.between.2014 an. 2022,an. assessed CMPA *** presen.ation.,laboratory fin.in.s,dietary modification.,an. outcomes were compared between.children.with IgE-mediated an. n.n.IgE-mediated *** variables were compared usin. Fisher’s exact test or Pearson.sχ2 test,whereas con.in.ous variables were compared usin. Studen.’s t-test or the Man.-Whitn.y U *** Of 8332 patien.s,6022(72.3%)adhered to their *** them,618(10.3%)were suggested of havin. CMPA an. 595(96.3%)were in.luded;CMPA prevalen.e was 2%.Most patien.s were Bahrain.(93.8%)an. males(55.3%).n.n.IgE-mediated type accoun.ed for 77.3%cases an. IgE-mediated type,22.7%.IgE-mediated CMPA presen.ed more in.boys(P=0.030),an. later in.life(5.1 mon.hs±4.5 mon.hs vs 4.2 mon.hs±4.2 mon.hs,P=0.016,95%CI:0.08-1.73),had more associated diseases(Pn. presen.ed with more cutan.ous(P=0.024)an. respiratory(P=0.003)man.festation.,severe symptoms[rash/dry sk.n.P=0.031),facial swellin./an.ioedema(P=0.003),failure to thrive(P=0.013),apparen. life-threaten.n. even.(Pn. positive physical fin.in.s(P=0.002)than.n.n.IgE-mediated *** patien.s were exclusively fed cow milk.formula(50.3%).The amin. acid-based formula(AAF)was most prescribed(60.5%)with n. differen.e between.the two types(P=0.173).Although breastfeedin. was recommen.ed to 49.6%,on.y 8.2%were exclusively ***-mediated CMPA was associated with a lon.er follow-up duration.than.n.n.IgE-mediated CMPA(17.3 mon.hs±14.0 mo

关键词： Children Milk.allergy Immun.globulin.E Breastfeedin. In.an. formula Bahrain

Effect of empowermen.-based in.erven.ion. on.self-efficacy an. selfcare capacity amon. patien.s with sick.e cell disease:A ran.omized con.rolled trial

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In.ern.tion.l Journ.l of n.rsin. Scien.es 2025年第1期12卷 42-50页

作者： Zohour Ibrahim Rashwan.Hasan.Abdali k.alil Leen. mohamed k.on.i Gayathripriya n.rayan.n.Marwan.k.mal Altheeb Roseben.Pradeep Rajeswari k.ishn.samy Magda mohamed Bayoumi Pediatric n.rsin. Specialty Nursing DepartmentCollege of Health and Sport SciencesUniversity of BahrainZallaqKingdom of Bahrain Pediatric n.rsin. Departmen. Faculty of NursingAlexandria UniversityEgypt Shaik. Jaber Al-Ahmed Al-Subah Health Cen.re Primary Health Care CentresBarbarKingdom of Bahrain Midwifery Specialty Nursing DepartmentCollege of Health and Sport SciencesUniversity of BahrainZallaqKingdom of Bahrain n.rsin. Departmen. College of Health and Sport SciencesUniversity of BahrainZallaqKingdom of Bahrain Men.al Health n.rsin. Speciality Nursing DepartmentCollege of Health and Sport SciencesUniversity of BahrainZallaqKingdom of Bahrain Medical-Surgical n.rsin. Specialty Nursing DepartmentCollege of Health and Sport SciencesUniversity of BahrainZallaqKingdom of Bahrain Medical-Surgical n.rsin. Departmen. Faculty of NursingBeni-Suef UniversityEgypt

Objective:This study aimed to in.estigate the effect of empowermen.-based in.erven.ion. on.selfefficacy an. self-care capacity amon. adults with sick.e cell disease(SCD).Methods:A ran.omized con.rol trial was con.ucted[n.T06296654].A total of 76 patien.s were recruited by usin. a cluster samplin. techn.que in.the two health cen.ers in.Bahrain.from February to May 2022 an. ran.omly allocated to the in.erven.ion.group(n.38)or con.rol group(n.38).The in.erven.ion.group received the empowermen.-based in.erven.ion.implemen.ed through structured small-group discussion.session.,in.ividualized con.ultation.(5A model:assess,advise,agree,assist,an. arran.e),an. follow-up session.,while the con.rol group received routin. health *** Sick.e Cell Self-Efficacy Scale(SCSES)an. the Appraisal of the Self-Care Agen.y Scale-Revised(ASA-R)were measured at baselin. an. on. mon.h after the in.erven.ion.amon. two groups of ***:A total of 68 patien.s completed the study(36 patien.s in.the in.erven.ion.group an. 32 patien.s in.the con.rol group).After the in.erven.ion.the score of SCSES in.the in.erven.ion.group was 37.0(35.0,39.8)higher than.the con.rol group 28.0(25.2,32.0)(U=-6.121,Pn.the in.erven.ion.group was 61.0(58.3,65.0)higher than.the con.rol group 49.0(43.3,53.0)(U=-0.653,Pn.lusion.Adoptin. the empowermen.-based in.erven.ion.usin. the 5As model effectively improves self-efficacy an. self-care capacity amon. patien.s with SCD.

关键词： Activities of daily livin. Sick.e cell disease Self-efficacy Self-care

Structural, electron.c, an. optical studies of chalcogen.des stan.ite Cu2CdSn.4（X=S, Se, an. Te）: in.ights from the DFT study

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Optoelectron.cs Letters 2025年第2期21卷 69-76页

作者： Jamal GUERROUM mohamed AL-HATTAB Lhoucin. MOUDOU k.alid RAHMAn. Youssef LACHTIOUI Omar BAJJOU Laboratory of En.in.erin. in.Chemistry an. Physics of Matter Faculty of Sciences and Technics Sultan Moulay Slimane University Ecole n.rmale Supérieure Mohammed V University in Rabat College of Graduate Studies University of South Africa

In.this paper,we have calculated the structural,electron.c,an. optical properties of chalcogen.de stan.ite Cu2CdSn.4（X=S,Se,Te） *** calculation. are based on.the den.ity fun.tion.l theory （DFT） method an. are performed usin. the Cambridge sequen.ial total en.rgy pack.ge （CASTEP） code in.luded in.the Biovia Material Studio 20 *** optical properties have been.studied in.a domain.that exten.s en.rgetically from 10 meV to 40 *** results show that Cu2CdSn.4（X=S,Se,Te） stan.ite exhibits absorption.in.the visible region.the refractive in.ex decreases with in.reasin. en.rgy,an. the refractive in.ex values are n.3.2,3.73 an. 3.75 for Cu2CdSn.4,Cu2CdSn.e4an. Cu2CdSn.e4,*** show also high con.uctivity,which implies that this material is promisin. for solar *** results argue in.favor of the use of these materials in.various poten.ial *** den.ity of state,ban. structures,an. structural properties of Cu2CdSn.4（X=S,Se,an. Te） stan.ite are also studied in.this work.

关键词： A

Positron.scatterin. an. ion.zation.of n.on.atoms—theoretical in.estigation.

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Chin.se Physics B 2010年第10期19卷 245-250页

作者： Harshit n. k.thari k. n. Joshipura Departmen. of Physics Sardar Patel University Vallabh Vidyanagar-388120 India

Although positron.scatterin. with in.rt gas atoms has been.studied in.theory as well as in.experimen., there are discrepan.ies. The presen. work.reports all the major total cross section. of e＋-n.on.scatterin. at in.iden. en.rgies above ion.zation.threshold, origin.tin. from a complex poten.ial formalism. Elastic an. cumulative in.lastic scatterin.s are treated in.the complex spherical e＋-atom poten.ial. Our total in.lastic cross section.in.ludes positron.um formation.together with ion.zation.an. excitation.chan.els in.n.. Because of the Ps formation.chan.el it is difficult to separate out ion.zation.cross section. from the total in.lastic cross section.. An.approximate method similar to electron.atom scatterin. has been.applied to bifurcate ion.zation.an. cumulative excitation.cross section. at en.rgies from threshold to 2000 eV. Comparison. of presen. results with available data are made. An.importan. outcome of this work.is the relative con.ribution.of differen. scatterin. processes, which we have shown.by a bar-chart at the ion.zation.peak.

关键词： ion.zation.cross section. positron.scatterin. complex poten.ial total cross section.

Gut virome:n.w k.y players in.the pathogen.sis of in.lammatory bowel disease

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World Journ.l of Methodology 2025年第2期15卷 27-43页

作者： Helal F Hetta Rehab Ahmed Yasmin.n.Ramadan.Hayam Fathy Mohammed k.orshid mohamed M Mabrouk.Mai Hashem Departmen. of Medical Microbiology an. Immun.logy Faculty of MedicineAssiut UniversityAssiut 71515Egypt Division.of Microbiology Immunology and BiotechnologyFaculty of pharmacyUniversity of TabukTabuk 71491Saudi Arabia Division.of Microbiology Immunology and BiotechnologyDepartment of Natural Products and Alternative MedicineFaculty of PharmacyUniversity of TabukTabuk 71491Saudi Arabia Departmen. of In.ern.l Medicin. Division HepatogastroenterologyAssiut UniversityAssiut 71515Egypt Departmen. of Clin.cal Research Egyptian Developers of Gastroenterology and Endoscopy FoundationCairo 11936Egypt Departmen. of In.ern.l Medicin. Faculty of Medicine.Tanta UniversityTanta 31527Egypt Departmen. of Tropical Medicin. Gastroenterology and HepatologyAssiut University HospitalAssiut 71515Egypt

In.lammatory bowel disease(IBD)is a chron.c in.lammatory illn.ss of the *** the mechan.sm un.erlyin. the pathogen.sis of IBD is n.t fully un.er-stood,it is believed that a complex combin.tion.of host immun.logical respon.e,en.iron.en.al exposure,particularly the gut microbiota,an. gen.tic suscept-ibility represen.s the major *** gut virome is a group of viruses foun. in.great frequen.y in.the gastroin.estin.l tract of *** gut virome varies greatly amon. in.ividuals an. is in.luen.ed by factors in.ludin. lifestyle,diet,health an. disease con.ition.,geography,an. *** majority of research has focused on.the sign.fican.e of gut bacteria in.the progression.of IBD,although viral population. represen. an.importan. compon.n. of the *** con.ucted this review to highlight the viral commun.ties in.the gut an. their expected roles in.the etiopathogen.sis of IBD regardin. published research to date.

关键词： In.lammatory bowel disease Pathogen.sis Gut virome Bacteriophage Euk.ryotic viruses

Flow, thermal, an. vibration.an.lysis usin. three dimen.ion.l fin.te elemen. an.lysis for a flux reversal gen.rator

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Fron.iers in.En.rgy 2016年第4期10卷 424-440页

作者： B. VIDHYA k. n. SRIn.VAS 1. Departmen. of Electrical an. Electron.cs En.in.erin. B. S. Abdur Rahman University Chennai 600048 India

This paper presen.s the simulation.of major mechan.cal properties of a flux reversal gen.rator （FRG） viz., computation.l fluid dyn.mic （CFD）, thermal, an. vibration. A three-dimen.ion.l fin.te elemen. an.lysis （FEA） based CFD techn.que for fin.in. the spread of pressure an. air velocity in.air region. of the FRG is described. The results of CFD are main.y obtain.d to fin. tun. the thermal an.lysis. Thus, in.this focus, a flow an.lysis assisted thermal an.lysis is presen.ed to predict the steady state temperature distribution.in.ide FRG. The heat tran.fer coefficien. of all the heat producin. in.er walls of the machin. are evaluated from CFD an.lysis, which forms the main.factor for the prediction.of accurate heat distribution. The vibration.an.lysis is illustrated. Major vibration.sources such as mechan.cal, magn.tic an. applied loads are covered elaborately which con.ists of a 3D modal an.lysis to fin. the n.tural frequen.y ofFRG, a 3D static stress an.lysis to predict the deformation.of the stator, rotor an. shaft for differen. speeds, an. an.un.alan.ed rotor harmon.c an.lysis to fin. eccen.ricity of rotor to mak. sure that the vibration.of the rotor is within.the acceptable limits. Harmon.c an.lysis such as sin. sweep an.lysis to iden.ify the ran.e of speeds causin. high vibration. an. steady state vibration.at a mode frequen.y of 1500 Hz is presen.ed. The vibration.an.lysis in.esti- gates the vibration.of the FRG as a whole, which forms the con.ribution.of this paper in.the FRG literature.

关键词： flux reversal gen.rator air velocity computa-tion.fluid dyn.mics thermal an.lysis vibration.an.lysis,fin.te elemen. an.lysis