Gut virome:New key players in the pathogenesis of inflammatory bowel disease
作者机构：Department of Medical Microbiology and ImmunologyFaculty of MedicineAssiut UniversityAssiut 71515Egypt Division of MicrobiologyImmunology and BiotechnologyFaculty of pharmacyUniversity of TabukTabuk 71491Saudi Arabia Division of MicrobiologyImmunology and BiotechnologyDepartment of Natural Products and Alternative MedicineFaculty of PharmacyUniversity of TabukTabuk 71491Saudi Arabia Department of Internal MedicineDivision HepatogastroenterologyAssiut UniversityAssiut 71515Egypt Department of Clinical ResearchEgyptian Developers of Gastroenterology and Endoscopy FoundationCairo 11936Egypt Department of Internal MedicineFaculty of Medicine.Tanta UniversityTanta 31527Egypt Department of Tropical MedicineGastroenterology and HepatologyAssiut University HospitalAssiut 71515Egypt
出 版 物：《World Journal of Methodology》 (世界方法学杂志（英文）)
年 卷 期：2025年第15卷第2期
页 面：27-43页
学科分类：1007[医学-药学(可授医学、理学学位)] 100705[医学-微生物与生化药学] 1001[医学-基础医学(可授医学、理学学位)] 100103[医学-病原生物学] 10[医学]
主 题：Inflammatory bowel disease Pathogenesis Gut virome Bacteriophage Eukaryotic viruses
摘 要：Inflammatory bowel disease(IBD)is a chronic inflammatory illness of the *** the mechanism underlying the pathogenesis of IBD is not fully under-stood,it is believed that a complex combination of host immunological response,environmental exposure,particularly the gut microbiota,and genetic suscept-ibility represents the major *** gut virome is a group of viruses found in great frequency in the gastrointestinal tract of *** gut virome varies greatly among individuals and is influenced by factors including lifestyle,diet,health and disease conditions,geography,and *** majority of research has focused on the significance of gut bacteria in the progression of IBD,although viral populations represent an important component of the *** conducted this review to highlight the viral communities in the gut and their expected roles in the etiopathogenesis of IBD regarding published research to date.
维普期刊数据库