检索结果-南通市图书馆

Gastro-duodenal disease in Africa: Literature review and clinical data from Accra, Ghana

World j.urnal of Gastroenterology 2019年第26期25卷 3344-3358页

作者： Timothy N Archampong Richard H Asmah Cathy j.Richards Vicki j.Martin Christopher D Bayliss edília Botao Leonor David Sandra Beleza Carla Carrilho Department of Medicine and Therapeutics School of Medicine and DentistryUniversity of GhanaAccra Box 4236Ghana Department of Genetics and Genome Biology University of LeicesterLeicester LE1 7RHUnited Kingdom Department of Medical Laboratory Sciences School of Biomedical and Allied Health SciencesUniversity of GhanaAccra Box 4236Ghana Department of Histopathology Leicester Royal InfirmaryLeicester LE1 5WWUnited Kingdom Department of Pathology Maputo Central HospitalMaputo POBox 1164Mozambique Department of Pathology Medical Faculty of the University of PortoPorto 4200-465Portugal Institute of Molecular Pathology and immunology at the University of Porto(Ipatimup) Porto 4200-465Portugal Instituto de Investigacao e Inovacao em Saude(i3S) University of PortoPorto 4200-465Portugal Department of Pathology Faculty of MedicineEduardo Mondlane UniversityMaputo POBox 257Mozambique

Gastroduodenal disease(GDD)was initially thought to be uncommon in *** others,lack of access to optimal health infrastructure and suspicion of conventional medicine resulted in the reported prevalence of GDD being significantly lower than that in other areas of the *** the increasing availability of flexible upper gastro-intestinal endoscopy,it has now become apparent that GDD,especially peptic ulcer disease(PUD),is prevalent across the continent of *** risk factors for gastric cancer(GCA)include Helicobater pylori(***),diet,Epstein-Barr virus infection and industrial chemical exposure,while those for PUD are ***,non-steroidal antiinflammatory drug(NSAID)-use,smoking and alcohol *** these,*** is generally accepted to be causally related to the development of atrophic gastritis(AG),intestinal metaplasia(im),PUD and distal ***,we perform a systematic review of the patterns of GDD across Africa obtained with endoscopy,and complement the analysis with new data obtained on premalignant gastric his-topathological lesions in Accra,Ghana which was compared with previous data from Maputo,*** there is a general lack of structured cohort studies in Africa,we also considered endoscopy-based hospital or tertiary centre studies of symptomatic *** Africa,there is considerable heterogeneity in the prevalence of PUD with no clear geographical ***,there are differences in PUD within-country despite universally endemic *** *** is not uncommon in *** of the African tertiary-centre studies had higher prevalence of PUD when compared with similar studies in western *** additional intriguing observation is a recent,ongoing decline in PUD in some African countries where *** infection is still *** possible reason for the high,sustained prevalence of PUD may be the significant use of NSAIDs in local or over-the-counter *** prevalence

关键词： Gastroduodenal Peptic ulcer Gastric cancer Africa Pre-malignant Atrophy Intestinal metaplasia Duodenal ulcer Gastric ulcer

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

慢性肾脏病患者血压与动脉僵硬度的昼夜变化:内皮素1的作用

引用

中华高血压杂志 2014年第7期22卷 685-685页

作者：赵狄叶鹏 Dhaun N Moorhouse R MacIntyre im Melville V Oosthuyzen W Kimmitt RA Brown KE Kennedy ed Goddard j.Webb Dj

高血压与动脉僵硬是慢性肾脏病重要的心血管危险因素，内皮素1可促进此过程；夜间血压杓型消失与慢性肾脏病进展相关，但目前尚无24h动脉僵硬度变化的研究资料。研究人员纳入健康志愿者及慢性肾脏病患者（n=15），观察其24h血压、动脉... 详细信息

高血压与动脉僵硬是慢性肾脏病重要的心血管危险因素，内皮素1可促进此过程；夜间血压杓型消失与慢性肾脏病进展相关，但目前尚无24h动脉僵硬度变化的研究资料。研究人员纳入健康志愿者及慢性肾脏病患者（n=15），观察其24h血压、动脉僵硬度和内皮素系统变化，

关键词：动脉僵硬度慢性肾脏病内皮素1 高血压昼夜变化患者心血管危险因素健康志愿者

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

控制性自然体外受精可能是反复性不明原因胚泡着床不全和子宫高自然杀伤细胞计数患者可供选择的方法

引用

世界核心医学期刊文摘（妇产科学分册） 2005年第2期1卷 28-28页

作者： L?ed? ee-Bataille N. Dubanchet S. Kadoch j. 党慧敏 INSERM Unit?e 131 Cla-martFrance

Patients with a history of repeated a nd unexplained im-plantation failure after IVF-embry o transfer and a high u-terine natural killer cell count dur ing estrogen-progestin treatment may bene-fit from controlled nat... 详细信息

关键词：体外受精胚泡着床自然杀伤细胞孕激素治疗

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

神经生长因子-酪氨酸激酶A途径参与人体体温和应激调节:对遗传性感觉异常和自发性Ⅳ型神经病变患者的研究

引用

世界核心医学期刊文摘（儿科学分册） 2005年第8期1卷 60-61页

作者： Loewenthal N. Levy j. Schreiber R. E. Hershkovitz 王经纬 Pediatric Department Soroka Medical Center POB 151 Beer Sheva 84101 Israel Dr.

Hereditary sensory and autonomie neuropathy type IV (HSAN IV) is caused by mu tations in the tyrosin kinase A (TrkA) gene, encoding for the high- affinity re ceptor of nerve growth factor (NGF). The NGF- TrkA system is expressed in many endocrine glands. We hypothesized that HSAN IV represents a natural model for im paired NGF effect on the neuroendocrine system in humans. We have documented the clinical outcome of 31 HSAN IV patients in a single medical center, and investi gated their basal endocrine system status. The endocrine system response to thir st was compared between six patients and six healthy children. High rates of mor tality (22% ) and severe morbidity (30% ) have been found in HSAN IV patients. Hypothermia was noted in 40% of the patients and unexplained fever was observ ed in 56% . Subnormal adrenal function was demonstrated in six (30% ) of the p atients studied. Furthermore, we found lower plasma norepinephrine (NE) levels i n six HSAN IV patients compared with a control group after the thirst test. Our findings emphasize the importance of NGF- TrkA pathway in the physiology of the neuroendocrine system and its response to stress. Inadequate response to stress might contribute to the observed significant mortality, morbidity, and temperat ure instability in HSAN IV patients.

关键词：感觉异常神经生长因子人体体温内分泌系统 TrkA 内分泌腺体水平比对高亲和力受体肾上腺功能低体温

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

黄冈公铁两用长江大桥桥塔液压爬模施工技术

引用

世界桥梁 2015年第1期43卷 18-22页

作者：尹振君中铁大桥局集团第五工程有限公司江西九江332001

黄冈公铁两用长江大桥桥塔为H形钢筋混凝土结构,塔高190.5m,采用液压爬模法施工。为满足液压爬模在高塔施工过程中快速化施工的需求并确保施工安全,针对桥塔结构特点,选用将5m节段液压爬模改进成6m的节段液压爬模进行桥塔施工,并对液压... 详细信息

黄冈公铁两用长江大桥桥塔为H形钢筋混凝土结构,塔高190.5m,采用液压爬模法施工。为满足液压爬模在高塔施工过程中快速化施工的需求并确保施工安全,针对桥塔结构特点,选用将5m节段液压爬模改进成6m的节段液压爬模进行桥塔施工,并对液压爬模结构进行优化改进,包括整体制作大装饰槽和大倒角模板并固定在液压爬模上,在大装饰槽处附墙装置下增加牛腿,将塔柱内、外侧面液压爬模上支架后移平台加长50cm。通过合理布置桥塔液压爬模轨迹,桥塔液压爬模只在中下塔柱转角处进行1次转换,避免了液压爬模在高空中多次转换的风险;液压爬模采用分组整体转换,加快了桥塔施工速度。实践证明,该桥采用液压爬模施工技术,实现了高效快速化施工目标,且施工过程安全。

关键词：斜拉桥桥塔液压爬模选型改进施工技术

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

双胞胎和三胞胎与单胎比较:多胎和发育对新生儿结局的影响

引用

世界核心医学期刊文摘（妇产科学分册） 2005年第2期1卷 7-8页

作者： Garite T.j. Clark R.H. Elliott j.P. Thorp j.A. 兰玲 Dept.of Obstetrics and Gyne colog y University of CaliforniaIrvine Me dical Center101The City DrOrang eCA 92863-1491Unit ed States Dr.

Obj.ctive Information on outcome by gestational age fromlarge numbers of twins and triplets i s limited and is im-portant for counseling and decision-making in obstetric *** reviewed one of the larg est available neonatal databases to describe mortality and morbidity rates and growth in newborn infants from multiple gestations and compared these data with data for sin *** design Data from a large prospectively recorded neonatal database that incorporated neonatal records from j.nuary 1997to j.ly 2002were *** evaluate d birth weight and neonatal mortality and morbidity ra tes that affected long -term outcome for each week of gestational age from 23to35weeks of gestation for all nonanom olous inborn twins and triplets who were admitted to the neonatal intensive care unit and compared these data to all singletons who met similar criteria during the same tim e *** Therewere 12,302twin and 2155triplet bir ths that met the entry *** data for these newborn infants were compared with 36,*** bir th weights at each gestational week were similar for all gestational ages until29weeks of gestation for triplets an d 32weeks of gestation for *** these gestational ages,the entire difference between twins and singletons was due to the weight of the smaller twin;the larger twins’mean weights were similar to singletons at all weeks that were s *** order at each week also did not affect neonata l mortality rates,even when corrected for route of delivery and antenatal *** morbidities associated wi th adverse long -term outcomes(intraventricular hemorrhage,reti nopathy of prematurity,necrotizing enteroco litis)were also not dif-ferent between multiple infants and *** growth restriction(IUGR)was associated with increased mortality rates at all gestational ages,but in the absences of IUGR,discordance was *** Data on a large number of twins and triplets provide reass

关键词：新生儿结局新生儿死亡率单胎妊娠平均出生体重生长发育情况数据库资料视网膜疾病脑室内出血咨询指导胎孕

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Physical activity in primary and secondary prevention of cardiovascular disease:Overview updated

引用

World j.urnal of Cardiology 2016年第10期8卷 575-583页

作者： Alberto j.Alves j.ao L Viana Suiane L Cavalcante Nórton L Oliveira j.séA Duarte j.rge Mota j.séOliveira Fernando Ribeiro Research Centre in Sports Sciences Health and Human DevelopmentCIDESDUniversity Institute of Maia Research Center in Physical Activity Health and LeisureCIAFELFaculty of SportUniversity of Porto School of Health Sciences and Institute of Biomedicine iB iM EDUniversity of Aveiro

Although the observed progress in the cardiovascular disease treatment, the incidence of new and recurrent coronary artery disease remains elevated and constitutes the leading cause of death in the developed countries. Three-quarters of deaths due to cardiovascular diseases could be prevented with adequate changes in lifestyle, including increased daily physical activity. New evidence confirms that there is an inverse dose-response relationship between physical activity and cardiovascular disease and mortality risk. However, participation in moderate to vigorous physical activity may not fully attenuate the independent effect of sedentary activities on increased risk for cardiovascular diseases. Physical activity also plays an important role in secondary prevention of cardiovascular diseases by reducing the impact of the disease, slowing its progress and preventing recurrence. Nonetheless, most of eligible cardiovascular patients still do not benefit from secondary prevention/cardiac rehabilitation programs. The present review draws attention to the importance of physical activity in the primary and secondary prevention of cardiovascular diseases. It also addresses the mechanisms by which physical activity and regular exercise can improve cardiovascular health and reduce the burden of the disease.

关键词： Physical activity Primary prevention Secondary prevention Cardiovascular disease Health care evaluation mechanisms

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

纸浆模塑的缓冲特性

引用

株洲工学院学报 1995年第4期9卷 8-14页

作者： D.G.Eagleton j.A.Marcondes 金潇明株洲工学院株洲412008

本文绘制了纸浆模塑材料的缓冲曲线图,并与聚苯乙烯泡沫塑料(EPS)的曲线图进行了比较。纸浆模塑材料的某些缓冲特性是由于将其模塑成多个“窝状”波纹纸浆板所形成的。当纸浆模塑材料发生撞击时,这些“窝状”波纹发生相互碰撞而减缓了... 详细信息

本文绘制了纸浆模塑材料的缓冲曲线图,并与聚苯乙烯泡沫塑料(EPS)的曲线图进行了比较。纸浆模塑材料的某些缓冲特性是由于将其模塑成多个“窝状”波纹纸浆板所形成的。当纸浆模塑材料发生撞击时,这些“窝状”波纹发生相互碰撞而减缓了冲击。研究结果表明,纸浆模塑试样对于低静载、低跌落高度及一次性冲击具有良好的缓冲特性。但是,这种材料的缓冲特性在5kPa(千帕)以上的静载时。以及大跌落高度或多次性冲击条件下就比EPS的差。通过两个试样的“窝状”波纹相互叠合后,这些特性就能得到改善。可以得出这样结论,这种材料在某些情况下具有代替EPS的潜力,本文还为将来的研究工作提出了某些建议。

关键词：纸浆模塑缓冲减震吸收冲击

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

薄钢管-防火涂料-CFRP修复受损钢筋混凝土柱的抗火性能试验研究

引用

辽东学院学报（自然科学版） 2017年第4期24卷 276-285页

作者：赵英杰沈阳建筑大学土木工程学院沈阳110168

为研究完全破坏的钢筋混凝土柱子修复和增强其防火性能,利用高温燃烧炉对四面受火的试件高温下性能探究分析,将所得到的结果与钢筋混凝土柱子的计算承载力进行比较。使用薄钢管-防火涂料-CFRP共同加固完全破坏的钢筋混凝土柱子,得到了... 详细信息

为研究完全破坏的钢筋混凝土柱子修复和增强其防火性能,利用高温燃烧炉对四面受火的试件高温下性能探究分析,将所得到的结果与钢筋混凝土柱子的计算承载力进行比较。使用薄钢管-防火涂料-CFRP共同加固完全破坏的钢筋混凝土柱子,得到了钢筋混凝土柱子的力学加固方法和抗火加固方法。得到结论:试件的耐火时间为3 h,证明这种加固方法不仅提高了试件常温的承载能力而且还使得试件具有优越的抗火性能。

关键词：防火涂料 CFRP 钢筋混凝土加固高温

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Nisin抗菌作用机制及抑菌效力

引用

食品科技 2004年第10期29卷 59-62页

作者：李增利江苏科技大学生化部镇江212004

Nisin是一种由乳酸乳球菌核糖体上合成的并经过一系列酶学修饰的以含有羊毛硫氨酸和β-甲基羊毛硫氨酸等稀有氨基酸为特征的抗菌肽,Nisin作用目标为细胞膜,Nisin与细胞膜通过结合,插入和孔道形成等多步过程形成孔道复合物,从而引起细胞... 详细信息

Nisin是一种由乳酸乳球菌核糖体上合成的并经过一系列酶学修饰的以含有羊毛硫氨酸和β-甲基羊毛硫氨酸等稀有氨基酸为特征的抗菌肽,Nisin作用目标为细胞膜,Nisin与细胞膜通过结合,插入和孔道形成等多步过程形成孔道复合物,从而引起细胞液渗漏。孔道的形成有“桶板”和“楔入”两种孔道模型。Nisin能够抑杀许多引起食品腐败的革兰阳性菌,Nisin的抑菌效率取决于其分子结构,受目标控制菌及其系统性质的影响,如Nisin抗性、膜干扰剂、亚致死伤害、阳离子、温度、pH、蛋白水解酶和其它防腐剂。

关键词： Nisin 抗菌机制孔道复合物 Lipid Ⅱ PMF Nisin抗性亚致死伤害抗菌效力

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：