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Ring-Shaped Jets in Gamma-Ray Bursts

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Chinese Journal of Astronomy and Astrophysics 2008年第4期8卷 411-420页

作者： ming Xu Yong-feng huang Si-Wei Kong Department of Astronomy Nanjing University Nanjing 210093 China

When the axis of a gamma-ray burst （GRB） does not coincide with the spin axis of its source, there may result a ring-shaped jet. Using some refined jet dynamics, we calculate multi-wavelength afterglow light curves for such ring-shaped jets. In the R-band we find an obvious break in the afterglow light curve due to the beaming effect and the break is affected by many parameters, such as the electron energy fraction ζe, the magnetic energy fraction ζB^2, the width of ring △θ and the medium number density n. The overall light curve can be divided into three power-law stages, i.e., an ultra-relativistic stage, an after-break stage and a deep Newtonian stage. For each stage the power-law index is larger in the ring-shaped jet than in the corresponding conical jet.

关键词： gamma rays bursts - ISM jets and outflows

Statistical extremes and peak factors in wind-induced vibration of tall buildings

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2012年第1期13卷 18-32页

作者： ming-feng huang Chun-man CHAN Wen-juan LOU Kenny Chung-Siu KWOK Institute of Structural Engineering Zhejiang University Hangzhou 310058 China Department of Civil and Environmental Engineering Hong Kong University of Science and Technology Hong Kong School of Engineering University of Western Sydney NSW Australia

In the structural design of tall buildings, peak factors have been widely used to predict mean extreme responses of tall buildings under wind excitations. Vanmarcke＇s peak factor is directly related to an explicit measure of structural reliability against a Gaussian response process. We review the use of this factor for time-variant reliability design by comparing it to the conven- tional Davenport＇s peak factor. Based on the asymptotic theory of statistical extremes, a new closed-form peak factor, the so-called Gamma peak factor, can be obtained for a non-Gaussian resultant response characterized by a Rayleigh distribution process. Using the Gamma peak factor, a combined peak factor method was developed for predicting the expected maximum resultant responses of a building undergoing lateral-torsional vibration. The effects of the standard deviation ratio of two sway components and the inter-component correlation on the evaluation of peak resultant response were also investigated. Utilizing wind tunnel data derived from synchronous multi-pressure measurements, we carried out a wind-induced time history response analysis of the Common- wealth Advisory Aeronautical Research Council （CAARC） standard tall building to validate the applicability of the Gamma peak factor to the prediction of the peak resultant acceleration. Results from the building example indicated that the use of the Gamma peak factor enables accurate predictions to be made of the mean extreme resultant acceleration responses for dynamic service- ability performance design of modem tall buildings.

关键词： Level-crossing rate (LCR) Wind-induced vibration Mean extreme response Combined resultant process Peakfactor method

Pretreatment neutrophil-to-lymphocyte and platelet-to- lymphocyte ratios do not predict survival in patients with cervical cancer treated with neoadjuvant chemotherapy and radical hysterectomy

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Chinese Medical Journal 2013年第8期126卷 1464-1468页

作者： WANG Dan WU ming feng feng-zhi huang Hui-fang YANG Jia-xin SHEN Keng XIANG Yang Department of Obstetrics and Gynecology Peking Union McdicalCotlege Hospital Peking Union Medical College and ChineseAcademy of Medical Sciences Beijing 100730 China

Background A few inflammatory markers were studied to evaluate their possible prognostic roles in various cancers. The neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio are hypothesized to reflect the systemic inflammation. The objective of the present study was to investigate whether or not the pretreatment neutrophil-to-lymphocyte ratio or platelet-to-lymphocyte ratio can predict the survival of patients with cervical cancer treated with neoadjuvant chemotherapy and radical hysterectomy. Methods We performed a retrospective study on cervical cancer patients （FIGO stage Ib2-11b） who had undergone neoadjuvant chemotherapy and radical hysterectomy at Peking Union Medical College Hospital between January 1999 and December 2010. Data on demographics, clinical prognostic markers and histopathology were collected and analyzed. Univariate and multivariate analyses for prognostic factors were performed. Results A total of 111 patients were identified. The median neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios were 2.4 and 142.2, respectively. Overall survival and progression-free survival were neither significantly different between patients with high and low neutrophil-to-lymphocyte ratio （P=0.149 and P=0.108） nor in high and low platelet-to-lymphocyte ratio （P=0.336 and P=0.510）. On multivariate analysis, lymph node status （P=O.O00 and P=-O.O07） and lymphovascular space involvement （P=0.001 and P=0.001） were independent prognostic factors of progression-free survival and overall survival. Conclusions Lymph node status and lymphovascular space involvement were found to be independent prognostic factors for patients with cervical cancer who underwent neoadjuvant chemotherapy and radical hysterectomy. The pretreatment neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios seemed not to predict the survival of patients with cervical cancer treated with neoadjuvant chemotherapy and radical hysterectomy.

关键词： cervical cancer, neoadjuvant chemotherapy radical hysterectomy neutrophil-to-lymphocvte ratio:plutclet-to-lymphcyte ratio

A High Power-Added-Efficiency 2.5-GHz Class-F Power Amplifier Using 0.5 μm GaN on SiC HEMT Technology

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Journal of Computer and Communications 2016年第3期4卷 74-78页

作者： Chia-Han Lin Hsien-Chin Chiu Min-Li Chou Hsiang-Chun Wang ming-feng huang Department of Electronic Engineering Chang Gung University No. 259 Wenhua 1st Rd. Guishan Dist. Taoyuan City 33302 Taiwan JMIC 16F. No.44 Sec. 2 Zhongshan N. Rd. Zhongshan Dist. Taipei City 104 Taiwan

This paper proposed the high-frequency, multi-harmonic-controlled, Class-F power amplifier (PA) implemented with 0.5 μm GaN Hetrojunction Electron Mobility Transistor (HEMT). For PA design at high frequencies, parasitics of a transistor significantly increase the difficulty of harmonic manipulation, compared to low-frequency cases. To overcome this issue, we propose a novel design methodology based on a band-reject, low-pass, output matching network, which is realized with passive components. This network provides optimal fundamental impedance and allows harmonic control up to the third order to enable an efficient Class-F behavior. The implemented PA exhibits performance at 2.5 GHz with a 50% PAE, 14 dB gain, and 10 W output power.

关键词： GaN High Power Class-F

Ru doping triggering reconstruction of cobalt phosphide for coupling glycerol electrooxidation with seawater electrolysis

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Journal of Energy Chemistry 2025年第1期100卷 317-326页

作者： Binglu Deng Jie Shen Jinxing Lu Chuqiang huang Zhuoyuan Chen feng Peng Yunpeng Liu School of Materials Science and Hydrogen Energy Foshan University School of Chemistry and Chemical Engineering Guangzhou University Guangdong Key Laboratory for Hydrogen Energy Technologies

Seawater electrolysis is a promising approach for sustainable energy without relying on precious ***,the large-scale seawater electrolysis is hindered by low catalytic efficiency and severe anode corrosion caused by the harmful *** contrast to the oxygen evolution reaction （OER）and chlorin ion oxidation reaction （ClOR）,glycerol oxidation reaction （GOR） is more thermodynamically and kinetically favorable ***,a Ru doping cobalt phosphide （Ru-CoP2） is proposed as a robust bifunctional electrocatalyst for seawater electrolysis and GOR,for the concurrent productions of hydrogen and value-added *** in situ and ex situ characterization analyses demonstrated that Ru doping featured in the dynamic reconstruction process from Ru-CoP2to Ru-CoOOH,accounting for the superior GOR *** coupling GOR with hydrogen evolution was realized by employing Ru-CoP2as both anode and cathode,requiring only a low voltage of 1.43 V at 100 mA cm-2,which was 250 m V lower than that in alkaline *** work guides the design of bifunctional electrocatalysts for energy-efficient seawater electrolysis coupled with biomass resource upcycling.

关键词： Anodes

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宽温低损耗单模光纤定向耦合器

光学学报 1989年第1期9卷 93-96页

作者：陆善达冯明和黄勇上海科学技术大学物理系

本文报道了用熔融法由常规的单模通信光纤制造宽温工作的低损耗单模光纤定向耦合器.工作波长为1.52μm,分束比为50%的封装器件;工作温度在-30～+70℃范围,分束比容差小于±5%,插入损耗40dB.工作波长的变化对分束比影响十分明显,但入射... 详细信息

本文报道了用熔融法由常规的单模通信光纤制造宽温工作的低损耗单模光纤定向耦合器.工作波长为1.52μm,分束比为50%的封装器件;工作温度在-30～+70℃范围,分束比容差小于±5%,插入损耗40dB.工作波长的变化对分束比影响十分明显,但入射光的偏振态对其无实际影响.

关键词：单模光纤定向耦合器熔融法

Meningeal lymphatic vessel crosstalk with central nervous system immune cells in aging and neurodegenerative diseases

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Neural Regeneration Research 2025年第3期20卷 763-778页

作者： minghuang Gao Xinyue Wang Shijie Su Weicheng feng Yaona Lai Kongli huang Dandan Cao Qi Wang Science and Technology Innovation Center Guangzhou University of Chinese MedicineGuangzhouGuangdong ProvinceChina Institute of Clinical Pharmacology Guangzhou University of Chinese MedicineGuangzhouGuangdong ProvinceChina The Sixth Affiliated Hospital Sun Yat-sen UniversityGuangzhouGuangdong ProvinceChina

Meningeal lymphatic vessels form a relationship between the nervous system and periphery, which is relevant in both health and disease. Meningeal lymphatic vessels not only play a key role in the drainage of brain metabolites but also contribute to antigen delivery and immune cell activation. The advent of novel genomic technologies has enabled rapid progress in the characterization of myeloid and lymphoid cells and their interactions with meningeal lymphatic vessels within the central nervous system. In this review, we provide an overview of the multifaceted roles of meningeal lymphatic vessels within the context of the central nervous system immune network, highlighting recent discoveries on the immunological niche provided by meningeal lymphatic vessels. Furthermore, we delve into the mechanisms of crosstalk between meningeal lymphatic vessels and immune cells in the central nervous system under both homeostatic conditions and neurodegenerative diseases, discussing how these interactions shape the pathological outcomes. Regulation of meningeal lymphatic vessel function and structure can influence lymphatic drainage, cerebrospinal fluid-borne immune modulators, and immune cell populations in aging and neurodegenerative disorders, thereby playing a key role in shaping meningeal and brain parenchyma immunity.

关键词： central nervous system meningeal lymphatic vessels immunity myeloid cells lymphatic cells neurodegenerative disease

微创可视化下技术在经皮胸腰椎椎体病变穿刺活检中的临床应用

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中国内镜杂志 2015年第11期21卷 1215-1219页

作者：黄保华陈远明周先明黄民锋广西中医药大学附属瑞康医院脊柱微创外科广西南宁530011

目的探讨椎间孔镜工作通道可视下穿刺活检在胸腰椎椎体病变的临床应用。方法对2012年12月-2014年4月在该院行病变穿刺活检病理检查的28例胸腰椎椎体病变患者资料进行分析。患者年龄19~78岁,平均56.4岁;男16例,女12例。术前均行脊柱X... 详细信息

目的探讨椎间孔镜工作通道可视下穿刺活检在胸腰椎椎体病变的临床应用。方法对2012年12月-2014年4月在该院行病变穿刺活检病理检查的28例胸腰椎椎体病变患者资料进行分析。患者年龄19~78岁,平均56.4岁;男16例,女12例。术前均行脊柱X线片、CT和MRI检查,为单椎体或者相邻椎间盘病变,提示椎体骨质不同程度破坏。其中,胸椎4例（T112例,L122例）,腰椎24例（L13例,L24例,L35例,L45例,L57例）,均在局麻下行C臂引导下辅助椎间孔镜成像系统穿刺活检术,工作通道下穿刺取出病变组织并病理检查。统计穿刺成功率,同时比较穿刺活检病理诊断与术后病理诊断的符合情况及并发症情况。结果穿刺活检病理诊断恶性肿瘤13例,良性肿瘤3例,炎性病变11例,正常组织1例,穿刺活检病理诊断阳性率为96.4%。26例患者行手术治疗,穿刺活检病理诊断与术后病理诊断一致,诊断符合率为92.3%;1例穿刺活检病理诊断为正常组织,术后病理诊断为非特异性炎症1例。1例穿刺活检病理诊断为炎性肉芽组织,术后病理诊断为骨的嗜酸性肉芽肿。胸11椎体活检术后患者出现肋间神经刺痛,随访未见肿瘤种植等并发症。结论微创可视化下穿刺活检术在胸腰椎椎体病变穿刺活检中能够在可视下取得较为充足的标本量,活检病理诊断阳性率及穿刺活检病理诊断与术后病理诊断符合率均较高,是一种诊断和治疗为一体的微创技术。

关键词：椎体穿刺活检微创

Overexpression of low-density lipoprotein receptor prevents neurotoxic polarization of astrocytes via inhibiting NLRP3 inflammasome activation in experimental ischemic stroke

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Neural Regeneration Research 2025年第2期20卷 491-502页

作者： Shuai feng Juanji Li Tingting Liu Shiqi huang Xiangliang Chen Shen Liu Junshan Zhou Hongdong Zhao Ye Hong Department of Neurology Nanjing First HospitalNanjing Medical UniversityNanjingJiangsu ProvinceChina Department of Neurology Nanjing Jinling HospitalAffiliated Hospital of Medical SchoolNanjing UniversityNanjingJiangsu ProvinceChina

Neurotoxic astrocytes are a promising therapeutic target for the attenuation of cerebral ischemia/reperfusion ***-density lipoprotein receptor,a classic cholesterol regulatory receptor,has been found to inhibit NLR family pyrin domain containing protein 3(NLRP3)inflammasome activation in neurons following ischemic stroke and to suppress the activation of microglia and astrocytes in individuals with Alzheimer’s ***,little is known about the effects of low-density lipoprotein receptor on astrocytic activation in ischemic *** address this issue in the present study,we examined the mechanisms by which low-density lipoprotein receptor regulates astrocytic polarization in ischemic stroke ***,we examined low-density lipoprotein receptor expression in astrocytes via immunofluorescence staining and western blotting *** observed significant downregulation of low-density lipoprotein receptor following middle cerebral artery occlusion reperfusion and oxygen-glucose deprivation/***,we induced the astrocyte-specific overexpression of low-density lipoprotein receptor using astrocyte-specific adeno-associated ***-density lipoprotein receptor overexpression in astrocytes improved neurological outcomes in middle cerebral artery occlusion mice and reversed neurotoxic astrocytes to create a neuroprotective ***,we found that the overexpression of low-density lipoprotein receptor inhibited NLRP3 inflammasome activation in oxygen-glucose deprivation/reoxygenation injured astrocytes and that the addition of nigericin,an NLRP3 agonist,restored the neurotoxic astrocyte *** findings suggest that low-density lipoprotein receptor could inhibit the NLRP3-meidiated neurotoxic polarization of astrocytes and that increasing low-density lipoprotein receptor in astrocytes might represent a novel strategy for treating cerebral ischemic stroke.

关键词： inflammation ischemia/reperfusion injury ischemic stroke low-density lipoprotein receptor neuroprotective astrocytes neurotoxic astrocytes NLRP3 inflammasome polarization