检索结果-南通市图书馆

Chinese Chemical Letters 2011年第2期22卷 197-200页

作者： Yan ming Liu Long fei peng Lin Mei Li Juan Liu College of Chemistry and Chemical Engineering Xinyang Normal University Xinyang 464000 China Received 1 July 2010

A new and simple capillary electrophoresis with electrochemiluminescence detection was developed for the separation and the quantification of a pair of diastereoisomenc alkaloids（ephedrine and pseudoephedrine）.The limits of detection（S/N = 3） were 4.5×10^-8 mol/L for ephedrine and 5.2×10^-8 mol/L for pseudoephedrine,*** RSDs of migration time and peak area were less than 1.3 and 2.5%（n = 5）,*** applicability of the propose method was illustrated in the determination of ephedrine and pseudoephedrine in human urine,ephedrine in nasal drops,and the monitoring of pharmacokinetics for pseudoephedrine.

关键词： CE Electrochemiluminescence Alkaloids Urine analysis Pharmacokinetics

Dynamic observation of bone marrow suppression and chromosomal aberrations in patients with acute colchicine poisoning

在线全文

学校读者我要写书评

暂无评论

World Journal of Emergency Medicine 2022年第2期13卷 130-134页

作者： Yan-qing Liu Xiao-xia Lu Kai-xun Hu Xiao-bo peng Yun Jiang Li-mei Han Zhi-qiang Ma ming-fei peng Kun Wan Xi-gang Zhang Ze-wu Qiu Poisoning Treatment Department Department of Hematologythe Fifth Medical Center of Chinese PLA General HospitalBeijing 100039China Academy of Military Medical Sciences Academy of Military SciencesBeijing 100850China

Colchicine is a neutral lipophilic tricyclic alkaloid toxic to human cells containing tubulin,[1-2]and primarily stops the proliferation of active cells in the mitotic metaphase,such as intestinal mucosal cells and hematopoietic *** is widely used in treating gout and familial Mediterranean fever,while it is also used in establishing animal and plant experimental model.[3]In the recent study,treatment of patients affected by coronavirus disease 2019(COVID-19)with colchicine may prove a viable path.[4]The course of colchicine poisoning can be divided into three stages,[5]and most of the patients died in the second stage(2-7 d,the multiple organ injury stage).The cause of death was heart failure[6]and bone marrow hematopoietic failure in the terminal phase.[7]Hematopoiesis is a classic sign of colchicine *** cases of colchicine poisoning have been comprehensively reported,and the target organs included heart,digestive tract,muscle,lung,kidney,hematopoietic system,etc.[8-11]This study aimed to investigate the injury of bone marrow hematopoietic system after colchicine poisoning and evaluate the therapeutic effect of bone marrow hematopoietic stimulation drugs.

关键词： establishing neutral alkaloid

Twelve family members with tetramine poisoning after consumption of vegetables grown in polluted soils

在线全文

学校读者我要写书评

暂无评论

World Journal of Emergency Medicine 2023年第3期14卷 250-252页

作者： Yan-qing Liu Xiao-xia Lu Chun-yan Wang ming-fei peng Xiao-bo peng Yun Jiang Le-xin Zheng Dan-dan Yuan Xi-gang Zhang Ze-wu Qiu Poisoning Treatment Department Senior Department of Hepatologythe Fifth Medical Center of PLA General HospitalBeijing 100071China

The main toxic component of tetramine is tetramethylenedisulfotetramine(TETS).It is a sulfonamide derivative without special antidote,tasteless and tasteless,with high toxicity and high mortality.[1]It was first discovered by a German scientist Hagen in *** its use has been banned worldwide due to its high toxicity and mortality rate,it is still available in certain countries and has led to cases of intentional and unintentional *** blocksγ-neurons,leading to dizziness,fatigue,nausea,vomiting,convulsions,and other symptoms.[2-4]Due to the lack of recognized effective antidotes,many poisoned people suff ocate and die as a result of continuous spasms of the respiratory muscles.[5-7]Tetramine poisoning sometimes occurs,but it is rare for vegetables grown in tetraminecontaminated soil to cause group poisoning after being eaten.

关键词： mortality poisoning vegetables

A Mn-porphyrinic metal–organic framework immobilizing glucose oxidase for combined photodynamic/chemodynamic/starvation therapy

在线全文

学校读者我要写书评

暂无评论

Tungsten 2025年第1期7卷 183-194页

作者： Xin-Ran Sun Hao-ming Yuan Guo-Da Zhang Chao Wang Shu-Juan Sun peng-fei Shi Shandong Provincial Key Laboratory of Detection Technology for Tumor Markers School of Chemistry and Chemical Engineering Linyi University

The combination of photodynamic therapy（PDT） and chemodynamic therapy（CDT） in tumor treatment has attracted considerable ***,tumor hypoxia and glutathione（GSH） overproduction in the tumor tissue restricted the progress of their ***,a Mn-porphyrinic metal-organic framework（Mn-TCPP） was constructed by the one-pot method and further used for immobilizing glucose oxidase（GOx） to obtain GOx@*** would rapidly exhaust endogenous glucose into hydrogen peroxide（H2O2） and gluconic acid,thus shutting off the energy supply of tumor cells for starvation ***-TCPP catalyzed H2O2to produce oxygen,regulating the hypoxic tumor microenvironment and in turn improving1O2generation under laser ***,Mn-TCPP can reduce reactive oxygen species consumption owing to the redox reaction between Mn3+and GSH,thus greatly enhancing ***,benefiting from GOx-mediated starvation therapy,Mn2+produced by Mn3+reduction can react with sufficient intracellular H2O2to generate ·OH with high cytotoxicity through a Fenton-like *** treatment by GOx@Mn-TCPP under laser irradiation in vitro,the cell viability of 4T1 and A549 tumor cells reached to 20%,reflecting GOx@Mn-TCPP could give full play to the advantages of PDT/CDT/starvation *** results in vivo demonstrated that GOx@Mn-TCPP mediated synergistic cascade therapy could significantly inhibit tumor growth and improve the therapeutic effect.

关键词： Chemodynamic therapy Immobilizing enzyme Metal–organic frameworks Photodynamic therapy Starvation therapy

Energy calculation of Fe(001) twist grain boundary

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

商丘师范学院学报 2009年第3期25卷 63-68页

作者： WANG Yong-ming WANG peng-fei College of Physics and Information Technology Shaanxi Normal University Xi＇an 710062 China

With modified analytical embedded atom method(MAEAM),the energy of(001)twist grain boundary(GB)has been calculated for metal *** results show that the unrelaxed energy keeps almost constant with twist angle θ except several cusps at some special Σ *** GB energies drop significantly after expansion perpendicular to the ***-boundary translation results in periodic energy variation,but the energy variation is slight.

关键词：物理教学铁原子 MAEAM GB

Activation of adult endogenous neurogenesis by a hyaluronic acid collagen gel containing basic fibroblast growth factor promotes remodeling and functional recovery of the injured cerebral cortex

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第10期20卷 2923-2937页

作者： Yan Li peng Hao Hongmei Duan fei Hao Wen Zhao Yudan Gao Zhaoyang Yang Kwok-Fai So Xiaoguang Li Department of Neurobiology School of Basic Medical SciencesCapital Medical UniversityBeijingChina China Rehabilitation Science Institute China Rehabilitation Research CenterBeijing Key Laboratory of Neural Injury and RehabilitationBeijingChina Center of Neural Injury and Repair Beijing Institute for Brain DisordersBeijingChina Beijing Key Laboratory for Biomaterials and Neural Regeneration School of Engineering MedicineBeihang UniversityBeijingChina Guangdong-HongKong-Macao Institute of CNS Regeneration Ministry of Education CNS Regeneration Collaborative Joint LaboratoryJinan UniversityGuangzhouGuangdong ProvinceChina Bioland Laboratory(Guangzhou Regenerative Medicine and Health Guangdong Laboratory) GuangzhouGuangdong ProvinceChina Department of Ophthalmology and State Key Laboratory of Brain and Cognitive Sciences The University of Hong KongHong Kong Special Administration RegionChina Center for Brain Science and Brain-Inspired Intelligence Guangdong-HongKong-Macao Greater Bay AreaGuangzhouGuangdong ProvinceChina Co-innovation Center of Neuroregeneration Nantong UniversityNantongJiangsu ProvinceChina Department of Biomedical Engineering School of Biological Science and Medical EngineeringBeihang UniversityBeijingChina

The presence of endogenous neural stem/progenitor cells in the adult mammalian brain suggests that the central nervous system can be repaired and regenerated after ***,whether it is possible to stimulate neurogenesis and reconstruct cortical layers II to VI in non-neurogenic regions,such as the cortex,remains *** this study,we implanted a hyaluronic acid collagen gel loaded with basic fibroblast growth factor into the motor cortex immediately following traumatic *** findings reveal that this gel effectively stimulated the proliferation and migration of endogenous neural stem/progenitor cells,as well as their differentiation into mature and functionally integrated ***,these new neurons reconstructed the architecture of cortical layers II to VI,integrated into the existing neural circuitry,and ultimately led to improved brain *** findings offer novel insight into potential clinical treatments for traumatic cerebral cortex injuries.

关键词： adult endogenous neurogenesis basic fibroblast growth factor-hyaluronic acid collagen gel cortical remodeling functional recovery migration motor cortex injury neural circuits neural stem cells newborn neurons proliferation

Crystallization Modulation and Holistic Passivation Enables Efficient Two‑Terminal Perovskite/CuIn(Ga)Se_(2)Tandem Solar Cells

在线全文

学校读者我要写书评

暂无评论

Nano-Micro Letters 2025年第1期17卷 205-215页

作者： Cong Geng Kuanxiang Zhang Changhua Wang Chung Hsien Wu Jiwen Jiang fei Long Liyuan Han Qifeng Han Yi‑Bing Cheng Yong peng State Key Laboratory of Advanced Technology for Materials Synthesis and Processing Wuhan University of TechnologyWuhan 430070People’s Republic of China Triumph Photovoltaic Materials Co. Ltd.No.1001 Yannan AvenueHigh‑Tech Development DistrictBengbuAnhui 233000People’s Republic of China College of Materials Science and Engineering Guilin University of TechnologyGuilin 541004People’s Republic of China State Key Laboratory of Metal Matrix Composites Shanghai Jiao Tong UniversityShanghai 200240People’s Republic of China

Two-terminal(2-T)perovskite(PVK)/CuIn(Ga)Se_(2)(CIGS)tandem solar cells(TSCs)have been considered as an ideal tandem cell because of their best bandgap matching regarding to Shockley–Queisser(S–Q)***,the nature of the irregular rough morphology of commercial CIGS prevents people from improving tandem device *** this paper,D-homoserine lactone hydrochloride is proven to improve coverage of PVK materials on irregular rough CIGS surfaces and also passivate bulk defects by modulating the growth of PVK *** addition,the minority carriers near the PVK/C60 interface and the incompletely passivated trap states caused interface recombination.A surface reconstruction with 2-thiopheneethylammonium iodide and N,N-dimethylformamide assisted passivates the defect sites located at the surface and grain ***,LiF is used to create this field effect,repelling hole carriers away from the PVK and C60 interface and thus reducing *** a result,a 2-T PVK/CIGS tandem yielded a power conversion efficiency of 24.6%(0.16 cm^(2)),one of the highest results for 2-T PVK/CIGS TSCs to our *** validation underscores the potential of our methodology in achieving superior performance in PVK/CIGS tandem solar cells.

关键词： PVK/CIGS TSCs Irregular rough surfaces Modulating the growth PVK/C60 interface recombination

在线全文

学校读者我要写书评

暂无评论

巷道腰线标定新方法探讨

煤炭与化工 2014年第5期37卷 132-134页

作者：明鹏飞山西兰花百盛煤业有限公司山西高平048400

针对传统巷道腰线标定方法中存在精度不高等问题,通过工程实践,总结分析出使用免棱镜全站仪来标定巷道腰线的新方法,使得在巷道腰线标定方面更加方便、快捷、精度更高,为类似情况提供经验借鉴。

关键词：免棱镜全站仪巷道腰线标定新方法

在线全文

学校读者我要写书评

暂无评论

起重机吊钩防脱钩装置的改进

起重运输机械 2009年第9期 106-107页

作者：明鹏飞丹东市锅炉压力容器检验研究所

按照起重机使用规范,起重机吊钩上必须设置防脱钩装置。但从事检验过程中,经常发现起重设备的吊钩缺少防脱钩装置,有的严重变形,有的回位弹簧损坏,失去防脱作用。这样,在生产中留下了安全隐患,而且已经出现了多起吊索脱钩造成重物坠落... 详细信息

按照起重机使用规范,起重机吊钩上必须设置防脱钩装置。但从事检验过程中,经常发现起重设备的吊钩缺少防脱钩装置,有的严重变形,有的回位弹簧损坏,失去防脱作用。这样,在生产中留下了安全隐患,而且已经出现了多起吊索脱钩造成重物坠落、人员伤亡的事故。

关键词：脱钩装置起重机吊钩使用规范检验过程起重设备弹簧损坏安全隐患

不同饲料对银鲳幼鱼增重率、肝脏脂酶及抗氧化酶活性的影响

在线全文

学校读者我要写书评

暂无评论

水产学报 2010年第6期34卷 949-954页

作者：彭士明尹飞孙鹏施兆鸿王建钢中国水产科学研究院东海水产研究所

利用营养学与生物化学的方法,研究分析了不同饲料对银鲳幼鱼增重率、饲料系数、肝脏脂酶及抗氧化酶活性的影响。试验共设4组不同饲料,依次为饲料1(新鲜鱼肉糜)、饲料2(新鲜鱼肉糜+饲料)、饲料3(新鲜鱼肉糜+饲料+蛏子肉糜)和饲料4(新鲜... 详细信息

利用营养学与生物化学的方法,研究分析了不同饲料对银鲳幼鱼增重率、饲料系数、肝脏脂酶及抗氧化酶活性的影响。试验共设4组不同饲料,依次为饲料1(新鲜鱼肉糜)、饲料2(新鲜鱼肉糜+饲料)、饲料3(新鲜鱼肉糜+饲料+蛏子肉糜)和饲料4(新鲜鱼肉糜+饲料+蛏子肉糜+桡足类)。试验用银鲳幼鱼的平均体重为(4.80±0.11)g,每组饲料设3重复,试验周期为9周。研究结果显示,不同饲料可显著影响银鲳的增重率,各饲料组中以饲料1组的增重率最低,并显著低于其它各饲料组;饲料4组的增重率最高,并显著高于饲料2、3组的增重率(P0.05)。饲料1组肝脂酶与总脂酶活性均显著低于其它3组饲料组(P0.05)。各组间肝脏超氧化物歧化酶(SOD)与谷胱甘肽过氧化物酶(GSH-PX)活性均未有显著性差异(P>0.05),但均以饲料1组最低、饲料4组最高;饲料1、2、3组间肝脏过氧化氢酶(CAT)活性未有显著性差异(P>0.05),但饲料4组CAT活性显著高于饲料1组的CAT活性(P<0.05)。分析结果表明,单纯利用鱼肉糜作为饲料不利于银鲳的生长;饲料中添加桡足类不但有助于促进银鲳的生长,也可提高其抗氧化能力。

关键词：银鲳饲料生长脂酶抗氧化酶