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A guidance and control design with reduced information for a dual-spin stabilized projectile

Defence Technology（防务技术） 2024年第3期33卷 494-505页

作者： Yu Wang Jiyan Yu Xiaoming Wang jia Fangxiu Intelligent Ammunition Technology National Defense Key Discipline Laboratory Nanjing University of Science and TechnologyNanjingJiangsu210094China

In this paper,an integrated guidance and control method based on an adaptive path-following controller is proposed to control a spin-stabilized projectile with only translational motion information under the constraint of an actuator,uncertainties in aerodynamic parameters and measurements,and control system *** to the fairly high rotation speed,the dynamic model of this missile is strongly nonlinear,uncertain and coupled in pitch,yaw and roll channels.A theoretical equivalent resultant force and uncertainty compensation method are comprehensively used to realize decoupling of pitch and *** response to the strong nonlinear and time-varying characteristics of the dynamic system,the quasi-linear model whose parameters are obtained by interpolation of points selected as the segmentation points in the trajectory envelope,is used for calculation in each *** cope with the system uncertainty caused by model approximation,parameter uncertainty and ballistic interference,an extended state estimator is used to compensate the output feedback according to the test ballistic *** order to improve the tracking efficiency and ensure the tracking error convergence with only translational motion information,the virtual guide point,whose derivative is deduced according to the Lyapunov principle,is calculated in real time according to the projection relationship between the real-time position and the reference trajectory,and a virtual line-of-sight angle and the backstepping method are used for the design of the guidance and control *** order to avoid the influence of control input saturation on the guidance and control performance due to the actuator limitation and improve the robustness of the system,an anti-saturation compensator is designed according to the two-step *** feasibility and effectiveness of the path-following controller is verified through closed-loop flight simulations with measurement,control,and condition *** result

关键词： Spin-stabilized projectile Reduced information Path-following control Extended state observer Coupled nonlinear system Input saturation

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Design of acceleration control schedule for adaptive cycle engine based on direct simulation model

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Chinese Journal of Aeronautics 2024年第6期37卷 307-318页

作者： Keran SONG Linyuan jia Yuchun CHEN Tian TAN School of Power and Energy Northwestern Polytechnical UniversityXi’an 710072China

To design the optimum acceleration control schedule for the Adaptive Cycle Engine(ACE)in the full flight envelope,this paper establishes a direct simulation model of the ACE transient *** this model,geometric parameters are used to replace the component state *** corresponding relationship between geometric parameters and component state parameters is determined by sensitivity *** geometric variables are controlled when the geometric adjustment speed exceeds the limit,and at the same time the corresponding component state parameters are *** gradient optimization algorism is used to optimize the ground acceleration process of ACE,and the control schedule in terms of operating point of compression components and corrected acceleration rate is used as the full-envelope acceleration control schedule based on the similarity *** acceleration control schedules of the triple-bypass mode and the double-bypass mode are designed in this *** acceleration processes under various flight conditions are simulated using the acceleration control *** with the acceleration process with the linear geometric adjustment schedule,the acceleration performance of ACE is improved by the acceleration control schedule,with the impulse of the acceleration process of the triple-bypass mode being increased by 8.7%-12.3% and the impulse of the double-bypass mode acceleration process being increased by 11.8%-14.1%.

关键词： Adaptive Cycle Engine(ACE) Direct simulation method Acceleration Control schedule Full flight envelope

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Nuclear transport receptors underpin plastidial retrograde signaling

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Molecular Plant 2024年第7期17卷 993-995页

作者： Min jia Yangnan Gu Department of Plant and Microbial Biology University of CaliforniaBerkeleyBerkeleyCAUSA

The nucleus integrates cytosolic and organellar signals to regulate gene expression during plant stress responses,and this process is highly dependent on shuttling of signaling molecules in and out of the *** nucleocytoplasmic transport of macromolecules is facilitated by nuclear transport receptors(NTRs).NTRs are broadly categorized into exportins,which mediate the export of cargo from the nucleus to the cytoplasm,and importins,which facilitate the import of cargo into the *** importin family comprises importin-α(IMPa)and importin-β(IMPp).IMPa proteins are adaptor proteins and composed of three functional domains:an N-terminal IMPβ-binding(IBB)domain,ten Armadillo(ARM)repeats responsible for recognizing and interacting with cargo,and an exportin-interacting domain crucial for recycling via nuclear export(Wing et al.,2022).During a nuclear transport event,*** cargo containing a classical nuclear localization signal(cNLS)through its ARM repeats and engages IMPβvia its IBB domain,forming the cargo-IMPa-IMPβternary ***βfacilitates translocation of this complex through the nuclear *** inside the nucleus,RanGTP competes with IMPa for binding to IMPβ,promoting disassembly of the transport complex and releaseofcargo.

关键词： complex. integrate ternary

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Activation of LONP1 by 84-B10 alleviates aristolochic acid nephropathy via re-establishing mitochondrial and peroxisomal homeostasis

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Chinese Journal of Natural Medicines 2024年第9期22卷 808-821页

作者： XU Xinyue ZHU Wenping miao Mengqiu BAI Mi FAN jiaojiao NIU Yujia LI Yuting ZHANG Aihua jia Zhanjun WU Mengqiu School of Medicine Southeast UniversityNanjing 210009China Department of Nephrology Children’s Hospital of Nanjing Medical UniversityNanjing 210008China Nanjing Key Laboratory of Pediatrics Children’s Hospital of Nanjing Medical UniversityNanjing 210008China jiangsu Key Laboratory of Early Development and Chronic Diseases Prevention in Children Nanjing Medical UniversityNanjing 210029China

Pharmaceutical formulations derived from Aristolochiaceae herbs, which contain aristolochic acids(AAs), are widely used for medicinal purposes. However, exposure to these plants and isolated AAs is linked to renal toxicity, known as AA nephropathy(AAN). Currently, the mechanisms underlying AAN are not fully understood, leading to unsatisfactory treatment strategies. In this study, we explored the protective role of 84-B10(5-[[2-(4-methoxyphenoxy)-5-(trifluoromethyl) phenyl] amino]-5-oxo-3-phenylpentanoic acid) against AAN. RNA-seq analysis revealed that the mitochondrion and peroxisome were the most affected cellular components following 84-B10 treatment in AAN mice. Consistently, 84-B10 treatment preserved mitochondrial ultrastructure, restored mitochondrial respiration, enhanced the expression of key transporters(carnitine palmitoyltransferase 2) and enzymes(acylCoenzyme A dehydrogenase, medium chain) involved in mitochondrial fatty acid β-oxidation, and reduced mitochondrial ROS generation in both aristolochic acid I(AAI)-challenged mice kidneys and cultured proximal tubular epithelial cells. Additionally, 84-B10 treatment increased the expression of key transporters(ATP binding cassette subfamily D) and rate-limiting enzymes(acyl-CoA oxidase 1) involved in peroxisomal fatty acid β-oxidation and restored peroxisomal redox balance. Knocking down LONP1 expression diminished the protective effects of 84-B10 against AAN, suggesting LONP1-dependent protection. In conclusion, our study provides evidence that AAN is associated with significant disturbances in both mitochondrial and peroxisomal functions. The LONP1 activator 84-B10 demonstrates therapeutic potential against AAN, likely by maintaining homeostasis in both mitochondria and peroxisomes.

关键词： Aristolochic acid nephropathy 84-B10 LONP1 Mitochondrion Peroxisome

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Optimization of the co-closing law of guide vanes and blades for bulb turbines based on CFD

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Journal of Hydrodynamics 2024年第2期36卷 363-377页

作者： Hui Liu Yun-fa Lin Yong-guang Cheng Song Xue Mao-jia Tang jian Zhang jia-yi Fan State Key Laboratory of Water Resources Engineering and Management Wuhan UniversityWuhan430072China Dongfang Electric Machinery Co. Ltd.Deyang618000China

The load rejection transient process of bulb turbine units is critical to safety of hydropower stations,and determining appropriate closing laws of guide vanes(GVs)and runner blades(RBs)for this process is of *** this study,we proposed a procedure to optimize the co-closing law of GVs and RBs by using computational fluid dynamics(CFD),combined with the design of experiment(DOE)method,approximation model,and genetic optimization *** sensitivity of closing law parameters on the histories of head,speed,and thrust was analyzed,and a two-stage GVs’closing law associating with a linear RBs’closing law was *** results show that GVs dominate the transient characteristics by controlling the change of *** GVs’first-stage closing speed while shortening first-stage closing time can not only significantly reduce the maximum rotational speed but also suppress the water hammer pressure;slowing GVs’second-stage closing speed is conducive to controlling the maximum reverse axial *** directly affect the runner *** RBs’closing speed can further reduce the rotational speed and the maximum reverse axial *** safety margin of each control parameter,flow patterns,and pressure pulsations of a practical hydropower station were all improved after optimization,demonstrating the effectiveness of this method.

关键词： Bulb turbine load rejection transient process double regulation closing law optimization computational fluid dynamics(CFD)

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Glutamate oxidase-integrated biomimetic Fe_(3)O_(4) hybrids as cascade nanozymes for glutamate detection

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Particuology 2024年第5期88卷 192-200页

作者： Peikun Li Yanchao Wang Xiuyan Luo Zixin Geng jiahui jia Ruirui Wang jiandong Cui Hongjie Bian Shiru jia State Key Laboratory of Food Nutrition and Safety Laboratory of Industrial Fermentation MicrobiologyMinistry of EducationTianjin University of Science and TechnologyTianjin300457China Sports Department Hebei University of Science and TechnologyShijiazhang050000China Research Center for Fermentation Engineering of Hebei College of Bioscience and BioengineeringHebei University of Science and TechnologyShijiazhang050000China

Herein,a new nanozyme/natural enzyme hybrid biosensor was established for ultrasensitive l-glutamic acid(L-Glu)*** Fe_(3)O_(4) nanoparticles with peroxidase-like activity and stability was used as a nanozyme and carrier for immobilizing l-Glutamate oxidase(GLOD)through Schiffff base reaction to construct a chem-enzyme cascade *** resultant Fe_(3)O_(4)-GOLD exhibited a wide linear range(10−500μM)and a low detection limit of 6.03μM for L-Glu ***,the Fe_(3)O_(4)-GOLD exhibited excellent pH stability,thermal stability,reusability and storage *** repeated nine cycles,Fe_(3)O_(4)-GOLD still retained 70%of its initial ***,Fe_(3)O_(4)-GOLD maintained 50%of its initial activity after storage for 20 days,while free GLOD only retained 20%of its initial *** strategy of integrating biomimetic Fe 3 O4 and natural enzymes for cascade catalysis makes it possible to design an efficient and stable chemo-enzyme composite catalysts,which are promising for applications in biosensing and biomimetic catalysis.

关键词： Fe_(3)O_(4) nanozyme GLOD Chemo-enzymes Glutamate detection

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A robust implicit high-order discontinuous Galerkin method for solving compressible Navier-Stokes equations on arbitrary grids

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Acta Mechanica Sinica 2024年第8期40卷 96-119页

作者： jia Yan Xiaoquan Yang Peifen Weng Shanghai Institute of Applied Mathematics and Mechanics Shanghai Key Laboratory of Mechanics in Energy EngineeringSchool of Mechanics and Engineering ScienceShanghai UniversityShanghai200072China College of Energy and Mechanical Engineering Shanghai University of Electric PowerShanghai200090China

The primary impediments impeding the implementation of high-order methods in simulating viscous flow over complex configurations are robustness and *** challenges impose significant constraints on computational efficiency,particularly in the domain of engineering *** address these concerns,this paper proposes a robust implicit high-order discontinuous Galerkin(DG)method for solving compressible Navier-Stokes(NS)equations on arbitrary *** method achieves a favorable equilibrium between computational stability and *** solve the linear system,an exact Jacobian matrix solving strategy is employed for preconditioning and matrix-vector generation in the generalized minimal residual(GMRES)*** approach mitigates numerical errors in Jacobian solution during implicit calculations and facilitates the implementation of an adaptive Courant-Friedrichs-Lewy(CFL)number increasing strategy,with the aim of improving convergence and *** further enhance the applicability of the proposed method for intricate grid distortions,all simulations are performed in the reference *** practice significantly improves the reversibility of the mass matrix in implicit calculations.A comprehensive analysis of various parameters influencing computational stability and efficiency is conducted,including CFL number,Krylov subspace size,and GMRES convergence *** computed results from a series of numerical test cases demonstrate the promising results achieved by combining the DG method,GMRES solver,exact Jacobian matrix,adaptive CFL number,and reference domain calculations in terms of robustness,convergence,and *** analysis results can serve as a reference for implicit computation in high-order calculations.

关键词： Discontinuous Galerkin method Exact Jacobian matrix GMRES solver Adaptive CFL number Reference domain High-order

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Optimal V_(2)O_(3) extraction by sustainable vanadate electrolysis in molten salts

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Tungsten 2024年第1期6卷 141-149页

作者： Bao-Yan Feng Zhong-Hua Zhao Yong-Zheng jia jia-Liang An Ming-Yong Wang State Key Laboratory of Advanced Metallurgy University of Science and Technology BeijingBeijing 100083China Beijing Key Laboratory of Green Recovery and Extraction of Rare and Precious Metals University of Science and Technology BeijingBeijing 100083China

Recently,an environmentally friendly electrolysis process of soluble vanadates is proposed and successfully confirmed for V_(2)O_(3) *** this paper,the solubilities of various vanadates(***_(3),Na_(4)V_(2)O_(7) and Na_(3)VO_(4))in NaCl molten salt are *** dependences of V_(2)O_(3) extraction on vanadate form,anode material and molten salt system are studied.A long-term electrolysis is carried *** result indicates that the solubilities of all vanadates are high and meet electrolytic *** to Na_(4)V_(2)O_(7) and Na_(3)VO_(4),NaVO_(3) exhibits larger current efficiency and lower electricity *** using SnO_(2) anode instead of graphite anode,the current efficiency of NaVO_(3) electrolysis can be increased to 58.1%and carbon pollution is avoided at 700℃.The extraction rate of V_(2)O_(3) reaches 81.3%after long-term electrolysis of 51 *** work optimizes the electrochemical preparation process of V_(2)O_(3) from various vanadates and contributes to the improvement of current efficiency and extraction rate.

关键词： Molten salt electrolysis Vanadate Vanadium trioxide Current efficiency

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Periapsis shift in spherically symmetric spacetimes and effects of electric interactions

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Chinese Physics C 2024年第8期48卷 224-239页

作者： Qianchuan Wang Junji jia School of Physics and Technology Wuhan UniversityWuhan 430072China Department of Astronomy&MOE Key Laboratory of Artificial Micro-and Nano-structures School of Physics and TechnologyWuhan UniversityWuhan 430072China

The periapsis shift of charged test particles in arbitrary static and spherically symmetric charged spacetimes are *** perturbative methods,the near-circular approximation and post-Newtonian methods,are developed and shown to be very accurate when the results are determined to high *** near-circular approximation method is more precise when eccentricity e of the orbit is small,whereas the post-Newtonian method is more effective when orbit semilatus rectum p is *** from these two methods are shown to agree when both e is small and p is *** results are then applied to the Reissner-Nordström spacetime,the Einstein-Maxwell-dilation gravity,and a charged wormhole *** effects of various parameters on the periapsis shift,particularly that of the electrostatic interaction,are carefully *** periapsis shift data of the solar-Mercury are then used to constrain the charges of the Sun and Mercury,and the data of the Sgr A^(*)-S2 periapsis shift are used to determine,for the first time using this method,the constraints of the charges of Sgr A^(*)and S2.

关键词： periapsis shift orbital precession post-Newtonian approximation perturbative method

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Sulfated peptides and their receptors:Key regulators of plant development and stress adaptation

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Plant Communications 2024年第6期5卷 44-56页

作者： Liming He Liangfan Wu jia Li Ministry of Education Key Laboratory of Cell Activities and Stress Adaptations School of Life SciencesLanzhou UniversityLanzhou 730000China Guangdong Provincial Key Laboratory of Plant Adaptation and Molecular Design School of Life SciencesGuangzhou UniversityGuangzhou 510006China

Four distinct types of sulfated peptides have been identiﬁed in Arabidopsis *** peptides play crucial roles in regulating plant development and stress *** studies have revealed that Xan-thomonas and Meloidogyne can secrete plant-like sulfated peptides,exploiting the plant sulfated peptide signaling pathway to suppress plant *** the past three decades,receptors for these four types of sulfated peptides have been identiﬁed,all of which belong to the leucine-rich repeat receptor-like protein kinase subfamily.A number of regulatory proteins have been demonstrated to play important roles in their corresponding signal transduction *** this review,we comprehensively summarize the discov-eries of sulfated peptides and their receptors,mainly in Arabidopsis *** also discuss their known biological functions in plant development and stress ***,we put forward a number of ques-tions for reference in future studies.

关键词： peptide hormone sulfated peptide receptor-like protein kinase plant development stress adaptation

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