检索结果-南通市图书馆

Surgical interventions for anterior shoulder instability in rugby players: A systematic review

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Orthopedics 2015年第4期6卷 400-408页

作者： Sanjeeve Sabharwal Nirav K Patel Anthony mj Bull Peter Reilly SpR Trauma and Orthopaedics Imperial College NHS Trust St Mary’s Hospital Musculoskeletal Mechanics Imperial College London Imperial College London Imperial College NHS Trust St Mary’s Hospital

AIM: To systematically evaluate the evidence-based literature on surgical treatment interventions for elite rugby players with anterior shoulder instability. METHODS: We conducted a systematic review according to the PRISMA guidelines. A literature search was performed in PubM ed, EMBASE and Google Scholar using the following search terms: "rugby" and "shoulder" in combination with "instability" or "dislocation". All articles published from inception of the included data sources to January 1st 2014 that evaluated surgical treatment of elite rugby players with anterior shoulder instability were examined. RESULTS: Only five studies were found that met the eligibility criteria. A total of 379 shoulders in 376 elite rugby union and league players were included. All the studies were retrospective cohort or case series studies. The mean Coleman Methodological Score for the 5 studies was 47.4(poor). Owing to heterogeneity amongst the studies, quantitative synthesis was not possible, however a detailed qualitative synthesis is reported. The overall recurrence rate of instability after surgery was 8.7%, and the mean return to competitive play, where reported, was 13 ***: Arthroscopic stabilization has been performed successfully in acute anterior instability and there is a preference for open Latarjet-type procedures when instability is associated with osseous defects.

关键词： Shoulder Instability Dislocation Rugby Latarjet

Single-nucleotide polymorphisms of matrix metalloproteinases and their inhibitors in gastrointestinal cancer

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastrointestinal Oncology 2011年第6期3卷 79-98页

作者： Alexandra mj Langers Hein W Verspaget Daniel W Hommes Cornelis FM Sier Department of Gastroenterology andHepatology Leiden University Medical CenterPO Box 96002300 RC LeidenThe Netherlands

Matrix metalloproteinases(MMPs) are implicated in cancer development and progression and are associated with ***-nucleotide polymorphisms(SNPs) of MMPs,most frequently located in the promoter region of the genes,have been shown to influence cancer susceptibility and/or *** of MMP-1,-2,-3,-7,-8,-9,-12,-13 and-21 and of the tissue inhibitor of metalloproteinases(TIMPs) TIMP-1 and TIMP-2 have been studied in digestive tract *** contribution of these polymorphisms to the cancer risk and prognosis of gastrointestinal tumors are reviewed in this paper.

关键词： Matrix metalloproteinase Tissue inhibitor of metalloproteinase Single nucleotide polymorphism Promoter region Digestive tract Cancer

Low rates of adherence for tumor necrosis factor-α inhibitors in Crohn's disease and rheumatoid arthritis: Results of a systematic review

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2013年第27期19卷 4344-4350页

作者： Herma H Fidder Maartje mj Singendonk Mike van der Have Bas Oldenburg Martijn GH van Oijen Department of Gastroenterology and Hepatology University Medical Center Utrecht

AIM:To investigate adherence rates in tumor necrosis factor-α (TNF-α)-inhibitors in Crohn's disease (CD) and rheumatoid arthritis (RA) by systematic review of medical literature. METHODS:A structured search of PubMed between 2001 and 2011 was conducted to identify publications that assessed treatment with TNF-α inhibitors providing data about adherence in CD and RA. Therapeutic agents of interest where adalimumab, infliximab and etanercept, since these are most commonly used for both diseases. Studies assessing only drug survival or continuation rates were excluded. Data describing adherence with TNF-α inhibitors were extracted for each selected study. Given the large variation between definitions of measurement of adherence, the definitions as used by the authors where used in our calculations. Data were tabulated and also presented descriptively. Sample size-weighted pooled proportions of patients adherent to therapy and their 95%CI were *** compare adherence between infliximab, adalimumab and etanercept, the adherence rates where graphed alongside two axes. Possible determinants of adherence were extracted from the selected studies and tabulated using the presented OR. RESULTS:Three studies on CD and three on RA were identified, involving a total of 8147 patients (953 CD and 7194 RA). We identified considerable variation in the definitions and methodologies of measuring adherence between studies. The calculated overall sample size-weighted pooled proportion for adherence to TNF-α inhibitors in CD was 70% (95%CI:67%-73%) and 59% in RA (95%CI:58%-60%). In CD the adherence rate for infliximab (72%) was highercompared to adalimumab (55%), with a relative risk of 1.61 (95%CI:1.27-2.03), whereas in RA adherence for adalimumab (67%) was higher compared to both infliximab (48%) and etanercept (59%), with a relative risk of 1.41 (95%CI:1.3-1.52) and 1.13 (95%CI:1.10-1.18) respectively. In comparative studies in RA adherence to infliximab was better than etanerce

关键词： Adherence Tumor necrosis factor-α inhibitors Systematic review Crohn’s disease Rheumatoid arthritis

Auto immune hepatitis

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2016年第19期22卷 4651-4661页

作者： nicole mf van gerven ynto s de boer chris jj mulder carin mj van nieuwkerk gerd bouma department of gastroenterology and hepatology vu university medical centre1081 HV Amsterdam The Netherlands

To provide an update of the latest trends in epidemiology, clinical course, diagnostics, complications and treatment of auto immune hepatitis(AIH). A search ofthe MEDLINE database was performed using the search terms: "auto immune hepatitis", "clinical presentation", "symptoms", "signs", "diagnosis", "auto antibodies", "laboratory values", "serology", "histopathology", " h i s t o l o g y ", " g e n e t i c s ", "HLA g e n e s ", "non-HLA genes", "environment", "epidemiology", "prevalence", "incidence", "demographics", "complications", "HCC", "PBC", "PSC", "corticosteroid", "therapy", "treatment", "alternative treatment". English-language full-text articles and abstracts were considered. Articles included reviews, meta-analysis, prospective retrospective studies. No publication date restrictions were applied. AIH is an immune meditated progressive inflammatory liver disease that predominantly affects middle-aged females but may affect people of all ages. The clinical spectrum of AIH is wide, ranging from absent or mild symptoms to fulminant hepatic failure. The aetiology of AIH is still unknown, but is believed to occur as the consequence of an aberrant immune response towards an un-known trigger in a genetically susceptible host. In the absence of a gold standard, diagnosis is based on the combination of clinical, biochemical and histopathological criteria. Immunosuppressive treatment has been the cornerstone of treatment since the earliest description of the disease in 1950 by Waldenstr?m. Such treatment is often successful at inducing remission and generally leads to normal life expectancy. Nevertheless, there remain significant areas of unmet aetiological a clinical needs including fundamental insight in disease pathogenesis, optimal therapy, duration of treatment and treatment alternatives in those patients unresponsive to standard treatment regimens.

关键词： Auto immune hepatitis Diagnosis Liver Epidemiology Treatment

SYNTHESIS　OF　FULLERENE　PYRROLIDINES　CONTAINING　SUBSTITUTED　PHENYL　GROUPS　THROUGH　AZOMETHINE　YLIDE　ADDITION

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Chemical Letters 1995年第12期6卷 1033-1036页

作者： Zhou, DJ Gan, LB Tan, HS Luo, CP Huang, CH Pan, JQ Lu, mj Wu, Y Beijing Univ State Key Lab Rare Earth Mat Chem & Applicat Beijing 100871 Peoples R China Beijing Univ Dept Chem Ctr Anal & Measurement Beijing 100871 Peoples R China Beijing Inst Microchem Beijing 100091 Peoples R China

Terephthalaldehyde reacts with sarcosine to form azomethine ylide, which adds to C60 according to a[3+2] cycloaddition process to form fullerene pyrrolidine. The same addition reaction can also be applied to other sub...

关键词：

The origins of catalytic activity in nucleolytic ribozymes

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

The origins of catalytic activity in nucleolytic ribozymes

第六届全国化学生物学学术会议

作者： David mj Lilley University of Dundee United Kingdom

＜正＞Ribozymes are enzymes that are made of RNA rather than *** nucleolytic ribozymes catalyse site-specific phosphodiester cleavage and ligation transesterification reactions in *** achieve impressive feats of catalysis,and yet have a fraction of the chemical functionality that proteins can bring to bear on their substrates.

关键词：

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

拜新同INSIGHT试验

临床心血管病杂志 2000年第8期16卷 I002-I003页

作者： Rrown,mj Palmer,C

Nearest Object Priority Based Integrated Rough Surface Scattering Algorithm for 3D Indoor Propagation Prediction

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

China Communications 2014年第10期11卷 147-158页

作者： ASMZ Kausar AW Reza KA Noordin mj Islam H Ramiah Department of Electrical Engineering Faculty of Engineering University of Malaya Kuala Lumpur 50603 Malaysia

Since rough surface scattering has a great impact on the accuracy of the propagation prediction algorithm,an integrated algorithm for indoor propagation prediction including rough surface scattering is proposed *** algorithm is composed of a three dimensional(3D) ray tracing algorithm based on binary space partitioning(BSP) and a diffuse scattering algorithm based on Oren-Nayar's *** of accuracy and prohibitive time consumption are the main drawbacks of the existing ray tracing based propagation prediction *** defy these shortcomings,the balanced BSP tree is used in the proposed algorithm to accelerate the ray tracing,while the nearest object priority technique(NOP) and in contact surface(ICS) is used to eliminate the repeated rayobject intersection ***,the final criteria of this study are the time consumption as well as accuracy by predicting the field strength and the number of received *** the proposed approaches,our algorithm becomes faster and more accurate than the existing algorithms.A detailed comparative study with existing algorithms shows that the proposed algorithm has at most 37.83%higher accuracy and 34.44%lower time ***,effects of NOP and ICS techniques and scattering factor on time and ray prediction accuracy are also presented.

关键词： rough surface scattering binaryspace partitioning ray tracing nearest objectpriority communications

Analysis of Serious Postoperative Complications of Total Pneumonectomy of Pulmonary Tuberculosis

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Analysis of Serious Postoperative Complications of Total Pne...