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Efficacy of soy protein concentrate replacing animal protein supplements in mucosa-associated microbiota, intestinal health, and growth performance of nursery pigs

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Animal Nutrition 2023年第3期14卷 235-248页

作者： Zixiao Deng marcos Elias Duarte Sung Woo Kim Department of Animal Science North Carolina State UniversityRaleighNC 27695USA

This study investigated the effects of using soy protein concentrate (SPC) to replace animal protein supplements on mucosa-associated microbiota,intestinal health,and growth performance of nursery ***-six newly weaned pigs (BW=6.4±0.6 kg) were allotted to 5 treatments in a randomized complete block *** were fed for 35 d in 3 phases (P;1,2,3) for 10,12,13 d,*** treatments were:(1) basal diet with fish meal (P1:4%,P2:2%,and P3:1%),poultry meal (P1:10%,P2:8%,and P3:4%),and blood plasma (P1:4%,P2:2%,and P3:1%),where SPC replacing none (NC);(2) basal diet with SPC replacing fish meal (RFM);(3) basal diet with SPC replacing poultry meal (RPM);(4) basal diet with SPC replacing blood plasma (RBP);and (5) basal diet with SPC replacing all animal protein supplements (PC).Growth performance was recorded for each *** were euthanized on d 35 to collect jejunal mucosa and tissue to evaluate intestinal health and microbiota,and ileal digesta to measure apparent ileal digestibility (AID) of *** were analyzed using the MIXED procedure of ***,RFM,RPM,and RBP did not affect growth performance,whereas PC decreased (P<0.05) ADG and *** RPM increased (P<0.05) Prevotella stercorea and decreased (P<0.05) Helicobacter *** PC decreased (P<0.05) ***,whilst increasing (P<0.05) Prevotella copri,Propionibacterium acnes,and Pelomonas *** RFM tended to increase (P=0.096) immunoglobulin A in the *** PC tended to decrease (P=0.078) jejunal crypt cell *** were no differences in the villus height,AID of nutrients,intestinal inflammation,and intestinal oxidative stress among *** conclusion,SPC can replace fish meal,poultry meal,or blood plasma individually without affecting growth performance and intestinal health,and AID of nutrients of nursery *** SPC replacing poultry meal benefitted intestinal health by reducing *** and increasing ***,SPC replac

关键词： Blood plasma Fish meal Intestinal health Nursery pigs Poultry meal Soy protein concentrate

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In situ characterizations of solid-solid interfaces in solid-state batteries using synchrotron X-ray techniques

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Carbon Energy 2021年第5期3卷 762-783页

作者： marcos Lucero Shen Qiu Zhenxing Feng School of Chemical Biologicaland Environmental EngineeringOregon State UniversityCorvallisOregonUSA

The solid-solid electrode-electrolyte interface represents an important component in solid-state batteries(SSBs),as ionic diffusion,reaction,transformation,and restructuring could all take *** these processes strongly influence the battery performance,studying the evolution of the solid-solid interfaces,particularly in situ during battery operation,can provide insights to establish the structure-property relationship for *** X-ray techniques,owing to their unique penetration power and diverse approaches,are suitable to investigate the buried interfaces and examine structural,compositional,and morphological *** this review,we will discuss various surface-sensitive synchrotron-based scattering,spectroscopy,and imaging methods for the in situ characterization of solid-solid interfaces and how this information can be correlated to the electrochemical properties of *** goal is to overview the advantages and disadvantages of each technique by highlighting representative examples,so that similar strategies can be applied by battery researchers and beyond to study similar solid-solid interface systems.

关键词： in situ characterizations solid-state battery solid-solid interface synchrotron X-ray

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Computerized geochemical modeling of burial diagenesis of the Eocene turbidite reservoir elements：Urucutuca Formation,Espirito Santo Basin,southeastern Brazil passive margin

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Journal of Palaeogeography 2018年第4期7卷 363-377页

作者： marcos Antonio Klunk Sudipta Dasgupta Rommulo Vieira Conceicao Institute of Isotope Geology Federal University of Rio Grande do SulPorto AlegreBrazil Department of Earth Sciences Indian Institute of Technology (IIT) BombayMumbai India

The computerized geochemical modeling, a useful tool to understand the diagenetic processes influencing the quality of hydrocarbon reservoirs, is performed by using different modules of computer codes based on the thermodynamic and chemical kinetic principles and their associated parameters. As observed in the reservoir lithofacies deposited from the marine sediment-gravity flows, a case study of diagenesis is presented here from the Espírito Santo Basin in southeastern Brazil. The study uses the Geochemist＇s Workbench（GWB～（TM））, PHREEQC～（TM） and TOUGHREACT～（TM） computation packages. The comparison of performances of these packages demonstrates the convergence of results from the software-based geochemical modeling with the petrographic observation of dissolution, albitization, kaolinization, and the precipitation of calcite and dolomite. Moreover, with limited data points, e.g., the sedimentary petrographic data acquired from limited number of boreholes, the computer simulation establishes itself to be a powerful quantitative method estimating the degree and type of diagenetic alteration of turbidite reservoir bodies in contact with a source of saline-water influx associated with salt ***, using the limited petrographic data points, the geochemical computer-simulation method can even be utilized and extrapolated for areas where similar geological context is interpreted but no borehole data are available. Hence, porosity of turbidite reservoir lithofacies can be predicted in relation to the spatial distribution of dissolution, kaolinization, and albitization of feldspars and authigenic carbonate precipitation.

关键词： Sandstone diagenesis Computerized diagenetic modeling Turbidite reservoir GWB PHREEQC TOUGHREACT

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Dietary inclusion of multispecies probiotics to reduce the severity of post-weaning diarrhea caused by Escherichia coli F18+ in pigs

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Animal Nutrition 2021年第2期7卷 326-333页

作者： Yawang Sun marcos E.Duarte Sung Woo Kim Department of Animal Science North Carolina State UniversityRaleighNC27695United States

This study was aimed to determine the efficacy of multispecies probiotics in reducing the severity of post-weaning diarrhea caused by enterotoxigenic Escherichia coli(ETEC)F18+on newly weaned ***-two pigs(16 barrows and 16 gilts,BW=6.99±0.33 kg)at 21 d of age were individually allotted in a randomized complete block design with 2×2 factorial arrangement of *** were selected from sows not infected previously and not vaccinated against *** were fed experimental diets for 25 d based on 10 d phase 1 and 15 d phase *** factors were ETEC challenge(oral inoculation of saline solution or *** F18+at 2×109 CFU)and probiotics(none or multispecies probiotics 0.15%and 0.10%for phase 1 and 2,respectively).Body weight and feed intake were measured on d 5,9,13,19,and *** scores were measured *** samples were taken on d 19 and *** d 25,all pigs were euthanized to obtain samples of digesta,intestinal tissues,and *** tumor necrosis factor alpha(TNFα),malondialdehyde(MDA),peptide YY(PYY),and neuropeptide Y(NPY)were measured in serum and intestinal *** were analyzed using the MIXED procedure of *** fecal score of pigs was increased(P<0.05)by ETEC challenge at the post-challenge *** ETEC challenge decreased(P<0.05)jejunal villus height and crypt depth,tended to increase(P=0.056)jejunal TNFα,increased(P<0.05)ileal crypt depth,and decreased(P<0.05)serum *** probiotics decreased(P<0.05)serum TNFα,tended to reduce(P=0.064)jejunal MDA,tended to increase(P=0.092)serum PYY,and increased(P<0.05)jejunal villus height,and especially villus height-to-crypt depth ratio in challenged *** performance of pigs were not affected by ETEC challenge,whereas the probiotics increased(P<0.05)ADG and ADFI and tended to increase(P-0.069)G:F *** conclusion,ETEC F18+challenge caused diarrhea,intestinal inflammation and morphological damages without affecting the growth *** multispecies probiotics enhanced growth pe

关键词： Escherichia coli Growth performance Gut health Nursery pig Post-weaning diarrhea Probiotic

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Role of short chain fatty acids in gut health and possible therapeutic approaches in inflammatory bowel diseases

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World Journal of Clinical Cases 2022年第28期10卷 9985-10003页

作者： marcos Antônio Ferreira Caetano Patricia Castelucci Department of Anatomy Institute of Biomedical SciencesUniversity of São PauloSão Paulo 05508900SPBrazil

Inflammatory bowel diseases(IBDs) are characterized by inflammation in the gastrointestinal tract and include Ulcerative Colitis and Crohn’s *** diseases are costly to health services,substantially reduce patients’ quality of life,and can lead to complications such as cancer and even *** include abdominal pain,stool bleeding,diarrhea,and weight *** treatment of these diseases is symptomatic,seeking disease *** intestine is colonized by several microorganisms,such as fungi,viruses,and bacteria,which constitute the intestinal microbiota(IM).IM bacteria promotes dietary fibers fermentation and produces short-chain fatty acids(SCFAs) that exert several beneficial effects on intestinal *** can bind to G protein-coupled receptors,such as GPR41 and GPR43,promoting improvements in the intestinal barrier,anti-inflammatory,and antioxidant ***,SCFAs could be a therapeutic tool for ***,the mechanisms involved in these beneficial effects of SCFAs remain poorly ***,this paper aims to provide a review addressing the main aspects of IBDs,and a more detailed sight of SCFAs,focusing on the main effects on different aspects of the intestine with an emphasis on IBDs.

关键词： Ulcerative colitis Crohn’s disease Short-chain fatty acid Butyrate Inflammatory bowel diseases Free fatty acid receptor

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Potential role of the microbiome in liver injury during COVID-19: Further research is needed

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World Journal of Gastroenterology 2023年第3期29卷 503-507页

作者： marcos Roberto Tovani-Palone Paolo Pedersini Department of Research Analytics Saveetha Dental College and HospitalsSaveetha Institute of Medical and Technical Sciences(SIMATS)Chennai 600077India IRCCS Fondazione Don Carlo Gnocchi Milan 20148Italy

Although different studies have associated coronavirus disease 2019(COVID-19)with the occurrence of liver injury,the hepatic injury route during the COVID-19 course is not yet fully *** order to better understand the mechanisms of the disease,the human gut microbiota has been the subject of extensive discussion in the context of COVID-19 ***,many questions remain,including the risks of liver injury due to COVID-19 specific *** research in this field could allow the discovery of new personalized treatment strategies aimed at improving the microbiota composition,thereby reducing COVID-19 severity and its complications in different *** this article,we discussed basic mechanisms of severe acute respiratory syndrome coronavirus 2 infection and recent evidence on the relationship between COVID-19,the gut microbiome and liver injury as well as proposed recommendations for further research.

关键词： COVID-19 Gut microbiota Coronavirus Gut microbial-host-immune axis Gut-lung axis Liver injury

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Guest Editorial:Special Section on Active Distribution Networks:Markets,Operations,Planning,and Regulation

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Journal of Modern Power Systems and Clean Energy 2023年第1期11卷 1-2页

作者： Peter Palensky Qixin Chen marcos J.Rider Delft University of Technology DelftNetherlands Tsinghua University BeijingChina University of Campinas Sao PauloBrazil

THE power system is in change,and the most fundamental changes are happening in the distribution *** passive consumers get active and smart,energy storage and distributed generation appears,and the“grid edge”is upgraded with Intenet of Things(IoT).Gone are the days where distribution infrastructure consisted of passive assets,dimensioned for the worst case of load.

关键词： passive IoT distribution

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Perioperative fluid management in major hepatic resection: an integrative review

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Hepatobiliary & Pancreatic Diseases International 2017年第5期16卷 458-469页

作者： Osamu Yoshino marcos Vinicius Perini Christopher Christophi Laurence Weinberg Department of Surgery Austin Hospital and University of Melbourne Melbourne Victoria Australia Anaesthesia Perioperative Pain Medicine Unit University of Melbourne Melbourne Victoria Australia

BACKGROUND: Fluid intervention and vasoactive pharmacological support during hepatic resection depend on the preference of the attending clinician, institutional resources, and practice culture. Evidence-based recommendations to guide perioperative fluid management are currently limited. Therefore, we provide a contemporary clinical integrative overview of the fundamental principles underpinning fluid intervention and hemodynamic optimization for adult patients undergoing major hepatic resection. DATA SOURCES: A literature review was performed of MEDLINE, EMBASE and the Cochrane Central Registry of Controlled Trials using the terms 'surgery', 'anesthesia', 'starch', 'hydroxyethyl starch derivatives', 'albumin', 'gelatin', 'liver resection', 'hepatic resection', 'fluids', 'fluid therapy', 'crystalloid', 'colloid', 'saline', 'plasma-Lyte', 'plasmalyte', 'hartmann's', 'acetate', and 'lactate'. Search results for MEDLINE and EMBASE were additionally limited to studies on human populations that included adult age groups and publications in English. RESULTS: A total of 113 articles were included after appropriate inclusion criteria screening. Perioperative fluid management as it relates to various anesthetic and surgical techniques is ***: Clinicians should have a fundamental understanding of the surgical phases of the resection, hemodynamic goals, and anesthesia challenges in attempts to individualize therapy to the patient's underlying pathophysiological condition. Therefore, an ideal approach for perioperative fluid therapy is always individualized. Planning and designing large-scale clinical trials are imperative to define the optimal type and amount of fluid for patients undergoing major hepatic resection. Further clinical trials evaluating different intraoperative goal-directed strategies are also eagerly awaited.

关键词： hepatic resection liver resection fluid therapy anesthesia crystalloid colloid goal-directed therapy

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The relationship between fire severity and burning efficiency for estimating wildfire emissions in Mediterranean forests

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林业研究:英文版 2023年第5期34卷 1195-1206页

作者： Bountouraby Balde Cristina Vega-Garcia Pere Joan Gelabert Aitor Ameztegui marcos Rodrigues Department of Agriculture and Forest Engineering University of LleidaAv.Alcalde Rovira Roure19125198 LleidaSpain Department of Geography and Land Management University of ZaragozaPedro Cerbuna 1250009 SaragossaSpain

Forests are exposed to changing climatic conditions reflected by increasing drought and heat waves that increase the risk of wildfire ignition and *** variables such as rain and wind as well as vegetation structure,land configuration and forest management practices are all factors that determine the burning potential of *** assessment of emissions released by vegetation combustion is essential for determining greenhouse gases and air *** estimation of wildfire-related emissions depends on factors such as the type and fraction of fuel(i.e.,live biomass,ground litter,dead wood)consumed by the fire in a given area,termed the burning *** approaches estimate live burning efficiency from optical remote sensing *** study used a data-driven method to estimate live burning efficiency in a Mediterranean *** severity estimations from Lands at imagery(dNBR),which relate to fuel consumption,and quantitative field data from three national forest inventory data were combined to establish the relationship between burning severity and live burning *** proxies explored these relationships based on dNBR interval classes,as well as regres sion *** correlation results between live burning efficiency and dNBR for conifers(R=0.63)and broad-leaved vegetation(R=0.95)indicated ways for improving emissions *** estimations by severity class(low,moderate-low,moderate-high,and high)are provided for conifers(0.44-0.81)and broad-leaves(0.64-0.86),and regression models for the live fraction of the tree canopy susceptible to burning(7 branches,and leaves).The live burning efficiency values by severity class were higher than previous studies.

关键词： Forest wildfires Emissions Greenhouse gases Satellite images

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Combined use of lactoferrin and vitamin D as a preventive and therapeutic supplement for SARS-CoV-2 infection: Current evidence

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World Journal of Clinical Cases 2022年第32期10卷 11665-11670页

作者： Massimiliano Cipriano Enzo Ruberti marcos Roberto Tovani-Palone Department of Laparoscopic Surgery Umberto I General HospitalMedical School Sapienza UniversityRome 161Italy Department of Human Neuroscience Sapienza University of RomeRome 00185Italy Department of Research Analytics Saveetha Dental College and HospitalsSaveetha Institute of Medical and Technical SciencesChennai 600077India

Lactoferrin is a multifunctional protein that exhibits anti-inflammatory,immune regulating and anti-infective *** of its receptor sites is located on severe acute respiratory syndrome coronavirus *** binding of lactoferrin with heparin sulfate proteoglycans may prevent the first contact between the virus and host cells,thus preventing subsequent *** that lactoferrin may act as a natural mucosal barrier,an intranasal treatment together with its oral intake can be hypothesized to prevent the spread,infection and inflammation caused by coronavirus disease 2019(COVID-19).Moreover,the literature reports that vitamin D plays an essential role in promoting immune *** its antiinflammatory and immunoregulatory properties,vitamin D is critical for activating the immune system’s defenses,improving immune cell *** studies also demonstrate that lactoferrin is a potential activator of the vitamin D *** this sense,the combined use of lactoferrin(through an association of oral intake and a nasal spray formulation)and vitamin D could represent a valuable therapy for COVID-19 treatment and ***,further randomized clinical trials are needed before recommending/prescribing them.

关键词： Lactoferrin Vitamin D SARS-CoV-2 COVID-19 Pandemics

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