Potential role of the microbiome in liver injury during COVID-19: Further research is needed

作     者：Marcos Roberto Tovani-Palone Paolo Pedersini 

作者机构：Department of Research AnalyticsSaveetha Dental College and HospitalsSaveetha Institute of Medical and Technical Sciences(SIMATS)Chennai 600077India IRCCS Fondazione Don Carlo GnocchiMilan 20148Italy 

出 版 物：《World Journal of Gastroenterology》 (世界胃肠病学杂志（英文版）)

年 卷 期：2023年第29卷第3期

页      面：503-507页

核心收录：

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

基　　金：the Italian Ministry of Health-Ricerca Corrente 2022 Saveetha Institute of Medical and Technical Sciences for supporting this study 

主　　题：COVID-19 Gut microbiota Coronavirus Gut microbial-host-immune axis Gut-lung axis Liver injury 

摘      要：Although different studies have associated coronavirus disease 2019(COVID-19)with the occurrence of liver injury,the hepatic injury route during the COVID-19 course is not yet fully *** order to better understand the mechanisms of the disease,the human gut microbiota has been the subject of extensive discussion in the context of COVID-19 ***,many questions remain,including the risks of liver injury due to COVID-19 specific *** research in this field could allow the discovery of new personalized treatment strategies aimed at improving the microbiota composition,thereby reducing COVID-19 severity and its complications in different *** this article,we discussed basic mechanisms of severe acute respiratory syndrome coronavirus 2 infection and recent evidence on the relationship between COVID-19,the gut microbiome and liver injury as well as proposed recommendations for further research.