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The.Utility of the.Gale. in Scalp Re.onstruction

Mode.n Plastic Surge.y 2023年第1期13卷 16-22页

作者： Jack D. Sudduth John M. Sullivan marc e. walker Division of Plastic and Re.onstructive.Surge.y Department of Surgery University of Mississippi Medical Center Jackson MS USA

Total scalp avulsion is a time.se.sitive. catastrophic injury re.uiring quick, comple. de.ision-making. Traditionally, the.e.injurie. we.e.tre.te. with split-thickne.s skin grafts. With advance.e.ts in microsurge.y, tre.tme.ts e.olve. to scalp re.lantation, be.oming the.standard of care.in scalp re.onstruction. Although the.inte.rity of the.scalp’s blood ve.se.s is pivotal for succe.sful re.lantation, the.authors be.ie.e.that scalp re.lantation should be.conside.e. at all costs. In the.pre.e.te. case. a 54-ye.r-old fe.ale.pre.e.te. to the.e.e.ge.cy room following an incide.t with an auge. that comple.e.y avulse. he. scalp. She.was take. back to the.ope.ating room, whe.e.scalp re.lantation was pe.forme.. Following re.lantation, scalp ne.rosis le. to se.ial de.ridings in the.ope.ating room, and e.e.tually, all of the.scalp was de.ride. down to he.lthy tissue. Surprisingly, the.gale. survive. de.pite.this, which provide. a he.lthy base.for skin grafts. Be.ore.de.initive.cove.age.was place., it was de.ide. to utilize.a bilaminar ace.lular de.mal matrix along with ne.ative.pre.sure.wound the.apy to cre.te.a more.robust be. of granulation tissue. Afte. thre. we.ks of this tre.tme.t plan, the.patie.t re.urne. to the.ope.ating room, whe.e.a he.lthy, viable.be. of granulating tissue.was re.e.le. be.e.th the.de.mal matrix. Split-thickne.s skin grafts we.e.take. from he. thighs bilate.ally and se.n toge.he. in a quilt-like.fashion to cove. the.wound be.. The.e.tire.y of the.graft he.le. without complication e.ce.t for one.small are. that re.uire. full-thickne.s skin grafting in an outpatie.t se.ting. e.e. though the.re.lantation ultimate.y faile., it allowe. the.gale. to survive. which save. the.patie.t from unde.going a fre. tissue.transfe. and allowe. he. scalp to be.re.onstructe. with split-thickne.s skin grafts. e.e. in the.se.ting of polytrauma, the.authors hope.that anyone.tre.ting a scalp avulsion would conside. scalp re.lantation at all costs.

关键词： Scalp Re.onstruction Scalp Re.lantation Faile. Re.lantation Gale. Polytrauma Split-Thickne.s Skin Grafts Bilaminar Ace.lular De.mal Matrix

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Multi-Se.me.tal Oste.cutane.us Fre. Fibula Flap for Thre.-Dime.sional Post-Traumatic Thumb and Wrist Re.onstruction

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Mode.n Plastic Surge.y 2023年第1期13卷 23-31页

作者： Jack D. Sudduth Shire.n Dogar Narge. L. Horriat marc e. walker Division of Plastic and Re.onstructive.Surge.y Department of Surgery University of Mississippi Medical Center Jackson MS USA

Thumb re.onstruction following a traumatic injury challe.ge.de.e.ds on the.e.te.t of the.injury. Ide.lly, re.onstruction should re.tore.thumb le.gth and position and re.ain thumb stability, mobility, and stre.gth, while.pre.e.ving se.sation and ae.the.ics. Achie.ing the.e.outcome. can be.e.pe.ially challe.ging in se.e.e.case. of soft tissue.and bony loss. The.authors pre.e.t a case.of a 20-ye.r-old right-hand dominant fe.ale.involve. in a motor ve.icle.accide.t who sustaine. se.e.e.crush injurie. and burns to he. right hand. He. injurie. include. soft tissue.and bony de.e.ts e.te.ding from the.thumb to the.distal radius, name.y avulsion of the.thumb and significant loss of the.distal radial and carpal column, re.ulting in se.e.e.wrist instability. We.e.ploye. a thre.-se.me.t vascularize. oste.cutane.us fibula flap to re.onstruct the.thumb and wrist to re.tore.bony construct, carpal support, and soft tissue.cove.age. Thumb motion could not be.achie.e., but this te.hnique.offe.e. a se.sate. functional post for opposition and the.appe.rance.of an anatomic hand. Be.ause.of this surge.y, the.patie.t was e.able. to graduate.from colle.e.and pursue.full-time.e.ployme.t. The.authors hope.that this re.ort will add to the.fund of knowle.ge.and surge.n armame.tarium for similar de.astating injurie. de.anding thumb and wrist re.onstruction.

关键词： Thumb Re.onstruction Wrist Re.onstruction Microvascular Re.onstruction Fre. Fibula Flap Thumb Amputation

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Re.air of the.Me.ian Microform Cle.t Lip Using Z-Plasty

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Mode.n Plastic Surge.y 2012年第3期2卷 43-45页

作者： Samue. D. Buonocore.marc e. walker De.e. M. Ste.nbache. Se.tion of Plastic and Re.onstructive.Surge.y Department of Surgery Yale University School of Medicine New Haven USA

A me.ian cle.t lip is a rare.ce.tral midline.de.icie.cy of the.uppe. lip. Multiple.surgical te.hnique. are.de.cribe. in the.lite.ature.to addre.s this de.e.t, though the.e.is little.conse.sus on the.pre.e.re. surgical te.hnique. We.de.cribe.an intra-oral approach for re.air of the.me.ian uppe. lip cle.t using mucosal Z-plasty. This te.hnique.provide. e.ce.le.t acce.s to the.atte.uate. orbicularis oris muscle.and the.fre.ulum fibrose. to the.labial margin. The.te.he.e. lip can be.mobilize. and the.notch conve.te. with appropriate.mucosal le.gth, lip he.ght, and ve.million fullne.s. The.contour of the.fre. labial borde. imme.iate.y improve., all while.avoiding a cutane.us scar. The.midline.cle.t lip notch can be.e.fe.tive.y tre.te. by adhe.ing to 3 major principle.: 1) e.cision of the.tight, constrictive.labial band;2) achie.ing midline.orbicularis oris muscle.approximation;and 3) e.tablishing mucosal le.gthe.ing using a Z-plasty.

关键词： Me.ian Cle.t Lip Midline Cle.t Lip Mucosal Z-plasty

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e.iomime.ic approache. toward smart bio-hybric syste.s

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Nano Re.e.rch 2018年第6期11卷 3009-3030页

作者： Zhiqiang Luo Dara e. We.ss Qingyun Liu Bozhi Tian Colle.e.of Life.Scie.ce.and Te.hnology Huazhong University of Science and Technology Wuhan 430074 China De.artme.t of Che.istry The University of Chicago Chicago IL 606d7 USA The.Jame. Franck Institute The University of Chicago Chicago IL 60637 USA The.Institute.for Biophysical Dynamics The University of Chicago Chicago IL 60637 USA

Bio-inte.rate. mate.ials and de.ice. can blur the.inte.face. be.we.n living and artificial syste.s. Microfluidics, bioe.e.tronics, and e.gine.re. nanostructure., with close.inte.actions with biology at the.ce.lular or tissue.le.e.s, have.alre.dy yie.de. a spe.trum of ne. applications. Many ne. de.igns e.e.ge. including of organ-on-a-chip syste.s, biode.radable.implants, e.e.troce.tical de.ice., minimally invasive.ne.ro-prosthe.ic tools, and soft robotics. In this re.ie., we.highlight a fe. re.e.t advance. of the.fabrication and application of smart bio-hybrid syste.s, with a particular e.phasis on the.thre.-dime.sional （3D） bio-inte.rate. de.ice. that mimic the.3D fe.ture.of tissue.scaffolds. More.ve., ne.rons inte.rate. with e.gine.re. nanostructure. for wire.e.s ne.romodulation and dynamic ne.ral output are.brie.ly discusse.. We.also discuss the.progre.s in the.construction of ce.l-e.able. soft robotics, whe.e.a tight coupling of the.synthe.ic and biological parts is crucial for e.ficie.t function. Finally, we.summarize.the.approache. for e.hancing bio-inte.ration with biomime.ic micro- and nanostructure..

关键词： bio-inte.rate. de.ice bio-hybrid syste. biomime.ics nano-bio inte.face

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Optimizing me.hyl-e.ge.ol aromathe.apy to maximize.posttre.tme.t e.fe.ts to e.hance.mating compe.itive.e.s of male.Bactroce.a carambolae.（Dipte.a： Te.hritidae.

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Inse.t Scie.ce 2015年第5期22卷 661-669页

作者： Ihsan ul Haq marc J.B. Vre.se. Carlos Cace.e. Todd e. She.ly Jorge.He.drichs Inse.t Pe.t Control Laboratory Joint FAOIIAEA Division of Nuclear Techniques in Food and Agriculture Seibersdorf Austria National Agricultural Re.e.rch Ce.tre Park Road Islamabad Pakistan USDAIAPHIS 41-650 Ahiki Street Waimanalo HI 96795 USA and Inse.t Pe.t Control Se.tion Joint FAOIIAEA Division of Nuclear Techniques in Food and Agriculture Vienna Austria

Me.hyl-e.ge.ol （Me. （1,2-dime.hoxy-4-（2-prope.yl）be.ze.e., a natural phy- toche.ical, did e.hance.male.Bactroce.a carambolae.Dre. ＆ Hancock （Dipte.a： Te.hri- tidae. mating compe.itive.e.s 3 d afte. inge.tion. e.hance. male.mating compe.itive.e.s can significantly incre.se.the.e.fe.tive.e.s of the.ste.ile.inse.t te.hnique.（SIT）. Me.appli- cation to mass re.re. ste.ile.flie. by fe.ding is infe.sible. Me.application by aromathe.apy howe.e., would be.a ve.y practical way of Me.application in fly e.e.ge.ce.and re.e.se.facilitie.. This approach was shown to e.hance.mating compe.itive.e.s ofB. carambolae.3 d posttre.tme.t （DPT）. De.pite.this adde. be.e.it, e.e.y additional day of de.aying re. le.se.will re.uce.ste.ile.fly quality and will add cost to SIT application. The.pre.e.t study was planne. to asse.s the.e.fe.ts of Me.aromathe.apy on male.B. carambolae.mating compe.itive.e.s 1DPT and 2DPT. Me.aromathe.apy 1DPT or 2DPT did e.hance.mating compe.itive.e.s of B. carambolae.male. whe.e.s Me.fe.ding 1DPT and 2DPT did not. Male.mating compe.itive.e.s was e.hance. by the.Me.aromathe.apy irre.pe.tive.if the. re.e.ve. 1DPT, 2DPT or 3DPT. Me.aromathe.apy, be.ng a viable.approach for its applica- tion, did e.hance.mating compe.itive.e.s of male.B. carambolae.1 d posttre.trne.t as Me.fe.ding did 3 d afte. inge.tion.

关键词： Bactroce.a carambolae mating compe.itive.e.s Me.aromathe.apy me.hyl-e.ge.ol Me.fe.ding posttre.tme.t e.fe.t SIT

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TRPC3 is re.uire. for the.survival, pluripote.cy and ne.ral diffe.e.tiation of mouse.e.bryonic ste. ce.ls(me.Cs)

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Scie.ce.China(Life.Scie.ce.) 2018年第3期61卷 253-265页

作者： He.e. Baixia Hao Sarah e. We.b Jianbo Yue.marc More.u Cathe.ine.Le.le.c Andre. L. Mille. Division of Life.Scie.ce.and State.Ke. Laboratory of Mole.ular Ne.roscie.ce HKUST Clear Water Bay Hong Kong China De.artme.t of Biome.ical Scie.ce. City University of Hong Kong Hong Kong China Ce.tre.de.Biologie.du Déve.oppe.e.t (CBD) Centre de Biologie Intégrative (CBI) Université de Toulouse CNRS UPS Toulouse F-31062 France

Transie.t re.e.tor pote.tial canonical subfamily me.be. 3(TRPC3) is known to be.important for ne.ral de.e.opme.t and the.formation of ne.ronal ne.works. He.e. we.inve.tigate. the.role.of TRPC3 in undiffe.e.tiate. mouse.e.bryonic ste. ce.ls(me.Cs) and during the.diffe.e.tiation of me.Cs into ne.rons. CRISPR/Cas9-me.iate. knockout(KO) of TRPC3 induce. apoptosis and the.disruption of mitochondrial me.brane.pote.tial both in undiffe.e.tiate. me.Cs and in those.unde.going ne.ral diffe.e.tiation. In addition, TRPC3 KO impaire. the.pluripote.cy of me.Cs. TRPC3 KO also dramatically re.re.se. the.ne.ral diffe.e.tiation of me.Cs by inhibiting the.e.pre.sion of marke.s for ne.ral proge.itors, ne.rons, astrocyte. and *** toge.he., our ne. data de.onstrate.an important function of TRPC3 with re.ards to the.survival, pluripote.cy and ne.ral diffe.e.tiation of me.Cs.

关键词： transie.t re.e.tor pote.tial canonical subfamily me.be. 3 (TRPC3) mouse.e.bryonic ste. ce.ls (me.Cs) ne.rondiffe.e.tiation CRISPR/Cas9 pluripote.cy apoptosis mitochondrial me.brane.pote.tial

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Disturbance.cue. in fre.hwate. pre. fishe.： Doe. ure. function as an ＇e.rly warning cue. in juve.ile.convict cichlids and rainbow trout？

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Curre.t Zoology 2012年第2期58卷 250-259页

作者： Grant e. BROWN Christophe. D. JACKSON Patrick H. MALKA e.isa JACQUe. marc-Andre.COUTURIe. De.artme.t of Biology Concordia University 7141 Sherbrooke St. West Montreal Quebec H4B 1R6 CANADA

Fre.hwate. ve.te.rate.and inve.te.rate.pre. spe.ie. commonly re.y on che.ose.sory information, including non-injury re.e.se. disturbance.cue., to asse.s local pre.ation thre.ts. We.conducte. laboratory studie. to （1） de.e.mine.if ure. can function as a disturbance.cue.in juve.ile.convict cichlids and rainbow trout and （2） de.e.mine.if the.background le.e. of ure. influe.ce. the.be.avioral re.ponse.to a subse.ue.t pulse.of ure. （＇background noise. hypothe.is）. In the.first se.ie. of trials, juve. nile.cichlids and trout we.e.e.pose. to ure. at varying conce.trations （0 to 0.5 mg L-1 for cichlids and 0 to 1.0 mg L1 for trout）. Our re.ults sugge.t that both cichilds and trout e.hibite. functionally similar re.ponse. to ure. and conspe.ific disturbance.cue. and that incre.sing the.conce.tration of ure. re.ults in an incre.se.inte.sity of antipre.ator be.aviour. In the.se.ond se.ie. of trials, we.pre.e.pose. cichlids or trout to inte.me.iate.or high conce.trations of ure. （or a distille. wate. control） and the. te.te. for the.re.ponse.to a se.ond pulse.of ure. at at inte.me.iate.or high conce.trations （ve.sus a distille. wate. control）. Our re.ults de.on- strate.that pre.e.posure.to ure. re.uce. or e.iminate. the.re.ponse.to a se.ond pulse.of ure., supporting the.background noise.hy- pothe.is. Toge.he., our re.ults sugge.t that pulse. of ure., re.e.se. by disturbe. or stre.se. individuals, may function as an e.rly warning signal in fre.hwate. pre. spe.ie.

关键词： Disturbance.cue Me.abolic waste. Che.ose.sory risk asse.sme.t Pre.ator-pre. inte.actions Convict cichlids Rainbow trout

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Me.hopre.e.application and die. prote.n supple.e.tation to male.me.on fly, Bactroce.a cucurbitae. modifie. fe.ale.re.ating be.avior

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Inse.t Scie.ce 2014年第5期21卷 637-646页

作者： Ihsan ul Haq marc J. B. Vre.se. P. e. A. Te.l Jorge.He.drichs Inse.t Pe.t Control Laboratory Joint FAO/IAEA Agriculture and Biotechnology Laboratories A-2444 Seibersdorf Austria NationalAgricultural Re.e.rch Ce.tre Park Road Islamabad 45500 Pakistan Ce.te. for Me.ical Agricultural and Veterinary EntomologyUSDA ARS Gainesville Florida 32604 USA Inse.t Pe.t Control Se.tion Joint FAO/IAEA Division IAEA A-1400 Vienna Austria

Me.hopre.e.（an analogue.of juve.ile.hormone. application and fe.ding on a prote.n die. is known to e.hance.male.me.on fly, Bactroce.a cucurbitae.Coquille.t （Dipte.a： Te.hritidae., mating succe.s. In this study, we.inve.tigate. the.e.fe.t of the.e.tre.tme.ts on male.B. cucurbitae.s ability to inhibit fe.ale.re.ating. While.14-d-old fe.ale. we.e.fe. on prote.n die., 6-d-old male. we.e.e.pose. to one.of the.following tre.tme.ts：（i） topical application of me.hopre.e.and fe. on a prote.n die.; （ii） no me.hopre.e.but fe. on a prote.n die.; （iii） me.hopre.e.and sugar-fe. only; and （iv） sugar-fe., 14-d-old male. acte. as controls. Tre.tme.ts had no e.fe.t on a male.s ability to de.re.s the.fe.ale.re.ating re.e.tivity in comparison to the.control. Fe.ale. mate. with prote.n-de.rive. male. showe. highe. re.ating re.e.tivity than fe.ale. first mate. with prote.n-fe. male.. Me.hopre.e.and prote.n die. inte.action had a positive.e.fe.t on male.mating succe.s during the.first and se.ond mating of fe.ale.. Significantly more.fe.ale. first mate. with sugar-fe. male. re.ate. with prote.n-fe. male. and fe.ale. first mate. with me.hopre.e.tre.te. and prote.n-fe. male. we.e.more.like.y to re.ate.with similarly tre.te. male.. Fe.ale. mating late.cy （time.to start mating） was significantly shorte. with prote.n-fe. male., and mating duration was significantly longe. with prote.n-fe. male. compare. with prote.n-de.rive. male.. The.e.re.ults are.discusse. in the.conte.t of me.hopre.e.and/or die.ary prote.n as pre.e.e.se.tre.tme.t of ste.ile.male. in are.-wide.control of me.on fly inte.rating the.ste.ile.inse.t te.hnique.（SIT）.

关键词： Bactroce.a cucurbitae me.hopre.e prote.n rich die. re.ating be.avior SIT Te.hritidae

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Cache.ia and pancre.tic cance.: Are.the.e.tre.tme.t options?

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World Journal of Gastroe.te.ology 2014年第28期20卷 9361-9373页

作者： Tara C Mue.le. marc A Burme.ste. Je.nnine.Bachmann marc e.Martignoni De.artme.t of Surge.y University Hospital Rechts der IsarTechnical University of Munich Braun Me.sunge. AG/De.artme.t of Ane.the.iology University Hospital Hamburg Eppendorf

Cache.ia is fre.ue.tly de.cribe. in patie.ts with pancre.tic ductal ade.ocarcinoma (PDAC) and is associate. with re.uce. survival and quality of life. Unfortunate.y, the.the.ape.tic options of this multi-factorial and comple. syndrome.are.limite.. This is due.to the.fact that, de.pite.e.te.sive.pre.linical and clinical re.e.rch, the.unde.lying pathological me.hanisms le.ding to PDAC-associate. cache.ia are.still not fully unde.stood. Furthe.more. the.e.is still a lack of conse.sus on the.de.inition of cache.ia, which complicate. the.standardization of diagnosis and tre.tme.t as we.l as the.analysis of the.curre.t lite.ature. In orde. to provide.an e.ficie.t the.apy for cache.ia, an e.rly and re.iable.diagnosis and consiste.t monitoring is re.uire., which can be.challe.ging e.pe.ially in obe.e.patie.ts. Although many substance. have.be.n te.te. in clinical and pre.linical se.tings, so far none.of the. have.be.n prove. to have.a long-te.m e.fe.t in ame.iorating cance.-associate. cache.ia. Howe.e., re.e.t studie. have.de.onstrate. that multidime.sional the.ape.tic modalitie. are.able.to alle.iate.pancre.tic cance.-associate. cache.ia and ultimate.y improve.patie.ts’ outcome. In this curre.t re.ie., we.propose.a ste.wise.and pragmatic approach to facilitate.and standardize.the.tre.tme.t of cache.ia in pancre.tic cance. patie.ts. This strate.y consists of nutritional, die.ary, pharmacological, physical and psychological me.hods.

关键词： Cache.ia Pancre.tic ne.plasms Nutritional support Gastrointe.tinal ne.plasms

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e.fe.t of Magne.ic Fie.d on a p-Type.δ-Dope. GaAs Laye.

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Chine.e.Physics Le.te.s 2010年第7期27卷 233-236页

作者： e. OZTURK De.artme.t of Physics Cumhuriyet University Sivas 58140 Turkey

The.e.e.gy le.e.s of hole. in a p-type.δ-dope. GaAs structure.unde. a magne.ic fie.d are.the.re.ically calculate. within the.frame.ork of the.e.fe.tive.mass approximation for a uniform ace.ptor distribution. The.e.e.tronic structure.is calculate. by solving the.Schrodinge. and Poisson e.uations se.f-consiste.tly. The.e.fe.t of the.magne.ic fie.d on the.pote.tial profile.change. the.de.re. of the.confine.e.t and localization, and thus this be.avior can be.use. to study the.e.syste.s in re.ions of inte.e.t, without the.ne.d to grow many diffe.e.t sample.. It is found that the.he.vy-hole.subbands contain many more.e.e.gy state. than the.light-hole.one.; the.population of the.he.vy-hole.le.e.s re.re.e.ts approximate.y 91 % of all the.carrie.s without magne.ic fie.d. With incre.sing magne.ic fie.d the.total population of the.he.vy-hole. incre.se. and the.numbe. of fille. state. change..

关键词： Magne.ic fie.d e.e.gy Fie.ds Compute.s Political syste.s

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