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NAPHTHALIMIDE BASED DISPERSE DYES FOR NYLON 6 AND POLYESTER(PET) FIBERS:SYNTHESIS AND EVALUATION OF TECHNICAL PROPERTIES IN THE PRESENCE OF UREA

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Chinese Journal of Polymer Science 2011年第6期29卷 712-718页

作者： javad Mokhtari mahdi Nouri Uranus Goudarzi Department of Textile Engineering Faculty of EngineeringUniversity of GuilanRashtIran

Technical properties of two naphthalimide based disperse dyes on nylon 6 and polyester fibers were investigated in the presence of urea. The two naphthalimide based disperse dyes were synthesized. The dyes were purified and then fully characterized using 1H-NMR, FTIR and melting point analysis. Dispersion of the dyes was prepared in water and applied on nylon 6 and PET fibers. The dyes offered good build-up properties on the substrates. In order to increase dye adsorption of the substrates, urea was added into the dyebath. By adding urea, the dye adsorption of polyester was increased significantly, while the increase of that of nylon 6 was not marked. The dyes showed good fastness properties on the substrates.

关键词： Naphthalimide Nylon 6 Polyester Urea Disperse dye

ELECTROSPINNING OF CYCLODEXTRIN FUNCTIONALIZED CHITOSAN/PVA NANOFIBERS AS A DRUG DELIVERY SYSTEM

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Chinese Journal of Polymer Science 2013年第10期31卷 1343-1351页

作者： Maryam Bazhban mahdi Nouri javad Mokhtari Department of Textile Engineering Faculty of Engineering University of Guilan

A new type ofnanofibrous structure from chitosan bearing carboxymethyl-β-cyclodextrin （CS-g-β-CD） as a novel drug delivery system was synthesized by grafting carboxymethyl-β-cyclodextrin （CM β-CD） onto chitosan （CS） in the presence of water soluble 1-ethyl-3-（3-dimethylaminopropyl） carbodiimide （EDC） as the condensing agent and N-hydroxysuccinimide （NHS）. Defect free mats containing CS-g-β-CD have been fabricated using electrospirming of an aqueous solution of poly（vinyl alcohol）（PVA）/CS-g-β-CD blends. The morphology and diameter of the electrospun nanofibers were examined by scanning electron microscopy （SEM）. The average fiber diameter was in the range of 130-210 run. SEM images showed that the morphology and diameter of the nanofibers were mainly affected by weight ratio of the blend at constant applied voltage. The results revealed that increasing CS-g-β-CD content in the blends decreases the average fiber diameter. It was observed that the PVA/CS-g-β-CD nanofibrous mat provided a slower release of the entrapped drug in compare to PVA/CS nanofibrous mat.

关键词： Chitosan βcyclodextrin Nanofibers Drug delivery.

Design and optimization of nano-antenna for thermal ablation of liver cancer cells

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Chinese Physics B 2021年第4期30卷 574-585页

作者： Mohammad javad Rabienejhad Azardokht Mazaheri mahdi Davoudi-Darareh Optics and Laser Science and Technology Research Center Malek Ashtar University of TechnologyShahinshahrIran Department of Physics University of IsfahanIran Faculty of Science Malek Ashtar University of TechnologyShahinshahrIran

One method of cancer therapy is to utilize nano-antenna for thermal *** this method,the electromagnetic waves emitted from the nano-antenna are absorbed by the tissue and lead to heating of cancer *** temperature of cancer cells reaches a threshold,they will begin to *** this purpose,an L-shaped frame nano-antenna(LSFNA) is designed to introduce into the biological ***,the radiation characteristics of the LSFNA such as near and far-field intensities,directivity,and sensitivity to its gap width are studied to the optimization of the *** bio-heat and Maxwell equations are solved using the finite element *** prevent damage to healthy tissues in this method,the antenna radiation must be completely controlled and performed ***,penetration depth,special absorption rate,temperature distribution,and the fraction of tissue necrosis are analyzed in the biological *** is why the design and optimization of the nano-antennas as a radiation source is ***,a pulsed source is used to excite the ***,focusing and efficiency of the nano-antenna radiation on the cancer cell is tuned using an adjustable liquid crystal *** focus of this lens is changing under an electric field applied to its surrounding cathode.

关键词： cancer therapy directivity far-field intensity hyperthermia liver cancer nano-antenna thermalablation tunable liquid crystal lens

Structural Control on the Salmas Geothermal Region, Northwest Iran, from Fractal Analysis and Paleostress Data

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Acta Geologica Sinica(English Edition) 2018年第5期92卷 1728-1738页

作者： mahdi BEHYARI javad NOURALIEE Davar EBRAHIMI Department of Geology Faculty of Sciences Urmia University Renewable Energy Department Niroo Research Institute (NRI)

The Salmas geothermal field is located in NW Iran. Subduction of Neo-Tethys oceanic crust beneath the Iranian microcontinent caused to propagation of the magmatic-Arc. Fractures and faults in the convergent zone have created path-ways for the circulation of geothermal fluid. Fracture concentration in the Salmas geothermal field has been characterized using of the fractal method and creation of a fracture density map that shows the highest concentration in the central part of the study area. The permeability of fractures has been evaluated by analyzing their orientation in respect to the paleostress axes. Also, the fractal analyzing result indicates the maximum fractal dimension（1.96） is around the thermal spring outlet. Paleostress analyzing revealed that in the central part of the study area, σ1 axes orientation is S90°W/10° and the σ2 dip is near to the vertical in this stress field, where strike slip faults can be propagated. In the SE part near the recharge of the thermal springs, the σ3 plunge increases to 70？ and σ1 orientation is N15°E/20°, in this local tectonic regime thrust fault developed. Fractures have an important role in the circulation of fluid and the fractal dimension increases near the thermal springs in the Salmas geothermal field. Regarding the paleostress data fracture with N-S direction such as the F1 fault zone（parallel to the σ1 axes）, a suitable pathway for deep circulation of geothermal fluid flow has been created.

关键词： lineament extraction fractal method geothermal field paleostress Salmas NW Iran

Quenching effect of deferoxamine on free radical-mediated photon production in luminol and ortho-phenanthroline-dependent chemiluminescence

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Chinese Chemical Letters 2014年第4期25卷 630-634页

作者： mahdi Parvar Jalil Mehrzadn Mohammad javad Chaichi Saman Hosseinkhani Hamid Golchoubian Faculty of Chemistry Mazandaran University Department of Pathobiology Faculty of Veterinary MedicineFerdowsi University of Mashhad Veterinary Biotechnology Research Group Institute of BiotechnologyFerdowsi University of Mashhad Department of Biochemistry Faculty of Biological SciencesTarbiat Modares University

Removing excessive free radicals （FRs） by a synthetic chemical might give a clue for treatment of many iron-mediated diseases. Deferoxamine （DFO） can be one of the chemicals of choice for the clue. To investigate photoredox properties of DFO, its quenching effect on superoxide radical （O2°）, hydrogen peroxide （H202） and hydroxyl radical （OH~） was examined using luminol and ortho-phenanthroline （o- phen） chemiluminescence （CL） systems and UV-vis spectrophotometry. Stern-Volmer equation was also used for the CL kinetics. The observed quenching effect of DFO on CL]photon production in luminol and o-phen CL systems strongly confirmed the static arm of quenching properties of DFO on OH° and H2O2, but much less pronounced on O2^-°; the quenching property was maximal when iron was involved in the reaction systems. The Stern-Volmer plots in the designed photochemical reaction systems also confirmed a potent quenching effect of DFO on FR-mediated CL. Our study highlights strong photoreducing and antioxidant properties of DFO with huge quenching capacity on excessive FRs, and thus implies its promising prospects for therapeutic applications.

关键词： Chemiluminescence Deferoxamine Free radicals Photon production Stern-Volmer plot

Role of architectural space in blast-resistant buildings

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Frontiers of Architectural Research 2013年第1期2卷 67-73页

作者： mahdi Bitarafan Sayed Bagher Hosseini Sayed javad hashemi-fesharaki Armin Esmailzadeh Department of Civil Engineering Engineering Research Institution of Natural Disaster Shakhes Pajouh Isfahan Iran School of Architecture and Environmental Design Iran University of Science and Technology Tehran Iran Department of Passive Defense University of Imam-Hossein Tehran Iran MSc student at Structural Engineering Faculty of Engineering Central Tehran Branch Azad University (IAUCTB) Tehran Iran

The design of all spatial scares in a manufactured environment is part of the architectural skills and knowtedge. Therefore, an architectural design should be drafted to reduce the vulnerability of humans and buildings against unexpected events, such as terrorist attacks and bombardments. Human casualties and equipment destruction inside the buitdings coutd be prevented by designing a suitabte architectural space. This study addresses the absence of a codified and detaited criterion to evatuate architecturat spaces and their design. Hence, art proposed indices for architectural spaces have been extracted using the ideas of experts in the field of architecture and exptosives. Questionnaires were presented to 25 experts to weigh the effective indices using the anatytic hierarchy process method. The human-oriented （ergonomic） characteristics of the buitding space is found to be the most important factor in facilitating crisis management, followed by the Location of criticat spaces.

关键词： Architectural space Building Explosion Index

Promising antileishmanial effectiveness of doxorubicin and Doxil against Leishmania major:An in vitro assay

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Asian Pacific Journal of Tropical Medicine 2017年第6期10卷 614-618页

作者： Azar Shokri javad Akhtari Masoud Keighobadi mahdi Fakhar Saeed Hosseini Teshnizi Saeed Emami Sajede Sadjjadian Students Research Committee Department of Parasitology and MycologySchool of MedicineMazandaran University of Medical SciencesSariIran Immunogenetic Research Center Department of Physiology and PharmacologyFaculty of MedicineMazandaran University of Medical SciencesSariIran Pharmaceutical Sciences Research Center Faculty of Pharmacy Mazandaran University of Medical SciencesSariIran Molecular and Cell Biology Research Center Department of Parasitology and MycologySchool of MedicineMazandaran University of Medical SciencesSariIran Clinical Research Development Center of Children Hospital Hormozgan University of Medical SciencesBandar AbbasIran

Objective: To evaluate the effect of doxorubicin and its pegylated liposomal formulation(Doxil, Caelyx) on in vitro susceptibility of promastigote and amastigote stages of Leishmania major. Methods: Throughout in vitro assays the IC50 was calculated in the promastigotes and amastigotes forms in J774 macrophage cell line. Also as cytotoxicity in J774 cell line macrophages. Results: Doxorubicin and Doxil showed the same activity against promastigote form with IC50 values of 10.49 μg/m L and 9.63 μg/m L, respectively. Similarly, the amastigote stage was susceptible at concentration of at least 1 μg/m L when compared to positive control(P<0.000 1). Also, cytotoxicity assay against macrophage revealed no toxicity on the host cells at IC50 concentrations. Conclusions: Our findings demonstrated the efficacy of both doxorubicin and its pegylated liposomal formulation on Leishmania major at low concentrations. Further researches are needed for evaluating the safety of drugs in animal model particularly as topical formulation.

关键词： Leishmania major doxorubicin Doxil In vitro

Design and optimization of a nano-antenna hybrid structure for solar energy harvesting application

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Chinese Physics B 2021年第9期30卷 606-617页

作者： Mohammad javad Rabienejhad mahdi Davoudi-Darareh Azardokht Mazaheri Optics and Laser Science and Technology Research Center Malek Ashtar University of TechnologyShahinshahrIran Faculty of Science Department of PhysicsMalek Ashtar University of TechnologyShahinshahrIran Department of Physics University of IsfahanIran

A novel hybrid structure with high responsivity and efficiency is proposed based on an L-shaped frame nano-antenna(LSFNA)array for solar energy harvesting ***,two types of LSFNAs are designed and optimized to enhance the harvesting characteristics of traditional simple electric dipole nano-antenna(SEDNA).The LSFNA geometrical dimensions are optimized to have the best values for the required input impedance at three resonance wavelengths ofλ_(res)=10μm,15μm,and 20μ*** the LSFNAs with three different sizes are modeled like a planar spiral-shaped array(PSSA).Also,a fractal bowtie nano-antenna is connected with the PSSA in the array *** proposed hybrid structure consists of two main elements:(I)Three different sizes of the LSFNAs with two different material types are designed based on the thin-film metal-insulator-metal diodes that are a proper method for infrared energy harvesting.(Ⅱ)The PSSA gap is designed based on the electron field emission proposed by the Fowler-Nordheim theory for the array ***,the proposed device is *** results show that the PSSA not only has an averaged 3-time enhancement in the harvesting characteristics(such as return loss,harvesting efficiency,etc.)than the previously proposed structures but also is a multi-resonance wide-band ***,the proposed antenna takes up less space in the electronic circuit and has an easy implementation process.

关键词： field electron emission infrared metal-insulator-metal(MIM)diode nano-antenna photovoltaic effects rectification solar energy harvesting

Procedure for determining the number of thermal diffusion columns in square cascade for separation of Ne stable isotopes

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Nuclear Science and Techniques 2023年第5期34卷 47-55页

作者： Fatemeh Mansourzadeh Mohammad mahdi Shadman javad Karimi Sabet Valiyollah Ghazanfari Nuclear Fuel Cycle Research School Nuclear Science and Technology Research InstituteTehranIran

The thermal diffusion column represents one method of separating stable *** method is advantageous for smallscale operations because of the simplicity of the apparatus and small inventory,especially in gas-phase ***,it has attracted attention for its applicability in tritium and noble gas separation *** this study,the R cascade was used to design and determine the number of columns.A square cascade was adopted for the final design because of its flexibility,and calculations were performed to separate 20Ne and 22Ne *** the R cascades that enriched the Ne isotopes by more than 99%were investigated,the number of columns was determined,and the square cascade parameters were optimized using the specified ***,a calculation code“RSQ_CASCADE”was developed.A unit separation factor of three was considered,and the number of studied stages ranged from 10 to *** results showed that the column separation power,relative total flow rate,and required number of columns were linearly related to the number of *** separation power and relative total flow decreased and the number of columns increased as the stage number ***,a cascade of 85 columns is recommended to separate the stable Ne *** calculations yielded a 17-stage square cascade with five columns in each *** changing the stage cut,feed point,and cascade feed flow rate,the best parameters for the square cascade were determined according to the cascade and column separation *** the column separation power had a maximum value in cascade feed 50,it was selected for separating Ne isotopes.

关键词： Stable isotope Thermal diffusion Cascade Separation Neon