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Verification of Lactobacillus brevis tolerance to simulated gastric juice and the potential effects of postbiotic gamma-aminobutyric acid in streptozotocin-induced diabetic mice

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Food Science and Human Wellness 2022年第1期11卷 165-176页

作者： Amro Abdelazez Heba Abdelmotaal Smith Etareri Evivie maha Bikheet Rokayya Sami hassan Mohamed Xiangchen Meng Key Laboratory of Dairy Science Ministry of EducationCollege of Food SciencesNortheast Agricultural UniversityHarbin 150030China College of Agriculture and Forestry Linyi UniversityLinyi 276005China Department of Dairy Microbiology Animal Production Research InstituteAgriculture Research CentreDokkiGiza 12618Egypt Department ofMicrobiology SoilWaterEnvironmentand Microbiology Research InstituteAgriculture Research CentreGiza 12619Egypt Department of Food Science&Hunan Nutrition Faculty of AgricultureUniversity of BeninBenin City 300001Nigeria Department of Dairy Science Faculty of AgricultureMinia UniversityMinia 61511Egypt Department of Food Science and Nutrition College of SciencesTaif UniversityP.O.11099Taif21944Saudi Arabia Colin Ratledge Center for Microbial Lipids School of Agriculture Engineering and Food ScienceShandong University of TechnologyZibo 255049China Department of Botany and Microbiology Faculty of ScienceAl-Azhar UniversityAssiut 71524Egypt

The therapeutic effect of gamma-aminobutyric acid(GABA)on diabetes was spread as one of the alarming epidemics *** study aims to investigate the function of Lactobacillus brevis KLDS_(1.0727) and KLDS_(1.0373) strains as glutamic acid decarboxylase 65(GAD65)carriers capable of generating GABA by comparing in vitro free and freeze-dried models and GABA intervention in *** amplification of gad and in vitro i.e.,(growth rate,viability at different pH,bile tolerance,and survivability in simulated gastric juice)were *** vivo experiments were conducted in 7 groups of C57BL/6J *** group was injected with streptozotocin(Cont_(STZ),INSSTZ,LAC1_(STZ),LAC_(1MFDSTZ),LAC_(2STZ),LAC_(2MFDSTZ))daily except for the control(Cont).One group was injected with insulin(INSSTZ).The body weight and hyperglycemia in the blood were assessed weekly,post-euthanasia blood plasma parameters,insulin,and histological examination were *** indicated *** strains demonstrated a great tolerance to bile and simulated gastric juice in vitro(P<0.05).Cont_(STZ) had the highest average glucose level(6.84±6.46)mmol/L while INS_(STZ) expressed dramatically decreed in glucose level and displayed a significant decline in the average of weekly blood glucose(−5.74±3.08)mmol/*** lowest body weight(ContSTZ)was(19.30±0.25)*** on the blood plasma analysis,*** strains improved good cholesterol properties,liver and kidney functions,where most of these parameters fall within the average the reference range and prevent the development of symptoms of type 1 diabetes in *** recommended,*** should be commonly distributed as a postbiotic GABA in pharmaceutical and nutritional applications.

关键词： Diabetes Gamma-aminobutyric acid Postbiotics Lactobacillus brevis In vitro C57BL/6J mice

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Inter-Calibration Between Plasma Instruments Onboard DEMETER

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Plasma Science and Technology 2008年第5期10卷 539-545页

作者： maha S.QUASSIM National Research Institute of Astronomy and Geophysics Helwan 11421CairoEgypt

The in-situ measurements of the ionospheric plasma that we use come from two instruments of the scientific payload of the satellite DEMETER; the plasma analyser IAP （Instrument d＇analyse du plasma） and the Langmuir probe ISL （Instrument Sonde de Langmuir）. DEMETER is a micro-satellite realized by the CNES（Centre National d＇Etudes Spatiales, France） with a principal objective to seek a possible influence of the seismic activity on the electromagnetic waves in the ionosphere and on the ionospheric plasma. The satellite was placed on June 29, 2004, in a circular and quasi helio-synchronous orbit at -710 km altitude. The experiments function primarily at mid-latitudes （from ＋60° to -60°）. The IAP data were analysed to deduce the ion population （densities of the dominant ions, i.e. generally O^＋, H^＋ and He^＋） therefore the total ion density. The use of data IAP thus requires some precaution to make sure that the electric equilibrium conditions of the satellite, such as the satellite potential （Фsat）, are obtained during the treatment of routine, does not induce an error of measurement. When this potential is negative, the minority light ions H^＋ and He^＋ can be measured in a reliable way when their proportion is above 3% to 5% of that of O^＋. The critical limitation is： under certain conditions, the satellite potential becomes positive and reach a value about -0.5 V so that it becomes impossible to measure H^＋ ions. This is likely to involve a significant error on the composition and the density of the plasma. Therefore we carried out a calibration to estimate the missing density. The ISL experiment （Langmuir probe） provided the collected current/polarized tension characteristics of a cylindrical probe from which both electron density Ne and temperature Te were obtained. In some situations it is necessary to examine the accuracy of the electron density using another technique, for instance the high frequency （HF） spectrogram, provided by ICE （instrument champ electrique

关键词： plasma analyser satellite plasma observation ion density measuring

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In flue nee of microwave drying and con venti onal drying methods on the mechanical properties of naproxen sodium drug tablets

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Particuology 2020年第6期18卷 30-40页

作者： maha Al-Ali Rajarathinam Parthasarathy Chemical and Environmental Engineering School of EngineeringRM1T UniversityMelbourneVictoria 3001Australia

Tablets are one of the most comm only used solid dosage forms taken by *** preparati on of high-quality tablets requires an understanding of the preparation process and elucidation of how the physical and mechanical properties change as a function of the preparation *** work aims to investigate the impact of microwave irradiation drying and conventional drying methods(including freeze,convective and vacuum drying)on the hardness,tensile strength and friability of tablets made from a multi-component formulation containing naproxen sodium,microcrystalline cellulose,and *** results show that tablets subjected to microwave drying had the secondhighest tensile strength and hardness of 1.296 MPa and 67 N,*** tablets subjected to vacuum drying had the lowest tensile strength and hardness of 1.21 MPa and 64 N,*** friability index values for the tablets derived from the microwave and freeze-drying methods werel%.Microwave drying was observed to be an efficient method to produce naproxen sodium-containing tablets with satisfactory mechanical *** findings confirm that the drying method plays an essential role in the improvement or degradation of the mechanical properties of tablets.

关键词： Microwave drying Naproxen sodium Hardness Friability Tensile strength

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Experimental and Numerical Analysis of Restrained Early Age Cracking based on Electrical Resistivity Using Eccentric Sample

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Journal of Wuhan University of Technology(Materials Science) 2018年第6期33卷 1472-1480页

作者： maha A Abusogi WEI Xiaosheng School of Civil Engineering and Mechanics Huazhong University of Science and Technology

Crack potential and hydration processes of the cement pastes were monitored using an upto-date eccentric steel cracking frame(ESCF), associated with the non-contact electrical resistivity apparatus, independently. The objective of employing the ESCF is to give a new method determining cracks of concrete at early age. The findings indicate that the lowest water-cement ratio paste reveals highest resistivity values, compasses an earlier inflection point and obtained higher stress. The eccentric restrained cracking test exhibited that lower water-cement ratio paste cracked at the earliest time, accordingly confirms cracking tendency is the highest. Tensile strength test and stresses utilizing ABAQUS simulation was performed. The crack initiation ages obtained are consistent with the experimental program results, which indicates that ABAQUS numerical analysis can well be utilized to predict the crack tendency of cement.

关键词： eccentric steel cracking frame electrical resistivity cracking time hydration numerical analysis

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Arabic Named Entity Recognition:A BERT-BGRU Approach

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Computers, Materials & Continua 2021年第7期68卷 471-485页

作者： Norah Alsaaran maha Alrabiah Department of Computer Science Imam Muhammad Ibn Saud Islamic UniversityRiyadhSaudi Arabia

Named Entity Recognition(NER)is one of the fundamental tasks in Natural Language Processing(NLP),which aims to locate,extract,and classify named entities into a predefined category such as person,organization and *** of the earlier research for identifying named entities relied on using handcrafted features and very large knowledge resources,which is time consuming and not adequate for resource-scarce languages such as ***,deep learning achieved state-of-the-art performance on many NLP tasks including NER without requiring hand-crafted *** addition,transfer learning has also proven its efficiency in several NLP tasks by exploiting pretrained language models that are used to transfer knowledge learned from large-scale datasets to domain-specific *** Encoder Representation from Transformer(BERT)is a contextual language model that generates the semantic vectors dynamically according to the context of the *** architecture relay on multi-head attention that allows it to capture global dependencies between *** this paper,we propose a deep learning-based model by fine-tuning BERT model to recognize and classify Arabic named *** pre-trained BERT context embeddings were used as input features to a Bidirectional Gated Recurrent Unit(BGRU)and were fine-tuned using two annotated Arabic Named Entity Recognition(ANER)*** results demonstrate that the proposed model outperformed state-of-the-art ANER models achieving 92.28%and 90.68%F-measure values on the ANERCorp dataset and the merged ANERCorp and AQMAR dataset,respectively.

关键词： Named entity recognition Arabic deep learning BGRU BERT

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Comparative analyses/evaluation of the textural properties of naproxen sodium tablets and powders prepared using microwave and other drying techniques

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Particuology 2020年第3期18卷 197-204页

作者： maha Al-Ali Selvakannan Periasamy Rajarathinam Parthasarathy Chemical and Environmental Engineering School of EngineeringRMIT UniversityMelbourneVictoria 3000Australia Applied Chemistry School of ScienceRMIT UniversityMelbourneVictoria 3000Australia

The properties of oral tablets are normally related to the properties of the powders they *** of oral tablets is important for the development of tablets with rapid and safe release of the active *** this study,a new formulation of naproxen sodium was prepared and dried using microwave drying (MWD) and the following conventional drying techniques:freeze-drying (FD),vacuum drying (VD),and convective drying (CD).The reference drug powder (RDP) and dry granules MWG,CDG,VDG,and FDG,which were dried using MWD,CD,VD,and FD,respectively were compressed to form tablets labeled RF-TAB,MW-TAB,CD-TAB,VD-TAB,and FD-TAB,*** dry granules and prepared tablets were characterized using Fourier transform infrared spectrometry,scanning electron microscopy,and X-ray *** study aimed to explore the correlation between the textural characteristics of the tablets and their respective powders for different drying *** the morphologies of the dry particles were irregular,the prepared tablets were smooth and flat with few *** increased the amorphous nature of the granules but decreased their *** crystallinities of all tablets,except those prepared by VD,decreased after *** summary,the characteristics of the prepared tablets were acquired from their respective powders.

关键词： Naproxen sodium Microwave drying Tablet Texture Crystallinity

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LRV: A Tool for Academic Text Visualization to Support theLiterature Review Process

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Computers, Materials & Continua 2019年第6期59卷 741-751页

作者： Tahani Almutairi maha Al-yahya Information Technology Department College of Computer and Information SciencesKing Saud UniversityDeriyah CampusRiyadh 11451Saudi Arabia Information Technology Department College of Computer and Information SciencesKing Saud.UniversityDeriyah CampusRiyadh 11451Saudi Arabia

Text visualization is concerned with the representation of text in a graphicalform to facilitate comprehension of large textual data. Its aim is to improve the ability tounderstand and utilize the wealth of text-based information available. An essential task inany scientific research is the study and review of previous works in the specified domain,a process that is referred to as the literature survey process. This process involves theidentification of prior work and evaluating its relevance to the research question. With theenormous number of published studies available online in digital form, this becomes acumbersome task for the researcher. This paper presents the design and implementationof a tool that aims to facilitate this process by identifying relevant work and suggestingclusters of articles by conceptual modeling, thus providing different options that enablethe researcher to visualize a large number of articles in a graphical easy-to-analyze *** tool helps the researcher in analyzing and synthesizing the literature and building aconceptual understanding of the designated research area. The evaluation of the toolshows that researchers have found it useful and that it supported the process of relevantwork analysis given a specific research question, and 70% of the evaluators of the toolfound it very useful.

关键词： Text visualization information extraction text mining literature review

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Immunity,feed,and husbandry in fish health management of cultured Epinephelus fuscoguttatus with reference to Epinephelus coioides

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Aquaculture and Fisheries 2018年第2期3卷 51-61页

作者： Catherine Cheng Yun Chieng hassan M.Daud Fatimah M.Yusoff maha Abdullah Laboratory of Marine Biotechnology Institute of BioscienceUniversiti Putra MalaysiaSerdang 43400Malaysia Department of Veterinary Clinical Studies Faculty of Veterinary MedicineUniversiti Putra MalaysiaSerdang 43400Malaysia Department of Pathology Faculty of Medicine and Health SciencesUniversiti Putra MalaysiaSerdang 43400Malaysia

Groupers are dispersed worldwide in the tropical and subtropical *** are prized in the live reef fish trade,making them candidates with high market value and consumer *** the Asian-Pacific region,the brown-marbled grouper(Epinephelus fuscoguttatus)is widely adapted as an aquaculture ***,health management remains a major concern in the stressful intensive culture *** present review discusses techniques and current knowledge in the cultivation of *** towards healthy fish growth focusing on aspects of immunity,feed,and *** how the fish immune system responds during infections provides insights into the intricate ways fish resist *** information is helpful when developing vaccination strategies or immunostimulant compounds to strengthen fish *** that are formulated according to the needs of the fish ensure optimal growth and using suitable alternative ingredients may lower production cost without compromising fish *** husbandry practices contribute to a favourable environment for the fish to grow,while interspecific hybridization may be a convenient approach to generate hardier ***,it has been noted that research in *** is relatively scarce in contrast to the closely-related orange-spotted grouper(***),which is used in the present article as a ***,the identified gaps in knowledge between the two species warrant species-specific research in *** to promote fish health and ensure continued success in aquaculture.

关键词： Epinephelus fuscoguttatus Epinephelus coioides Health Immunity Feed Husbandry

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Angiographic characteristics of central serous chorioretinopathy in an Egyptian population

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International Journal of Ophthalmology(English edition) 2013年第3期6卷 342-345页

作者： maha M Shahin Mansoura Faculty of Medicine Mansoura University

· AIM: To describe and analyze the demographic characteristics and to determine the angiographic features of acute central serous chorioretinopathy(CSCR) in an Egyptian population. ·METHODS: A series of consecutive patients presenting with acute idiopathic CSCR to Mansoura Ophthalmology Center Mansoura University who underwent fluorescein angiography (FA) within a 3 -year -period (between January 1, 2007 and December 31, 2009) was retrospectively studied. Patient demographics and angiographic features were studied. Results were compared to those of other Western and Asian populations. ·RESULTS: Fluorescein angiograms of 86 patients were analyzed. 91% were males. The age range of patients was 24 -49 years, with a mean age of (38±6) years. The right eye was the presenting eye in 47% of patients. Eighty seven percent of eyes showed delayed choroidal filling. Thirty -five percent of patients had more than one point of leakage. The macula was the most common site of fluorescein leakage seen in 79% of patients. Peripheral leakage was seen in 14% of patients while peripapillary leakage was seen in 12% of patients. The inkblot leakage pattern was found in 53% of patients. The presenting eye had RPE atrophic changes in 84% of cases. The other eye was assessed in 44 patients (51%). Fifty-five percent of them had signs of RPE atrophic changes. ·CONCLUSION: In the Egyptian population, CSCR is seen at younger age with higher male -to -female ratio and more frequent smokestack leaks than other populations. Despite younger age group, this series of patient showed higher frequency of bilateral and multifocal disease compared to other studies. Roles of psychological stress and choroidal ischemia in pathogenesis of CSCR need further evaluation. ·

关键词： choroidal circulation central serous chorioretinopathy epidemiology fluorescein angiography medical retina

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On Fractional Differential Inclusion for an EpidemicModel via L-Fuzzy Fixed Point Results

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Computer Modeling in Engineering & Sciences 2023年第11期137卷 1937-1956页

作者： maha Noorwali Mohammed Shehu Shagari Department of Mathematics King Abdulaziz UniversityJeddahSaudi Arabia Department of Mathematics Faculty of Physical SciencesAhmadu Bello UniversityZariaNigeria

The real world is filled with uncertainty,vagueness,and *** concepts we meet in everyday life are vague rather than *** real-world situations,if a model requires that conclusions drawn from it have some bearings on reality,then two major problems immediately arise,*** situations are not usually crisp and deterministic;complete descriptions of real systems often require more comprehensive data than human beings could recognize simultaneously,process and *** mathematical tools which require all inferences to be exact,are not always efficient to handle imprecisions in a wide variety of practical *** the latter development,a lot of attention has been paid to examining novel L-fuzzy analogues of conventional functional equations and their various *** this paper,new coincidence point results for single-valued mappings and an L-fuzzy set-valued map in metric spaces are *** novelty and generality,the obtained invariant point notions are compared with some well-known related concepts via non-trivial *** is observed that our principal results subsume and refine some important ones in the corresponding *** an application,one of our results is utilized to discussmore general existence conditions for realizing the solutions of a non-integer order inclusion model for COVID-19.

关键词： Hausdorff metric L-fuzzy set L-fuzzy set-valued map Caputo fractional differential inclusion COVID-19

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