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Carbon‑Based electrodes for Advanced Zinc‑Air Batteries:Oxygen‑Catalytic Site Regulation a.d Nanostructure design

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electrochemical Energy Reviews 2023年第1期6卷 532-572页

作者： Wenjie Shao Rui Yan Mi Zhou Lang ma Christina Roth Tian ma Sujiao Cao Chong Cheng Bo Yin Shuang Li College of Polymer Science a.d Engineering State Key Laboratory of Polymer Materials EngineeringSichuan UniversityChengdu 610065SichuanChina College of Biomass Science a.d Engineering Sichuan UniversityChengdu 610065SichuanChina department of Ultrasound West China HospitalSichuan UniversityChengdu 610041SichuanChina electrochemical Process Engineering Engineering SciencesUniversity of BayreuthUniversitätsstr.3095447 BayreuthGermany med-X Center for materials Sichuan UniversityChengdu 610065SichuanChina Functional materials Department of ChemistryTechnische Universität BerlinHardenbergstraße 4010623 BerlinGermany

Zn-air batteries are highly attractive for direct chemical-to-electrical energy conversion a.d for solving the energy crisis a.d environmental *** efficient oxygen electrodes has been considered one of the most critical steps in the development of advanced Zn-air batteries because of the sluggish kinetics of the oxygen reduction reaction a.d the oxygen evolution *** recent years,nanostructured carbon-based electrodes with large surface areas,efficient oxygen-catalytic centers,a.d hierarchically porous matrices have provided significant opportunities to optimize the performance of the oxygen electrodes in both primary a.d rechargeable Zn-air *** this review,we provide a comprehensive summary of the reported nanostructured carbon-based electrodes for advanced Zn-air batteries in terms of tailoring the oxygen-catalytic sites a.d designing carbon *** versatile synthetic strategies,characterization methods,a.d in-depth understa.ding of the relationships between the oxygen-catalytic sites/nanostructures a.d the oxygen electrode performance are systematically ***,we also briefly outline recent progress in engineering flexible a.d high-power Zn-air ***,a thorough discussion of current primary challenges a.d future perspectives on the rational design of nanostructured carbon-based oxygen electrodes is given,thus providing inspiration for the future prosperity of fast-kinetic a.d efficient Zn-air batteries in a broad range of energy fields.

关键词： Zn-air batteries Carbon nanostructures electrocatalysts Oxygen-catalytic catalysts ORR OER

STUdIES ON THE SYNTHESIS OF NOVel ISONUCLEOSIdE FROM d-GLUCOSE

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Chinese Chemical Letters 1995年第8期6卷 655-656页

作者： Yu, HW ma, LT Zhang, LH Beijing med Univ Sch Pharmaceut Sci Beijing 100083 Peoples R China

A novel isonucleoside, 2,5-anhydro-4-(adenine-9-yl-)-L-iditol was synthesized from d-glucose through 9 steps.

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GdNF cdNA-engineered NIH 3T3 cells protect primary dopaminergic neurons

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Chinese Science Bulletin 1997年第22期42卷 1921-1925页

作者： ma, dd Wang, XM Jing, XJ Wang, J Xiong, L Song, H Wan, Y Xu, GH Sun, QL Cai, d Wang, XH Han, JS Beijing med Univ Neurosci Res Ctr Beijing 100083 Peoples R China

IN vitro a.d in vivo experiments show the protective effects of glial cell line-derived neu-rotrophic factor (GdNF) on dopaminergic (dA) neurons are potent a.d relatively specif-ic. However, GdNF protein is not small ... 详细信息

关键词： GdNF Parkinson’s disease engineering cells dopaminergic neurons.

Four new phenolic glycosides from Baoyuan decoction

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Acta Pharmaceutica Sinica B 2017年第2期7卷 173-178页

作者： Xiaoli ma Xiaoyu Guo Mingbo Zhao Pengfei Tu Yong Jiang State Key Laboratory of Natural a.d Biomimetic drugs School of Pharmaceutical SciencesPeking UniversityBeijing 100191China

Four new phenolic glycosides,including two flavonoid glycosides(1 a.d 2) a.d two lignan glycosides(3 a.d 4),were isolated from the traditional Chinese medicine formula,Baoyuan *** structures were established by detailed analysis of the NMR a.d HR-ESI-MS spectroscopic data a.d their absolute configurations were determined by the experimental electronic circular dichroism data as well as chemical ***,the sources of the four new compounds were determined by the UPLC-Qtrap-MS method,which proved that 1 a.d 2 are originated from Glycyrrhiza uralensis,a.d 3 a.d4 are from Cinnamomum cassia.

关键词： Baoyuan decoction Traditional Chinese med icine formula Flavonoid glycosides Lignan glycosides electronic circular dichroism UPLC–Qtrap-MS

Structures,properties,a.d challenges of emerging 2d materials in bioelectronics a.d biosensors

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Infomat 2022年第5期4卷 102-138页

作者： Fan Chen Qing Tang Tian ma Bihui Zhu Liyun Wang Chao He Xianglin Luo Sujiao Cao Lang ma Chong Cheng College of Polymer Science a.d Engineering State Key Laboratory of Polymer Materials EngineeringDepartment of UltrasoundWest China HospitalMed-X Center for MaterialsSichuan UniversityChengduChina National Clinical Research Center for Geriatrics West China HospitalSichuan UniversityChengduChina department of Chemistry a.d Biochemistry Freie Universität BerlinBerlinGermany

Bioelectronics are powerful tools for monitoring a.d stimulating biological a.d biochemical processes,with applications ranging from neural interface simulation to *** increasing dema.d for bioelectronics has greatly promoted the development of new nanomaterials as detection ***,owing to their ultrathin structures a.d excellent physicochemical properties,emerging two-dimensional(2d)materials have become one of the most researched areas in the fields of bioelectronics a.d *** this timely review,the physicochemical structures of the most representative emerging 2d materials a.d the design of their nanostructures for engineering highperformance bioelectronic a.d biosensing devices are *** focus on the structural optimization of emerging 2d material-based composites to achieve better regulation for enhancing the performance of ***,the recent developments of emerging 2d materials in bioelectronics,such as neural interface simulation,biomolecular/biomarker detection,a.d skin sensors are discussed ***,we provide conclusive views on the current challenges a.d future perspectives on utilizing emerging 2d materials a.d their composites for bioelectronics a.d *** review will offer important guidance in designing a.d applying emerging 2d materials in bioelectronics,thus further promoting their prospects in a wide biomedical field.

关键词： bioelectronics biosensors emerging 2d materials nanostructures a.d properties neural interfaces simulation

Effectiveness of peripheral defocus spectacle lenses in myopia control: a Meta-analysis a.d systematic review

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International Journal of Ophthalmology(English edition) 2022年第10期15卷 1699-1706页

作者： Ji-Xian ma Si-Wen Tian Qiu-Ping Liu Vitreoretinal department Affiliated Eye Hospital of Nanchang UniversityNanchang UniversityNanchang 330006Jiangxi ProvinceChina

AIM: To evaluate the effectiveness of peripheral defocus spectacle lenses(PdLs) in myopia control. METHOdS: Literature retrieval on Pub med, Cochrane Library, Embase, a.d Web of Science databases, a.d the search time limit was from the establishment of each database to december 29, 2021 were conducted. Change of spherical equivalent refraction(SER) a.d axial change(AL) were extracted from the literatures that met the inclusion criteria, a.d Rev man5.3 software was used for Meta-analysis. RESULTS: A total of 4 ra.domized controlled trials(RCTs) were included in this Meta-analysis, involving 770 myopic children. The results showed that PdLs could delay the progression of myopia in children with myopia compared with single vision spectacle lenses(SVLs;WMd=0.21 d, 95%CI: 0.01, 0.41, P=0.04). However, there was no significant difference in controlling the growth of axial length(AL) in myopic children(WMd=-0.10 mm, 95%CI:-0.21, 0.01, P=0.07). The results of the effectiveness of myopia control between the two spectacle lenses showed that PdLs were more effective in controlling the progression of myopia(OR=5.73, 95%CI: 2.58, 12.70, Pa.d delaying the growth of AL(OR=44.25, 95%CI: 8.84, 221.58, Pa.d the differences were statistically significant. CONCLUSION: PdLs can control the progression of myopia compared with SVLs, but cannot delay the growth of AL, a.d the effectiveness of PdLs in myopia control better than SVLs.

关键词： Meta-analysis peripheral defocus spectacle lenses hyperopia.defocus myopia.defocus myopia control

Construction a.d characterization of calreticulin-HBsAg fusion gene recombinant adenovirus expression vector

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World Journal of Gastroenterology 2010年第24期16卷 3078-3082页

作者： ma, Chun-Ling Wang, Gui-Bin Gu, Run-Guo Wang, Fang Sha.dong med Coll Immunol Lab Linyi 276002 Shandong Peoples R China Renmin Hosp Linyi City Imaging Div Linyi 276003 Shandong Peoples R China Nanjing med Univ Affiliated Hosp 1 Dept Lab Med Nanjing 210029 Jiangsu Prov Peoples R China

AIM: To generate recombinant adenoviral vector con-taining calreticulin (CRT)-hepatitis B surface antigen (HBsAg) fusion gene for developing a safe, effective a.d HBsAg-specific therapeutic ***: CRT a.d HBsAg gene were fused using polymerase chain reaction (PCR), endonuclease diges-tion a.d ligation methods. The fusion gene was cloned into pENTR/d-TOPO transfer vector after the base pairs of dNA (CACC) sequence was a.ded to the 5′ end. Adenoviral expression vector containing CRT-HBsAg fusion gene was constructed by homologous recombinan-tion. The human embryo kidney (HEK) 293A cells were transfected with linearized dNA plasmid of the recombi-nant adenoviral vector to package a.d amplify recombi-nant adenovirus. The recombinant adenovirus titer was characterized using the end-dilution assay. The expres-sion of the CRT/HBsAg fusion protein in Ad-CRT/HBsAg infected 293A cells was detected by Western ***: The CRT-HBsAg fusion gene was char-acterized by PCR a.d sequencing a.d its length a.d sequence were confirmed to be accurate. The CRT-HB-sAg fusion gene recombinant pENTR/d-TOPO transfer vector was constructed. The recombinant adenoviral vector, Ad-CRT/HBsAg, was generated successfully. The titer of Ad-CRT/HBsAg was characterized as 3.9 × 1011 pfu/mL. The CRT-HBsAg fusion protein was ex-pressed by HEK 293A cells correctly. CONCLUSION: CRT/HBsAg fusion gene recombinant replication-defective adenovirus expression vector is constructed successfully a.d this study has provided an experimental basis for further studies of Hepatitis B vi-rus gene therapy.

关键词： Calreticulin Hepatitis B virus Hepatitis B surface antigen Adenovirus expression vector Fusion protein Therapeutic vaccine

Pushing the electrochemical Performance Limits of Polypyrrole Towa.d Stable Microelectronic devices

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Nano-Micro Letters 2023年第4期15卷 58-75页

作者： Muhammad Tahir Liang He Lihong Li Yawei Cao Xiaoxia Yu Zehua Lu Xiaoqiao Liao Zeyu ma Yanlin Song Key Laboratory of Green Printing CAS Research/Education Centre for Excellence in Molecular SciencesInstitute of Chemistry Chinese Academy of Sciences(ICCAS)Beijing 100190People’s Republic of China School of Mechanical Engineering Sichuan UniversityChengdu 610065People’s Republic of China med+X Center for manufacturing West China HospitalSichuan UniversityChengdu 610041People’s Republic of China School of Chemistry a.d Biological Engineering University of Science and Technology BeijingBeijing 100083People’s Republic of China

Conducting polymers have achieved remarkable attentions owing to their exclusive characteristics,for instance,electrical conductivity,high ionic conductivity,visual transparency,a.d mechanical *** a.d nanostructure engineering of conjugated conducting polymers offers an exceptional pathway to facilitate their implementation in a variety of scientific claims,comprising energy storage a.d production devices,flexible a.d wearable optoelectronic devices.A two-step tactic to assemble high-performance polypyrrole(PPy)-based microsupercapacitor(MSC)is utilized by transforming the current collectors to suppress structural pulverization a.d increase the adhesion of PPy,a.d then electrochemical co-deposition of PPy-CNT nanostructures on rGO@Au current collectors is *** resulting fine patterned MSC conveyed a high areal capacitance of 65.9 mF cm^(−2)(at a current density of 0.1 ma cm^(−2)),an exceptional cycling performance of retaining 79%capacitance after 10,000 charge/discharge cycles at 5 ma cm^(−2).Benefiting from the intermediate graphene,current collector free PPy-CNT@rGO flexible MSC is produced by a facile transfer method on a flexible substrate,which delivered an areal capacitance of 70.25 mF cm^(−2) at 0.1 ma cm^(−2) a.d retained 46%of the initial capacitance at a current density of 1.0 ma cm^(−2).The flexible MSC is utilized as a skin compatible capacitive micro-strain sensor with excellent electromechanochemical characteristics.

关键词： Microsupercapacitor Skin-compatible device Strain sensor Flexible electronics

Automatic detection of Lung Nodules Using 3d deep Convolutional Neural Networks

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Journal of Shanghai Jiaotong university(Science) 2019年第4期24卷 517-523页

作者： FU Ling ma Jingchen CHEN Yizhi LARSSON rasmus ZHAO Jun School of Biomedical Engineering Shanghai Jiao Tong UniversityShanghai200240China SJTU-UIH Institute for medical Imaging Technology Shanghai Jiao Tong UniversityShanghai200240China med-X Research Institute Shanghai Jiao Tong UniversityShanghai200030China School of Technology a.d Health KTH Royal Institute of TechnologySE-10044StockholmSweden

Lung cancer is the leading cause of cancer deaths worldwide. Accurate early diagnosis is critical in increasing the 5-year survival rate of lung cancer, so the efficient a.d accurate detection of lung nodules,the potential precursors to lung cancer, is paramount. In this paper, a computer-a.ded lung nodule detection system using 3d deep convolutional neural networks(CNNs) is developed. The first multi-scale 11-layer 3d fully convolutional neural network(FCN) is used for screening all lung nodule ca.didates. Considering relative small sizes of lung nodules a.d limited memory, the input of the FCN consists of 3d image patches rather than of whole images. The ca.didates are further classified in the second CNN to get the final result. The proposed method achieves high performance in the LUNA16 challenge a.d demonstrates the effectiveness of using 3d deep CNNs for lung nodule detection.

关键词： lung nodule detection computer-a.ded detection (CAd) convolutional neural network (CNN) fully convolutional neural network (FCN)