Four new phenolic glycosides from Baoyuan decoction

作     者：Xiaoli Ma Xiaoyu Guo Mingbo Zhao Pengfei Tu Yong Jiang 

作者机构：State Key Laboratory of Natural and Biomimetic DrugsSchool of Pharmaceutical SciencesPeking UniversityBeijing 100191China 

出 版 物：《Acta Pharmaceutica Sinica B》 (药学学报（英文版）)

年 卷 期：2017年第7卷第2期

页      面：173-178页

核心收录：

学科分类：1008[医学-中药学(可授医学、理学学位)] 1006[医学-中西医结合] 100602[医学-中西医结合临床] 10[医学] 

基　　金：financially supported by the National Natural Sciences Foundation of China(Nos.81222051 and 81530097) the National Key Technology R&D Program“New Drug Innovation”of China(No.2012ZX09301002-002-002) 

主　　题：Baoyuan decoction Traditional Chinese med icine formula Flavonoid glycosides Lignan glycosides Electronic circular dichroism UPLC–Qtrap-MS 

摘      要：Four new phenolic glycosides,including two flavonoid glycosides(1 and 2) and two lignan glycosides(3 and 4),were isolated from the traditional Chinese medicine formula,Baoyuan *** structures were established by detailed analysis of the NMR and HR-ESI-MS spectroscopic data and their absolute configurations were determined by the experimental electronic circular dichroism data as well as chemical ***,the sources of the four new compounds were determined by the UPLC-Qtrap-MS method,which proved that 1 and 2 are originated from Glycyrrhiza uralensis,and 3 and4 are from Cinnamomum cassia.