Effectiveness of peripheral defocus spectacle lenses in myopia control: a Meta-analysis and systematic review
作者机构：Vitreoretinal DepartmentAffiliated Eye Hospital of Nanchang UniversityNanchang UniversityNanchang 330006Jiangxi ProvinceChina
出 版 物：《International Journal of Ophthalmology(English edition)》 (国际眼科杂志（英文版）)
年 卷 期：2022年第15卷第10期
页 面：1699-1706页
核心收录：
学科分类：1010[医学-医学技术（可授医学、理学学位）] 10[医学]
基 金：Supported by National Natural Science Foundation of China(No.81960177) Jiangxi Provincial Science and Technology Grant(No.20192BAB205049) A research grant from Jiangxi Provincial Health Commission(No.202210723) Postgraduate Innovation Special Fund Project of Jiangxi Province(No.YC2021-S077)
主 题：Meta-analysis peripheral defocus spectacle lenses hyperopia defocus myopia defocus myopia control
摘 要：AIM: To evaluate the effectiveness of peripheral defocus spectacle lenses(PDLs) in myopia control. METHODS: Literature retrieval on Pub Med, Cochrane Library, Embase, and Web of Science databases, and the search time limit was from the establishment of each database to December 29, 2021 were conducted. Change of spherical equivalent refraction(SER) and axial change(AL) were extracted from the literatures that met the inclusion criteria, and Rev Man5.3 software was used for Meta-analysis. RESULTS: A total of 4 randomized controlled trials(RCTs) were included in this Meta-analysis, involving 770 myopic children. The results showed that PDLs could delay the progression of myopia in children with myopia compared with single vision spectacle lenses(SVLs;WMD=0.21 D, 95%CI: 0.01, 0.41, P=0.04). However, there was no significant difference in controlling the growth of axial length(AL) in myopic children(WMD=-0.10 mm, 95%CI:-0.21, 0.01, P=0.07). The results of the effectiveness of myopia control between the two spectacle lenses showed that PDLs were more effective in controlling the progression of myopia(OR=5.73, 95%CI: 2.58, 12.70, P0.001) and delaying the growth of AL(OR=44.25, 95%CI: 8.84, 221.58, P0.001) than SVLs, and the differences were statistically significant. CONCLUSION: PDLs can control the progression of myopia compared with SVLs, but cannot delay the growth of AL, and the effectiveness of PDLs in myopia control better than SVLs.
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