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Intensified East Asian summer monsoon and associated precipitation mode shift under the 1.5 ℃ global warming target

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Advances in Climate Change Research 2018年第2期9卷 102-111页

作者： WANG Tao miao jia-peng SUN jian-Qi FU Yuan-Hai Nansen-Zhu International Research Center Institute of Atmospheric Physics Chinese Academy of Sciences Beijing 100029 China Collaborative Innovation Center on Forecast and Evaluation of Meteorological Disasters Nanjing University of Information Science and Technology Nanjing 210044 China University of Chinese Academy of Sciences Beijing 100049 China Climate Change Research Center Chinese Academy of Sciences Beijing 100029 China

In this study, the East Asian summer climate changes under the 1.5 ℃ global warming （1.5 GW） target in 30 simulations derived from 15 coupled models within the Coupled Model Intercomparison Program phase 5 （CMIP5） are examined. Compared with the current summer climate （1975-2005）, both surface air temperature and precipitation increase significantly over the East Asian continent during the 1.5 GW period （average period 2021-2051）. In northeastern China this is particularly pronounced with regional averaged precipitation increases of more than 7.2%, which is greater than that for the whole East Asian continent （approximately 4.2%）. Due to stronger enhancement of precipitation north of 40°N, the leading empirical orthogonal function （EOF） mode of summer precipitation over the East Asian continent changes from tripolar-like mode to dipole mode. As there is stronger surface warming over the East Asian continent than that over surrounding ocean, the land-sea thermal contrast is enhanced during the 1.5 GW period. As a result, the monsoon circulation in the lower troposphere is significantly strengthened, which causes the increased summer precipitation over the East Asian continent. In addition, larger interannual variabilities of East Asian summer monsoon circulation and associated precipitation are also suggested for the 1.5 GW period.

关键词： East Asian summer monsoon Precipitation 1.5 ℃ global warming target CMIP5

Mid-summer surface air temperature and its internal variability over China at 1.5℃ and 2℃ global warming

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Advances in Climate Change Research 2020年第3期11卷 185-197页

作者： YIN Shu-Yue WANG Tao HUA Wei miao jia-peng GAO Yong-Qi FU Yuan-Hai Daniela MATEI Evangelos TYRLIS CHEN Dong Joint Laboratory for Climate and Environmental Change Chengdu University of Information TechnologyChengdu610225China Nansen-Zhu International Research Centre Institute of Atmospheric PhysicsChinese Academy of SciencesBeijing100029China Climate Change Research Center Chinese Academy of SciencesBeijing100029China Nansen Environmental and Remote Sensing Center Bjerknes Center for Climate ResearchBergen5006Norway Max Planck Institute for Meteorology Hamburg20146Germany

Recently,extremely hot summers occurred frequently across China,and the mean mid-summer surface air temperature(SAT)continuously broke the records of the past decades,causing huge social and economic *** global warming accelerates,these extremely hot summers will undoubtedly occur more ***,the issue of what will happen to the mid-summer SAT over China in the near future remains ***,we investigate the changes of mid-summer SAT and related internal variabilities over China at 1.5℃ and 2℃ global warming above preindustrial level by using the MPI-ESM Grand Ensemble *** results indicate that compared to the present-day(1986–2005),national averaged mid-summer SAT will increase by 1.1℃ and 2.0℃,in 1.5℃ and 2℃ warming scenarios *** means that the mid-summer SAT is projected to increase by 0.9℃ due to an additional 0.5℃ global warming,which is higher than the annual value(0.8℃)and almost two times the global warming ***,in the two warming targets,the increase in mid-summer SAT will be more enhanced over the northwestern part of *** addition,the extremely high monthly SAT would increase nationwide due to an additional 0.5℃ in global *** all areas,the Qinghai and Xinjiang provinces would experience the strongest increase in extremely high monthly *** is important to find that,from 1.5℃ to 2℃ global warming,changes of the internal variability of the mid-summer SAT differs across *** would decrease over some parts of western Northwest China,North China,Northeast China and the Tibetan ***,it would significantly increase over Qinghai,Sichuan,and northern parts of Inner *** a result,at 2℃ global warming,the increase of extreme SAT in Qinghai is caused by the synergistic effect of stronger warming rate and larger internal ***,the increase in Xinjiang province is mainly caused by the stronger local *** analysis suggests that we can effect

关键词： Mid-summer SAT Internal variability China 1.5℃global warming 2℃global warming

RGS4 promotes the progression of gastric cancer through the focal adhesion kinase/phosphatidyl-inositol-3-kinase/protein kinase B pathway and epithelial-mesenchymal transition

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World Journal of Gastroenterology 2025年第2期31卷 113-127页

作者： peng-Yu Chen Pei-Yao Wang Bang Liu Yang-Pu jia Zhao-Xiong Zhang Xin Liu Dao-Han Wang Yong-jia Yan Wei-Hua Fu Feng Zhu Department of General Surgery Tianjin Medical University General HospitalTianjin Medical UniversityTianjin 300052China Department of General Surgery Jincheng People’s HospitalJincheng 048000Shanxi ProvinceChina

BACKGROUND Regulator of G protein signaling(RGS)proteins participate in tumor formation and metastasis by acting on theα-subunit of heterotrimeric G *** speci-fic effect of RGS,particularly RGS4,on the progression of gastric cancer(GC)is not yet *** To explore the role and underlying mechanisms of action of RGS4 in GC *** The prognostic significance of RGS4 in GC was analyzed using bioinformatics based public databases and verified by immunohistochemistry and quantitative polymerase chain reaction in 90 patients with *** assays were employed to assess the carcinogenic impact of RGS4,and the mechanism of its possible influence was detected by western blot analysis.A nude mouse xenograft model was established to study the effects of RGS4 on GC growth in *** RGS4 was highly expressed in GC tissues compared with matched adjacent normal *** RGS4 expression was correlated with increased tumor-node-metastasis stage,increased tumor grade as well as poorer overall survival in patients with *** experiments demonstrated that RGS4 knockdown suppressed GC cell proliferation,migration and ***,xenograft experiments confirmed that RGS4 silencing significantly inhibited tumor ***,RGS4 knockdown resulted in reduced phosphorylation levels of focal adhesion kinase,phosphatidyl-inositol-3-kinase,and protein kinase B,decreased vimentin and N-cadherin,and elevated *** High RGS4 expression in GC indicates a worse prognosis and RGS4 is a prognostic ***4 influences tumor progression via the focal adhesion kinase/phosphatidyl-inositol-3-kinase/protein kinase B pathway and epithelial-mesenchymal transition.

关键词： Gastric cancer Prognosis Regulator of G protein signaling 4 Focal adhesion kinase Epithelial-mesenchymal transition

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铁炭微电解法去除磺胺类抗生素的研究

中国给水排水 2016年第23期32卷 96-100页

作者：缪佳付阳彭博宇沈峥周雪飞张亚雷浙江工业大学建筑工程学院浙江杭州310014 同济大学污染控制与资源化研究国家重点实验室上海200092 同济大学国家设施农业工程技术研究中心上海200092

近年来,由于抗生素的过量使用和不适当排放引起水体污染问题,使人们对抗生素有效降解方法的探索也日益增多。选取了三种常见磺胺类抗生素,并以其中一种磺胺甲基嘧啶作为主要研究对象,考察了铁炭微电解法对磺胺类抗生素的去除效果及反应... 详细信息

近年来,由于抗生素的过量使用和不适当排放引起水体污染问题,使人们对抗生素有效降解方法的探索也日益增多。选取了三种常见磺胺类抗生素,并以其中一种磺胺甲基嘧啶作为主要研究对象,考察了铁炭微电解法对磺胺类抗生素的去除效果及反应过程。首先,通过单因素试验得到了最佳反应条件,即初始pH值为2、铁炭填料填装量为1 g/m L、温度为25℃和曝气量为60 L/h,在该条件下反应8 h,对磺胺甲基嘧啶的去除率可达82.9%,对TOC的去除率达45.2%。其次,通过测定反应中TOC、TN、NO_3^-、SO_4^(2-)、Fe^(2+)、Fe^(3+)的浓度变化趋势,揭示了铁炭微电解法降解磺胺类抗生素的反应途径,即抗生素中的S—N键断裂释放出S、N原子,再经过一系列的氧化还原作用得到进一步去除。

关键词：磺胺类抗生素铁炭微电解 TOC

Porous Organic Cage‑Based Quasi‑Solid‑State Electrolyte with Cavity‑Induced Anion‑Trapping Effect for Long‑Life Lithium Metal Batteries

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Nano-Micro Letters 2025年第2期17卷 376-386页

作者： Wei-Min Qin Zhongliang Li Wen‑Xia Su jia‑Min Hu Hanqin Zou Zhixuan Wu Zhiqin Ruan Yue‑peng Cai Kang Li Qifeng Zheng School of Chemistry South China Normal UniversityGuangzhou 510006People’s Republic of China Key Laboratory of Functional Metal‑Organic Compounds of Hunan Province College of Chemistry and Material ScienceHengyang Normal UniversityHengyang 421008People’s Republic of China Guangzhou Key Laboratory of Energy Conversion and Energy Storage Materials Guangzhou 510006People’s Republic of China

Porous organic cages(POCs)with permanent porosity and excellent host–guest property hold great potentials in regulating ion transport behavior,yet their feasibility as solid-state electrolytes has never been testified in a practical ***,we design and fabricate a quasi-solid-state electrolyte(QSSE)based on a POC to enable the stable operation of Li-metal batteries(LMBs).Benefiting from the ordered channels and cavity-induced anion-trapping effect of POC,the resulting POC-based QSSE exhibits a high Li+transference number of 0.67 and a high ionic conductivity of 1.25×10^(−4) S cm^(−1) with a low activation energy of 0.17 *** allow for homogeneous Li deposition and highly reversible Li plating/stripping for over 2000 *** a proof of concept,the LMB assembled with POC-based QSSE demonstrates extremely stable cycling performance with 85%capacity retention after 1000 ***,our work demonstrates the practical applicability of POC as SSEs for LMBs and could be extended to other energy-storage systems,such as Na and K batteries.

关键词： Porous organic cage Cavity-induced anion-trapping Quasi-solid-state electrolyte Homogeneous Li+flux Lithium metal battery

Axial segregation characteristics and size-induced flow behavior of particles in a novel rotary drum with curved sidewalls

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Particuology 2024年第4期87卷 1-19页

作者： Qiuhua miao Wenchang Zhu Yudong Cao peng Huang Chaobin Hu Minping jia School of Mechanical Engineering Southeast UniversityNanjing211189China jiangsu Key Laboratory for Elevator Inteligent Safety Changshu215500China

Particle mixing and segregation are common phenomena in rotary drums,which are challenging to be controlled and driven artificially in powder *** this work,the discrete element method(DEM)was applied to construct the novel rotary drum composed of different shaped curved *** varying the operation parameters of particle and sidewall shapes as well as the length-to-diameter(L/D)ratio of drums,the axial mixing and segregation processes of binary size-induced particles were *** results show that the axial flow velocity of the particle mixtures is noticeably weakened once the particle angularity increases,making the non-spherical particles to mix better in rotary drums compared to the spherical ***,in the short drums with size-induced spherical particles,the axial segregation characteristics are significantly enhanced by the convex sidewalls while suppressed by the concave ***,for size-induced non-spherical particles,the axial segregation structure can be present in rotary drums with plane and concave sidewalls while not in drums with convex ***,the axial segregation band structure of spherical particles eventually increases proportionally with the increased drum L/D *** contrast,the non-spherical particles cannot form obvious multi-proportional segregation bands.

关键词： Axial flow behaviors Size-induced particles Curved sidewalls Non-spherical particles Rotary drum

Determining the geographic origin of the brown planthopper, Nilaparvata lugens, using trace element content

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Insect Science 2012年第1期19卷 21-29页

作者： Qi peng Qi-Yi Tang jia-Lun Wu Qing-Ling miao jia-An Cheng State Key Laboratory of Rice Biology Institute of Insect SciencesZhejiang UniversityHangzhouChina

bstract A chemometric study using pattern recognition technology was carried out to characterize the geographic origins of the brown planthopper, Nilaparvata lugens. The concentrations of 23 trace elements （Mn, Mo, Cd, Ce, V, Th, Cs, Be, T1, Fe, Nd, Pr, Se, Tm, Lu, Eu, Ho, Br, Dy, Gd, U, Sm and Er） in 53 samples from seven regions in southern China were determined using inductively coupled plasma mass spectrometry. The data obtained were successively evaluated using a multivariate statistical approach, namely, linear discriminant analysis, which allowed classification and discrimination of the N. lugens samples from Fuqing, Shaoguan, Hepu, Yongfu, Hengnan, Wan-an and Yongkang with high accuracy and a clear separation among the seven regions. The results show that pattern identification on the basis of trace elements in the bodies ofN. lugens is feasible for determining the geographic origins of individuals.

关键词： brown planthopper discriminant analysis forecasting geographic origin trace element

Realgar(α-As_(4)S_(4))Treats Myelodysplastic Syndromes through Reducing DNA Hypermethylation

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Chinese Journal of Integrative Medicine 2022年第3期28卷 281-288页

作者： ZHANG miao ZHANG jia-yi SUN Ming-qian LU peng LIU jian-xun Research Center Xiyuan HospitalChina Academy of Chinese Medical Sciences and Beijing Key Lab of Traditional Chinese Medicine PharmacologyBeijing(100091)China Education Sector Xiyuan HospitalChina Academy ofChinese Medical SciencesBeijing(100091)China MedicalAdministration Division Xiyuan HospitalChina Academy ofChinese Medical SciencesBeijing(100091)China

DNA hypermethylation is an epigenetic modification that plays a critical role in the oncogenesis of myelodysplastic syndromes(MDS).Aberrant DNA methylation represses the transcription of promotors of tumor suppressor genes,inducing gene ***(α-As_(4)S_(4))is a traditional medicine used for the treatment of various diseases in the ancient *** was reported to have efficacy for acute promyelocytic leukemia(APL).It has been demonstrated that realgar could efficiently reduce DNA hypermethylation of *** review discusses the mechanisms of realgar on inhibiting DNA hypermethylation of MDS,as well as the species and metabolisms of arsenic in vivo.

关键词： myelodysplastic syndromes DNA hypermethylation realgar arsenic review

Nano-scale pore distribution characterisation of coal using small angle X-ray scattering

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Particuology 2023年第10期81卷 73-85页

作者： peng jia Jinzhang jia Sadegh Nadimi College of Safety Science and Engineering Liaoning Technical UniversityFuxinLiaoning123000China School of Engineering Newcastle UniversityNE17RUUK

In the process of coal seam fracturing with liquid nitrogen(LN_(2)),the change of coal pore structure has an important influence on the efficiency of coalbed methane(CBM)*** nano-scale pore size distribution(PSD)in coal particles before and after freezing with LN_(2) are experimentally studied in this *** samples are collected from four coal mines,where coal and gas outburst accidents have *** angle X-ray scattering technology(SAXS)and scanning electron microscopy(SEM)are used to study the pore structure changes of coal samples quantitatively and *** is found that the scattering intensity of coal samples increases after *** PSD of all samples significantly changes in the range of 0.8–7 nm,showing new pore spaces in 0.8–4 nm and fewer pores in the 4–7 nm *** the pore fractal dimension and the radius of gyration of coal samples increase after freezing and are mainly affected by the changes in pores and the anisotropy of the coal *** expansion and pore connections are observed in the surface structure of the coal sample using *** study provides a better understanding of the nano-scale mechanism of coal seam fracturing with LN_(2) for the prevention of coal and gas outbursts.

关键词： Coalbed methane Small angle X-ray scattering LN2 freezing Pore size distribution(PSD) Particle characterisation Fractal dimension