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Cumulative Risk Assessment of Exposure to Heavy Metals through Aquatic Products in China

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Biomedical and Environmental Sciences 2021年第8期34卷 606-615页

作者： WANG Hui MAO Wei Feng JIANG Ding Guo LIU Si Jie ZHANG Lei NHC Key Laboratory of Food Safety Risk Assessment Chinese Academy of Medical Science Research UnitChina National Center for Food Safety Risk AssessmentBeijing 100022China Department of Physical and Chemical Test Jilin Provincial Center for Disease Control and PreventionChangchun 130062JilinChina

Objective This study aimed to assess the risk of cumulative exposure to Pb,Cd,Hg,and iAs through aquatic products consumed by Chinese people.Methods Heavy metal concentration data were obtained from the national food contamination monitoring program during 2013–2017.Consumption data were derived from the China National Food Consumption Survey in 2014 and the relative potency factor(RPF)method was used to estimate cumulative exposure for neurotoxicity and nephrotoxicity.Results The results demonstrated that the cumulative exposure based on neurotoxicity was below the lower confidence limit on benchmark doses of lead(BMDL01)for nephrotoxicity and the cumulative exposures were all lower than the provisional tolerable monthly intake(PTMI)of Cd.However,the margin of exposure values(MOEs)of the cumulative exposures for neurotoxicity in the 2–6 year-old group was close to 1 and the cumulative exposure level for nephrotoxicity accounted for 90.21%of the PTMI.Conclusion The cumulative exposures of the 2–6 year-old group to the four heavy metals did not reach(but came close to)the corresponding safety threshold for both neurotoxicity and nephrotoxicity.Given that there are still other food sources of these four heavy metals,it is necessary to more closely study their cumulative health effects.

关键词： Arsenic Lead Cadmium Mercury Aquatic products Heavy metals

Social-Aware Cooperation Among Mobile Terminals for Wireless Downlink Transmission

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China Communications 2015年第9期12卷 1-10页

作者： mao Hongliang feng wei Ge Ning Tsinghua National Lab for Information Science and Technology Tsinghua University

This paper investigates the social-aware cooperation(SAC) among mobile terminals(MTs), motivated by the fact that modern smart devices have much improved context awareness. Aware of the social ties, the cooperative network contains two layers of property: social and physical. In order to observe how the social awareness benefit the cooperation performance, we first formulate the social ties between MTs into parameters that can describe the cooperative behaviors by taking the mobility feature into account, defined as the conviction-approval-suspicion(CAS) model. Limited by the processing capability, partner selection is of great practical significance. To this end, the social-aware partner selection strategy is analyzed, and a significant superiority is observed compared to social-unaware selection. By analyzing the cooperative throughput, an explicit relationship between the degrees-of-freedom gain and the social-physical property is finally derived. Simulation results validate the theoretical analysis.

关键词：社会意识移动终端链路传输合作网络无线合作伙伴物质属性环境意识

Orientation gradient on surface of non-oriented electrical steel annealed by γ → α transformation

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Journal of Iron and Steel Research(International) 2020年第1期27卷 88-95页

作者： Jin-hua Wang Ping Yang wei-min mao feng-e Cui School of Materials Science and Engineering University of Science and Technology BeijingBeijing 100083China

The microstructures and textures of the non-oriented electrical steel sheets under various annealing conditions were investigated.The orientation gradient in the interior of grains appeared on the surface of steel sheets after α→γ→α transformation in various atmospheres.The orientation gradient that appeared on the surface was inherited into the center of the steel sheet in H2 atmosphere,while that appeared only in the grains of the surface layer during γ→α transformation with N2 atmosphere.The thin oxide scale was generated in various atmospheres containing traces of O2 and H2O.The formation mechanism of orientation gradient is related to the thermal stress caused by the difference of thermal expansion coefficients between the oxide scale and the thin ferrite on the surface.The combined effect of phase transformation stress and thermal stress caused the plastic deformation of the thin ferrite grains on the surface in the initial stage of γ→α transformation,and then the orientations of the thin ferrite grains gradually rotated and caused the orientation gradient in the interior of grains.

关键词： Electrical steel Texture Phase transformation-Thermal stress Oxide scale

Stochastic averaging of quasi partially integrable Hamiltonian systems under fractional Gaussian noise

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2017年第9期18卷 704-717页

作者： Qiang-feng LU mao-lin DENG wei-qiu ZHU Department of Mechanics Zhefiang University Hangzhou 310077 China State Key Laboratory of Fluid Power and Mechatronic Systems Zhejiang University Hangzhou 310027 China Key Laboratory of Soft Machines and Smart Devices of Zhejiang Province Zhejiang University Hangzhou 310027 China

A stochastic averaging method for predicting the response of quasi partially integrable and non-resonant Hamiltoniansystems to fractional Gaussian noise （fGla） with the Hurst index 1/2〈H〈l is proposed. The averaged stochastic differential equa-tions （SDEs） for the first integrals of the associated Hamiltonian system are derived. The dimension of averaged SDEs is less thanthat of the original system. The stationary probability density and statistics of the original system are obtained approximately fromsolving the averaged SDEs numerically. Two systems are worked out to illustrate the proposed stochastic averaging method. It isshown that the results obtained by using the proposed stochastic averaging method and those from digital simulation of originalsystem agree well, and the computational time for the former results is less than that for the latter ones.

关键词： Fractional Brownian motion (fBm) Fractional Gaussian noise (fGn) Quasi partially integrable Hamiltonian system Stochastic averaging method Stationary response

Radio frequency interference mitigation using pseudoinverse learning autoencoders

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Research in Astronomy and Astrophysics 2020年第8期20卷 121-128页

作者： Hong-feng Wang mao Yuan Qian Yin Ping Guo wei-wei Zhu Di Li Si-Bo feng Image Processing and Pattern Recognition Laboratory School of Artificial IntelligenceBeijing Normal UniversityBeijing 100875China CAS Key Laboratory of FAST National Astronomical ObservatoriesChinese Academy of SciencesBeijing 100101China School of Information Management Dezhou UniversityDezhou 253023China Image Processing and Pattern Recognition Laboratory School of System ScienceBeijing Normal UniversityBeijing 100875China Institute for Astronomical Science Dezhou UniversityDezhou 253023China University of Chinese Academy of Sciences Beijing 100049China Hanvon Technology Co. LtdBeijing 100193China NAOC-UKZN Computational Astrophysics Centre University of KwaZulu-NatalDurban 4000South Africa

Radio frequency interference(RFI)is an important challenge in radio astronomy.RFI comes from various sources and increasingly impacts astronomical observation as telescopes become more sensitive.In this study,we propose a fast and effective method for removing RFI in pulsar data.We use pseudo-inverse learning to train a single hidden layer auto-encoder(AE).We demonstrate that the AE can quickly learn the RFI signatures and then remove them from fast-sampled spectra,leaving real pulsar signals.This method has the advantage over traditional threshold-based filter method in that it does not completely remove contaminated channels,which could also contain useful astronomical information.

关键词： pulsars:general methods:numerical methods:data analysis

Modelling and fabrication of wide temperature range Al_(0.24)Ga_(0.76)As/GaAs Hall magnetic sensors

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Journal of Semiconductors 2022年第3期43卷 87-93页

作者： Hua Fan Huichao Yue Jiangmin mao Ting Peng Siming Zuo Quanyuan feng Qi wei Hadi Heidari State Key Laboratory of Electronic Thin Films and Integrated Devices University of Electronic Science and Technology of ChinaChengdu 610054China Chengdu HiWafer Semiconductor Co. Ltd.Chengdu 610225China James Watt School of Engineering University of GlasgowG128QQGlasgowUK Southwest Jiaotong University Chengdu 611756China Department of Precision Instrument Tsinghua UniversityBeijing 100084China Institute of Electronic and Information Engineering of UESTC in Guangdong University of Electronic Science and Technology of ChinaDongguan 523878China

Silicon Hall-effect sensors have been widely used in industry and research fields due to their straightforward fabrication process and CMOS compatibility.However,as their material property limitations,technicians usually implement complex CMOS circuits to improve the sensors’performance including temperature drift and offset compensation for fitting tough situation,but it is no doubt that it increases the design complexity and the sensor area.Gallium arsenide(GaAs)is a superior material of Hall-effect device because of its large mobility and stable temperature characteristics.Concerning there is no specified modelling of GaAs Hall-effect device,this paper investigated its modelling by using finite element method(FEM)software Silvaco TCAD®to help and guide GaAs Hall-effect device fabrication.The modeled sensor has been fabricated and its experimental results are in agreement with the simulation results.Comparing to our previous silicon Hall-effect sensor,the GaAs Hall-effect sensor demonstrates potential and reliable benchmark for the future Hall magnetic sensor developments.

关键词： Hall-effect sensors GaAs Hall sensor GaAs semiconductor device

Endemic medicinal plant distribution correlated with stable climate,precipitation,and cultural diversity

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Plant Diversity 2023年第4期45卷 479-484页

作者： Gang feng Ying-Jie Xiong Hua-Yu wei Yao Li Ling-feng mao Ministry of Education Key Laboratory of Ecology and Resource Use of the Mongolian Plateau&Inner Mongolia Key Laboratory of Grassland Ecology School of Ecology and EnvironmentInner Mongolia UniversityHohhotChina Co-Innovation Center for Sustainable Forestry in Southern China College of Biology and the EnvironmentNanjing Forestry UniversityNanjingChina

Medicinal plants provide crucial ecosystem services,especially in developing countries such as China,which harbors diverse endemic medicinal plant species with substantial cultural and economic value.Accordingly,understanding the patterns and drivers of medicinal plant distribution is critical.However,few studies have investigated the patterns and drivers of endemic medicinal plants distribution in China.Here,we linked endemic medicinal plants distribution with possible explanatory variables,i.e.,paleoclimate change,contemporary climate,altitudinal range and ethnic minority human population size at the prefecture city level in China.Our results show that endemic medicinal plants are concentrated in southern China,especially in southwestern China.Notably,both endemic medicinal plant species richness and the ratio of endemic medicinal plant species richness are negatively associated with glacialinterglacial anomaly in temperature,and positively associated with contemporary precipitation and altitudinal range.In addition,we found that endemic medicinal plant species richness is positively associated with ethnic minority population sizes as well as its ratio to the overall population size.These findings suggest that the distribution of endemic medicinal plants is determined by multiple drivers.Furthermore,our findings stress that dramatic future climate changes and massive anthropogenic activities in southern China pose great challenges to the conservation of China's endemic medicinal plants.

关键词： Altitudinal range Cultural diversity Endemic medicinal plant Glacial-interglacial climate change Precipitation Spatial distribution

Rapid construction of a whole-genome mutant library by combining haploid stem cells and inducible self-inactivating PiggyBac transposon

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Protein & Cell 2020年第6期11卷 452-457页

作者： Junjie mao Kai Xu Jiabao Han Guihai feng Ying Zhang wei Li State Key Laboratory of Stem Cell and Reproductive Biology Institute of ZoologyChinese Academy of SciencesBeijing 100101China Institute for Stem Cell and Regeneration Chinese Academy of SciencesBeijing 100101China University of Chinese Academy of Sciences Beijing 100049China

Dear Editor,Genome-scale screening is a powerful method used to explore phenotypes that are of interest,and numerous screening systems have been built for functional sites identification.Classical genetic screening in eukaryotes has been performed using chemical mutagens(Chen et al.,2000),transposon mediated gene trapping(Dupuy et al.,2005),and CRISPR-Cas9 system(Wang et al.,2014).

关键词： PiggyBac inducible inactivating

Incidence and treatment of brain metastasis in patients with esophageal carcinoma

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World Journal of Gastroenterology 2015年第19期21卷 5805-5812页

作者： wei feng Peng Zhang Xiao Zheng Ming Chen wei-Min mao Department of Radiation Oncology Zhejiang Key Laboratory of Diagnosis and Treatment Technology on Thoracic Oncology (Lung and Esophagus) Zhejiang Key Laboratory of Radiation Oncology Zhejiang Cancer Hospital

Brain metastasis from esophageal carcinoma(BMEC) is very rare, but its incidence has increased in the United States, Japan, China and other counties. Reports on BMEC have largely been focused on examining whether adjuvant therapy for esophageal cancer influences the survival duration of BMEC patients and on the imaging characteristics of BMEC determined using new medical equipment. The difference between different pathological types of esophageal cancer, especially adenocarcinoma and squamous cell carcinoma, is one important factor used to assess the influence of BMEC. Adjuvant therapy, including radiotherapy and chemotherapy, for esophageal cancer with different characteristics in different countries may affect BMEC treatment outcomes. The degree of popularization of advanced medical equipment is a major concern related to the prevalence of BMEC. Furthermore,targeted BMEC treatment is under development in developed countries. In this article, we reviewed the debate surrounding BMEC and analyzed BMEC studies from different perspectives.

关键词： Brain metastasis Esophageal carcinoma Magnetic resonance imagin Computed tomography