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论当代西方戏剧中的“在场”

外国文学研究 2010年第5期32卷 145-153页

作者：孙冬 man-Wah luke chan 南京财经大学外国语学院麦克马斯特大学加拿大麦克马斯特大学

"在场"是戏剧的本质特征并和戏剧史上各种潮流变迁息息相关。现代主义的戏剧传统推崇文本的叙事建构,贬抑戏剧性和舞台形象。"在场"被界定为通过模拟的手段将不在场的"现实"展现出来,使观众仿佛置身于事件发生的现场。20世纪60年代,受... 详细信息

"在场"是戏剧的本质特征并和戏剧史上各种潮流变迁息息相关。现代主义的戏剧传统推崇文本的叙事建构,贬抑戏剧性和舞台形象。"在场"被界定为通过模拟的手段将不在场的"现实"展现出来,使观众仿佛置身于事件发生的现场。20世纪60年代,受阿尔托思想的影响,戏剧重新张扬演员的身体及视听意象,尝试自发性表演以及观众和戏剧之间随机互动。"在场"成为演员在戏剧当下自发地呈现内心精神以及戏剧和观众在不断变化的空间和无预先设定的条件下真实地、共同地创造一种不可重复的戏剧经验。然而,德里达和鲍德里亚关于"延异"和"拟像"的理论否定了纯粹的自发性和即时性,任何"在场"都无法逃脱"再现"的命运。进入后现代之后的当代戏剧将严肃议题、传统的结构、后现代元素和先锋戏剧的舞台能量混合制成一种新型的"现实主义"。戏剧糅合这种形式的"在场"并在呈现在场的同时,又揭示在场的幻觉。

关键词：在场再现残酷戏剧解构

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基本面因素与人民币均衡汇率

统计研究 2012年第5期29卷 51-57页

作者：李泽广 man-Wah luke chan 麦克玛斯特大学商学院南开大学经济学院加拿大麦克玛斯特大学DeGroote商学院

测算方法的差异使得对人民币均衡汇率水平的不同研究的测度结果大相径庭。本文借鉴新近研究,引入生产率和国外净资产变量,采用经常账户缺口法、基本行为均衡方法的误差修正模型和ML-ARCH模型测度了人民币汇率的均衡区间;并探讨了决定均... 详细信息

测算方法的差异使得对人民币均衡汇率水平的不同研究的测度结果大相径庭。本文借鉴新近研究,引入生产率和国外净资产变量,采用经常账户缺口法、基本行为均衡方法的误差修正模型和ML-ARCH模型测度了人民币汇率的均衡区间;并探讨了决定均衡汇率变化的基本面因素。结果证实人民币被低估的水平并不十分显著,生产率的提升、贸易条件变化和增长导向的经济发展模式和外汇储备是决定均衡汇率变化趋势的关键基本面因素;均衡汇率变化的估值效应能够显著影响国外净资产水平。

关键词：基本均衡汇率经常账户缺口法 Bootstrap估计

Voltage-gated K^+channels promote BT-474 breast cancer cell migration

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Chinese Journal of Cancer Research 2018年第6期30卷 613-622页

作者： Louis WC Chow Ka-Shun Cheng kar-Lok Wong Yuk-man Leung State Key Laboratory of Quality Research in Chinese Medicines Macao University of Science and TechnologyTaipaMacao 999078China UNIMED Medical Institute Hong Kong 999077China Organisation for Oncology and Translational Research Hong Kong 999077China Department of Anesthesiology China Medical University HospitalTaiehung 40447TaiwanChina Department of Anesthesiology the Qingdao University Yuhuangding HospitalYantai 264000China Department of Physiology China Medical UniversityTaichung 40402TaiwanChina

Objective: A variety of ion channels have been implicated in breast cancer proliferation and *** K+(Kv) channels not only cause repolarization in excitable cells,but are also involved in multiple cellular functions in non-excitable *** this study we investigated the role of Kv channels in migration of BT474 breast cancer ***: Transwell technique was used to separate migratory cells from non-migratory ones and these two groups of cells were subject to electrophysiological examinations and microfluorimetric measurements for cytosolic *** migration was examined in the absence or presence of Kv channel ***: When compared with non-migratory cells,migratory cells had much higher Kv current densities,but rather unexpectedly,more depolarized membrane potential and reduced *** transcriptasepolymerase chain reaction(RT-PCR) analysis revealed the presence of Kv1.1,Kv1.3,Kv1.5,Kv2.1,Kv3.3,Kv3.4 and Kv4.3 *** migration was markedly inhibited by tetraethylammonium(TEA),a delayed rectifier Kv channel blocker,but not by 4-aminopyridine,an A-type Kv channel ***: Taken together,our results show that increased Kv channel expression played a role in BT474 cell migration,and Kv channels could be considered as biomarkers or potential therapeutic targets for breast cancer *** mechanism(s) by which Kv channels enhanced migration appeared unrelated to membrane hyperpolarization and Cainflux.

关键词： Breast cancer Kv channels migration biomarkers

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债务期限与投资决策互动关系中的非线性机制

当代经济研究 2014年第7期 70-75页

作者：孙弘博李泽广 man-Wah luke chan 南开大学经济学院天津300071 加拿大麦克玛斯特大学商学院

代理成本理论是解读债务期限与投资关系的关键视角,投资不足与投资过度都是代理成本问题的表现形式。西方投资理论认为,短期债务可以有效降低代理成本,长期债务能够更好地缓解融资约束问题。然而,在较为复杂的代理成本机制主导下,债务... 详细信息

代理成本理论是解读债务期限与投资关系的关键视角,投资不足与投资过度都是代理成本问题的表现形式。西方投资理论认为,短期债务可以有效降低代理成本,长期债务能够更好地缓解融资约束问题。然而,在较为复杂的代理成本机制主导下,债务期限对投资的影响呈现出非线性作用机制,不同投资区间债务期限选择会直接影响代理成本高低,进而影响投资效率。基于我国上市公司的经验数据可以发现,不同投资规模区间债务期限与投资遵循非线性关系的特征事实。在融资约束和制度不完备的背景下,上市公司应注重健全并完善公司治理机制,降低代理成本,方能优化债务期限选择,实现投资决策与外部金融环境间的良好互动。

关键词：制度环境代理成本债务期限投资

Metabolic syndrome and benign prostatic hyperplasia:An update

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Asian Journal of Urology 2017年第3期4卷 164-173页

作者： Ho-Yin Ngai kar-Kei Steffi Yuen Chi-man Ng Cheung-Hing Cheng Sau-Kwan Peggy Chu Division of Urology Department of SurgeryQueen Elizabeth HospitalHong KongChina Division of Urology Department of SurgeryTuen Mun HospitalHong KongChina

Metabolic syndrome(MetS)is a cluster of metabolic abnormalities related to central adiposity and insulin *** importance is increasingly recognized as it associates with increased risks of metabolic and cardiovascular *** metabolic aberrations of MetS may lead to development of benign prostatic hyperplasia(BPH)and lower urinary tract symptoms(LUTS)in men.A 26.5%-55.6% prevalence of MetS in men with LUTS was reported in worldwide *** the exact biological pathway is not clear yet,insulin resistance,increased visceral adiposity,sex hormone alterations and cellular inflammatory reactions played significant roles in the related pathophysiological *** should recognize the cardiovascular and metabolic impacts of MetS in men with LUTS,early risk factors optimization and use of appropriate medical therapy may possibly alter or slower the progression of LUTS/BPH,and potentially avoid unnecessary morbidities and mortalities from cardiovascular and metabolic diseases for those men.

关键词： Inflammation Insulin resistance Lower urinary tract symptoms Metabolic syndromeX Prostatic hyperplasia

A Potential Anti-metastatic Chinese Herb Andrographis paniculata—Its In Vitro Activities in Esophageal Cancer Cells and Endothelial Cells

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A Potential Anti-metastatic Chinese Herb Andrographis panicu...

Toxicological and histopathological effects of Dennettia tripetala seed used as grain protectant,food,and medicine

第十四届全国中药和天然药物学术研讨会

作者： Grace Gar-Lee Yue Julia Kin-Ming Lee kar-man chan Kwok-Pui Fung Philip Wai-Yan Chiu Clara Bik-San Lau The Chinese University of Hong Kong

＜正＞Esophageal cancer is associated with high postoperative recurrence and systemic *** adjuvant chemotherapy and concurrent radiation have shown favourable efficacies,searching for alternative treatments for metast...

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Food Quality and Safety 2017年第3期1卷 211-219页

作者： luke Chinaru Nwosu Chris Olukayode Adedire Emmanuel Oludele Ogunwolu Michael Olufemi Ashamo Food Technology Programme Department of BiologyFederal University of TechnologyAkureOndo State and Department of Crop and Environmental Protection University of AgricultureMakurdiBenue StateNigeria Department of Crop and Soil Science Faculty of AgricultureUniversity of Port HarcourtP.M.B.5323Port HarcourtRivers StateNigeria

The study revealed the safety of Dennettia tripetala seed on man and the *** male rats weighing 0.158-0.168 kg housed in standard cages with free access to food and water were used for the *** median lethal dose(LD50)was estimated using revised up and down *** LD50 for *** seed extract was 5785 mg/kg and this evoked paralysis in rats for 4 days coupled with discharge from the eyes and eventual *** least weight gain by the animals administered 75%seed powder of ***(4338.75 mg/kg)was an index of high powder concentration,whereas the weight loss experienced by group V animals is strongly attributed to chemical assault by permethrin designated as a standard *** high values of alanine aminotransferase(ALT),aspartate aminotransferase(AST),and urea in the groups administered 75%permethrin powder(4338.75 mg/kg)and 75%*** seed powder is an index of liver and kidney injury and *** presence of normal serum levels of ALT,AST,alkaline phosphatase,and creatinine;normal liver and kidney structures;and normal weight gains in the animal groups fed basal diet(control)and basal diet plus 25%*** is a strong indication that 25%*** seed powder(1446.25 mg/kg)supplementation is not toxic to the liver and kidney and therefore supports normal organ *** LD50 recorded strongly indicates that *** has a moderately high safety *** of less than 50%(2892.5 mg/kg)is recommended in the safe use of the plant material as grain protectant,food,and *** botanical insecticide,***,is safer than the conventional synthetic insecticide,permethrin,on account of the latter showing evidence of kidney damage.

关键词： Safety botanical insecticide permethrin supplementation kidney damage

A survey on treatment and quality of life(QoL) of hemophilia A(HA) and hemophilia B(HB) children in Zhejiang Province in Southern China

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A survey on treatment and quality of life(QoL) of hemophilia...

Pharmacokinetic Studies of Factor VIII in Chinese Boys with Severe Hemophilia A： A Single-Center Study

2014浙江省医学会血液病学学术年会

作者： Weiqun Xu Jianya Yang Yongmin Tang Koon-Hung luke Nancy L Young man-Chiu Poon Runhui Wu 浙江大学医学院附属儿童医院血液肿瘤科

*** of hemophilia in China is a challenge because of economic constraint and availability of clotting factors,The HTC at the Children’s Hospital,Zhejiang University started care and registration of hemophilia boys in Zhejiang Province in *** recently surveyed these boys on their treatment,joint and QoL status to form a baseline to direct their future ***:(1)Retrospective chart review and telephone survey for treatment and joint status;(2)CHO-

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Chinese Medical Journal 2018年第15期131卷 1780-1785页

作者： Zhen-Ping Chen Pei-jing Li Gang Li Ling Tang Ying-Zi Zhen Xin-Yi Wu Xiao-Ling Cheng Koon Hung luke Victor S Blanchette man-Chiu Poon Qiu-Lan Ding Run-Hui Wu Hematology Oncology Center Beijing Children's Hospital Capital Medical University Beijing Key Laboratory of Pediatric Hematology Oncology Discipline of Pediatrics Ministry of Education Beijing 100045 China Department of Pediatrics and Laboratory Medicine and Hemophilia Clinic Children's Hospital of Eastern Ontario and University of Ottawa National Key Ottawa. Ontario K1H8L1 Canada Department of Pediatrics and Child Health Evaluative Sciences Division of Hematology/Oncology Research Institute Hospital for Sick Children University of Toronto Toronto Ontario M5G lX8 Canada Department of Medicine Pediatrics and Oncology and Southern Alberta Rare Blood and Bleeding Disorders Comprehensive Care Program University of Calgary Foothills Hospital and Calgary Health Region Calgary Alberta T2N2T9 Canada Department of Laboratory Medicine Ruijin Hospital Shanghai Jiaotong University School of Medicine Shanghai 200025 China

Background： Although much attention has been paid to the pharmacokinetics （PKs） of different factor VIII （FVIlI） concentrates in persons with hemophilia A （HA）, limited information is available in young boys with severe HA. In this study, we aimed to assess the PK parameters of FVIII products in boys with severe HA in China. Methods： A total of 36 boys （plasma-derived [pd]-FVIII, n= 15; recombinant [r] FVIII, n = 21） were enrolled between January 2015 and May 2016 in Beijing Children＇s Hospital. PK characteristics of FVIII products were studied according to a reduced 4-sampling time point design （1 h, 9 h, 24 h, and 48 h postinfusion）. Results： The mean FVIII half-life （t1/2） was 10.99 ± 3.45 h （range 5.52-20.02 h）, the mean in vivo recovery （IVR） was 2.01 ± 0.42 IU/dl per IU/kg （range 1.24-3.02 IU/dl per IU/kg） and mean clearance （CL） of FVIII is 4.34 ± 1.58 ml·kg^-1·h ^-1 （range 2.29-7.90 ml·kg^-1·h·^-1）. We also analyzed the influence of several parameters that potentially modulate FVIII PK. The age was closely associated with FVIII half-life （R^2 = 0.32, P 〈 0.01 ）. The t1/2 of FVIII increased by 0.59 h per year. Besides age, yon Willebrand factor antigen （VWF：Ag） also was associated with FVIII half-life （R^2 = 0.52, P 〈 0.01）. Patients with blood Group O had a shorter FVIII halt-life than patients with non-O blood group （9.40 ± 0.68 h vs. 12.3 ± 0.79 h, t = 2.70, P = 0.01）. The FVIII IVR correlated with age （R^2 =0.21, P 〈 0.01） and VWF：Ag level （R^2 = 0.28, P 〈 0.01 ）. CL rates were taster in young patients and in those with low-VWF：Ag levels. CL rates of FVIII are higher in blood Group O versus non-blood Group O persons （5.02 ± 0.38 vs. 4.00 ± 0.32 ml·kg^-1·h^-1 , t = 2.53, P = 0.02）. Conclusions： Chinese boys with severe HA have similar PK values to other ethnic groups and large differences in FVIII PK between individual patients. Age, blood group, and VWF：Ag levels are important determining factors for FVlll CL.

关键词： Boys Factor VIII Hemophilia A Phannacokinetics