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Tissue adhesive,ROS scavenging and injectable PRP-based‘plasticine’for promoting cartilage repair

Regenerative Biomaterials 2024年第1期3卷 94-107页

作者： Shiao li Dawei Niu Haowei Fang Yancheng Chen Jinyan li Kunxi Zhang Jingbo Yin Peiliang fu Department of Orthopedics Shanghai Changzheng HospitalNaval Medical UniversityShanghai 200003P.R.China Department of Polymer Materials School of Materials Science and EngineeringShanghai UniversityShanghai 200444P.R.China

Platelet-rich plasma(PRP)that has various growth factors has been used clinically in cartilage repair.However,the short residence time and release time at the injury site limit its therapeutic effect.The present study fabricated a granular hydrogel that was assembled from gelatin microspheres and tannic acid through their abundant hydrogen bonding.Gelatin microspheres with the gelatin concentration of 10wt%and the diameter distribution of 1-10 lm were used to assemble by tannic acid to form the granular hydrogel,which exhibited elasticity under low shear strain,but flowability under higher shear strain.The viscosity decreased with the increase in shear rate.Meanwhile,the granular hydrogel exhibited self-healing feature during rheology test.Thus,granular hydrogel carrying PRP not only exhibited well-performed injectability but also performed like a‘plasticine’that possessed good plasticity.The granular hydrogel showed tissue adhesion ability and reactive oxygen species scavenging ability.Granular hydrogel carrying PRP transplanted to full-thickness articular cartilage defects could integrate well with native cartilage,resulting in newly formed cartilage articular fully filled in defects and well-integrated with the native cartilage and subchondral bone.The unique features of the present granular hydrogel,including injectability,plasticity,porous structure,tissue adhesion and reactive oxygen species scavenging provided an ideal PRP carrier toward cartilage tissue engineering.

关键词： cartilage regeneration granular hydrogel gelatin tannic acid PRP

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Reaction pathways and selectivity in the chemo-catalytic conversion of cellulose and its derivatives to ethylene glycol:A review

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Chinese Journal of Chemical Engineering 2024年第2期66卷 310-331页

作者： Yao li Yuchun Zhang Zhiyu li Huiyan Zhang Peng fu College of Agricultural Engineering and Food Science Shandong University of TechnologyZibo 255000China Key Laboratory of Energy Thermal Conversion and Control Ministry of EducationSchool of Energy and EnvironmentSoutheast UniversityNanjing 210096China

Biomass-to-ethylene glycol is an effective means to achieve high-value utilisation of cellulose but is hindered by low conversion efficiency and poor catalyst activity and stability.Glucose and cellobiose are derivatives of cellulose conversion to ethylene glycol,and it is found that studying the reaction process of both can help to understand the reaction mechanism of cellulose.It is desirable to develop a reusable,highly active catalyst to convert cellulose into ethylene glycol.This ideal catalyst might have one or more active sites described the conversion steps above.Here,we discuss the catalyst development of celluloseto-ethylene glycol,including tungsten,tin,lanthanide,and other transition metal catalysts,and special attention is given to the reaction mechanism and kinetics for preparing ethylene glycol from cellulose,and the economic advantages of biomass-to-ethylene glycol are briefly introduced.The insights given in this review will facilitate further development of efficient catalysts,for addressing the global energy crisis and climate change related to the use of fossil fuels.

关键词： Ethylene glycol Cellulose Catalyst Retro-aldol condensation Hydrolysis Kinetics

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Naturally Crosslinked Biocompatible Carbonaceous liquid Metal Aqueous Ink Printing Wearable Electronics for Multi-Sensing and Energy Harvesting

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Nano-Micro Letters 2024年第8期16卷 148-168页

作者： King Yan Chung Bingang Xu Di Tan Qingjun Yang Zihua li Hong fu Nanotechnology Center School of Fashion and TextilesThe Hong Kong Polytechnic UniversityHong Kong 999077People’s Republic of China Department of Mathematics and Information Technology The Education University of Hong KongHong KongPeople’s Republic of China

Achieving flexible electronics with comfort and durability comparable to traditional textiles is one of the ultimate pursuits of smart wearables.Ink printing is desirable for e-textile development using a simple and inexpensive process.However,fabricating high-performance atop textiles with good dispersity,stability,biocompatibility,and wearability for high-resolution,large-scale manufacturing,and practical applications has remained challenging.Here,waterbased multi-walled carbon nanotubes(MWCNTs)-decorated liquid metal(LM)inks are proposed with carbonaceous gallium–indium micro-nanostructure.With the assistance of biopolymers,the sodium alginate-encapsulated LM droplets contain high carboxyl groups which non-covalently crosslink with silk sericin-mediated MWCNTs.E-textile can be prepared subsequently via printing technique and natural waterproof triboelectric coating,enabling good flexibility,hydrophilicity,breathability,wearability,biocompatibility,conductivity,stability,and excellent versatility,without any artificial chemicals.The obtained e-textile can be used in various applications with designable patterns and circuits.Multi-sensing applications of recognizing complex human motions,breathing,phonation,and pressure distribution are demonstrated with repeatable and reliable signals.Self-powered and energy-harvesting capabilities are also presented by driving electronic devices and lighting LEDs.As proof of concept,this work provides new opportunities in a scalable and sustainable way to develop novel wearable electronics and smart clothing for future commercial applications.

关键词： Biocompatible Conductive ink Biopolymer E-textile Carbonaceous liquid metal

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Added Benefit of the Early-Morning-Orbit Satellite Fengyun-3E on the Global Microwave Sounding of the Three-Orbit Constellation

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Advances in Atmospheric Sciences 2024年第1期41卷 39-52页

作者： juan li Zhengkun QIN Guiqing liU Jing HUANG CMA Earth System Modeling and Prediction Centre Beijing 100081China State Key Laboratory of Severe Weather Chinese Academy of Meteorological SciencesBeijing 100081China Joint Center for Data Assimilation Research and Applications School of Atmospheric SciencesNanjing University of Information Science&TechnologyNanjing 210044China

The three-orbit constellation can comprehensively increase the spatial coverage of polar-orbiting satellites,but the polar-orbiting satellites currently in operation are only mid-morning-orbit and afternoon-orbit satellites.Fengyun-3E(FY-3E)was launched successfully on 5 July 2021 in China.As an early-morning-orbit satellite,FY-3E can help form a complete three-orbit observation system together with the mid-morning and afternoon satellites in the current mainstream operational system.In this study,we investigate the added benefit of FY-3E microwave sounding observations to the midmorning-orbit Meteorological Operational satellite-B(Met Op-B)and afternoon-orbit Fengyun-3D(FY-3D)microwave observations in the Chinese Meteorological Administration global forecast system(CMA-GFS).The results show that the additional FY-3E microwave temperature sounder-3(MWTS-3)and microwave humidity sounder-2(MWHS-2)data can increase the global coverage of microwave temperature and humidity sounding data by 14.8% and 10.6%,respectively.It enables the CMA-GFS to achieve nearly 100% global coverage of microwave-sounding observations at each analysis time.furthermore,after effective quality control and bias correction,the global biases and standard deviations of the differences between observations and model simulations are also reduced.Based on the Advanced Microwave Sounding Unit A and the Microwave Humidity Sounder onboard Met Op-B,and the MWTS-2 and MWHS-2 onboard FY-3D,adding the microwave sounding data of FY-3E can further reduce the errors of analysis results and improve the global prediction skills of CMA-GFS,especially for the southern-hemisphere forecasts within 96 hours,all of which are significant at the 95% confidence level.

关键词： data assimilation microwave temperature sounder MWTS-3

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MSC-YOLO:Improved YOLOv7 Based on Multi-Scale Spatial Context for Small Object Detection in UAV-View

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Computers, Materials & Continua 2024年第4期79卷 983-1003页

作者： Xiangyan Tang Chengchun Ruan Xiulai li Binbin li Cebin fu School of Computer Science and Technology Hainan UniversityHaikou570228China Hainan Blockchain Technology Engineering Research Center Hainan UniversityHaikou570228China School of Cyberspace Security(School of Cryptology) Hainan UniversityHaikou570228China

Accurately identifying small objects in high-resolution aerial images presents a complex and crucial task in thefield of small object detection on unmanned aerial vehicles(UAVs).This task is challenging due to variations inUAV flight altitude,differences in object scales,as well as factors like flight speed and motion blur.To enhancethe detection efficacy of small targets in drone aerial imagery,we propose an enhanced You Only Look Onceversion 7(YOLOv7)algorithm based on multi-scale spatial context.We build the MSC-YOLO model,whichincorporates an additional prediction head,denoted as P2,to improve adaptability for small objects.We replaceconventional downsampling with a Spatial-to-Depth Convolutional Combination(CSPDC)module to mitigatethe loss of intricate feature details related to small objects.furthermore,we propose a Spatial Context Pyramidwith Multi-Scale Attention(SCPMA)module,which captures spatial and channel-dependent features of smalltargets acrossmultiple scales.This module enhances the perception of spatial contextual features and the utilizationof multiscale feature information.On the Visdrone2023 and UAVDT datasets,MSC-YOLO achieves remarkableresults,outperforming the baseline method YOLOv7 by 3.0%in terms ofmean average precision(mAP).The MSCYOLOalgorithm proposed in this paper has demonstrated satisfactory performance in detecting small targets inUAV aerial photography,providing strong support for practical applications.

关键词： Small object detection YOLOv7 multi-scale attention spatial context

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A semantic segmentation-based underwater acoustic image transmission framework for cooperative SLAM

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Defence Technology（防务技术） 2024年第3期33卷 339-351页

作者： Jiaxu li Guangyao Han Shuai Chang Xiaomei fu School of Marine Science and Technology Tianjin UniversityTianjin 300072China

With the development of underwater sonar detection technology,simultaneous localization and mapping(SLAM)approach has attracted much attention in underwater navigation field in recent years.But the weak detection ability of a single vehicle limits the SLAM performance in wide areas.Thereby,cooperative SLAM using multiple vehicles has become an important research direction.The key factor of cooperative SLAM is timely and efficient sonar image transmission among underwater vehicles.However,the limited bandwidth of underwater acoustic channels contradicts a large amount of sonar image data.It is essential to compress the images before transmission.Recently,deep neural networks have great value in image compression by virtue of the powerful learning ability of neural networks,but the existing sonar image compression methods based on neural network usually focus on the pixel-level information without the semantic-level information.In this paper,we propose a novel underwater acoustic transmission scheme called UAT-SSIC that includes semantic segmentation-based sonar image compression(SSIC)framework and the joint source-channel codec,to improve the accuracy of the semantic information of the reconstructed sonar image at the receiver.The SSIC framework consists of Auto-Encoder structure-based sonar image compression network,which is measured by a semantic segmentation network's residual.Considering that sonar images have the characteristics of blurred target edges,the semantic segmentation network used a special dilated convolution neural network(DiCNN)to enhance segmentation accuracy by expanding the range of receptive fields.The joint source-channel codec with unequal error protection is proposed that adjusts the power level of the transmitted data,which deal with sonar image transmission error caused by the serious underwater acoustic channel.Experiment results demonstrate that our method preserves more semantic information,with advantages over existing methods at the same compression ratio.It also improves the error

关键词： Semantic segmentation Sonar image transmission Learning-based compression

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General Method of Combining Grover and Simon for Attacking Block Ciphers

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China Communications 2024年第6期21卷 237-245页

作者： fu Xiangqun Bao Wansu Shi Jianhong li Tan Henan Key Laboratory of Quantum Information and Cryptography PLA SSF IEUZhengzhou 450001China Synergetic Innovation Center of Quantum Information and Quantum Physics University of Science and Technology of ChinaHefei 230026China

The compatibility of different quantum algorithms should be considered when these algorithms are combined.In this paper,the method of combining Grover and Simon is studied for the first time,under some preconditions or assumptions.First,we give two preconditions of applying Grover’s algorithm,which ensure that the success probability of finding the marked element is close to 1.Then,based on these two preconditions,it is found out that the success probability of the quantum algorithm for FXconstruction is far less than 1.furthermore,we give the design method of the Oracle function,and then present the general method of combining Grover and Simon algorithm for attacking block ciphers,with success probability close to 1.

关键词： block ciphers post-quantum crypto quantum algorithms

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Aging-induced YTHDF aggregates impair mitochondrial function by trapping mitochondrial RNAs and suppressing their expression in the brain

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Protein & Cell 2024年第2期15卷 149-155页

作者： juan Zhang Dingfeng li Keqiang He Qiang liu Zhongwen Xie School of life Sciences Anhui Agricultural UniversityHefei 230036China State Key Laboratory of Tea Plant Biology and Utilization School of Tea and Food Sciences and TechnologyAnhui Agricultural UniversityHefei230036China Division of life Sciences and Medicine Hefei National Research Center for Physical Sciences at the MicroscaleUniversity of Science and Technology of ChinaHefei 230026China Department of Anesthesiology The First Affliated Hospital of USTCDivision of Life Sciences and MedicineUniversity of Science and Technology of ChinaHefei 230001China Anhui Province Key Laboratory of Biomedical Aging Research University of Science and Technology of ChinaHefei 230026China Center for Advanced Interdisciplinary Science and Biomedicine of IHM Division of Life Sciences and MedicineUniversity of Science and Technology of ChinaHefei 230026China

DearEditor,Brain aging is associated with a decrease in cognitive function,which is often accompanied by defective changes in mitochondrial morphology and reduction in mitochondrial function(Faitg et al.,2021).The main function of mitochondria is to produce energy in the form of ATP,which is vital to fulfill high energy demand of neurons,mainly for synaptic processes(Lee et al.,2018).Mitochondrial dysfunction acts as a key factor for age-related cognitive decline(Grimm and Eckert,2017).

关键词： function trapping

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Pre-MASLD:Should it be defined separately?

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Hepatobiliary & Pancreatic Diseases International 2024年第1期23卷 1-3页

作者： Hang-Kai Huang You-Ming li Cheng-fu Xu Department of Gastroenterology Zhejiang Provincial Clinical Research Center for Digestive Diseasesthe First Affiliated HospitalZhejiang University School of MedicineHangzhou 310003China

Nonalcoholic fatty liver disease(NAFLD)is one of the most common chronic liver diseases,yet it has not received sufficient attention[1].Over the past two decades,the overall global prevalence of NAFLD has risen from 25%to 37%[2].The disease burden of NAFLD is fueled by the epidemic of obesity and diabetes[3].It is estimated that more than half of patients with diabetes have NAFLD.

关键词： NAFLD liver diseases

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Improvement of Film Cooling Design for Turbine Vane Leading Edge Considering Combustor Outflow

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Journal of Thermal Science 2024年第1期33卷 311-327页

作者： WANG Xinyu liU Cunliang fu Zhongyi li Yang ZHU Huiren School of Power and Energy Northwestern Polytechnical UniversityXi'an 710072China AECC Hunan Aviation Powerplant Research Institute Zhuzhou 412002China

As the interaction between the combustor and the turbine in the aero-engine continues to increase,the film cooling design considering the combustor swirling outflow has become the research focus.The swirling inflow and high-temperature gas first affect the vane leading edge(LE).However,no practical improved solution for the LE cooling design has been proposed considering the combustor swirling outflow.In this paper,the improved scheme of showerhead cooling is carried out around the two ways of adopting the laid-back-fan-shaped hole and reducing the coolant outflow angle.The film cooling effectiveness(η) and the coolant flow state are obtained by PSP(pressure-sensitive-paint) and numerical simulation methods,respectively.The research results show that the swirling inflow increases the film distribution inhomogeneity by imposing the radial pressure gradient on the vane to make the film excessively gather in some positions.The showerhead film cooling adopts the laid-back-fan-shaped hole to reduce the momentum when the coolant flows out.Although this cooling scheme improves the film attachment and increases the surface-averaged film cooling effectiveness(η_(sur)) by as much as15.4%,the film distribution inhomogeneity increases.After reducing the coolant outlet angle,the wall-tangential velocity of the coolant increases,and the wall-normal velocity decreases.Under the swirl intake condition,both ηand the film distribution uniformity are significantly increased,and the growth of η_(sur) is up to 16.5%.This paper investigates two improved schemes to improve the showerhead cooling under the swirl intake condition to provide a reference for the vane cooling design.

关键词： turbine vane showerhead cooling swirling inflow laid-back-fan-shaped hole film hole inclination

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