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Gestational age-specific neonatal mortality in Hong Kong:a population-based retrospective study

World Journal of Pediatrics 2023年第2期19卷 158-169页

作者： Xue-Lian Wang Eman Leung Genevieve po Gee Fung Hugh Simon Lam Department of Neonatology Guangzhou Women and Children’s Medical CenterGuangzhou Medical UniversityGuangdong Provincial Clinical Research Center for Child HealthGuangzhouChina Department of Paediatrics Faculty of MedicineThe Chinese University of Hong KongHong Kong SARChina The Jockey Club School of Public Health and Primary Care Faculty of MedicineThe Chinese University of Hong KongHong Kong SARChina Department of Paediatrics 6/F Lui Che Woo Clinical Sciences BuildingPrince of Wales HospitalSha TinNew TerritoriesHong Kong SARChina

Background The neonatal period is the most vulnerable period during childhood,with the risk of death being the highest even in developed countries/*** Kong’s neonatal mortality(1‰)is among the world’s lowest and has remained similar for 15 *** study aimed to explore neonatal deaths in Hong Kong in detail and determine whether neonatal mortality is reducible at such a low *** Live births in public hospitals in Hong Kong during 01 Jan 2006–31 Dec 2017 were *** data were extracted from the electronic medical *** age-specific mortality was calculated,and the trends were analyzed using the Cochran–Armitage trend *** of death were summarized,and risk factors were identified in multivariate logistic regression *** In 490,034 live births,755 cases(1.54‰)died during the neonatal period,and 293(0.6‰)died during the post-neonatal *** neonatal mortality remained similar overall(P=0.17)and among infants born at 24–29 weeks’gestation(P=0.4),while it decreased in those born at 23(P=0.04),30–36(Pportion among cases who died(27.6%to 51.9%),with hemorrhagic conditions(24%)being the leading cause of *** anomalies were the leading cause of death in neonates born≥27 weeks’gestation(52%),but its cause-specific mortality decreased(P=0.002,0.6‰to 0.41‰),with most of the decrease attributed to trisomy 13/18 and multiple *** Reduction of neonatal mortality in developed regions may heavily rely on improved quality of perinatal and neonatal care among extremely preterm infants.

关键词： Cause of death Neonatal mortality population based Risk factor Trend

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Transient ischemic attack after mRNA-based COVID-19 vaccination during pregnancy:A case report

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World Journal of Clinical Cases 2022年第27期10卷 9929-9935页

作者： Chi-Han Chang Sheng-po Kao Dah-Ching Ding Department of Obstetrics and Gynecology Hualien Tzu Chi HospitalBuddhist Tzu Chi Medical FoundationTzu Chi UniversityHualien 970Taiwan

BACKGROUND Thrombocytopenia with thrombosis syndrome has been reported after vaccination against severe acute respiratory syndrome coronavirus 2 with two mRNA *** syndrome is characterized by thrombosis,especially cerebral venous sinus thrombosis,and may lead to *** women with stroke show higher rates of pregnancy loss and experience serious pregnancy *** present the case of a 24-year-old pregnant woman with a transient ischemic attack(TIA) that developed after vaccination with the Moderna mRNA-1273 vaccine(at 37 2/7 wk).CASE SUMMARY TIA occurred 13 d following the coronavirus disease *** 39 1/7 wk of pregnancy,the patient presented with sudden onset of right eye blurred vision with headache,dizziness with nausea,right-hand weakness,anomia,and *** symptoms lasted 3 h;TIA was *** test results revealed elevated D-dimer,cholesterol,and triglyceride *** magnetic resonance imaging showed no acute hemorrhagic or ischemic *** pregnancy 37 6/7 wk,she was admitted for cesarean delivery to reduce subsequent risk of stroke during *** mass index on admission was 19.8 kg/m~*** resonance angiography and transesophageal echocardiography showed no *** next day,a mature female baby weighing 2895 g and measuring 50 cm was *** scores were 8 and 9 in the first and fifth minutes.D-dimer levels decreased on postoperative day *** discharge,the autoimmune panel was within normal limits,including antinuclear and antiphospholipid *** TIA might be developed after the mRNA vaccines in pregnant women.

关键词： Pregnancy mRNA vaccine COVID-19 Stroke Transient ischemic attack Case report

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一种移动式多工况进料装置的设计研制

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广州化工 2024年第8期52卷 152-154页

作者：张瑜王雅郝妙莉候雄坡西安交通大学化学工程与技术学院陕西西安710049

反应精馏和萃取精馏是化工原理实验中极具代表性的特殊精馏实验,目前实验室有4套性能各异的配套设备。为促进新时期实验教学目标的进一步提高,优化实验设备的性能与寿命,设计研制了一种包含原料储罐、液体输送装置和移动支架的新型进料... 详细信息

反应精馏和萃取精馏是化工原理实验中极具代表性的特殊精馏实验,目前实验室有4套性能各异的配套设备。为促进新时期实验教学目标的进一步提高,优化实验设备的性能与寿命,设计研制了一种包含原料储罐、液体输送装置和移动支架的新型进料装置。新装置适用于现有设备,可解决进料不稳定、流量不准确等问题,有效提高设备利用率、性能和寿命,同时独立的进料装置在强化教学效果、引发学生思考与实践方面有突出效果。

关键词：特殊精馏实验进料装置移动式进料

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Artificial Intelligence in Internet of Things System for Predicting Water Quality in Aquaculture Fishponds

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Computer Systems Science & Engineering 2023年第9期46卷 2861-2880页

作者： po-Yuan Yang Yu-Cheng Liao Fu-I Chou Department of Intelligent Robotics National Pingtung UniversityPingtung900TaiwanChina Department of Electrical Engineering National Kaohsiung University of Science and TechnologyKaohsiung807TaiwanChina

Aquaculture has long been a critical economic sector in *** a key factor in aquaculture production efficiency is water quality,an effective means of monitoring the dissolved oxygen content(DOC)of aquaculture water is *** study developed an internet of things system for monitoring DOC by collecting essential data related to water *** intelligence technology was used to construct a water quality prediction model for use in a complete system for managing water *** aquaculture water quality depends on a continuous interaction among multiple factors,and the current state is correlated with the previous state,a model with time series is ***,this study used recurrent neural networks(RNNs)with sequential *** used RNNs such as long short-term memory model and gated recurrent unit(GRU)model have a memory function that appropriately retains previous results for use in processing current *** construct a suitable RNN model,this study used Taguchi method to optimize hyperparameters(including hidden layer neuron count,iteration count,batch size,learning rate,and dropout ratio).Additionally,optimization performance was also compared between 5-layer and 7-layer network *** experimental results revealed that the 7-layer GRU was more suitable for the application considered in this *** values obtained in tests of prediction performance were mean absolute percentage error of 3.7134%,root mean square error of 0.0638,and R-value of ***,thewater qualitymanagement system developed in this study can quickly provide practitioners with highly accurate data,which is essential for a timely response to water quality *** study was performed in collaboration with the Taiwan Industrial Technology Research Institute and a local fishery *** application of the system by the fishery company confirmed that the monitoring system is effective in improving the surviv

关键词： Fishery gated recurrent unit hyperparameter optimization long short-term memory Taguchi method water quality prediction

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Study on the performance of thin-film VCSELs on composite metal substrate

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Frontiers of Optoelectronics 2023年第4期16卷 1-11页

作者： William Anderson Lee Sanchez Shreekant Sinha po‑Yu Wang Ray‑Hua Horng Institute of Electronics Yang Ming Chiao Tung UniversityHsinchu 30010China

Thin film p-side up vertical-cavity surface-emitting lasers(VCSELs)with 940 nm wavelength on a composite metal(Copper/Invar/Copper;CIC)substrate has been demonstrated by twice-bonding transfer and substrate removing *** CIC substrate is a sandwich structure with a 10µm thick Copper(Cu)layer/30µm thick Invar layer/10µm thick Cu *** Invar layer was composed of Iron(Fe)and Nickel(Ni)with a proportion of 70:*** thermal expansion coefcient of the composite CIC metal can match that of the GaAs *** results that the VCSEL layers can be successfully transferred to CIC metal substrate without *** 1 mA current,the top-emitting VCSEL/GaAs and thin-flm VCSEL/CIC had a voltage of 1.39 and 1.37 V,*** optical output powers of VCSEL/GaAs and VCSEL/CIC were 21.91 and 24.40 mW,*** 50µm thick CIC substrate can play a good heat dissipation function,which results in improving the electrical and optical characteristics of thin flm VCSELs/*** VCSEL/CIC exhibited a superior thermal management capability as compared with VCSEL/*** obtained data suggested that VCSELs on a composite metal substrate not only afected signifcantly the characteristics of thin film VCSEL,but also improved considerably the device thermal performance.

关键词： Thin film VCSELs GaAs substrate Composite metal CIC substrate Twice-bonding transfer Electrical properties Heat dissipation

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数码显微互动教学模式对医学寄生虫学实验教学效果的影响

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基础医学教育 2024年第5期26卷 387-391页

作者：申金雁王晓晖李珀张丽山西医科大学基础医学院形态学实验室晋中030600 山西医科大学基础医学院寄生虫学教研室

文章为了比较和评估数码显微互动与传统教学模式对学生医学寄生虫学实验成绩和教学效果的影响,探讨实验课教学方式的改进,选取2021级临床医学本科二年级8个班学生,随机分为传统组和新模式组。传统组采取寄生虫学实验课传统教学模式,新... 详细信息

文章为了比较和评估数码显微互动与传统教学模式对学生医学寄生虫学实验成绩和教学效果的影响,探讨实验课教学方式的改进,选取2021级临床医学本科二年级8个班学生,随机分为传统组和新模式组。传统组采取寄生虫学实验课传统教学模式,新模式组采取“传统教学模式+Motic数码显微互动系统+数字化标本”教学模式,通过两样本秩和检验比较其实验成绩。通过问卷星向新模式组4个班的学生发放问卷,该网自动收集数据生成结果。该研究采用SPSS25.0统计软件,Mann-Whitney U检验分析表明,新模式组的实验课成绩高于传统组(z=5.584,P0.05)。问卷结果显示,73.08%的学生认为新教学模式采用数字化标本及互动教学模式提高了学习兴趣,50%的学生认为学习效率得以提高,65.38%的学生认为更好地实现了实验课的学习目标。新教学模式的教学效果优于传统教学模式。

关键词：医学寄生虫学实验教学教学模式 Motic数码显微互动系统数字化标本

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思政背景下大学物理课程翻转课堂教学模式的探索与实践——以光学仪器分辨本领为例

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大学物理 2024年第6期43卷 46-53页

作者：张颖刘文泼刘鸿鹏杨雄中国民航大学物理系天津300300

本文针对翻转课堂教学模式,结合三段式教学手段,围绕课前学习、课中讨论、课后拓展开展教学设计,对课前学习线上内容设计思路以及与实体课堂对接方式进行了深入探讨.通过传统文化、生活案例和热点事件将思政元素有机地融入到课程中,将... 详细信息

本文针对翻转课堂教学模式,结合三段式教学手段,围绕课前学习、课中讨论、课后拓展开展教学设计,对课前学习线上内容设计思路以及与实体课堂对接方式进行了深入探讨.通过传统文化、生活案例和热点事件将思政元素有机地融入到课程中,将抽象的物理概念变得更加鲜活直观、贴近实践.采取这套方案,课堂抬头率、学生参与度、问题答对率均有较大改善,通过调查问卷的形式,从教学模式可行性、教学方式可行性、内容可行性三个方面对学生认可度进行调研,发现学生认可度极高,此方案对教学质量的提高具有一定的参考价值.

关键词：翻转课堂微课设计大学物理

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Dense-Structured Network Based Bearing Remaining Useful Life Prediction System

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Computer Modeling in Engineering & Sciences 2022年第10期131卷 133-151页

作者： Ping-Huan Kuo Ting-Chung Tseng po-Chien Luan Her-Terng Yau Department of Mechanical Engineering National Chung Cheng UniversityChiayi62102Taiwan Advanced Institute of Manufacturing with High-Tech Innovations(AIM-HI) National Chung Cheng UniversityChiayi62102Taiwan

This work is focused on developing an effective method for bearing remaining useful life *** method is useful in accurately predicting the remaining useful life of bearings so that machine damage,production outage,and human accidents caused by unexpected bearing failure can be *** study uses the bearing dataset provided by FEMTO-ST Institute,Besancon,*** study starts with the exploration of neural networks,based on which the biaxial vibration signals are modeled and *** paper introduces pre-processing of bearing vibration signals,neural network model training and adjustment of training *** model is trained by optimizing model parameters and verifying its performance through *** proposed model’s superiority is also confirmed through a comparison with other *** this study,the neural network model is trained with various types of bearing data and can successfully predict the remaining useful *** algorithm proposed in this study achieves a prediction accuracy of coefficient of determination as high as 0.99.

关键词： Bearing neural network remaining useful life prediction machine learning

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Vitamin C exerts anti-cadmium induced fracture functions/targets:bioinformatic and biostructural findings

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Food Science and Human Wellness 2022年第5期11卷 1384-1391页

作者： Rong Li Songzuo Yu Xiao Liang Yu Li Keng po Lai Laboratory of Environmental pollution and Integrative Omics Guangxi Key Laboratory of Tumor Immunology and Microenvironmental RegulationGuilin Medical UniversityGuilin 541004China Department of Neurosurgery Guigang City People's HospitalThe Eighth Affi liated Hospital of Guangxi Medical UniversityGuigang 537100China

Background:Epidemiological data indicate an association between cadmium exposure and risk of bone fracture;however,clinical treatment of cadmium-induced fracture is *** vitamin C(VC)reportedly reduces cadmium-induced fracture,its pharmacological mechanism remains ***:Thus,we used a network pharmacology approach and molecular docking analysis to identify core targets,functional processes,and biological pathways involved in the anti-fracture action of ***:Bioinformatics identified 17 intersection targets of VC and cadmium-induced fracture,Nine core targets were characterized,including tumor protein p53,epidermal growth factor receptor,proto-oncogene c,mitogen-activated protein kinase-1(MAPK1),MAPK3,signal transducer and activator of transcription-3,MAPK14,prostaglandin-endoperoxide synthase 2,and estrogen receptor ***,findings of molecular docking analysis indicated that VC exerted effective binding capacity in cadmium-induced ***,biological processes,cell components,molecular functions,and pharmacological pathways involved in the action of VC against cadmium-induced fracture were identified and ***:Based on these findings,we conclude that VC exhibits its anti-cadmium-induced fracture effects by promoting osteoblastic regeneration and proliferation,and inhibiting inflammatory *** core targets may serve as biomarkers for diagnosing cadmium-induced fractures.

关键词： Cadmium Fracture Vitamin C Network pharmacology Mechanism

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高磅级旋转法兰结构设计及有限元分析

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河北科技大学学报 2024年第3期45卷 290-297页

作者：孙振辉刘坡李子健张建慧郭学文韩鹏彪河北科技大学材料科学与工程学院河北石家庄050018 河北省材料近净成形技术重点实验室河北石家庄050018 桂林航天工业学院机电工程学院广西桂林541004 苏州威尔汉姆堆焊技术有限公司江苏苏州215129

为了更好地评估旋转法兰在高温、高压下的工作状态,在现有压力级别(300~900磅)旋转法兰的基础上,对1 500磅和2 500磅旋转法兰进行结构设计和建模,并对模型强度和刚度进行校核,同时采用ABAQUS软件进行有限元静态力学分析。结果表明:各公... 详细信息

为了更好地评估旋转法兰在高温、高压下的工作状态,在现有压力级别(300~900磅)旋转法兰的基础上,对1 500磅和2 500磅旋转法兰进行结构设计和建模,并对模型强度和刚度进行校核,同时采用ABAQUS软件进行有限元静态力学分析。结果表明:各公称直径下旋转法兰的计算应力均小于许用应力,刚度满足使用要求;压力等级和法兰尺寸对旋转法兰应力分布存在一定影响,1 500磅旋转法兰存在芯套小端高颈以及垫片与法兰盘相接触2个应力集中区域,2 500磅旋转法兰除上述2个应力集中区域外,其芯套台阶处也会产生应力集中;最大应力均出现在芯套小端高颈处,且最大应力小于材料许用应力,设计的高磅级旋转法兰满足使用要求。研究结果进一步丰富了2 500磅旋转法兰结构设计案例,可为高磅级旋转法兰结构设计提供参考。

关键词：结构设计高磅级旋转法兰尺寸设计强度刚度校核有限元

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