Transient ischemic attack after mRNA-based COVID-19 vaccination during pregnancy:A case report

作     者：Chi-Han Chang Sheng-Po Kao Dah-Ching Ding 

作者机构：Department of Obstetrics and GynecologyHualien Tzu Chi HospitalBuddhist Tzu Chi Medical FoundationTzu Chi UniversityHualien 970Taiwan 

出 版 物：《World Journal of Clinical Cases》 (世界临床病例杂志)

年 卷 期：2022年第10卷第27期

页      面：9929-9935页

核心收录：

学科分类：1002[医学-临床医学] 100211[医学-妇产科学] 10[医学] 

主　　题：Pregnancy mRNA vaccine COVID-19 Stroke Transient ischemic attack Case report 

摘      要：BACKGROUND Thrombocytopenia with thrombosis syndrome has been reported after vaccination against severe acute respiratory syndrome coronavirus 2 with two mRNA *** syndrome is characterized by thrombosis,especially cerebral venous sinus thrombosis,and may lead to *** women with stroke show higher rates of pregnancy loss and experience serious pregnancy *** present the case of a 24-year-old pregnant woman with a transient ischemic attack(TIA) that developed after vaccination with the Moderna mRNA-1273 vaccine(at 37 2/7 wk).CASE SUMMARY TIA occurred 13 d following the coronavirus disease *** 39 1/7 wk of pregnancy,the patient presented with sudden onset of right eye blurred vision with headache,dizziness with nausea,right-hand weakness,anomia,and *** symptoms lasted 3 h;TIA was *** test results revealed elevated D-dimer,cholesterol,and triglyceride *** magnetic resonance imaging showed no acute hemorrhagic or ischemic *** pregnancy 37 6/7 wk,she was admitted for cesarean delivery to reduce subsequent risk of stroke during *** mass index on admission was 19.8 kg/m~*** resonance angiography and transesophageal echocardiography showed no *** next day,a mature female baby weighing 2895 g and measuring 50 cm was *** scores were 8 and 9 in the first and fifth minutes.D-dimer levels decreased on postoperative day *** discharge,the autoimmune panel was within normal limits,including antinuclear and antiphospholipid *** TIA might be developed after the mRNA vaccines in pregnant women.