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A Lightweight Multiscale Feature Fusion Network for Solar Cell Defect Detection

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Computers, Materials & Continua 2025年第1期82卷 521-542页

作者： Xiaoyun Chen lanyao Zhang Xiaoling Chen Yigang cen Linna Zhang Fugui Zhang School of Mechanical Engineering Guizhou UniversityGuiyang550025China School of Computer Science and Technology Beijing Jiaotong UniversityBeijing100044China

Solar cell defect detection is crucial for quality inspection in photovoltaic power generation *** the production process,defect samples occur infrequently and exhibit random shapes and sizes,which makes it challenging to collect defective ***,the complex surface background of polysilicon cell wafers complicates the accurate identification and localization of defective *** paper proposes a novel Lightweight Multiscale Feature Fusion network(LMFF)to address these *** network comprises a feature extraction network,a multi-scale feature fusion module(MFF),and a segmentation ***,a feature extraction network is proposed to obtain multi-scale feature outputs,and a multi-scale feature fusion module(MFF)is used to fuse multi-scale feature information *** order to capture finer-grained multi-scale information from the fusion features,we propose a multi-scale attention module(MSA)in the segmentation network to enhance the network’s ability for small target ***,depthwise separable convolutions are introduced to construct depthwise separable residual blocks(DSR)to reduce the model’s parameter ***,to validate the proposed method’s defect segmentation and localization performance,we constructed three solar cell defect detection datasets:SolarCells,SolarCells-S,and *** and SolarCells-S are monocrystalline silicon datasets,and PVEL-S is a polycrystalline silicon *** results show that the IOU of our method on these three datasets can reach 68.5%,51.0%,and 92.7%,respectively,and the F1-Score can reach 81.3%,67.5%,and 96.2%,respectively,which surpasses other commonly usedmethods and verifies the effectiveness of our LMFF network.

关键词： Defect segmentation multi-scale feature fusion multi-scale attention depthwise separable residual block

Neuroprotective potential for mitigating ischemia-reperfusion-induced damage

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Neural Regeneration Research 2025年第8期20卷 2199-2217页

作者： Zi Ye Runqing Liu Hangxing Wang Aizhen Zuo cen Jin Nan Wang Huiqi Sun Luqian Feng Hua Yang The Clinical Medical College Guizhou Medical UniversityGuiyangGuizhou ProvinceChina Division of Infectious Diseases Department of Internal MedicinePeking Union Medical College HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina School of Medical Imaging Guizhou Medical UniversityGuiyangGuizhou ProvinceChina Division of Gastroenterology First Affiliated Hospital of Zhengzhou UniversityZhengzhouHenan ProvinceChina The Second Clinical Medical College Lanzhou UniversityLanzhouGansu ProvinceChina Department of Neurosurgery Affiliated Hospital of Guizhou Medical UniversityGuiyangGuizhou ProvinceChina

Reperfusion following cerebral ischemia causes both structural and functional damage to brain tissue and could aggravate a patient's condition;this phenomenon is known as cerebral ischemia-reperfusion *** studies have elucidated the neuroprotective role of the sirtuin protein family(Sirtuins)in modulating cerebral ischemia-reperfusion ***,the potential of utilizing it as a novel intervention target to influence the prognosis of cerebral ischemia-reperfusion injury requires additional *** this review,the origin and research progress of Sirtuins are summarized,suggesting the involvement of Sirtuins in diverse mechanisms that affect cerebral ischemia-reperfusion injury,including inflammation,oxidative stress,blood-brain barrier damage,apoptosis,pyroptosis,and *** therapeutic avenues related to Sirtuins that may improve the prognosis of cerebral ischemia-reperfusion injury were also investigated by modulating Sirtuins expression and affecting representative pathways,such as nuclear factor-kappa B signaling,oxidative stress mediated by adenosine monophosphate-activated protein kinase,and the forkhead box *** review also summarizes the potential of endogenous substances,such as RNA and hormones,drugs,dietary supplements,and emerging therapies that regulate Sirtuins *** review also reveals that regulating Sirtuins mitigates cerebral ischemia-reperfusion injury when combined with other risk *** Sirtuins show promise as a potential target for the treatment of cerebral ischemiareperfusion injury,most recent studies are based on rodent models with circadian rhythms that are distinct from those of humans,potentially influencing the efficacy of Sirtuinstargeting drug ***,this review provides new insights into the role of Sirtuins in the pathology and treatment of cerebral ischemia-reperfusion injury.

关键词： apoptosis autophagy blood-brain barrier dietary supplements drug hormones inflammation neuroprotection oxidative stress prognosis pyroptosis reperfusion injury risk factors RNA therapeutics

How dopamine tunes parvalbumin interneurons in the hippocampus:new experimental observations in Alzheimer's disease

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Neural Regeneration Research 2025年第5期20卷 1405-1406页

作者： Livia la Barbera Paraskevi Krashia Annalisa Nobili Department of Medicine and Surgery UniversitàCampus Bio-Medico di RomaViaÁlvaro del PortilloRomeItaly Department of Experimental Neurosciences IRCCS Santa Lucia FoundationVia del Fosso di FioranoRomeItaly Department of Science and Technology for Sustainable Development and One Health UniversitàCampus Bio-Medico di RomaViaÁlvaro del PortilloRomeItaly

Despite decades of dedicated resea rch,Alzheimer's disease (AD) is an age-related and progressive neurodegenerative disorder for which the mechanisms of onset are sti unc *** is cha racterized by featured histological alterations including amyloid-beta (AB) plaque deposition,accumulation of neurofibrillary to ngles of hyperphosphorylated-tau,and neuronal loss,accompanied by progressive cognitive decline and behavioral changes.

关键词： Alzheimer alterations dopamine

TRMT6 and TRMT61A facilitated acute pancreatitis severity via regulation of neutrophil function

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Science China Life Sciences 2025年

作者： Yuan Dong Li Su Sin Man lam cen Yan Yalan Deng Guotao Lu Jinkui Yang Guanghou Shui Yingmei Feng Beijing Institute of Hepatology Beijing Youan HospitalCapital Medical University Department of Science and Development Beijing Youan HospitalCapital Medical University laboratory for Clinical Medicine Capital Medical University Neuroscience Research Institute Peking University Center of Medical and Health AnalysisPeking University State Key laboratory of Molecular Developmental Biology Institute of Genetics and Developmental BiologyChinese Academy of Sciences Pancreatic center Department of GastroenterologyAffiliated Hospital of Yangzhou UniversityYangzhou University Beijing Key laboratory of Diabetes Research and Care Department of EndocrinologyBeijing Tongren HospitalCapital Medical University

Dear Editor,Type 2 diabetes mellitus (T2DM) has been identified as a risk factor for increased severity in acute pancreatitis (AP)(Mikóet al,2018).However,to date,no studies have simultaneously included healthy individuals,T2DM patients,and AP patients to investigate which diabetes-associated metabolites are linked to AP severity.

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煤矿井下瓦斯无线监控系统关键技术研究

煤矿现代化 2025年第1期34卷 7-11页

作者：岑龙晋能控股煤业集团安全管理部山西大同037003

瓦斯浓度监控作为煤矿生产监控的重要环节,是煤矿安全生产的重要保障。目前煤矿瓦斯监控系统多基于电缆通信等有线方式,通信可靠性及监测范围均受井下环境因素制约严重,无法适应当前现代化煤矿需求。针对煤矿有线式瓦斯监控系统布线困... 详细信息

瓦斯浓度监控作为煤矿生产监控的重要环节,是煤矿安全生产的重要保障。目前煤矿瓦斯监控系统多基于电缆通信等有线方式,通信可靠性及监测范围均受井下环境因素制约严重,无法适应当前现代化煤矿需求。针对煤矿有线式瓦斯监控系统布线困难、监测范围小、抗干扰能力差等问题,提出了一种基于Zigbee无线传输网络的煤矿瓦斯监控系统设计方案。在煤矿原有线监控系统基础上进行改造,将现场传感器至瓦斯监控分站之间的有线传输通过Zigbee无线传输网络进行替换,具备网络容量大、组网扩展灵活等优点。同时对井下瓦斯浓度监控分站及传感器采集单元的无线收发模块进行设计,实现系统数据采集、传输及执行机构控制环节的无线交互,监测范围可通过增减无线节点灵活扩展,有效提高煤矿瓦斯监控灵活性及可靠性。经实验测试,系统无线通信能力较强、丢包率较低,数据传输通信及报警功能运行良好。

关键词：煤矿瓦斯监控无线传输 Zigbee

侵彻爆炸联合作用下超高性能混凝土遮弹层设计

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爆炸与冲击 2025年第1期45卷 88-101页

作者：程月华吴昊岑国华张瑜同济大学土木工程学院上海200092

为了准确评估超高性能混凝土(ultra-high performance concrete,UHPC)遮弹层在战斗部侵彻爆炸作用下的损伤破坏并建立可靠的计算方法,首先,开展了UHPC靶体抗105 mm口径弹体侵彻和5 kg TNT炸药爆炸联合作用试验,获取了侵彻作用后以及侵... 详细信息

为了准确评估超高性能混凝土(ultra-high performance concrete,UHPC)遮弹层在战斗部侵彻爆炸作用下的损伤破坏并建立可靠的计算方法,首先,开展了UHPC靶体抗105 mm口径弹体侵彻和5 kg TNT炸药爆炸联合作用试验,获取了侵彻作用后以及侵彻与爆炸联合作用后弹靶的损伤破坏数据;然后,建立了UHPC靶体抗弹体侵彻与爆炸作用的有限元模型,通过对上述试验和已有的有限厚UHPC板埋置装药爆炸试验进行数值仿真分析,验证了有限元模型和分析方法的可靠性;最后,对比了SDB、WDU-43/B和BLU-109/B等3种典型原型战斗部侵彻与爆炸联合作用下,UHPC遮弹层和普通混凝土遮弹层的临界贯彻和震塌厚度。结果表明:3种战斗部侵彻爆炸联合作用下,遮弹层的临界贯穿厚度和震塌厚度范围分别为1.30~2.60 m和1.70~5.00 m,相应的临界贯穿系数和震塌系数范围分别为1.81~2.17和2.46~4.17;与普通混凝土遮弹层对比,3种战斗部侵彻爆炸联合作用下UHPC遮弹层的开坑直径减小了34.4%~42.4%,临界贯穿和震塌厚度分别减小了7.1%~31.6%和39.7%~52.8%。研究结果可为UHPC遮弹层的抗力评估和设计提供参考。

关键词：超高性能混凝土遮弹层侵彻爆炸防护设计

A modified spontaneous emulsification solvent diffusion method for the preparation of curcumin-loaded PLGA nanoparticles with enhanced in vitro anti-tumor activity

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Frontiers of Materials Science 2014年第4期8卷 332-342页

作者： cen CHEN Institute of Biomaterials and Marine Biological Resources College of Life Sciences Zhejiang Sci-Tech University Hangzhou 310018 China Bio-X center Zhejiang Sci-Tech University Hangzhou 310018 China

To improve the anti-tumor activity of hydrophobic drug curcumin, we prepared curcumin-loaded PLGA nanoparticles （PLGA-Cur NPs） through a modified spontaneous emulsification solvent diffusion （modified-SESD） method. The influence of main preparation parameters was investigated, such as the volume ratio of binary organic solvents and the concentration of surfactant. Results indicated that the synthesized regular spherical PLGA NPs with the average diameter of 189.7 nm exhibited relatively higher yield （58.9%）, drug loading （11.0% （w/w）） and encapsulation efficiency （33.5%）, and also a controllable drug release profile. In order to evaluate the in vitro cytotoxicity of the prepared NPs, MTT assay was conducted, and results showed that the NPs could effectively inhibit HL60 and HepG2 cells with lower IC50 values compared with free curcumin. Furthermore, confocal microscopy together with flow cytometry analysis proved the enhanced apoptosis-inducing ability of PLGA-Cur NPs. Polymeric NP formulations are potential to be used for hydrophobic drug delivery systems in cancer therapy.

关键词： curcumin PLGA nanoparticle modified spontaneous emulsificationsolvent diffusion (modified-SESD) anti-tumor

Characteristics and Weldability of Resistance Plug Welding of Dissimilar Steels

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Journal of Wuhan University of Technology(Materials Science) 2023年第6期38卷 1463-1471页

作者： cen Yaodong CHEN Lin MA Xiao School of Materials and Metallurgy Inner Mongolia University of Science and TechnologyBaotou 014010China

TRIP980 high-strength steel plate/SPCC low-carbon steel plate were welded by RPW. The key factors such as size and material of filler were studied, and the structure, fusion ratio and mechanical properties of the RPW joint were analyzed. The experimental results show that the calculation formulas of the length and diameter of the filler were designed reasonably. Q235 as a filler for RPW of TRIP980 high-strength steel plate/SPCC low-carbon steel plate is suitable according to schaeffler organization chart. The deposited metal of RPW joint is in the shape of “spool”,and the base metal and cap of deposited metal are alternately combined. The deposited metal has the characteristics of “locking” as rivets, which is beneficial to the improvement of mechanical properties of RPW joint. The nugget of RPW joint is uniform without deviates. TRIP980 high-strength steel plate, SPCC low-carbon steel plate, and filler were metallurgically bonded in the RPW joint.

关键词： dissimilar steel resistance plug welding nugget

A Lightweight Compact Lithium-Ion Battery Thermal Management System Integratable Directly with EV Air Conditioning Systems

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Journal of Thermal Science 2022年第6期31卷 2363-2373页

作者： LIN Bichao cen Jiwen JIANG Fangming laboratory of Advanced Energy Systems Guangzhou Institute of Energy ConversionChinese Academy of SciencesGuangzhou510640China CAS Key laboratory of Renewable Energy Guangzhou 510640China Guangdong Provincial Key laboratory of New and Renewable Energy Research and Development Guangzhou 510640China University of Chinese Academy of Sciences Beijing 100049China

This paper discusses an improved thermal management system to ameliorate the performance of lithium-ion battery storage systems for electric vehicles(EVs) applications. A compact and lightweight cold plate is designed and fabricated to fit 18650-type lithium-ion batteries, using aluminum-finned copper tubes. A dynamic temperature PID(proportional, integral, differential) control algorithm for electronic expansion valves is developed to study using EV air conditioning refrigerant, R134a, to control battery modules’ temperature with this compact and lightweight thermal management system. The experimental results show that the proposed battery thermal management system can effectively control the battery module’s temperature. In addition, during 1C discharge, when the PID temperature algorithm control scheme is used, the maximum temperature difference across the battery module peaks at less than 4℃, and the maximum temperature within the battery module is less than 36℃.

关键词： electric vehicles air conditioning system battery thermal management finned tube two-phase flow