TRMT6 and TRMT61A facilitated acute pancreatitis severity via regulation of neutrophil function

作     者：Yuan Dong Li Su Sin Man Lam Cen Yan Yalan Deng Guotao Lu Jinkui Yang Guanghou Shui Yingmei Feng 

作者机构：Beijing Institute of HepatologyBeijing Youan HospitalCapital Medical University Department of Science and DevelopmentBeijing Youan HospitalCapital Medical University Laboratory for Clinical MedicineCapital Medical University Neuroscience Research InstitutePeking University Center of Medical and Health AnalysisPeking University State Key Laboratory of Molecular Developmental BiologyInstitute of Genetics and Developmental BiologyChinese Academy of Sciences Pancreatic CenterDepartment of GastroenterologyAffiliated Hospital of Yangzhou UniversityYangzhou University Beijing Key Laboratory of Diabetes Research and CareDepartment of EndocrinologyBeijing Tongren HospitalCapital Medical University 

出 版 物：《Science China Life Sciences》 (中国科学:生命科学(英文版))

年 卷 期：2025年

核心收录：

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

基　　金：supported by the National Natural Science Foundation of China (82070841 to Yingmei Feng 82200715to Yuan Dong 32321004 and 92357308 to Guanghou Shui) 

摘      要：Dear Editor,Type 2 diabetes mellitus (T2DM) has been identified as a risk factor for increased severity in acute pancreatitis (AP)(Mikóet al,2018).However,to date,no studies have simultaneously included healthy individuals,T2DM patients,and AP patients to investigate which diabetes-associated metabolites are linked to AP severity.