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Surgical outcome of pancreatic cancer using radical antegrade modular pancreatosplenectomy procedure

World Journal of Gastroenterology 2012年第39期18卷 5595-5600页

作者： Ye Rim Chang Sung-Sik Han Sang-Jae Park seung Duk lee Tae Suk Yoo Young-kyu Kim Tae Hyun Kim Sang Myung Woo Woo Jin lee Eun kyung Hong Department of Surgery Seoul National University HospitalSeoul 110-744South Korea Center for Liver Cancer National Cancer CenterGyeonggido 411-764South Korea

AIM:To evaluate the surgical outcomes following radical antegrade modular pancreatosplenectomy (RAMPS) for pancreatic cancer. METHODS:Twenty-four patients underwent RAMPS with curative intent between January 2005 and June 2009 at the National Cancer Center, South Korea. Clinicopathologic data, including age, sex, operative findings, pathologic results, adjuvant therapy, postop-erative clinical course and follow-up data were retro-spectively collected and analyzed for this study. RESULTS:Twenty-one patients (87.5%) underwent distal pancreatectomy and 3 patients (12.5%) underwent total pancreatectomy using RAMPS. Nine patients (37.5%) underwent combined vessel resection, including 8 superior mesenteric-portal vein resections and 1 celiac axis resection. Two patients (8.3%) underwent combined resection of other organs, including the colon, stomach or duodenum. Negative tangential margins were achieved in 22 patients (91.7%). The mean tumor diameter for all patients was 4.09 ± 2.15 cm. The 2 patients with positive margins had a mean diameter of 7.25 cm. The mean number of retrieved lymph nodes was 20.92 ± 11.24 and the node positivity rate was 70.8%. The median survival of the 24 patients was 18.23 ± 6.02 mo. Patients with negative margins had a median survival of 21.80 ± 5.30 mo and those with positive margins had a median survival of 6.47 mo (P = 0.021). Nine patients (37.5%) had postoperative complications, but there were no postoperative mortalities. Pancreatic fistula occurred in 4 patients (16.7%):2 patients had a grade A fistula and 2 had a grade B fistula. On univariate analysis, histologic grade, positive tangential margin, pancreatic fistula and adjuvant therapy were significant prognostic factors for survival. CONCLUSION:RAMPS is a feasible procedure for achieving negative tangential margins in patients with carcinoma of the body and tail of the pancreas.

关键词： Carcinoma Pancreas Surgical resection Sur-vival Radical antegrade modular pancreatosplenectomy

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Estimation of marine winds in and around typhoons using multi-platform satellite observations: Application to Typhoon Soulik (2018)

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Frontiers of Earth Science 2022年第1期16卷 175-189页

作者： seung-Woo lee Sung Hyun NAM Duk-Jin KIM School of Earth and Environmental Sciences College of Natural SciencesSeoul National UniversitySeoul 08826Republic of Korea Research Institution of Oceanography College of Natural SciencesSeoul National UniversitySeoul 08826Republic of Korea

Estimating horizontal winds in and around typhoons is important for improved monitoring and prediction of typhoons and mitigating their ***,we present a new algorithm for estimating typhoon winds using multiple satellite observations and its application to Typhoon Soulik(2018).Four kinds of satellite remote sensing data,along with their relationship to typhoon intensity,derived statistically from hundreds of historical typhoon cases,were merged into the final product of typhoon wind(MT wind):(1)geostationarysatellite-based infrared images(IR wind),(2)passive microwave sounder(MW wind),(3)feature-tracked atmospheric motion vectors,and (4)scatterometer-based sea surface winds(SSWs).The algorithm was applied to two cases(A and B)of Typhoon Soulik and validated against SSWs independently retrieved from active microwave synthetic aperture radar(SAR)and microwave radiometer(AMSR2)images,and vertical profiles of wind speed derived from reanalyzed data and dropsonde *** Case A(open ocean),the algorithm estimated the realistic maximum wind,radius of maximum wind,and radius of 15 m/s,which could not be estimated using the reanalysis data,demonstrating reasonable and practical ***,for Case B(when the typhoon rapidly weakened just before making landfall in the Korean Peninsula),the algorithm significantly overestimated the parameters,primarily due to the overestimation of typhoon *** study highlights that realistic typhoon winds can be monitored continuously in real-time using multiple satellite observations,particularly when typhoon intensity is reasonably well predicted,providing timely analysis results and products of operational importance.

关键词： sea surface wind multi-platform satellites Typhoon Soulik(2018)

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Probiotics prophylaxis in pyelonephritis infants with normal urinary tracts

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World Journal of Pediatrics 2016年第4期12卷 425-429页

作者： seung Joo lee Jihae Cha Jung Won lee Department of Pediatrics Ewha Women's University School of Medicine Kangnam Sacred Heart Hospital Hallym University School of Medicine

Background:Pyelonephritis in infants is considered as a major factor for the formation of renal *** prevent recurrent pyelonephritis and renal damage,prophylaxis is extremely *** aim of this study was to compare the effectiveness of probiotic and antibiotic prophylaxis or no-prophylaxis in infants with pyelonephritis and normal urinary ***:Altogether 191 infants,who were diagnosed with acute pyelonephritis,proven to have normal urinary tracts and followed up for 6 months on prophylaxis,were retrospectively *** to the types of prophylaxis,the infants were divided into three groups[probiotics(Lactobacillus species),antibiotics(trimethoprim/sulfamethoxazole,TMP/SMX),and noprophylaxis].The incidence of recurrent urinary tract infection(UTI)during 6 months after the development of pyelonephritis,main causative uropathogens,and its antimicrobial sensitivities were ***:The incidence of recurrent UTI in the probiotic group was 8.2%,which was significantly lower than 20.6%in the no-prophylaxis group(P=0.035)and was not significantly different from 10.0%of the antibiotic group(P=0.532).The significant difference between the probiotic and no-prophylaxis groups was seen only in male infants(P=0.032).The main causative organism of recurrent UTI was Escherichia coli(***),which was not different among the three groups(P=0.305).The resistance rate of *** to TMP/SMX was 100%in the antibiotic group,which was significantly higher than 25.0%in the probiotic group and 41.7%in the no-prophylaxis group(P=0.008).Conclusion:Probiotic prophylaxis was more effective in infants with pyelonephritis and normal urinary tract than in those with *** could be used as a natural alternative to antibiotic prophylaxis.

关键词： antibiotic prophylaxis antibiotic resistance probiotic prophylaxis pyelonephritis

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The 5-year functional outcomes after radical prostatectomy： a real-life experience in Korea

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Asian Journal of Andrology 2010年第6期12卷 835-840页

作者： Sung kyu Hong seung Hwan Doo Dae Sung Kim Won Ki lee Hong Zoo Park Ji Hyun Park Seong Jin Jeong Cheol Yong Yoon Seok-Soo Byun Sang Eun lee Department of Urology Seoul National University Bundang Hospital Seongnam Kyunggi-do 463-707 Korea

We investigated the functional outcomes regarding erectile function and urinary continence up to 5 years following radical prostatectomy （RP） in a cohort of Korean men. We retrospectively analyzed the clinicopathologic data of 85 Korean men who received open uni- or bilateral nerve-sparing RP for clinically localized prostate cancer and were followed up for at least 5 years postoperatively. From medical records, patients＇ status regarding urinary and erectile function at baseline and postoperative followups after RP was assessed. At 24 and 60 months after RP, proportions of subjects continent （no pads used） were 89.4% and 97.6%, respectively （P = 0.007）. Excluding subjects （n = 24） who preoperatively reported having severe erectile dysfunction or lacked relevant informations, proportions of subjects capable of having vaginal intercourse regardless of erectile aid usage were 47.5% and 37.7% at 24 and 60 months from RP, respectively （P = 0.022）. Patient＇s age at surgery （P = 0.047） and salvage radiation therapy （P = 0.026） were observed to be significant predictors of having erections sufficient for intercourse at 60 months from RP in multivariate analysis. Our results showed that while patients＇ postoperative status regarding urinary continence at 2 years from RP is generally maintained or improved at 5 year point, erectile function was observed to significantly declined from 2 years to 5 years following RP. Such decline in erectile function following RP may be more significant among men who were relatively older at surgery or those who received salvage therapy during postoperative follow-ups.

关键词： impotence prostatectomy prostatic neoplasm urinary incontinence

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Development of a Measurement System Far-IR Using a MCT Sensor

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Journal of Donghua University(English Edition) 2006年第5期23卷 80-82页

作者： Hangjin Cho seung-A lee Jooyong Kim Department of Textile Engineering Soongsil University Seoul Korea

The far-infrared radiation （Far-IR） has good effects on us, promoting the circulation of the blood and metabolic. So textile products including far-IR have been developed. But it is very difficult to measure the amount of far-IR in the textile quicHy and correctly. Newly developed Mercury Cadmium Telluride （MCT） sensor system could solve this problem.

关键词： far-lR frequency radiation MCT.

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CONVEX CONTROLLER DESIGN APPLIED TO AC INDUCTION MOTOR TO SATISFY MULTIPLE SIMULTANEOUS SPECIFICATIONS

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Chinese Journal of Mechanical Engineering 2006年第4期19卷 475-479页

作者： lee seung-Ju SUN Dong MILLS James K Department of Mechanical and Industrial Engineering University of Toronto Toronto MSS 3G8 Canada Department of Manufacturing Engineering and Engineering Management City University of Hong Kong Hong Kong SAR China

The application of a closed-loop specification oriented feedback control design method, which addresses the design of controllers to satisfy multiple simultaneous conflicting closed-loop performance specifications is presented. The proposed approach is well suited to the design of controllers which must meet a set of conflicting performance specifications. Gain tuning is central to the design process, however, the tuning process is greatly simplified over that presented by the problem of tuning a PID controller for example. The proposed control method is applied to an AC induction motor, with an inner-loop flux vector controller applied to design a position control system. Experimental results verify the effectiveness of this method.

关键词： Convex controller design Multiple simultaneous specifications AC induction motor Nonlinear control

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Increased intestinal macromolecular permeability and urine nitrite excretion associated with liver cirrhosis with ascites

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World Journal of Gastroenterology 2008年第24期14卷 3884-3890页

作者： Soong lee seung-Cheol Son Moon-Jong Han Woo-Jin Kim Soo-Hyun Kim Hye-Ran Kim Woo-kyu Jeon Ki-Hong Park Myung-Geun Shin Department of Internal Medicine College of MedicineSeonam University and Seonam University Hospital Department of Laboratory Medicine Chonnam National University Medical School and Chonnam National University Hwasun Hospital Brain Korea 21 Project Center for Biomedical Human Resources at Chonnam National University Medical School Department of Internal Medicine Kangbuk Samsung HospitalSungkyunkwan University School of Medicine Korea Polymer Testing & Research Institute Ltd.

AIM： To determine intestinal permeability, the serum tumor necrosis factor （TNF）-α level and urine nitric oxide （NO） metabolites are altered in liver cirrhosis （LC） with or without ascites. METHODS： Fifty-three patients with LC and 26 healthy control subjects were enrolled in the study. The intestinal permeability value is expressed as the percentage of polyethylene glycol （PEG） 400 and 3350 retrieval in 8-h urine samples as determined by high performance liquid chromatography. Serum TNF-α concentrations and urine NO metabolites were determined using an enzyme-linked immunosorbent assay （ELISA） and Greiss reaction method, respectively. RESULTS： The intestinal permeability index wassignificantly higher in patients with LC with ascites than in healthy control subjects or patients with LC without ascites （0.88 ± 0.12 vs 0.52 ± 0.05 or 0.53 ± 0.03, P 〈 0.05） and correlated with urine nitrite excretion （r = 0.98）. Interestingly, the serum TNF-α concentration was significantly higher in LC without ascites than in control subjects or in LC with ascites （198.9 ± 55.8 pg/mL vs 40.9 ± 12.3 pg/mL or 32.1 ± 13.3 pg/mL, P 〈 0.05）. Urine nitrite excretion was significantly higher in LC with ascites than in the control subjects or in LC without ascites（ 1170.9± 28.7 μmol/L vs 903.1 ± 55.1 μmol/L or 956.7 ± 47.7 μmol/L, P 〈 0.05）. COMCLUSIOM： Increased intestinal macromolecular permeability and NO is probably of importance in the pathophysiology and progression of LC with ascites, but the serum TNF-α concentration was not related to LC with ascites.

关键词： Intestinal permeability Tumor necrosisfactor-R Nitric oxide Liver cirrhosis Ascites

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Remote Navigation of Turtle by Controlling Instinct Behavior via Human Brain-computer Interface

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Journal of Bionic Engineering 2016年第3期13卷 491-503页

作者： Cheol-Hu Kim Bongjae Choi Dae-Gun Kim Serin lee Sungho Jo Phill-seung lee Department of Mechanical Engineering Korea Advanced Institute of Science and Technology (KAIST) 373-1 Guseong-dong Yuseong-gu Daejeon 34141 Republic of Korea School of Computing Science Korea Advanced Institute of Science and Technology (KAIST) 373-1 Guseong-dong Yuseong-gu Daejeon 34141 Republic of Korea Instituteforlnfocomm Research 1 Fusionopolis Way #21-01 Connexis (South Tower) 138632 Singapore

Brain-Computer Interface （BCI） techniques have advanced to a level where it is now eliminating the need lor hand-based activation. This paper presents a novel attempt to remotely control an animal＇s behavior by human BCI using a hybrid of Event Related Desynchronization （ERD） and Steady-State Visually Evoked Potential （SSVEP） BCI protocols. The turtle was chosen as the target animal, and we developed a head-mounted display, wireless communication, and a specially designed stimulation device for the turtle. These devices could evoke the turtle＇s instinctive escape behavior to guide its moving path, and turtles were remotely controlled in both indoor and outdoor environments. The system architecture and design were presented. To demon- strate the feasibility of the system, experimental tests were performed under various conditions. Our system could act as a framework for future human-animal interaction systems.

关键词： brain-computer interface turtle (Trachemys scripta elegans) remote navigation instinct behaviour escape be- havior

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Efficient and secure source authentication scheme for multicast user authentication

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Journal of Central South University 2013年第10期20卷 2741-2746页

作者： JEONG Yoon-su lee Sang-hyuk SHIN seung-soo Department of Information Communication Engineering Mokwon University Department of Electrical and Electronic Engineering Xi’an Jiaotong-Liverpool University Department of Information Security Tongmyong University

Multicast technology application has been widely utilized in broadband internet. Source authentication is one of the most needs for many multicast applications transferring real-time information such as stream video and online news. Because multicast current services provided to the group members are changed dynamically, data transferring by a group member is not used by the recipient. In order to verify the identity of the sender who sent the packet and to make sure that the data have not been tampered, an optimized source authentication scheme has been proposed to transfer the authentication information not to the next-door packet. The proposed method for multiple packets authenticates the source with a limited number of electronic signatures. The proposed method can reduce overhead compared to the method by adding a digital signature for every packet. In addition, by sending the generated electronic signature to the first packet and the last packet, it prevents the loss of consecutive packets, as well as a source authentication can be provided in real-time services.

关键词： multicast packet source authentication broadband Internet

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Numerical evaluation of buckling behavior in space structure considering geometrical parameters with joint rigidity

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Journal of Central South University 2014年第3期21卷 1115-1124页

作者： Su-Deok Shon kyung-Ju Hwang seung-Jae lee School of Architectural Engineering Korea University of Technology and Education School of Architecture University of Seoul

The buckling behavior of single layer space structure is very sensitive. The joint rigidity, moreover, is one of the main factors of stability which may determine the entire failure behavior. Thus, the reasonable stiffness of joint system, which is neither total pin assumption nor perfect fix condition, is very important to apply to the real single layer space one. Therefore, the purpose of this work was to investigate the buckling behavior of single layer space structure, using the development of the upgraded stiffness matrix for the joint rigidity. To derive tangential stiffness matrix, a displacement function was assumed using translational and rotational displacement at the node. The geometrical nonlinear analysis was simulated not only with perfect model but also with imperfect one. As a result, the one and two free nodal numerical models were investigated using derived stiffness matrix. It was figured out that the buckling load increases in proportion to joint rigidity with rise-span ratio. The stability of numerical model is very sensitive with the initial imperfection, responding of bifurcation in the structure.

关键词： space frame geometric nonlinearity snap-through bifurcation initial imperfection joint rigidity

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