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Journal of Environmental Sciences 2024年第1期135卷 630-639页

作者： Xi Zhang Takuya murakami Jinhe Wang Masahide Aikawa Faculty of Environmental Engineering The University of Kitakyushu1-1HibikinoWakamatsuKitakyushuFukuoka 808-0135Japan Resources and Environment Innovation Research Institute School of Municipal and Environmental EngineeringShandong Jianzhu UniversityJinan 250101China

In the suburbs of Kitakyushu,Japan,the inorganic aerosol mass concentration(IAM)was about 32.7μg/m^(3),with the aerosol pH of *** study the thermodynamics of aerosol when its individual components'concentration is reduced,sensitive tests were performed using the ISORROPIAⅡmodel,in which the seven control species—TNaCl,TNH_(4)^(+),TSO_(4)^(2-),TNO_(3)^(-),TMg^(2+),TK^(+),and TCa^(2+)—were taken into *** and inorganic aerosol pH after reducing TNaCl,TNO_(3)^(-),TMg^(2+),TK^(+),and TCa^(2+)responded linearly(0%≤concentration reduction ratio(CRR)≤100%,with the exception of 100%in TNaCl);the nonlinear variations of these two parameters could be observed by controlling TNH_(4)^(+)and TSO_(4)^(2-).Unexpected aerosol behavior occurred at 100%reduction of TNaCl,which was caused by the sudden increase of NO_(3)^(-),NH_(4)^(+),and aerosol liquid water content(ALWC);the increase of IAM was also observed after controlling TSO_(4)^(2-)(60%≤CRR≤100%)and TCa^(2+)(0%≤CRR≤100%),which was mainly related to the variation of ALWC driven by the response of CaSO_(4).Multiple regression analysis showed that ALWC was statistically and strongly related to the variations of NO_(3)^(-),Cl-,SO_(4)^(2-),HSO_(4)^(-),HNO_(3),and NH_(3)(P<0.05),with regression coefficients of 1.68,5.23,1.83,2.81,0.34,and 0.57,*** highest coefficient(5.23)was found for Cl^(-),revealing that sea salts significantly influenced particle ***,this study comprehensively investigated aerosol characteristics and inner responses for the reduction of components,which is of great significance for a better understanding of atmospheric chemistry in Kitakyushu,Japan.

关键词： Sensitive tests Reduction Gas-particle conversion process Aerosol liquid water content Sea salts

Optimizing piezoelectric performance of complex perovskite through increasing diversity of B-site cations

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Journal of Materials Science & Technology 2024年第3期170卷 78-86页

作者： Mengdi Cheng Dongyan Zhang Yangxi Yan Zhimin Li Pangpang Wang Ri-ichi murakami School of Advanced Materials and Nanotechnology Xidian UniversityXi’an 710126China Nanomaterials Group Institute of SystemInformation Technologies and Nanotechnologies(ISIT)Fukuoka Industry-Academia Symphonicity(FiaS)4-1 KyudaishinmachiNishi-kuFukuoka 819-0388Japan School of Mechanical Engineering Chengdu UniversityChengdu 610106China

Piezoelectric materials with unique properties are hugely appealing for high sensitivity sensors and ultrasonic ***,Pb(Ni_(1/3)Nb_(2/3))O_(3)-Pb(Yb_(1/2)Nb_(1/2))O_(3)-PbTiO_(3)piezoelectric system was designed and investigated in *** optimized piezoelectric response(d_(33)=826 pC/N,d_(33)∗=1017 pm/V)together with good temperature stability and negligible performance degradation up to 10^(6) cycles was achieved in 0.58PNN-0.10PYN-0.32PT *** analysis revealed the amplification of intrinsic and extrinsic contributions in MPB region due to more spontaneous polarization orientations and an increase in chemical disorder of system after the introduction of *** origin of high piezoelectric response was investigated through the combination of scanning electron microscopy and piezoresponse force *** diversity of B-site cations was shown to enhance local structural heterogeneity,weaken long-range ferroelectric ordered domains,and lower free energy barrier via the formation of nanodomain configuration that promoted polarization rotation,thereby improving piezoelectric properties of the ***,it is suggested that increasing the diversity of B-site cations is an effective strategy for achieving outstanding piezoelectric performance.

关键词： PNN-PYN-PT ceramics Piezoelectricity enhancement Relaxation behavior Domain structure

Flow Rate Measurement of Gravity Infusion Set and Functional Evaluation of Drop Counter: A Pilot Study

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Journal of Biomedical Science and Engineering 2024年第7期17卷 129-135页

作者： Rina Sakai Shuichi Tanaka Kaya murakami Tomomi Mizuhashi Kazuhiro Yoshida Masanobu Ujihira Department of Medical Engineering and Technology Kitasato University School of Allied Health Sciences Sagamihara Japan Faculty of Medical Engineering Gunma University of Health and Welfare Maebashi Japan Kitasato University Graduate School of Medical Sciences Sagamihara Japan

Developing a novel drop counter by introducing the Internet of Things concept has been vigorously conducted in recent years. Understanding the newly introduced drop counter’s flow rate control accuracy and flow rate count feature is essential for improving safety in infusion management. This study aimed to verify if the new drop counters could secure accurate flow rate and drip count by conducting actual flow rate measurements using gravimetry and functional evaluation. A drop counter was attached to each drip chamber of the infusion set, and an IV drip was conducted at the 100 ml/h flow rate. The weight of discharged physiological saline was measured to plot trumpet curves. Next, three different types of drop counters were evaluated to determine if they maintained drip count accuracy according to the changes in their position angles. The flow rate errors in all conditions indicated trumpet-like curves, exhibiting an overall error range within ±10% in all observation windows. Although every drop counter successfully detected and measured dripping, it was challenging in some counters to detect dripping when the drip chamber was tilted. In comparing adult and pediatric IV sets, the adult IV set was found to be less likely to detect dripping in the angled position. No significant differences in results were confirmed between high and low flow rates, suggesting that the drop count function would not be affected by the flow rate in the ranges of typical infusion practices. Doppler sensors have a wide range of measurements and high sensitivity;the dripping was detected successfully even when the drip chamber was tilted, probably due to the advantages of these sensors. In contrast, miscounts occurred in those equipped with infrared sensors, which could not detect light intensity changes in tilted positions. Understanding the tendencies in flow rate errors in infusion can be valuable information for infusion management.

关键词： Gravity Infusion Set Drop Counter IV Fluids Flow Rate Trumpet Curves

Study on Distribution of Four Pseudomonas Species in Living Environment Using Multiplex PCR

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Open Journal of Stomatology 2024年第2期14卷 77-86页

作者： Sachiyo Hayashi Koji Umezawa Osamu Tsuzukibashi Akira Fukatsu Mana Fuchigami Chiaki Komine Hiroshi Yamamoto Mio Hagiwara-Hamano Yukiko Iizuka Satoshi Uchibori Masanobu Wakami Hiroshi murakami Taira Kobayashi Masahiko Fukumoto Takato Nomoto Department of Special Needs Dentistry Nihon University School of Dentistry at Matsudo Chiba Japan Department of Laboratory Medicine for Dentistry for the Compromised Patient Nihon University School of Dentistry at Matsudo Chiba Japan Department of Oral Surgery Nihon University School of Dentistry at Matsudo Chiba Japan Department of Fixed Prosthodontics Nihon University School of Dentistry at Matsudo Chiba Japan Department of Oral Implantology Nihon University School of Dentistry at Matsudo Chiba Japan

Purpose: The genus Pseudomonas is a ubiquitous microorganism frequently detected from immunocompromised patients. The inherent resistance to numerous antimicrobial agents contributes to the opportunistic character of this pathogen exhaustive monitoring of this pathogen is considered of critical importance to public health organizations. The reliable identification method able to distinguish genetic close Pseudomonas species is needed, because these organisms are difficult to differentiate by phenotypic or biochemical methods. The purpose of the present study was to design species-specific primers in order to identify and detect four Pseudomonas species which are frequently detected from the human oral cavities, and to investigate the distribution of these organisms in the living environment using a multiplex PCR. Methods: Polymerase chain reaction (PCR) primers were designed based on partial sequences of the rpoD gene of four Pseudomonas species. Swab samples were collected from fifty washstands, and the distribution of Pseudomonas species was investigated using a conventional PCR at genus level and a multiplex PCR at species level. Results: Multiplex PCR method developed in this study was able to distinguish four Pseudomonas species clearly. The genus Pseudomonas was detected from all samples (100%), whereas P. putida, P, aeruginosa, P. stutzeri and P. fluorescens were detected at 44%, 8%, 4% and 2% in fifty swab samples, respectively. Conclusion: Our developed one-step multiplex PCR method is accurate, specific, cost-effective, time-saving, and works without requiring DNA extraction. It was indicated that washstands were the uninhabitable environment for P. putida, P, aeruginosa, P. stutzeri and P. fluorescens.

关键词： Genus Pseudomonas Multiplex PCR Living Environment

Laparoscopic duodenojejunostomy for malignant stenosis as a part of multimodal therapy:A case report

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World Journal of Clinical Cases 2022年第16期10卷 5324-5330页

作者： Teppei murakami Yugo Matsui Department of Surgery Kobe City Hospital Organization Kobe City Center West HospitalKobe 653-0013HyogoJapan

BACKGROUND Laparoscopic duodenojejunostomy(LDJ) has become the standard surgical procedure for superior mesenteric artery syndrome due to its sufficient outcome in terms of safety and symptom relief. However, there are only a few reports about LDJ for malignant stenosis and its indication remains *** SUMMARY A 77-year-old woman with a history of pancreatic cancer(PC) treated with distal pancreatectomy with en bloc resection of the transverse colon 7 mo ago was admitted for recurrent vomiting. Imaging upon admission revealed marked distention of the duodenum and a tumor around the duodenojejunal flexure. She was diagnosed with malignant stenosis caused by local recurrence of PC. LDJ was performed with an uneventful postoperative course, followed by chemotherapy which gave her 10 mo overall *** We think that LDJ is a valuable method for unresectable malignant stenosis around the duodenojejunal flexure as a part of multimodal therapy.

关键词： Duodenojejunostomy Laparoscopic surgery Malignant stenosis Pancreatic cancer Multimodal therapy

Chronic heat stress induces renal fibrosis and mitochondrial dysfunction in laying hens

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畜牧与生物技术杂志:英文版 2023年第5期14卷 2002-2011页

作者： Fumika Nanto‑Hara Makoto Yamazaki Hitoshi murakami Haruhiko Ohtsu Division of Meat Animal and Poultry Research Institute of Livestock and Grassland ScienceNational Agriculture and Food Research Organization(NILGS)2 IkenodaiTsukubaIbaraki 305‑0901Japan

Background Heat stress in laying hens negatively affects egg production and shell quality by disrupting the homeo-stasis of plasma calcium and phosphorus *** the kidney plays an important role in calcium and phos-phorus homeostasis,evidence regarding the effect of heat stress on renal injury in laying hens is yet to be ***,the aim of this study was to evaluate the effects of chronic heat stress on renal damage in hens during laying *** A total of 16 white-leghorn laying hens(32 weeks old)were randomly assigned to two groups(n=8).One group was exposed to chronic heat stress(33°C for 4 weeks),whereas the other group was maintained at 24°*** Chronic heat exposure significantly increased plasma creatinine and decreased plasma albumin levels(P<0.05).Heat exposure also increased renal fibrosis and the transcription levels of fibrosis-related genes(COLA1A1,αSMA,and TGF-β)in the *** results suggest that renal failure and fibrosis were induced by chronic heat exposure in laying *** addition,chronic heat exposure decreased ATP levels and mitochondrial DNA copy number(mtDNA-CN)in renal tissue,suggesting that renal mitochondrial dysfunction occurs under conditions of heat *** mitochondria leak mtDNAs into the cytosol and mtDNA leakage may activate the cyclic GMP-AMP synthase(cGAS)stimulator of interferon genes(STING)signaling *** results showed that chronic heat exposure activated the cGAS-STING pathway as indicated by increased expression of MDA5,STING,IRF7,MAVS,and NF-κB ***,the expression of pro-inflammatory cytokines(IL-12)and chemokines(CCL4 and CCL20)was upregulated in heat-stressed *** These results suggest that chronic heat exposure induces renal fibrosis and mitochondrial damage in laying *** damage by heat stress may activate the mtDNA-cGAS-STING signaling and cause subse-quent inflammation,which contributes to the progression of renal fibrosis and

关键词： cGAS-STING Heat stress Laying hens Mitochondrial DNA Renal fibrosis

Laser-driven electrodynamic implosion of fast ions in a thin shell

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Matter and Radiation at Extremes 2023年第5期8卷 73-81页

作者： S.Yu.Gus’kov Ph.Korneev M.murakami P.N.Lebedev Physical Institute of Russian Academy of Sciences 53 Leninskii Prospect119991 MoscowRussian Federation Institute of Laser Engineering Osaka University565-0871 OsakaJapan

Collision of laser-driven subrelativistic high-density ion flows provides a way to create extremely compressed ion conglomerates and study their *** paper presents a theoretical study of the electrodynamic implosion of ions inside a hollow spherical or cylindrical shell irradiated by femtosecond petawatt laser *** propose to apply a very effective mechanism for ion acceleration in a self-consistent field with strong charge separation,based on the oscillation of laser-accelerated fast electrons in this field near the thin *** electrons are generated on the outer side of the shell under irradiation by the intense laser *** is shown that ions,in particular protons,may be accelerated at the implosion stage to energies of tens and hundreds of MeV when a sub-micrometer shell is irradiated by femtosecond laser pulses with an intensity of 10^(21)–10^(23)W cm^(−2).

关键词： dynamic thin irradiated

Disease trends after Helicobacter pylori eradication based on Japanese nationwide claims and the health check-up database

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World Journal of Gastroenterology 2023年第4期29卷 692-705页

作者： Kazuhiro Mizukami Kentaro Sugano Tomomi Takeshima Kazunari murakami Department of Gastroenterology Oita UniversityOita 8795593Japan Department of Medicine Jichi Medical UniversityTochigi 3290498Japan Milliman Inc. Tokyo 1020083Japan

BACKGROUND Helicobacter pylori(***)infection is a risk factor for many diseases,including peptic ulcer disease and gastric *** *** eradication therapy can prevent these diseases,potentially unfavorable effects of eradication therapy have also been reported in some diseases,such as gastroesophageal reflux disease(GERD),Barrett’s esophagus(BE),inflammatory bowel disease(IBD),allergic diseases,and metabolic ***,both positive and negative impacts should be considered when assessing the effects of *** eradication *** To compare the incidence of these diseases before and after *** eradication and to comprehensively assess its *** This retrospective cohort study used a Japanese nationwide health claims database(April 2009-March 2020),developed by the Japanese Ministry of Health,Labour and *** database contained almost all health insurance claims data issued in Japan,and specific health check-up data for individuals who took the *** statistics were used for the *** who received primary eradication therapy were defined as those prescribed medication for *** *** diagnoses,defined as incidence of upper gastrointestinal diseases and IBD,and prevalence of allergic diseases were compared before and after *** incidence and prevalence of each disease were also compared between the 3-year period before eradication(from the 4th to the 2nd year prior to the year of eradication)and the 3-year period after eradication(from the 1st to the 3rd year after the year of eradication)based on the age category and calendar year and *** in body mass index and proportion of patients with metabolic syndrome(MS)were examined before and after *** We identified 5219731 patients who received primary eradication *** 65-69 years age group had the greatest number of patients in both *** was no significant increase in the incidence

关键词： Administrative claims Healthcare Allergy Eradication therapy Gastroesophageal reflux disease Helicobacter pylori Inflammatory bowel disease

COVID-19 vaccination and liver disease

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World Journal of Gastroenterology 2022年第48期28卷 6791-6810页

作者： Sotaro Ozaka Takashi Kobayashi Kazuhiro Mizukami Kazunari murakami Department of Gastroenterology Faculty of MedicineOita UniversityYufu 879-5593OitaJapan Department of Infectious Disease Control Faculty of MedicineOita UniversityYufu 879-5593OitaJapan

Various vaccines against severe acute respiratory syndrome coronavirus 2 have been developed in response to the coronavirus disease 2019(COVID-19)global pandemic,several of which are highly effective in preventing COVID-19 in the general *** with chronic liver diseases(CLDs),particularly those with liver cirrhosis,are considered to be at a high risk for severe COVID-19 and *** the increased rates of disease severity and mortality in patients with liver disease,there is an urgent need to understand the efficacy of vaccination in this ***,the data regarding efficacy and safety of COVID-19 vaccination in patients with CLDs is ***,several organ-specific or systemic immune-mediated side effects following COVID-19 vaccination,including liver injury similar to autoimmune hepatitis,have been recently *** the number of cases of vaccine-related liver injury is increasing,its frequency,clinical course,and mechanism remain ***,we review the current findings on COVID-19 vaccination and liver disease,focusing on:(1)The impact of COVID-19 in patients with CLD;(2)The efficacy,safety,and risk-benefit profiles of COVID-19 vaccines in patients with CLD;and(3)Liver injury following COVID-19 vaccination.

关键词： COVID-19 vaccine Liver disease Side effect Liver injury Immune-related hepatitis Autoimmune hepatitis