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Characterization of focal hypermetabolic thyroid incidentaloma: An analysis with F-18 fluorodeoxyglucose positron emission tomography/computed tomography parameters

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World Journal of Clinical Cases 2022年第1期10卷 155-165页

作者： Haejun lee Yoo Seung Chung Joon-Hyop lee ki-young lee Kyung-Hoon Hwang Department of Nuclear Medicine Gachon University College of MedicineGil Medical CenterIncheon 21565South Korea Department of Endocrine Surgery Gachon University College of MedicineGil Medical CenterIncheon 21565South Korea Department of Endocrinology and Metabolism Gachon University College of MedicineGil Medical CenterIncheon 21565South Korea

BACKGROUND Incidentally found thyroid tumor(thyroid incidentaloma,TI)on F-18 fluorodeoxyglucose(FDG)positron emission tomography-computed tomography(PETCT)is reported in 2.5%-5%of patients being investigated for non-thyroid *** to 50%of these cases have been diagnosed to be malignant by cytological/histological ***(US)and fine-needle aspiration cytology are recommended for thyroid nodules with high FDG uptake(hypermetabolism)that are 1 cm or greater in *** is important to accurately determine whether a suspicious hypermetabolic TI is malignant or *** To distinguish malignant hypermetabolic TIs from benign disease by analyzing F-18 FDG PET-CT parameters and to identify a cut-off *** Totally,12761 images of patients who underwent F-18 FDG PET-CT for nonthyroid purposes at our hospital between January 2016 and December 2020 were retrospectively reviewed,and 339 patients[185 men(mean age:68±11.2)and 154 women(mean age:63±15.0)]were found to have abnormal,either focal or diffuse,thyroid FDG *** a thorough review of their medical records,US,and cytological/histological reports,46 eligible patients with focal hypermetabolic TI were included in this *** TIs were categorized as malignant and benign according to the cytological/histological reports,and four PET parameters[standardized uptake value(SUV)max,SUV_(peak),SUV_(mean),and metabolic tumor volume(MTV)]were measured on FDG *** lesion glycolysis(TLG)was calculated by multiplying the SUV_(mean) by *** parametric and non-parametric methods were used to compare the five parameters between malignant and benign *** operating characteristic(ROC)curve analysis was performed to identify a cut-off *** Each of the 46 patients[12 men(26.1%;mean age:62±13.1 years)and 34 women(73.9%;mean age:60±12.0 years)]with focal hypermetabolic TIs had one focal hypermetabolic *** them,26(56.5%)were malignant and 20(43.5%)were ***_(max

关键词： Thyroid incidentaloma Malignancy Fluorodeoxyglucose positron emission tomography/computed tomography Standardized uptake value Cut-off

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A Study of the Vortical Flow over a Delta Wing with a Leading Edge Extension

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Journal of Thermal Science 2003年第4期12卷 299-303页

作者： Heuy-Dong kim young-ki lee Tae-Ho kim Myoung-Hwan Sohn School of Mechanical Engineering Andong National University Andong 760-749 KoreaSchool of Mechanical Engineering Andong National University Andong 760-749 KoreaSchool of Mechanical Engineering Andong National University Andong 760-749 KoreaDepartment of Aerospace Engineering Korean Air Force Academy Chongwon-gun ChungBook-Do 363-849 Korea

The present paper describes computational and experimental work on the vortex flow characteristics of a sharp-edged delta wing with a leading edge extension (LEX). Experiment was carried out using a low-speed wind tunnel that has a test section of 3.5 m(W)×2.45 m(H)×8.7 m(L). The angle of attack of the delta wing ranges from 10° to 30°. The free stream velocity is fixed at 20 m/s, which corresponds to Reynolds number of 0.88×106. Computations using the mass-averaged implicit 3D Navier-Stokes equations were applied to predict the complicated vortical flow over the delta wing. The governing equations were discretized in space using a fully implicit finite volume differencing formation. The standard k-e turbulent model was employed to close the governing equations. The present computations predicted the experimented flow field with a good accuracy.

关键词： delta wing leading edge extension (LEX) vortex core vortex strength.

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The SARS-CoV-2 spike protein induces lung cancer migration and invasion in a TLR2-dependent manner

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Cancer Communications 2024年第2期44卷 273-277页

作者： Mi-Jeong kim Ji young kim Ji Hye Shin Juhee Son Yeeun Kang Soo-Kyung Jeong Duk-Hwan kim Kyun-Hwan kim Eunyoung Chun ki-young lee Department of Immunology Samsung Biomedical Research InstituteSungkyunkwan University School of MedicineSuwonRepublic of Korea Research and Development Center CHA Vaccine InstituteSeongnam-siRepublic of Korea Department of Molecular Cell Biology Sungkyunkwan University School of MedicineSuwonRepublic of Korea Department of Precision Medicine Sungkyunkwan University School of MedicineSuwonRepublic of Korea Department of Health Sciences and Technology Samsung Advanced Institute for Health Sciences&TechnologySamsung Medical CenterSungkyunkwan UniversitySeoulRepublic of Korea

Dear editor,Severe acute respiratory syndrome coronavirus2(SARS-CoV-2)infection can lead to severe outcomes in patients with cancer[1].It has been reported that patients with lung cancers disproportionately manifest severe COVID-19 with a high rate of hospitalization and death[2].Notably,the SARS-CoV-2 Spike(S)protein can induce hyper-inflammation in both epithelial cells and macrophages through toll-like receptor(TLR)1/TLR2 or TLR2/6-dependent nuclear factor-kappaB(NF-κB)path-way[3].However,molecular and cellular evidence on whether the SARS-CoV-2 virus affects the severity of lung cancer patients through TLR1/2 or TLR2/6 signaling remains unclear.

关键词： lung TLR2 invasion

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Gametogenic Cycle, the Spawning Season, First Sexual Maturity, and the Biological Minimum Size in Male Ruditapes philippinarum （Bivalvia： Veneridae） in Western Korea

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Journal of Life Sciences 2013年第6期7卷 613-622页

作者： Ee-Yung Chung Jae Seung Chung ki-young lee Department of Marine Biotechnology Kunsan National University Gunsan 5 73- 701 Korea Department of Urology College of Medicine Inje University Busan 614-735 Korea

The male gametogenic cycle, spawning season, first sexual maturity, and the biological minimum size in male Ruditapes philippinarum were investigated by qualitative and quantitative reproductive analyses. In the study of the male gametogenic cycle by qualitative histological analysis, the gametogenic cycle in male individuals can be classified into five successive stages：（1） early active stage, （2） late active stage, （3） ripe stage, （4） partially spawned stage, and （5） spent and inactive stage. Monthly changes in the gonad index in males measured by qualitative analysis showed a similar pattern to the male gametogenic cycle. In the study of the male gametogenic cycle by quantitative statistical analysis, monthly changes in the portions （%） of areas occupied by the testis areas to total tissue areas showed a rapid increase in March, and reached the maximum in May-June. And also monthly changes in the portions （%） of areas occupied by the spermatogenic stages to the testis area showed a maximum in May and gradually decreased from June to October. Therefore, this species showed a unimodal gametogenic cycle during the year, and the number of spawning seasons occurred once per year, from June to October, with a peak spawning between July and August. The percentage at the first sexual maturity of male clams ranging from 15.1-20.0 mm in shell length was 64.7%, and that of all individuals ranging from over 25.1 mm in shell length was 100%. The biological minimum size （shell lengths at 50% of sexual maturity （RMs0）） of male mature clams that was fitted to an exponential equation was 17.16 mm （considered to be 1 year old）. Because harvesting clams less than 17.16 mm in shell length could potentially cause a drastic reduction in recruitment, a measure indicating a prohibitory fishing size should be enacted for adequate fisheries management.

关键词： Male Ruditapes philippinarum gametogenic cycle spawning season first sexual maturity biological minimum size.

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Parametric Study of Sulfur Trioxide Decomposer in a Small-Scale Test Loop Facility

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Journal of Chemistry and Chemical Engineering 2011年第10期5卷 890-896页

作者： Jong-Ho kim ki-young lee Yong-Wan kim Korea Atomic Energy Research Institute Republic of Korea

A High Temperature Gas Cooled Reactor （HTGR） with an outlet coolant temperature of 950 ℃ is considered as an efficient reactor to couple with the thermo-chemical Sulfur Iodine （SI） cycle for a hydrogen production. The test loop was installed in the Korea Atomic Energy Research Institute （KAERI） facility to confirm the integrity of the sulfur trioxide decomposer, one of the key components in the test loop, under HTGR operating conditions. In this paper, the simulation using Aspen plus, a chemical process simulator, was made to evaluate the performance of a sulfur trioxide decomposer. The simulation indicated that at least 10 kW heat needs to be supplied to the sulfur trioxide decomposer in the test loop when the sulfuric acid flowrate is 0.5 kg/min. The simulation flowsheet was obtained and the material balance around the sulfur trioxide decomposer was determined in case of 10 kW heat input and 0.5 kg/min flowrate of liquid sulfuric acid. The parametric study was carried out for sulfur trioxide decomposer. It indicated that the moles of sulfur dioxide produced at the decomposer increases as the operating temperature increases and is decreasing as the operating pressure becomes higher at a given temperature. The parametric study also indicated water vapor removal out of the decomposer is a less effective method to increase the sulfur trioxide conversion ratio.

关键词： SI cycle hydrogen production sulfur trioxide decomposer test loop

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High Concentration of Calcium in Hypotonic Solution is Suppressive to Bacterial Wilt of Tomato,and Calcium Reduces the Activity of Polygalactronase secreted by Ralstonia solanacearum

High Concentration of Calcium in Hypotonic Solution is Suppr...

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中国植物病理学会2011年学术年会

作者： Inn-Shik Myung young-ki lee Hongsik Shim Crop Protection National Academy of Agricultural ScienceRural Development AdministrationSuwon 441-707Korea

The effects of calcium concentration in nutrient solution on the development of bacterial wilt of tomato,and on the activity of polygalaturonase secreted by Ralstonia solancearum were *** seedlings cultivated in nutrient solutions containing different calcium concentrations were inoculated using root inoculation method with 50ml of bacterial suspension(1×10 cfu/ml) with sterile-distilled water in a *** confirmed that

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复合应用利多卡因对鞘内注射布比卡因时效的影响

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麻醉与镇痛 2010年第1期6卷 16-19页

作者： Sung-Jin lee Sun-Joon Bai Jong-Seok lee Won-Ok kim Yang-Sik Shin ki-young lee 邹蓉(译) 崔苏扬(校) Department of Anesthesiology and Pain Medicine Anesthesia and Pain Research Institute Yonsei University College of Medicine Seoul Korea 不详

背景由于阻滞持续时间较长，布比卡因蛛网膜下腔阻滞技术在门诊手术中使用受限。近期动物研究结果证实复合利多卡因后能缩短布比卡因蛛网膜下腔阻滞的持续时间。我们的研究旨在证实人类蛛网膜下腔阻滞时布比卡因复合利多卡因是否如同动... 详细信息

背景由于阻滞持续时间较长，布比卡因蛛网膜下腔阻滞技术在门诊手术中使用受限。近期动物研究结果证实复合利多卡因后能缩短布比卡因蛛网膜下腔阻滞的持续时间。我们的研究旨在证实人类蛛网膜下腔阻滞时布比卡因复合利多卡因是否如同动物实验结果一样能够缩短其阻滞时间。方法采用随机双盲的方法将90例纳入本项研究的经尿道行膀胱肿瘤切除或前列腺切除的患者分为3组。每组均鞘内注射0．5％布比卡因重比重液1．5ml及下述溶液0．6ml：组Ⅰ（30例，对照组）生理盐水，组Ⅱ（30例）1％利多卡因，组Ⅲ（30侧）2％利多卡因。记录感觉阻滞最高平面、达到感觉阻滞最高平面的时间、从感觉阻滞最高平面到消退两个节段以及消退至L1和S2平面的时间、在感觉阻滞最高平面时和平面消退至L1和S2时的运动阻滞评分及在麻醉恢复室（PACU）的留观时间。结果3组患者达到感觉阻滞最高平面的时间相似。组Ⅱ患者的感觉阻滞最高平面消退两个节段和消退至L1和S2水平的时间，以及PACU内留观时间均较组Ⅰ患者显著缩短。组Ⅲ患者的感觉阻滞最高平面消退至L1和S2水平的时间，以及PACU内留观时间均显著延长。结论复合使用利多卡因（6mg）能够缩短布比卡因（7．5mg）的蛛网膜下腔阻滞时间，阻滞后患者恢复程度较单独使用相同剂量布比卡因（7．5mg）的脊髓麻醉更加迅速。

关键词： 1%利多卡因布比卡因复合应用鞘内注射蛛网膜下腔阻滞感觉阻滞时效膀胱肿瘤切除

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A Rapid Adaptation Approach for Dynamic Air‑Writing Recognition Using Wearable Wristbands with Self‑Supervised Contrastive Learning

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Nano-Micro Letters 2025年第2期17卷 417-431页

作者： Yunjian Guo Kunpeng Li Wei Yue Nam‑young kim Yang Li Guozhen Shen Jong‑Chul lee Department of Electronic Convergence Engineering Kwangwoon UniversitySeoul 01897South Korea Radio Frequency Integrated Circuit(RFIC)Bio Centre Kwangwoon UniversitySeoul 01897South Korea Department of Electronic Engineering Kwangwoon UniversitySeoul 01897South Korea School of Microelectronics Shandong UniversityJinan 250101People’s Republic of China State Key Laboratory of Integrated Chips and Systems Fudan UniversityShanghai 200433People’s Republic of China School of Integrated Circuits and Electronics Beijing Institute of TechnologyBeijing 100081People’s Republic of China

Wearable wristband systems leverage deep learning to revolutionize hand gesture recognition in daily *** existing approaches that often focus on static gestures and require extensive labeled data,the proposed wearable wristband with selfsupervised contrastive learning excels at dynamic motion tracking and adapts rapidly across multiple *** features a four-channel sensing array composed of an ionic hydrogel with hierarchical microcone structures and ultrathin flexible electrodes,resulting in high-sensitivity capacitance *** wireless transmission from a Wi-Fi module,the proposed algorithm learns latent features from the unlabeled signals of random wrist ***,only few-shot labeled data are sufficient for fine-tuning the model,enabling rapid adaptation to various *** system achieves a high accuracy of 94.9%in different scenarios,including the prediction of eight-direction commands,and air-writing of all numbers and *** proposed method facilitates smooth transitions between multiple tasks without the need for modifying the structure or undergoing extensive task-specific *** utility has been further extended to enhance human–machine interaction over digital platforms,such as game controls,calculators,and three-language login systems,offering users a natural and intuitive way of communication.

关键词： Wearable wristband Self-supervised contrastive learning Dynamic gesture Air-writing Human-machine interaction

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Pan-TRK positive uterine sarcoma in immunohistochemistry without neurotrophic tyrosine receptor kinase gene fusions:A case report

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World Journal of Clinical Cases 2025年第2期13卷 39-49页

作者： Seungmee lee Yu-Ra Jeon Changmin Shin Sun-young Kwon Sojin Shin Department of Obstetrics and Gynecology Keimyung University School of MedicineDaegu 42601South Korea Department of Pathology and Institute for Cancer Research Keimyung University School of MedicineDaegu 42601South Korea

BACKGROUND The classification of uterine sarcomas is based on distinctive morphological and immunophenotypic characteristics,increasingly supported by molecular genetic *** on neurotrophic tyrosine receptor kinase(NTRK)gene fusionpositive uterine sarcoma,potentially aggressive and morphologically similar to fibrosarcoma,are limited due to its recent ***-TRK immunohistochemistry(IHC)analysis serves as an effective screening tool with high sensitivity and specificity for NTRK-fusion *** SUMMARY We report a case of a malignant mesenchymal tumor originating from the uterine cervix,which was pan-TRK IHC-positive but lacked NTRK gene fusions,accompanied by a brief literature review.A 55-year-old woman presented to the emergency department with abdominal pain and distension,exhibiting significant ascites and multiple solid pelvic *** examination revealed a tumor encompassing the uterine cervix,extending to the vagina and uterine corpus.A punch biopsy of the cervix indicated NTRK sarcoma with positive immunochemical pan-TRK ***,subsequent next generation sequencing revealed no NTRK gene fusion,leading to a diagnosis of poorly differentiated,advanced-stage *** The clinical significance of NTRK gene fusion lies in potential treatment with TRK inhibitors for positive *** such rare tumors is crucial due to the potential applicability of tropomyosin receptor kinase inhibitor treatment.

关键词： Uterine sarcoma Cervical sarcoma Neurotrophic tyrosine receptor kinase gene fusion Next generation sequencing Case report

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A New Encryption Mechanism Supporting the Update of Encrypted Data for Secure and Efficient Collaboration in the Cloud Environment

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Computer Modeling in Engineering & Sciences 2025年第1期142卷 813-834页

作者： Chanhyeong Cho Byeori kim Haehyun Cho Taek-young Youn Department of Cyber Security Dankook UniversityYongin16890Republic of Korea Department of Software Soongsil UniversitySeoul07027Republic of Korea

With the rise of remote collaboration,the demand for advanced storage and collaboration tools has rapidly ***,traditional collaboration tools primarily rely on access control,leaving data stored on cloud servers vulnerable due to insufficient *** paper introduces a novel mechanism that encrypts data in‘bundle’units,designed to meet the dual requirements of efficiency and security for frequently updated collaborative *** bundle includes updated information,allowing only the updated portions to be reencrypted when changes *** encryption method proposed in this paper addresses the inefficiencies of traditional encryption modes,such as Cipher Block Chaining(CBC)and Counter(CTR),which require decrypting and re-encrypting the entire dataset whenever updates *** proposed method leverages update-specific information embedded within data bundles and metadata that maps the relationship between these bundles and the plaintext *** utilizing this information,the method accurately identifies the modified portions and applies algorithms to selectively re-encrypt only those *** approach significantly enhances the efficiency of data updates while maintaining high performance,particularly in large-scale data *** validate this approach,we conducted experiments measuring execution time as both the size of the modified data and the total dataset size *** show that the proposed method significantly outperforms CBC and CTR modes in execution speed,with greater performance gains as data size ***,our security evaluation confirms that this method provides robust protection against both passive and active attacks.

关键词： Cloud collaboration mode of operation data update efficiency

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