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External defects and severity level evaluation of potato using single and multispectral imaging in near infrared region Author links open overlay panel

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Information Processing in Agriculture 2024年第1期11卷 80-90页

作者： Dimas Firmanda Al Riza Slamet Widodo kazuya yamamoto Kazunori Ninomiya Tetsuhito Suzuki Yuichi Ogawa Naoshi Kondo Laboratory of Biosensing Engineering Graduate School of AgricultureKyoto UniversityKitashirakawaKyoto 6068267Japan Department of Biosystems Engineering Faculty of Agricultural TechnologyUniversitas BrawijayaJl.VeteranMalang 65145Indonesia Department of Mechanical and Biosystem Engineering Bogor Agricultural UniversityJl.Raya Darmaga Kampus IPB DarmagaBogor 16680Indonesia Technology Development Department Shibuya Seiki Co.Ltd.66Takaoka-choMatsuyamaEhime 7918036Japan

Non-invasive potato defects detection has been demanded for sorting and grading *** on the classification of the defects has been available,however,investigation on the severity level calculation is *** the detection of the common scab,it has been found that imaging in the infrared region provide an interesting characteristic that could distinguish defected area to normal ***,investigations on this wavelength range is interesting to add more knowledge and for *** this research,the multispectral image has been obtained and investigated especially at three wavelengths(950,1150,1600 nm).Image pre-processing and pseudo-color conversion techniques were explored to enhance the contrast between defects,normal background skin area and soil *** show that external defects,such as common scab and some mechanical damage types,appear brighter in the near infrared region,especially at 1600 nm against the normal skin *** has been found that pseudo-color images conversion provides more information regarding type if surface characteristics compared to grayscale single *** segmentation using pseudo-color images after multiplication operation pre-processing could be used for common scab and mechanical damage detection excluding soil deposits with a Dice Sorensen coefficient of *** addition,image segmentation using single image at 1600 nm shown relatively better results with Dice Sorensen coefficient of 0.72 with note that thick soil deposits will also be *** severity level evaluation had an R2 correlation of 0.84 against standard measurements of severity.

关键词： Multispectral imaging Pseudo-color Common scab External defects Near infrared

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Photo-Induced Reduction Reaction of Methylene Blue in an Ionic Liquid

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International Journal of Organic Chemistry 2011年第4期1卷 158-161页

作者： Jun-ichi Kadokawa Hironori Izawa Tomoya Ohta Satoshi Wakizono kazuya yamamoto Graduate School of Science and Engineering Kagoshima University

Reduction of methylene blue (MB) occurred by photo irradiation at 280 - 370 nm wavelengths to a solution of MB in an ionic liquid, 1-butyl-3-methylimidazolium chloride (BMIMCl), which was confirmed by color change and UV-Vis measurement of the solution. Furthermore, the reduced MB was oxidized again by standing the solution under the conditions of light shielding at 50?C. The fluorescence spectra of the solution excited at 350 nm suggested that the photo-induced reduction probably took place via electron-transfer from BMIMCl to MB.

关键词： Methylene Blue Ionic Liquid Reduction Photo Irradiation

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Photo-Induced Reduction Reaction of Methylene Blue in an Ionic Liquid

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International Journal of Organic Chemistry 2011年第4期

作者： Jun-ichi Kadokawa Hironori Izawa Tomoya Ohta Satoshi Wakizono kazuya yamamoto

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Lifecycle Evaluation of Base-Isolated Rubber Bearings Considering Environmental Deterioration

Lifecycle Evaluation of Base-Isolated Rubber Bearings Consid...

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国际桥梁2004年大会

作者： kazuya SATOH Yoshito ITOH Akio YAZAWA Yoshihisa yamamoto Student of Civil Engineer Nagoya University Aichi Japan Professor Nagoya University Aichi Japan Student of Civil Engineer Nagoya University Aichi Japan Section Chief Tokai Rubber Industry Aichi Japan

＜正＞ 1. IntroductionIn Japan, the base-isolated seismic design has been adopted widely after Hyogoken-Nanbu Earthquake in 1995. Specifically, the base-isolated rubber bearings are widely used, and further demand is expected in the atomic power plants, buildings, and civil structures. However, long-term deterioration characteristics of base-isolated rubber bearings have not yet been known. The reason for this is that there are little basic data of deterioration characteristics of them. So, it is unknown that mechanical performances of the deteriorated base-isolated rubber bearings. This problem should be solved because long-life structures are required.

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Prognostic Significance of Hematologic Markers in Patients with Head and Neck Squamous Cell Carcinomas

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International Journal of Otolaryngology and Head & Neck Surgery 2018年第2期7卷 55-65页

作者： Ryohei Oya Yukinori Takenaka Kengo Aoki Hiroko Hamaguchi kazuya Takemura Masayuki Nozawa Takahiro Kitamura Yoshifumi yamamoto Atsuhiko Uno Department of Otorhinolaryngology-Head and Neck Surgery Osaka General Medical Center Osaka Japan Department of Otorhinolaryngology-Head and Neck Surgery Osaka University Graduate School of Medicine Osaka Japan Department of Otorhinolaryngology-Head and Neck Surgery Kansai Medical Hospital Osaka Japan

Aim: To assess the prognostic value of hematologic markers for cancers of the head and neck region, according to tumor site. Methods: We reviewed the data of 441 patients diagnosed with head and neck squamous cell carcinomas (HNSCC) between 2006 and 2014. Overall survival rates were estimated using the Kaplan-Meier method and Cox proportional hazards models were used to assess the hazard ratio (HR) for death, according to hematologic markers. Results: In the univariate analyses, hemoglobin concentration;leukocyte, neutrophil, monocyte, and platelet counts;and the platelet-lymphocyte ratio were associated with overall survival. In the multivariate analyses, hemoglobin concentration (HR 0.55, 95% confidence interval [CI] 0.38 - 0.78, p Conclusions: Several hematologic markers have prognostic significance for patients with HNSCC, however, the magnitude of the effect depends on the tumor site.

关键词： Biomarkers Head and Neck Cancer Hematologic Marker

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Multicenter study of endoscopic preoperative biliary drainage for malignant distal biliary obstruction

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World Journal of Gastroenterology 2016年第14期22卷 3793-3802页

作者： Naoki Sasahira Tsuyoshi Hamada Osamu Togawa Ryuichi yamamoto Tomohisa Iwai Kiichi Tamada Yoshiaki Kawaguchi Kenji Shimura Takero Koike Yu Yoshida kazuya Sugimori Shomei Ryozawa Toshiharu Kakimoto Ko Nishikawa Katsuya Kitamura Tsunao Imamura Masafumi Mizuide Nobuo Toda Iruru Maetani Yuji Sakai Takao Itoi Masatsugu Nagahama Yousuke Nakai Hiroyuki Isayama Department of Gastroenterology JCHO Tokyo Takanawa HospitalTokyo 108-8606Japan Department of Gastroenterology Graduate School of MedicineThe University of TokyoTokyo 113-8655Japan Department of Gastroenterology Saitama International Medical CenterSaitama Medical UniversitySaitama 350-1298Japan Department of Gastroenterology and Hepatology Saitama Medical University International Medical CenterSaitama 350-8550Japan Department of Gastroenterology Kitasato UniversityKanagawa 252-0375Japan Department of Gastroenterology Jichi Medical UniversityTochigi 329-0498Japan Department of Gastroenterology Tokai UniversityKanagawa 259-1193Japan Department of Gastroenterology Asahi General HospitalChiba 289-2511Japan Department of Internal Medicine Japanese Red Cross Ashikaga HospitalTochigi 326-0843Japan Department of Gastroenterology Kimitsu Central HospitalChiba 292-8535Japan Department of Gastroenterology Yokohama City University Medical CenterKanagawa 232-0024Japan Department of Gastroenterology Showa University Northern Yokohama HospitalKanagawa 242-0032Japan Department of Gastroenterology Saitama City HospitalSaitama 336-8522Japan Department of Gastroenterology Ageo Central General HospitalSaitama 362-8588Japan Division of Gastroenterology Department of MedicineShowa University School of MedicineTokyo 142-8666Japan Department of Gastroenterology Toranomon HospitalTokyo 105-0001Japan Department of Gastroenterology Gunma UniversityGunma 371-0034Japan Department of Gastroenterology Mitsui Memorial HospitalTokyo 101-8643Japan Division of Gastroenterology and Hepatology Department of Internal MedicineToho University Ohashi Medical CenterTokyo 153-0044Japan Department of Gastroenterology Chiba UniversityChiba 260-0856Japan Department of Gastroenterology Tokyo Medical UniversityTokyo 160-0023Japan Department of Gastroenterology Showa University Fujigaoka HospitalKanagawa 227-8501Japan

AIM: To determine the optimal method of endoscopic preoperative biliary drainage for malignant distal biliary ***: Multicenter retrospective study was conducted in patients who underwent plastic stent (PS) or nasobiliary catheter (NBC) placement for resectable malignant distal biliary obstruction followed by surgery between January 2010 and March 2012. Procedure-related adverse events, stent/catheter dysfunction (occlusion or migration of PS/NBC, development of cholangitis, or other conditions that required repeat endoscopic biliary intervention), and jaundice resolution (bilirubin level < 3.0 mg/dL) were evaluated. Cumulative incidence of jaundice resolution and dysfunction of PS/NBC were estimated using competing risk analysis. Patient characteristics and preoperative biliary drainage were also evaluated for association with the time to jaundice resolution and PS/NBC dysfunction using competing risk regression ***: In total, 419 patients were included in the study (PS, 253 and NBC, 166). Primary cancers included pancreatic cancer in 194 patients (46%), bile duct cancer in 172 (41%), gallbladder cancer in three (1%), and ampullary cancer in 50 (12%). The median serum total bilirubin was 7.8 mg/dL and 324 patients (77%) had ≥ 3.0 mg/dL. During the median time to surgery of 29 d [interquartile range (IQR), 30-39 d]. PS/NBC dysfunction rate was 35% for PS and 18% for NBC [Subdistribution hazard ratio (SHR) = 4.76; 95%CI: 2.44-10.0, P < 0.001]; the pig-tailed tip was a risk factor for PS dysfunction. Jaundice resolution was achieved in 85% of patients and did not depend on the drainage method (PS or NBC).CONCLUSION: PS has insufficient patency for preoperative biliary drainage. Given the drawbacks of external drainage via NBC, an alternative method of internal drainage should be explored.

关键词： Endoscopic preoperative biliary drainage Malignant distal biliary obstruction Periampullary cancer Plastic stent Nasobiliary drainage

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Efficacy and safety of sofosbuvir and ledipasvir in Japanese patients aged 75 years or over with hepatitis C genotype 1

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World Journal of Hepatology 2017年第36期9卷 1340-1345页

作者： Yoshinori Ozono Kenji Nagata Satoru Hasuike Hisayoshi Iwakiri Kenichi Nakamura Mai Tsuchimochi Yuri Yamada Yuka Takaishi Mitsue Sueta Tadashi Miike Yoshihiro Tahara Shojiro yamamoto Kotaro Shide Tomonori Hidaka Yoko Kubuki Kazunori Kusumoto Toshimasa Ochiai Junya Kato Naoto Komada Shuichi Hirono Kazuo Kuroki Masafumi Shigehira kazuya Shimoda Department of Gastoroenterology and Hematology Faculty of Medicine University of Miyazaki Department of Liver Disease University of Miyazaki Hospital Department of Internal Medicine Koga General Hospital Department of Internal Medicine National Hospital Organization Miyakonojo Medical Center Department of Internal Medicine Hirono Naika Clinic Department of Internal Medicine Kushima Municipal Hospital Department of Internal Medicine Shigehira Clinic

AIM To evaluate the efficacy and safety of a regimen containing sofosbuvir(SOF) and ledipasvir(LDV) in Japanese patients aged ≥ 75 years with hepatitis C genotype *** This multicenter, retrospective study consisted of 246 Japanese patients with HCV genotype 1 at nine centers in Miyazaki prefecture in Japan. Demographic, clinical, virological, and adverse effects(AE)-related data obtained during and after SOF/LDV therapy were collected from medical records. These patients were divided into two groups, younger(aged < 75 years) and elderly(aged ≥ 75 years). Virological data and AEs were analyzed by age *** The sustained virological response(SVR) rates at 12 wk after treatment were 99.2%, 99.4%, and 98.7% in the overall population and in patients aged < 75 and ≥ 75 years, respectively. Common AEs during therapy were headache, pruritus, constipation, and insomnia. These occurred in fewer than 10% of patients, and their incidence was not significantly different between the younger and elderly groups. Two patients discontinued treatment, one due to a skin eruption and the other due to cerebral bleeding. CONCLUSION Compared with younger patients, elderly patients had a similar virological response and tolerance to SOF/LDV therapy.

关键词： Chronic hepatitis C Sofosbuvir Ledipasvir Sustained virological response Direct acting antivirals

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Radiotherapy for multiple brain metastases from hepatocellular carcinomas

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World Journal of Gastroenterology 2007年第33期13卷 4520-4522页

作者： Nobuyuki Toshikuni Kazuhiko Morii Michinori yamamoto Department of Internal Medicine Center for Liver Diseases Kawasaki Hospital Kawasaki Medical SchoolOkayama Japan Department of Internal Medicine Himeji RedCross Hospital Himeji Japan Department of Internal Medicine Himeji Red Cross Hospital Himeji Japan Department of Radiology Himeji Red Cross Hospital Himeji Japan

A 78-year-old man with liver cirrhosis was found to have multiple hepatocellular carcinomas （HCCs） and underwent 3 sessions of transcatheter arterial chernoernbolization. Fourteen months after diagnosis, the patient presented with left herniparesis. Contrast- enhanced magnetic resonance imaging showed multiple metastases with ring-shaped enhancement in the cerebrum and cerebellum. There were no metastases to other organs. The metastatic lesions almost completely disappeared after whole-brain radiotherapy with a total dose of 50 Gy. Neurologic symptoms decreased, and the patient＇s quality of life improved. The patient underwent 2 more sessions of transcatheter arterial chemoembolization. Twelve months after the diagnosis of brain metastasis, the patient remains alive. The present case indicates that radiotherapy can improve quality of life and prolong survival in some patients with brain metastases from HCCs.

关键词： Hepatocellular carcinoma Brain metastasis Radiotherapy

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FREE SOFTWARE TOOLKIT FOR JAPANESE LARGE VOCABULARY CONTINUOUS SPEECH RECOGNITION

FREE SOFTWARE TOOLKIT FOR JAPANESE LARGE VOCABULARY CONTINUO...

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6～(th) International Conference on Spoken Language Processing

作者： Tatsuya Kawahara Akinobu Lee Tetsunori Kobayashi kazuya Takeda Nobuaki Minematsu Shigeki Sagayama Katsunobu Itou Akinori Ito Mikio yamamoto Atsushi Yamada Takehito Utsuro Kiyohiro Shikano School of Informatics. Kyoto University 606-8501. Japan Kyoto Univ Waseda Univ Nagoya Univ Tokyo Univ Tokyo Univ ETL Yamagata Univ Tsukuba Univ ASTEM Toyohashi Univ. Tech Nara Inst. of Sci. ＆ Tech

＜正＞A sharable software repository for Japanese LVCSR （Large Vocabulary Continuous Speech Recognition） is introduced. It is designed as a baseline platform for research and developed by researchers of different academic institutes under a governmental support. The repository consists of a recognition engine （Julius）, Japanese acoustic models and statistical language models us well as Japanese morphological analysis tools. These modules can be easily integrated and replaced under a plug-and-play framework, which makes it possible to fairly evaluate components and to develop specific application systems. Assessment of these modules and systems in a 20000-word dictation task is reported. The software repository is freely available to the public.

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单剂量二氯化镭－223(BAY 88－8223)在去势抵抗性前列腺癌骨转移日本患者中的药代动力学研究

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中华核医学与分子影像杂志 2017年第5期37卷 318-318页

作者： Keisuke Yoshida Tomohiro Kaneta Shoko Takano Madoka Sugiura Tsuyoshi Kawano Ayako Hino Tou yamamoto kazuya Shizukuishi Masato Kaneko Christian Zurth Tomio Inoue 华中科技大学同济医学院附属协和医院核医学科 Department of Radiology Yokohama City University

目的该非盲、非随机的一期临床研究旨在评估单剂量223Ra在去势抵抗性前列腺癌骨转移日本患者中的药代动力学和辐射剂量学表现。方法研究纳入6例经组织学或细胞学证实为前列腺Ⅳ期腺癌日本患者(平均年龄72.5岁, 范围65～79岁)。2～5 min... 详细信息

目的该非盲、非随机的一期临床研究旨在评估单剂量223Ra在去势抵抗性前列腺癌骨转移日本患者中的药代动力学和辐射剂量学表现。方法研究纳入6例经组织学或细胞学证实为前列腺Ⅳ期腺癌日本患者(平均年龄72.5岁, 范围65～79岁)。2～5 min内静脉缓慢推注单一剂量的223Ra, 组1剂量为50 kBq/kg, 组2剂量为100 kBq/kg。结果经静脉注射后, 223Ra以多相式从血液中快速清除。注射后24 h, 全身残留的223Ra为注射活度的85%。生物分布结果显示, 骨骼初始摄取为52%(范围41%～57%)。223Ra在骨骼中摄取的峰值时间为给药后2 h。给药24 h内, 在小肠中可以检测到有放射性, 其他器官未检测到放射性。223Ra的主要辐射剂量在成骨细胞中。通过计算发现, 成骨细胞和红骨髓中的吸收剂量分别为0.76 Gy/MBq和0.09 Gy/MBq。结论在去势抵抗性前列腺癌骨转移的日本患者中, 223Ra(静脉注射)可在骨组织中快速达到摄取峰值, 并在24 h内通过小肠, 而其他器官无明显放射性分布。本研究显示, 日本患者器官和组织中该药物的药代动力学和吸收辐射剂量与非日本患者的数据相似。临床试验注册号:NCT01565746。

关键词： 223Ra 去势抵抗性前列腺癌转移药代动力学

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