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Radiotherapy for multiple brain metastases from hepatocellular carcinomas

Radiotherapy for multiple brain metastases from hepatocellular carcinomas

作     者:Nobuyuki Toshikuni Kazuhiko Morii Michinori Yamamoto 

作者机构:Department of Internal Medicine Center for Liver Diseases Kawasaki Hospital Kawasaki Medical SchoolOkayama Japan Department of Internal Medicine Himeji RedCross Hospital Himeji Japan Department of Internal Medicine Himeji Red Cross Hospital Himeji Japan Department of Radiology Himeji Red Cross Hospital Himeji Japan 

出 版 物:《World Journal of Gastroenterology》 (世界胃肠病学杂志(英文版))

年 卷 期:2007年第13卷第33期

页      面:4520-4522页

核心收录:

学科分类:1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

基  金:ACKN0WLEDGMENTS The authors thank Dr. Yoji Shimizu  Dr. Kazuya Takahashi and Dr. Shigeo Nakamura  Department of Neurosurgery  Himeji Red Cross Hospital  for diagnosing the brain metastases and evaluating the therapeutic effects of radiotherapy 

主  题:Hepatocellular carcinoma Brain metastasis Radiotherapy 

摘      要:A 78-year-old man with liver cirrhosis was found to have multiple hepatocellular carcinomas (HCCs) and underwent 3 sessions of transcatheter arterial chernoernbolization. Fourteen months after diagnosis, the patient presented with left herniparesis. Contrast- enhanced magnetic resonance imaging showed multiple metastases with ring-shaped enhancement in the cerebrum and cerebellum. There were no metastases to other organs. The metastatic lesions almost completely disappeared after whole-brain radiotherapy with a total dose of 50 Gy. Neurologic symptoms decreased, and the patient's quality of life improved. The patient underwent 2 more sessions of transcatheter arterial chemoembolization. Twelve months after the diagnosis of brain metastasis, the patient remains alive. The present case indicates that radiotherapy can improve quality of life and prolong survival in some patients with brain metastases from HCCs.

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