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Association of metabolic NCD risk factors with oral, breast and cervical precancers and cancers in India

Family Medicine and Community Health 2019年第4期7卷 37-45页

作者： Ashwini Kedar Roopa Hariprasad Vipin Kumar kavitha dhanasekaran Ravi Mehrotra Department of Clinical Oncology National Institute of Cancer Prevention and ResearchNoidaIndia

Objective To find an association between metabolic non-communicable disease(NCD)risk factors(high blood pressure(BP),high random blood sugar(RBS)and overweight/obesity)and oral,breast,cervical cancers/precancerous or potentially malignant conditions.Design This is an observational study using convenience sampling.The participants were screened through opportunistic or population-based screening.setting The study was conducted at a health promotion clinic(HPC)located in Northern India under the Indian Council of Medical Research.HPC is a screening clinic where screening is done for hypertension(HT),diabetes mellitus(DM),obesity,and oral,breast and cervical cancers.The study was conducted between December 2016 and January 2019.Participant The number of participants screened was 8352(6712 women and 1640 men).All consenting men and women above 18 years were included.All participants were screened for oral cancer,DM,HT and obesity.All women were also screened for breast and cervical cancers.Cervical screening was done for non-pregnant women 21 years and above with history of sexual activity.result Oral potentially malignant disease(OPMD)was the most prevalent,followed by breast cancer,oral cancer,cervical cancer and cervical precancer.High RBS had a strong association with oral cancer(OR=2.29,95%CI 1.09 to 4.82,p=0.03)and breast cancer(OR=1.95,95%CI 1.01 to 3.76,p=0.05).High BP had a strong association with breast cancer(OR=2.50,95%CI 1.43 to 4.35,p<0.0001).An inverse association was noted between oral cancer and overweight/obesity(OR=0.20,95%CI 0.08 to 0.48,p<0.0001).Current tobacco use was strongly associated with oral cancer(OR=6.51,95%CI 3.63 to 11.67,p<0.0001)and OPMD(OR=9.82,95%CI 8.13 to 11.86,p<0.0001).No association was elicited between the metabolic NCD risk factors and cervical cancer/precancer.Conclusions The study reaffirms that NCD metabolic risk factors determine oral and breast cancers.Besides NCD risk factors,current tobacco use was a strong determinant of OPMD and oral cancer.Hence,primary and primor

关键词： cervical breast cancers

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Microclimatic parameters affect Cladosporium rot development and berry quality in table grapes

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Horticultural Plant Journal 2022年第2期8卷 171-183页

作者： dhanasekaran Solairaj Ngolong Ngea Guillaume Legrand Qiya Yang Jizhan Liu Hongyin Zhang School of Food and Biological Engineering Jiangsu UniversityZhenjiang 212013JiangsuChina Key Laboratory of Modern Agricultural Equipment and Technology Ministry of EducationJiangsu UniversityZhenjiang 212013JiangsuChina

Cladosporium cladosporioides is an emerging pathogenic fungus that causes Cladosporium rot in postharvest table grapes(Vitis vinifera). However,studies investigating the infection process of C. cladosporioides are lacking. Therefore, this study aimed to elucidate the infection process by investigating the influence of microclimatic parameters(temperature, wetness and fungal age) in C. cladosporioides pathogenesis, activities of grape defense-related enzymes and grape quality during the infection. C. cladosporioides effectively infects grapes by developing distinct colonies on the artificial wounds and berry surfaces, completing its life cycle within 48 h. The C. cladosporioides disease incidence optimally occurred at 20 ℃ and 25 ℃. Wetness played an influential role in the infectivity of C. cladosporioides and 7-day-old C. cladosporioides resulted in the most serious disease incidence of table grapes. As a result of infection, the quality of grapes was affected, including berry weight, p H, titratable acidity(TA), total soluble solids(TSS), and ascorbic acid level. This infection also induced defense-related enzymes, including polyphenoloxidase(PPO), peroxidase(POD), phenylalanine ammonialyase(PAL), and catalase(CAT), at certain times. The findings of this study demonstrated that Cladosporium rot development depended on the microclimatic parameters of grapes, significantly affected the grape quality and induced grape's defense-related enzymes.

关键词： Cladosporium cladosporioides Table grape Pathogenesis Infection

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Content-Based Movie Recommendation System Using MBO with DBN

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Intelligent Automation & Soft Computing 2023年第3期35卷 3241-3257页

作者： S.Sridhar D.dhanasekaran G.Charlyn Pushpa Latha Department of CSE Saveetha School of EngineeringSaveetha Institute of Medical and Technical SciencesChennaiIndia Saveetha Institute of Medical and Technical Sciences ChennaiIndia Department of IT Saveetha School of EngineeringSaveetha Institute of Medical and Technical SciencesChennaiIndia

The content-basedﬁltering technique has been used effectively in a variety of Recommender Systems(RS).The user explicitly or implicitly provides data in the Content-Based Recommender System.The system collects this data and creates a proﬁle for all the users,and the recommendation is generated by the user proﬁle.The recommendation generated via content-basedﬁltering is provided by observing just a single user’s proﬁle.The primary objective of this RS is to recommend a list of movies based on the user’s preferences.A con-tent-based movie recommendation model is proposed in this research,which recommends movies based on the user’s proﬁle from the Facebook platform.The recommendation system is built with a hybrid model that combines the Mon-arch Butterﬂy Optimization(MBO)with the Deep Belief Network(DBN).For feature selection,the MBO is utilized,while DBN is used for classiﬁcation.The datasets used in the experiment are collected from Facebook and MovieLens.The dataset features are evaluated for performance evaluation to validate if data with various attributes can solve the matching recommendations.Eachﬁle is com-pared with features that prove the features will support movie recommendations.The proposed model’s mean absolute error(MAE)and root-mean-square error(RMSE)values are 0.716 and 0.915,and its precision and recall are 97.35 and 96.60 percent,respectively.Extensive tests have demonstrated the advantages of the proposed method in terms of MAE,RMSE,Precision,and Recall compared to state-of-the-art algorithms such as Fuzzy C-means with Bat algorithm(FCM-BAT),Collaborativeﬁltering with k-NN and the normalized discounted cumulative gain method(CF-kNN+NDCG),User proﬁle correlation-based similarity(UPCSim),and Deep Autoencoder.

关键词： Movie recommendation monarch butterﬂy optimization deep belief network facebook movielens deep learning

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Unveiling the redox electrochemistry of 1D,urchin-like vanadium sulfide electrodes for high-performance hybrid supercapacitors

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Journal of Energy Chemistry 2023年第4期79卷 569-580页

作者： K.Karuppasamy dhanasekaran Vikraman Sajjad Hussain Balamurugan Thirumalraj P.Santhoshkumar Hemalatha Parangusan Hyun-Chang Park Jongwan Jung Hyun-Seok Kim Division of Electronics and Electrical Engineering Dongguk University-SeoulSeoul 04620Republic of Korea Department of Nanotechnology and Advanced Materials Engineering Sejong UniversitySeoul 05006Republic of Korea School of Materials Science&Engineering Kookmin UniversitySeoul 02707Republic of Korea Millimeter-Wave Innovation Technology Research Center(MINT) Dongguk University-SeoulSeoul 04620Republic of Korea Qatar University Young Scientist Center(QUYSC) Qatar UniversityP.O.Box 2713DohaQatar

Exploring novel versatile electrode materials with outstanding electrochemical performance is the key to the development of advanced energy conversion and storage devices.In this work,we aim to construct new-fangled one-dimensional(1D)quasi-layered patronite vanadium tetrasulfide(VS_(4))nanostructures by using different sulfur sources,namely thiourea,thioacetamide,and L-cysteine through an ethyleneaminetetraacetic-acid(EDTA)-mediated solvothermal process.The as-prepared VS4exhibits several unique morphologies such as urchin,fluffy nanoflower,and polyhedron with appropriate surface areas.Among the prepared nanostructures,the VS_(4)-1@NF nanostructure exhibited excellent electrochemical properties in 6 M KOH solution,and we explored its redox electrochemistry in detail.The asprepared VS_(4)-1@NF electrode exhibited battery-type redox characteristics with the highest capacity of280 C g^(-1)in a three-electrode assembly.Moreover,it offered a capacity of 123 F g^(-1)in a hybrid twoelectrode set-up at 1 A g^(-1)with the highest specific energy and specific power of 38.5 W h kg^(-1)and750 W kg^(-1),respectively.Furthermore,to ensure the practical applicability and real-world performance of the prepared hybrid AC@NF//VS_(4)-1@NF cell,we performed a cycling stability test with more than 5,000galvanostatic charge–discharge cycles at 2 A g^(-1),and the cell retained around 84.7%of its capacitance even after 5,000 cycles with a CE of 96.1%.

关键词： Patronite Redox electrochemistry Urchin VS_(4) 1D material Mesoporous

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Exploring the experimental study and density functional theory calculations of symmetric and asymmetric chalcogen atoms interacted molybdenum dichalcogenides for lithium-ion batteries

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Journal of Materials Science & Technology 2023年第31期162卷 44-56页

作者： dhanasekaran Vikraman Sajjad Hussain Zeesham Abbas K.Karuppasamy Woo-Seok Kang P.Santhoshkumar A.Kathalingam Jongwan Jung Hyun-Seok Kim Division of Electronics and Electrical Engineering Dongguk University-SeoulSeoul 04620Republic of Korea Department of Nanotechnology and Advanced Materials Engineering Sejong UniversitySeoul 05006Republic of Korea Hybrid Materials Center(HMC) Sejong UniversitySeoul 05006Republic of Korea Millimeter-wave Innovation Technology(MINT)Research Center Dongguk University-SeoulSeoul 04620Republic of Korea

Two-dimensional asymmetric chalcogen atoms attached to Janus nanoparticles have fascinated research attention owing to their distinctive properties and characteristics for various applications.This paper proposed a facile synthesis to produce efficient molybdenum-based symmetric and asymmetric chalcogens bounded by X Mo X and TeMo X nanostructures.Subsequently,the fabricated X Mo X and TeMo X nanostruc-tures were employed as anodes for lithiumion batteries(LIBs).Assembled LIBs using TeMoS and TeMoSe Janus anodes achieved 2610 and 2073 mAh g^(-1)reversible capacity at 0.1 A g^(-1),respectively for the halfcell configuration,which is outstanding performance compared with previous reports.Superior rate capability performances at 0.1-20 A g^(-1)and exceptional cycling solidity confirmed high charge and discharge capacities for TeMo X Janus lithium-ion battery anodes.In addition,the full cell device with TeMoS//LiCoO_(2)configuration explored the discharge capacity of 1605 mAh g^(-1)at 0.1 A g^(-1)which suggests their excellent electrochemical characteristics.The density functional theory approximations established the significance of assembled symmetric and asymmetric chalcogen atoms interacted with X Mo X and TeMo X anode materials for LIBs.Thus,the present investigation supports a new approach to creating two-dimensional materials based on asymmetric chalcogen atoms with core metal to effectively increase desirable energy storage characteristics.

关键词： TeMoS TeMoSe Janus Li-ion battery

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Larvicidal,ovicidal and pupicidal activities of Gliricidia sepium(Jacq.)(Leguminosae) against the malarial vector,Anopheles stephensi Liston(Culicidae:Diptera)

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Asian Pacific Journal of Tropical Medicine 2012年第8期5卷 598-604页

作者： Kaliyamoorthy Krishnappa Shanmugam dhanasekaran Kuppusamy Elumalai Unit of Entomotoxicity Department of Zoology Govt.Thirumagal Mills College Vellore-632607 TamilnaduIndia Center for Entomotoxicity Studies Department of ZoologyAnnamalai UniversityAnnamalainagar-608 002 TamilnaduIndia

Objective:To investigate the potentiality of mosquitocidal activity of Gliricidia sepium（C.sepium）（Jacq.）（Leguminosae）.Methods:Twenty five early third instar larvae of Anopheles stephensi （An.stephensi） were exposed to various concentrations（50-250 ppm） and the 24 h LC50 values of the G.sepium extract was determined by probit analysis.The ovicidal activity was determined against An.stephensi to various concentrations ranging from 25-100 ppm under laboratory conditions.The eggs hatchabilily was assessed 48 h post treatment.The pupicidal activity was determined against An.stephensi to various concentrations ranging from 25-100 ppm.Mortality of each pupa was recorded after 24 h of exposure to the extract.Results:Results pertaining to the experiment clearly revealed that ethanol extract showed significant larvicidal,ovicidal and pupicidal activity against the An.stephensi.Larvicidal activity of ethanol extracts of G.sepium showed maximum mortality in 250 ppm concentration（96.0±2.4）%.Furthermore,the LC50 was found to be 121.79 and the LC50 value was recorded to be 231.98 ppm.Ovicidal activity of ethanol extract was assessed by assessing the egg hatchabilily.Highest concentration of both solvent extracts exhibited 100%ovicidal activity.Similarly,pupae exposed to different concentratioiLs of ethanol extract were found dead with 58.10%adult emergence when it was treated with 25 ppm concentration.Similarly,18.36（n=30;61.20%）;21.28（70.93） and 27.33（91.10） pupal mortality was recorded from the experimental pupae treated with 50,75 and 100 ppm concentration of extracts. Three fractions have been tested for their larvicidal activity of which the Fraction 3 showed the LC50 and LC90 values of 23.23 and 40.39 ppm.With regard to the ovicidal effect fraction 3 showed highest ovicidal activities than the other two fractions.Furthermore,there were no hatchabilily was recorded above 50 ppm（100%egg mortality） in the experimental group.Statistically significant pupicidal activity

关键词： Anopheles stephensi Gliricidia sepium Crude extract Fractions Larvicidal activity Ovicidal activity Pupicidal activity

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Nonsaturation Throughput Enhancement of IEEE 802.11b Distributed Coordination Function for Heterogeneous Traffic under Noisy Environment

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International Journal of Automation and computing 2010年第1期7卷 95-104页

作者： dhanasekaran Senthilkumar A. Krishnan Department of Electronics and Communication Engineering K.S.Rangasamy College of Technology

In this paper, we propose a mechanism named modified backoff （MB） mechanism to decrease the channel idle time in IEEE 802.11 distributed coordination function （DCF）. In the noisy channel, when signal-to-noise ratio （SNR） is low, applying this mechanism in DCF greatly improves the throughput and lowers the channel idle time. This paper presents an analytical model for the performance study of IEEE 802.11 MB-DCF for nonsaturated heterogeneous traffic in the presence of transmission errors. First, we introduce the MB-DCF and compare its performance to IEEE 802.11 DCF with binary exponential backoff （BEB）. The IEEE 802.11 DCF with BEB mechanism suffers from more channel idle time under low SNR. The MB-DCF ensures high throughput and low packet delay by reducing the channel idle time under the low traffic in the network. However, to the best of the authors＇ knowledge, there are no previous works that enhance the performance of the DCF under imperfect wireless channel. We show through analysis that the proposed mechanism greatly outperforms the original IEEE 802.11 DCF in the imperfect channel condition. The effectiveness of physical and link layer parameters on throughput performance is explored. We also present a throughput investigation of the heterogeneous traffic for different radio conditions.

关键词： IEEE 802.11 medium access control （MAC） distributed coordination function （DCF） nonsaturated traffic heteroge- neous traffic signal-to-noise ratio （SNR） binary exponential backoff （BEB）.

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Pressure pulsation in stages of electric submersible pump at shut-off under various speeds

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排灌机械工程学报 2020年第7期38卷 649-657页

作者： dhanasekaran Arumugam KUMARASWAMY Sivasailam Department of Mechanical Engineering Chennai Institute of TechnologyChennaiTamilnadu 600069India Department of Mechanical Engineering Indian Institute of Technology MadrasChennaiTamilnadu 600036India

Electric submersible pumps were widely used in agricultural fields,petroleum and various other industries. The pressure pulsation caused fatigue failure due to vibration in electric submersible pump and affects the life and performance of its system. The objective of this study was to experimentally investigate the characteristics of pressure pulsation which were generated at various stages of a multistage electric submersible pump during closed valve operation at different speeds. An electric submersible pump with five stages was selected for conducting experiments. A variable frequency drive( VFD)was used to operate the electric submersible pump at five different speed settings from 40 to 60 Hz. Piezoresistive pressure transducers were mounted at each stage of the electric submersible pump to capture the unsteady pressure signals. At each speed setting,the electric submersible pump was operated at the shut-off condition and the signals of unsteady pressure from all the five stages were captured. A fast fourier transformation( FFT) was carried out on the pressure signals to convert into frequency domain.From the spectra of pressure pulsation signals,the characteristics of pressure pulsation are obtained for each stage and for various speed settings which were then used to understand its variation with speed and stages.

关键词： electric submersible pump shut-off stage pressure pulsation variable frequency

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Throughput Analysis of IEEE 802.11 Multirate WLANs with Collision Aware Rate Adaptation Algorithm

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International Journal of Automation and computing 2010年第4期7卷 571-577页

作者： dhanasekaran Senthilkumar A.Krishnan Department of Electronics and Communication Engineering K.S.Rangasamy College of Technology

This paper presents a mathematical model that analyzes the throughput of the IEEE 802.11b distributed coordination function （DCF） with the collision aware rate adaptation （CARA） algorithm. IEEE 802.11 WLANs provide multiple transmission rates to improve system throughput by adapting the transmission rate to the current channel conditions. The system throughput is determined by some stations using low transmission rates due to bad channel conditions. CARA algorithm does not disturb the existing IEEE 802.11b formats and it can be easily incorporated into the commercial wireless local area networks （WLAN） devices. Finally, we verify our findings with simulation.

关键词： Distributed coordination function （DCF） IEEE 802.11 collision aware rate adaptation （CARA） multirate medium access control （MAC）.

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COVID-19 induced renal injury differs from that in other viral-infections

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Emergency and Critical Care Medicine 2022年第1期2卷 23-31页

作者： Rachel S.Parise Manoj Govindarajulu Sindhu Ramesh Tony Thomas Timothy Moore Muralikrishnan dhanasekaran Department of Drug Discovery and Development Auburn University Harrison School of PharmacyWalker BuildingAuburnAlabamaUSA Department of Mechanical Engineering Auburn UniversityAuburnAlabamaUSA

Background:Kidney injuries caused by several viral diseases have been reported worldwide among all age groups,races,and genders.Of particular importance is coronavirus disease 2019(COVID-19),and its prevalence in communities infecting all patient populations with symptoms ranging from asymptomatic to severe,including complications and mortality.Methods:Data were acquired from PubMed,Scopus,Google Scholar,Centers for Disease Prevention and Control(CDC),and Lexi-Comp using the following search terms:“COVID-19 and renal pathology,”“COVID-19 induced kidney disease,”“Viral infection induced kidney disease,”and“Viral infection induced renal damage.”Titles and abstracts were manually analyzed as per the exclusion and inclusion criteria of relevant articles;relevance of articles included studies on the pathology of a specific viral infection and the impact of the virus on the adult renal system.Results:The mechanisms for renal disease due to COVID-19 include direct renal tubular injury,cytokine storm,inflammation,thrombosis vs.acute tubular necrosis,thrombotic events,and direct renal injury.Although some mechanisms behind renal dysfunction among the studied viral infections are similar,the prevalence rates of kidney injury or damage differ.This might be described by recommended prophylactic and therapeutic approaches that can alter the viral infection characteristics and possibly the impact a particular organ system.Conclusion:The patient population at risk was old in age and had a high body mass index.The mechanisms associated with renal dysfunction are similar,including direct renal injury through angiotensin converting enzyme 2(ACE2)entry,inflammation,and thrombosis.The renal pathology of coronaviruses that differs from that of other prevalent viral infections is the activation of cytokine storm,which causes elevations of a greater number and different kinds of cytokines than other viral infections.

关键词： COVID-19 Kidney damage Renal damage Renal pathology

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