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Follicle-stimulating hormone(FSH)levels prior to prostatectomy are not related to long-term oncologic or cardiovascular outcomes for men with prostate cancer

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Asian Journal of Andrology 2022年第1期24卷 21-25页

作者： kassim kourbanhoussen France-Hélène Joncas Christopher JD Wallis Hélène Hovington Francois Dagenais Yves Fradet Chantal Guillemette Louis Lacombe Paul Toren Department of Surgery Faculty of MedicineUniversitéLavalCHU de Québec Research CenterOncology DivisionQuebec City G1R3S1Canada Department of Urology Vanderbilt University Medical CenterNashvilleTN 37232USA Institut Universitaire Cardiologie et Pneumologie de Québec Quebec City G1V 4G5Canada Faculty of Pharmacy UniversitéLavalCHU de Québec Research CenterQuebec City G1V 4G2Canada

Prior research suggests a link between circulating levels of follicle-stimulating hormone(FSH)and prostate cancer *** levels may also explain some of the observed differences in cardiovascular events among men treated with gonadotropin-releasing hormone(GnRH)antagonists compared to GnRH *** study evaluates the association between preoperative FSH and long-term cardiovascular and oncologic outcomes in a cohort of men with long follow-up after radical *** performed a cohort study utilizing an institutional biobank with annotated clinical *** levels were measured from cryopreserved plasma and compared with sex steroids previously measured from the same *** in oncologic outcomes between tertiles of FSH levels were compared using adjusted cox regression *** adverse cardiovascular events(MACE)were similarly assessed using hospital admission diagnostic codes.A total of 492 patients were included,with a median follow-up of 13.1(interquartile range:8.9–15.9)*** sulfate(DHEA-S)levels,but not other androgens,negatively correlated with FSH levels on linear regression analysis(P=0.03).There was no association between FSH tertile and outcomes of biochemical recurrence,time to castrate-resistant prostate cancer,or time to *** were identified in 50 patients(10.2%),with a mean time to first event of 8.8 *** association with FSH tertile and occurrence of MACE was *** results do not suggest that preoperative FSH levels are significantly associated with oncologic outcomes among prostate cancer patients treated with radical prostatectomy,nor do these levels appear to be predictors of long-term cardiovascular risk.

关键词： cardiovascular events follicle-stimulating hormone prostate cancer recurrence

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Occurrence of viable but non-culturable(VBNC)pathogenic bacteria in tap water of public places

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Frontiers of Environmental Science & Engineering 2024年第3期18卷 115-129页

作者： Lizheng Guo Xinyan Xiao kassim Chabi Yiting Zhang Jingjing Li Su Yao Xin Yu China National Research Institute of Food and Fermentation Industries Co. Ltd.China Center of Industrial Culture CollectionBeijing 100015China Key Laboratory of Urban Environment and Health Institute of Urban EnvironmentChinese Academy of SciencesXiamen 361021China College of Environment&Ecology Xiamen UniversityXiamen 361102China

Viable but non-culturable(VBNC)bacteria have been detected in source water and effluent of drinking water treatment processes,leading to significant underestimation of viable cell *** information exists on VBNC bacteria in tap water,particularly in public *** address this gap,a comprehensive nine-month study was conducted in a major city in south-eastern China,using culture-based and quantitative PCR with propidium monoazide(PMA)dye ***-five samples were collected from five representative public places(railway station,campus,hospital,shopping mall,and institution).The findings revealed that culturable bacteria represented only 0–17.51%of the viable 16S rRNA genes,suggesting that the majority of viable bacteria existed in an uncultured or VBNC ***,opportunistic pathogens such as Escherichia coli,Enterococcus faecalis,Pseudomonas aeruginosa,Salmonella sp.,and Shigella *** primarily detected as VBNC cells,with concentrations ranging from 1.03×10^(0)to 3.01×10^(3),1.20×10^(0)to 1.42×10^(2),1.32×10^(0)to 8.82×10^(0),1.00×10^(0)to 6.71×10^(1),and 2.07×10^(0)to 1.93×10^(2)cell equivalent/100 mL,*** *** was observed in tap water after prolonged stagnation,indicating potential risks associated with bacterial *** and temporal factors accounted for 17.1%and 26.0%,respectively,of the variation in tap water community structure during the sampling period,as revealed by 16S rRNA amplicon *** study provides quantitative insights into the occurrence of VBNC bacteria in tap water and highlights the need for more sensitive monitoring methods and microbial control techniques to enhance tap water safety in public locations.

关键词： VBNC Pathogenic bacteria PMA treatment Public tap water Community structure

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Smart Farming for Sustainable Rice Production:An Insight into Application,Challenge,and Future Prospect

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Rice science 2024年第1期31卷 47-61页

作者： Norhashila HASHIM Maimunah Mohd ALI Muhammad Razif MAHADI Ahmad Fikri ABDULLAH Aimrun WAYAYOK Muhamad Saufi Mohd kassim Askiah JAMALUDDIN Department of Biological and Agricultural Engineering/SMART Farming Technology Research Centre Faculty of EngineeringUniversiti Putra MalaysiaSelangor 43400Malaysia Department of Food Sciences Faculty of Science and TechnologyUniversiti Kebangsaan MalaysiaSelangor 43600Malaysia Department of Resource Management&Consumer Studies Faculty of Human EcologyUniversiti Putra MalaysiaSelangor 43400Malaysia

Rice has a huge impact on socio-economic growth,and ensuring its sustainability and optimal utilization is *** review provides an insight into the role of smart farming in enhancing rice *** applications of smart farming in rice production including yield estimation,smart irrigation systems,monitoring disease and growth,and predicting rice quality and classifications are *** challenges of smart farming in sustainable rice production to enhance the understanding of researchers,policymakers,and stakeholders are *** efforts have been exerted to combat the issues in rice production in order to promote rice sector *** effective implementation of smart farming in rice production has been facilitated by various technical advancements,particularly the integration of the Internet of Things and artificial *** future prospects of smart farming in transforming existing rice production practices are also *** the utilization of smart farming,the rice industry can attain sustainable and resilient production systems that could mitigate environmental impact and safeguard food ***,the rice industry holds a bright future in transforming current rice production practices into a new outlook in rice smart farming development.

关键词： rice production smart farming food security agriculture sustainability

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Numerical Modeling and Technico-Economic Analysis of a Hybrid Energy Production System for Self-Consumption: Case of Rural Area in the Comoros

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Journal of Power and Energy Engineering 2024年第5期12卷 24-59页

作者： Fahad Maoulida Mohamed Aboudou kassim Rabah Djedjig Ahmed Ihlal Mohammed El Ganaoui LERMAB Laboratory of Studies and Research on Wood Material IUT of Longwy University of Lorraine Cosnes-et-Romain Longwy France LEMA Energy and Applied Mechanics Laboratory Faculty of Sciences and Techniques University of Comoros Moroni Comoros IREMIS Institute University of Mayotte Mayotte France LMER Laboratory of Materials and Renewable Faculty of Sciences University Ibn Zohr BP Agadir Morocco

This study aims to provide electricity to a remote village in the Union of Comoros that has been affected by energy problems for over 40 years. The study uses a 50 kW diesel generator, a 10 kW wind turbine, 1500 kW photovoltaic solar panels, a converter, and storage batteries as the proposed sources. The main objective of this study is to conduct a detailed analysis and optimization of a hybrid diesel and renewable energy system to meet the electricity demand of a remote area village of 800 to 1500 inhabitants located in the north of Ngazidja Island in Comoros. The study uses the Hybrid Optimization Model for Electric Renewable (HOMER) Pro to conduct simulations and optimize the analysis using meteorological data from Comoros. The results show that hybrid combination is more profitable in terms of margin on economic cost with a less expensive investment. With a diesel cost of $1/L, an average wind speed of 5.09 m/s and a solar irradiation value of 6.14 kWh/m2/day, the system works well with a proportion of renewable energy production of 99.44% with an emission quantity of 1311.407 kg/year. 99.2% of the production comes from renewable sources with an estimated energy surplus of 2,125,344 kWh/year with the cost of electricity (COE) estimated at $0.18/kWh, presenting a cost-effective alternative compared to current market rates. These results present better optimization of the used hybrid energy system, satisfying energy demand and reducing the environmental impact.

关键词： Hybrid System Rural Area Electrification Comoros Techno-Economic Analysis PV-Wind-Diesel-Battery Meteorological Data HOMER Energy Pro

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Pleomorphic Adenoma of the Salivary Glands: Two Atypical Locations

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International Journal of Otolaryngology and Head & Neck Surgery 2024年第3期13卷 251-257页

作者： Sidibé Youssouf Diarra Abraham Samaké Djibril Sanogo Boubacar Traoré Abdoul Moumine Diarra kassim Coulibaly Bourama Diakité Youssouf Keita Mohamed Amadou Department of ENT and Head and Neck Surgery Mother-Child University Hospital “ Le Luxembourg&#8221 Bamako Mali Faculty of Medicine and Odontostomatology Bamako Mali Department of ENT and Head and Neck Surgery The Mali-Gavardo Hospital Bamako Mali Ministry of Higher Education and Scientific Research Bamako Mali ENT and Head and Neck Surgery Department of the Commune V Reference Health Center (CSRef CV) Bamako Mali Department of ENT and Head and Neck Surgery at CHU Gabriel Touré Bamako Mali Department of Anatomy and Pathological Cytology Gabriel Tour&#233 University Hospital Center Bamko Mali Department of Oral Surgery Sikasso Regional Hospital Sikasso Mali

Pleomorphic adenoma is the most common tumor of the salivary glands, accounting for approximately 50% of salivary gland lesions. It develops mainly in the salivary glands: parotid (80%), submaxillary (10%), sublingual (1%) and in the accessory oral-pharyngeal glands (9%). The aim of this work was to report 2 cases of pleomorphic adenoma of atypical location and then to discuss the difficulties linked to its diagnostic and therapeutic management in the Malian context. They were a 40-year-old man and a 72-year-old woman. They were admitted to the ENT department of the “Luxembourg Mere-infant” hospital for oropharyngeal swelling for the first and swelling of the palate for the second. The clinical expression was a swelling in both cases, of a hard, mobile consistency with healthy mucosa on their surface. The remainder of the physical examination was unremarkable. The diagnosis of a tumor of the oropharynx and palate was made following clinical radiological examinations. The histopathological examination of the surgical specimen made it possible to make the diagnosis of pleomorphic adenoma of the palate and the left palatine tonsil. The follow-up surgery was straightforward, with a favorable outcome. Pleomorphic adenomas are relatively rare benign tumors of the accessory salivary glands;their clinical expression remains swelling. Therapeutic management is surgery and the diagnosis is confirmed by histopathological examination.

关键词： Pleomorphic Adenoma Palate Tonsil Mali

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Seroprevalence of SARS-COV-2 Exposure among “High-Risk” Populations (Healthcare Workers, People Who Attend Markets, and School Children) in Zanzibar

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Advances in Infectious Diseases 2024年第1期14卷 34-55页

作者： Ame Masemo Solomon Mwakasungula Khamis Kheir Erick Mgina Nahya Khamis Irabi kassim Bihila Bakar Khamis Salim Sarah Mswata Kibwana Omar Theckla Kazimoto Linzy Elton Honorati Masanja Mayassa Ally Zanzibar Health Research Institute Binguni Zanzibar Ifakara Health Institute Bagamoyo Tanzania National Institute for Medical Research Muhimbili Centre Dar es Salaam Tanzania Binguni Public Health Laboratory Binguni Zanzibar Department of Microbiology Mnazi Mmoja Hospital Stone Town Zanzibar Centre for Clinical Microbiology Royal Free Hospital Campus University College London London UK

In Zanzibar, from the start of the pandemic in March 2020 to the time of sampling in December 2020, SARS-CoV-2 seroprevalence data was limited. We conducted a seroprevalence study to evaluate the magnitude of SARS-CoV-2 exposure among healthcare workers, school children, and people who attended general markets in Zanzibar. The objectives of the study were to analyse the total antibodies from selected higher-risk population groups in order to determine magnitude in SARS CoV-2 exposure. Blood samples were collected from eligible and consented participants (adults and children), and their serum was analyzed for total antibodies against SARS-CoV-2 using ELISA. A questionnaire was used to collect participants’ demographic and clinical data. The overall SARS-CoV-2 seroprevalence across all age groups was 33%, and a higher seroprevalence was observed in the 40 - 49 years’ age group relative to other ages as well as in those who attended markets. A runny nose (18.8% of participants) was the most frequently reported SARS-CoV-2 infection-related symptom. Multivariable analysis showed significantly higher odds of infection in people living in urban districts. The findings provide insight into SARS-CoV-2 infection among school children, health workers, and people who attended markets in Zanzibar in the early stages of the pandemic. Exposure in these groups might have been influenced by infection and prevention strategies taken by the government, as well as shopping behavior, school overcrowding, and population density in urban settings. The study had methodological limitations, including cross-sectional design. Further, well-designed, longitudinal studies are recommended to understand exposure and transmission at a population level.

关键词： SARS-CoV-2 Seroprevalence Zanzibar ELISA COVID-19

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Uplift of Symmetrical Anchor Plates by Using Grid-Fixed Reinforced Reinforcement in Cohesionless Soil

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China Ocean Engineering 2014年第1期28卷 115-126页

作者： Hamed Niroumand Khairul Anuar kassim Department of Geotechnical Engineering Faculty of Civil EngineeringUniversity of Technology Malaysia

Uplift response of symmetrical anchor plates with and without grid fixed reinforced （GFR） reinforcement was evaluated in model tests and numerical simulations by Plaxis. Many variations of reinforcement layers were used to reinforce the sandy soil over symmetrical anchor plates. In the current research, different factors such as relative density of sand, embedment ratios, and various GFR parameters including size, number of layers, and the proximity of the layer to the symmetrical anchor plate were investigated in a scale model. The failure mechanism and the associated rupture surface were observed and evaluated. GFR, a tied up system made of fiber reinforcement polymer （FRP） strips and end balls, was connected to the geosynthetic material and anchored into the soil. Test results showed that using GFR reinforcement significantly improved the uplift capacity of anchor plates. It was found that the inclusion of one layer of GFR, which rested directly on the top of the anchor plate, was more effective in enhancing the anchor capacity itself than other methods. It was found that by including GFR the uplift response was improved by 29%. Multi layers of GFR proved more effective in enhancing the uplift capacity than a single GFR reinforcement. This is due to the additional anchorage provided by the GFR at each level of reinforcement. In general, the results show that the uplift capacity of symmetrical anchor plates in loose and dense sand can be significantly increased by the inclusion of GFR. It was also observed that the inclusion of GFR reduced the requirement for a large L/D ratio to achieve the required uplift capacity. The laboratory and numerical analysis results are found to be in agreement in terms of breakout factor and failure mechanism pattern.

关键词： grid fixed reinforced (GFR) Plaxis fiber reinforcement polymer (FRP) uplift response anchor plate

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Ear Cholesteatoma Surgery in South Sahara: Our Experience in Bamako

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International Journal of Otolaryngology and Head & Neck Surgery 2024年第4期13卷 293-303页

作者： kassim Diarra Oumou Coulibaly Yaya Dembele Nfaly Konaté Sidibe Youssouf Saydi Ag Mohamed Harouna Sanogo Abraham Diarra Ibrahim Fofana Moussa Bourama Keita Youssouf Traore Fatogoma Issa Koné Boubacary Guindo Siaka Soumaoro Doumbia Kadidiatou Singare Mohamed Amadou Keita ORLCCF Department Gabriel Toure University Hospital Bamako Mali ORLCCF Unit Kati Army Polyclinics Kati Mali ENT-CCF Department CHU Luxembourg Bamako Mali ORLCCF Service of the Reference Center of Commune VI Sogoniko Bamako Mali

In Mali, cholesteatoma surgery remains a challenge due to the limited number of otological practitioners, and the low socio-economic level of patients reflecting the difficulties in performing CT or MRI for post-operative follow-up. We therefore initiated this work with the objective of analyzing, through a broad bibliographic review, the clinical, paraclinical, topographical, therapeutic and progressive aspects of a series of ear cholesteatoma. Materials and Method: This was a retrospective and prospective, descriptive study that took place in the ENT and head and neck surgery department of the Gabriel Touré University Hospital over 36 months from November 2020 to October 2023. These were patients admitted to the department for chronic cholestematous otitis media. Result: In total, we collected 34 files of patients admitted for cholesteatoma. This represented 9% of cases compared to all otological surgeries carried out during the same period, i.e. 362 cases. The average age of our patients was 35.31 years, with extremes ranging from 7 years to 80 years, there were 24 men and 10 women, i.e. a M/F ratio of 2.4. The average time to diagnosis was 7 years. The main functional signs were dominated by chronic fetid purulent otorrhea associated with hypoacusis in 94.6% of cases. One case of meningeal complication and three cases of cerebral empyema were reported. Clinically, a postero-superior and marginal tympanic perforation was observed in 53%, a retraction pocket in 5.9%, the sentinel polyp in 9%, and a non-marginal tympanic perforation in 32%. Pure-tone audiometry performed preoperatively for all patients showed conductive hearing loss in 83%. In 82% of cases we created a recess with the creation of a mini box. An ossiculoplasty was performed immediately with fragments of cartilage. The postoperative course found the disappearance of otorrhea (88.23%), the persistence of otorrhea in one case, two cases of facial paralysis, and one case of tinnitus. We did not identify

关键词： Cholesteatoma CT TTO TTF

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Ultimate bearing capacity of strip footing resting on clay soil mixed with tire-derived aggregates

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Frontiers of Structural and Civil Engineering 2021年第4期15卷 1016-1024页

作者： Ali AREFNIA Ali DEHGHANBANADAKI Khairul Anuar kassim Department of Geotechnics&Transportation School of Civil EngineeringFaculty of EngineeringUniversiti Teknologi MalaysiaSkudai81310Malaysia Department of Civil Engineering Roudehen BranchIslamic Azad UniversityTehranIran Department of Civil Engineering Damavand BranchIslamic Azad UniversityDamavandTehranIran

This study investigated the use of recycled tire-derived aggregate(TDA)mixed with kaolin as a method of increasing the ultimate bearing capacity(UBC)of a strip *** 1g physical modeling tests were prepared in a rigid box of 0.6 m×0.9 m in plan and 0.6 m in *** sample preparation,0%,20%,40%,or 60%(by weight)of powdery,shredded,small-sized granular(G 1–4 mm)or large-sized granular(G 5–8 mm)TDA was mixed with the kaolin.A strip footing was then placed on the stabilized kaolin and was caused to fail under stress-controlled conditions to determine the UBC.A rigorous 3D finite element analysis was developed in Optum G-3 to determine the UBC values based on the experimental test *** experimental results showed that,except for the 20%powdery TDA,the TDA showed an increase in the UBC of the strip *** kaolin mixed with 20%G(5–8 mm),the UBC showed a threefold increase over that for the unreinforced *** test with 20%G(1–4 mm)recorded the highest subgrade *** was observed that the UBC calculated using finite element modeling overestimated the experimental UBC by an average of 9%.

关键词： kaolin physical modeling tests stabilization numerical modeling

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Critical review of cyclist speed measuring techniques

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Journal of Traffic and Transportation Engineering(English Edition) 2020年第1期7卷 98-110页

作者： Ali kassim Hasan Tayyeb Mubark Al-Falahi Department of Civil and Environmental Engineering Carleton UniuersityOttawaON K1S 5B6Canada Department of Civil Engineering Umm Al-Qura UniversityMakkahSaudi Arabia Department of Urban Planning&Municipalities Municipal Operations SectorMadinat Zayed Center-Technical Services DepartmentAbu-DhabiUnited Arab Emirates

There is a growing global interest in developing and accommodating sustainable modes of *** is an important mode of travel which offers powerful solutions to chronic traffic problems of congestion and *** accuracy of cyclist position is considered as an important parameter for the calculation of cyclist *** speed data is required for precise design of traffic control measures,for safety studies,and for sight distance *** speed measurement techniques and results are found in the *** study critically examines peer-reviewed studies which discuss different techniques for measuring cyclist *** review covers the accuracy of the measurement techniques and highlights limitations of the reviewed *** identified limitations are classified as:limited range of movement directions,selection of observed cyclists,seasonal variation in measurements,completeness of results reporting,reporting of equipment limitations,and measurement *** study summarizes previous findings of cyclist speed *** study also reviews the level of automation in speed *** technique involving a human input during the field data collection or analysis to estimate cyclist speed is classified as a *** categories for semiautomated and automated measurement techniques are ***-analysis was conducted to test whether reported cyclist speed depends on where they were recorded;intersections or road *** result of the unpaired t-test showed that there is no significant difference between the means of the cyclists speed at road sections and signalized intersections at the 95%of confidence *** study emphasizes the growing importance of the use of automated computer vision techniques for speed *** paper contrasts the advantages of computer vision techniques with other measurement techniques.

关键词： Transportation engineering Cyclist speed Video analysis Signalized intersection

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